3BK8A

Urate oxidase aza-xanthine complex in cyanide
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
295
structure length
295
Chain Sequence
SAVKAARYGKDNVRVYKVHKDEKTGVQTVYEMTVCVLLEGEIETSYTKADNSVIVATDSIKNTIYITAKQNPVTPPELFGSILGTHFIEKYNHIHAAHVNIVCHRWTRMDIDGKPHPHSFIRDSEEKRNVQVDVVEGKGIDIKSSLSGLTVLKSTNSQFWGFLRDEYTTLKETWDRILSTDVDATWQWKNFSGLQEVRSHVPKFDATWATAREVTLKTFAEDNSASVQATMYKMAEQILARQQLIETVEYSLPNKHYFEIDLSWHKGLQNTGKNAEVFAPQSDPNGLIKCTVGRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Uricase
publication title Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: Mechanistic implications
pubmed doi rcsb
source organism Aspergillus flavus
total genus 80
structure length 295
sequence length 295
ec nomenclature ec 1.7.3.3: Factor independent urate hydroxylase.
pdb deposition date 2007-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01014 Uricase Uricase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.270.10 Alpha Beta Roll Urate Oxidase Urate Oxidase; 3bk8A00
2FXLA 2ZKAA 4PUVA 1VAXA 3PLJA 1WS3A 2ICQA 3P9FA 4D19A 4CW2A 3BJPA 4R8XA 2YZBA 2IBAA 3PK4A 2FUBA 4POEA 1WRRA 4D17A 4OP9A 4OP6A 3PLGA 3PKLA 3D2OA 1R4SA 4CW6A 1VAYA 4CW3A 4N3MA 5K95A 3PLMA 5K9GA 2YZDA 1R56A 4D12A 1XXJA 3F2MA 3CKUA 3L9GA 5LL1A 3PKGA 3P9OA 5M98A 2YZEA 4PR8A 3PKUA 3PJKA 3LBGA 3LD4A 3PK5A 3OBPA 3PKKA 3PKSA 3PLIA 1XT4A 1R4UA 3WLVA 4CW0A 4XFPA 4MB8A 3PK8A 4N9SA 4N9VA 4N9MA 1XY3A 3L8WA 4R99A 2R5RA 3PKFA 4FSKA 1R51A 3PLHA 4D13A 3BK8A 5FRCA 2IC0A 4OQCA 1WS2A 3PKTA 3PK3A 3PK6A 2ZKBA 2PESA 3PLEA 1J2GA 3CKSA 2YZCA 5AYJA 3PKHA 3GKOA
chains in the Genus database with same CATH superfamily
2FXLA 2ZKAA 4PUVA 1VAXA 3PLJA 1WS3A 2ICQA 3P9FA 4D19A 4CW2A 3BJPA 4R8XA 2YZBA 2IBAA 3PK4A 2FUBA 4POEA 1WRRA 4D17A 4OP9A 4OP6A 3PLGA 3PKLA 3D2OA 1R4SA 4CW6A 1VAYA 4CW3A 4N3MA 5K95A 3PLMA 5K9GA 2YZDA 1R56A 4D12A 1XXJA 3F2MA 3CKUA 3L9GA 5LL1A 3PKGA 3P9OA 5M98A 2YZEA 4PR8A 3PKUA 3PJKA 3LBGA 3LD4A 3PK5A 3OBPA 3PKKA 3PKSA 3PLIA 1XT4A 1R4UA 3WLVA 4CW0A 4XFPA 4MB8A 3PK8A 4N9SA 4N9VA 4N9MA 1XY3A 3L8WA 4R99A 2R5RA 3PKFA 4FSKA 1R51A 3PLHA 4D13A 3BK8A 5FRCA 2IC0A 4OQCA 1WS2A 3PKTA 3PK3A 3PK6A 2ZKBA 2PESA 3PLEA 1J2GA 3CKSA 2YZCA 5AYJA 3PKHA 3GKOA
chains in the Genus database with same CATH topology
2FXLA 2ZKAA 4PUVA 1VAXA 3PLJA 1WS3A 2ICQA 3P9FA 4D19A 4CW2A 3BJPA 4R8XA 2YZBA 2IBAA 3PK4A 2FUBA 4POEA 1WRRA 4D17A 4OP9A 4OP6A 3PLGA 3PKLA 3D2OA 1R4SA 4CW6A 1VAYA 4CW3A 4N3MA 5K95A 3PLMA 5K9GA 2YZDA 1R56A 4D12A 1XXJA 3F2MA 3CKUA 3L9GA 5LL1A 3PKGA 3P9OA 5M98A 2YZEA 4PR8A 3PKUA 3PJKA 3LBGA 3LD4A 3PK5A 3OBPA 3PKKA 3PKSA 3PLIA 1XT4A 1R4UA 3WLVA 4CW0A 4XFPA 4MB8A 3PK8A 4N9SA 4N9VA 4N9MA 1XY3A 3L8WA 4R99A 2R5RA 3PKFA 4FSKA 1R51A 3PLHA 4D13A 3BK8A 5FRCA 2IC0A 4OQCA 1WS2A 3PKTA 3PK3A 3PK6A 2ZKBA 2PESA 3PLEA 1J2GA 3CKSA 2YZCA 5AYJA 3PKHA 3GKOA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2FXL A;  2ZKA A;  4PUV A;  1VAX A;  3PLJ A;  1WS3 A;  2ICQ A;  3P9F A;  4D19 A;  4CW2 A;  3BJP A;  4R8X A;  2YZB A;  2IBA A;  3PK4 A;  2FUB A;  4POE A;  1WRR A;  4D17 A;  4OP9 A;  4OP6 A;  3PLG A;  3PKL A;  3D2O A;  1R4S A;  4CW6 A;  1VAY A;  4CW3 A;  4N3M A;  5K95 A;  3PLM A;  5K9G A;  2YZD A;  1R56 A;  4D12 A;  1XXJ A;  3F2M A;  3CKU A;  3L9G A;  5LL1 A;  3PKG A;  3P9O A;  5M98 A;  2YZE A;  4PR8 A;  3PKU A;  3PJK A;  3LBG A;  3LD4 A;  3PK5 A;  3OBP A;  3PKK A;  3PKS A;  3PLI A;  1XT4 A;  1R4U A;  3WLV A;  4CW0 A;  4XFP A;  4MB8 A;  3PK8 A;  4N9S A;  4N9V A;  4N9M A;  1XY3 A;  3L8W A;  4R99 A;  2R5R A;  3PKF A;  4FSK A;  1R51 A;  3PLH A;  4D13 A;  3BK8 A;  5FRC A;  2IC0 A;  4OQC A;  1WS2 A;  3PKT A;  3PK3 A;  3PK6 A;  2ZKB A;  2PES A;  3PLE A;  1J2G A;  3CKS A;  2YZC A;  5AYJ A;  3PKH A;  3GKO A; 
#chains in the Genus database with same CATH topology
 2FXL A;  2ZKA A;  4PUV A;  1VAX A;  3PLJ A;  1WS3 A;  2ICQ A;  3P9F A;  4D19 A;  4CW2 A;  3BJP A;  4R8X A;  2YZB A;  2IBA A;  3PK4 A;  2FUB A;  4POE A;  1WRR A;  4D17 A;  4OP9 A;  4OP6 A;  3PLG A;  3PKL A;  3D2O A;  1R4S A;  4CW6 A;  1VAY A;  4CW3 A;  4N3M A;  5K95 A;  3PLM A;  5K9G A;  2YZD A;  1R56 A;  4D12 A;  1XXJ A;  3F2M A;  3CKU A;  3L9G A;  5LL1 A;  3PKG A;  3P9O A;  5M98 A;  2YZE A;  4PR8 A;  3PKU A;  3PJK A;  3LBG A;  3LD4 A;  3PK5 A;  3OBP A;  3PKK A;  3PKS A;  3PLI A;  1XT4 A;  1R4U A;  3WLV A;  4CW0 A;  4XFP A;  4MB8 A;  3PK8 A;  4N9S A;  4N9V A;  4N9M A;  1XY3 A;  3L8W A;  4R99 A;  2R5R A;  3PKF A;  4FSK A;  1R51 A;  3PLH A;  4D13 A;  3BK8 A;  5FRC A;  2IC0 A;  4OQC A;  1WS2 A;  3PKT A;  3PK3 A;  3PK6 A;  2ZKB A;  2PES A;  3PLE A;  1J2G A;  3CKS A;  2YZC A;  5AYJ A;  3PKH A;  3GKO A; 
#chains in the Genus database with same CATH homology
 2FXL A;  2ZKA A;  4PUV A;  1VAX A;  3PLJ A;  1WS3 A;  2ICQ A;  3P9F A;  4D19 A;  4CW2 A;  3BJP A;  4R8X A;  2YZB A;  2IBA A;  3PK4 A;  2FUB A;  4POE A;  1WRR A;  4D17 A;  4OP9 A;  4OP6 A;  3PLG A;  3PKL A;  3D2O A;  1R4S A;  4CW6 A;  1VAY A;  4CW3 A;  4N3M A;  5K95 A;  3PLM A;  5K9G A;  2YZD A;  1R56 A;  4D12 A;  1XXJ A;  3F2M A;  3CKU A;  3L9G A;  5LL1 A;  3PKG A;  3P9O A;  5M98 A;  2YZE A;  4PR8 A;  3PKU A;  3PJK A;  3LBG A;  3LD4 A;  3PK5 A;  3OBP A;  3PKK A;  3PKS A;  3PLI A;  1XT4 A;  1R4U A;  3WLV A;  4CW0 A;  4XFP A;  4MB8 A;  3PK8 A;  4N9S A;  4N9V A;  4N9M A;  1XY3 A;  3L8W A;  4R99 A;  2R5R A;  3PKF A;  4FSK A;  1R51 A;  3PLH A;  4D13 A;  3BK8 A;  5FRC A;  2IC0 A;  4OQC A;  1WS2 A;  3PKT A;  3PK3 A;  3PK6 A;  2ZKB A;  2PES A;  3PLE A;  1J2G A;  3CKS A;  2YZC A;  5AYJ A;  3PKH A;  3GKO A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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