4OP9A

Urate oxidase in complex with 8-azaxanthine
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
295
structure length
295
Chain Sequence
SAVKAARYGKDNVRVYKVHKDEKTGVQTVYEMTVCVLLEGEIETSYTKADNSVIVATDSIKNTIYITAKQNPVTPPELFGSILGTHFIEKYNHIHAAHVNIVCHRWTRMDIDGKPHPHSFIRDSEEKRNVQVDVVEGKGIDIKSSLSGLTVLKSTNSQFWGFLRDEYTTLKETWDRILSTDVDATWQWKNFSGLQEVRSHVPKFDATWATAREVTLKTFAEDNSASVQATMYKMAEQILARQQLIETVEYSLPNKHYFEIDLSWHKGLQNTGKNAEVFAPQSDPNGLIKCTVGRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Uricase
publication title Functinal relevance of the internal cavity of urate oxidase
rcsb
source organism Aspergillus flavus
total genus 84
structure length 295
sequence length 295
ec nomenclature ec 1.7.3.3: Factor independent urate hydroxylase.
pdb deposition date 2014-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01014 Uricase Uricase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.270.10 Alpha Beta Roll Urate Oxidase Urate Oxidase; 4op9A00
3BK8A 3PLJA 4CW0A 3L9GA 1WS3A 4D12A 5K9GA 4R99A 1XT4A 3PK3A 3PKLA 2R5RA 3PK5A 1WS2A 3PKTA 4D19A 1R4SA 3D2OA 4CW6A 5M98A 3PK4A 3LD4A 4POEA 1R51A 3WLVA 3CKSA 1R56A 2YZDA 3P9OA 1VAXA 2IC0A 3P9FA 4OQCA 2FUBA 2YZEA 4PR8A 4FSKA 1XY3A 3PLEA 4XFPA 4MB8A 1XXJA 3PJKA 4N9VA 3F2MA 4D13A 2FXLA 3PKSA 3L8WA 2YZCA 3PKKA 3PLIA 4N9MA 4D17A 5K95A 4OP9A 4CW2A 3PLMA 4N3MA 1J2GA 4R8XA 2ZKAA 3PKUA 3PLGA 5AYJA 1WRRA 2ZKBA 3PLHA 4CW3A 2ICQA 1R4UA 2PESA 3OBPA 4PUVA 1VAYA 2IBAA 4N9SA 3PK8A 3CKUA 3LBGA 3BJPA 3PKHA 3PKFA 2YZBA 3GKOA 5FRCA 3PKGA 5LL1A 4OP6A 3PK6A
chains in the Genus database with same CATH superfamily
3BK8A 3PLJA 4CW0A 3L9GA 1WS3A 4D12A 5K9GA 4R99A 1XT4A 3PK3A 3PKLA 2R5RA 3PK5A 1WS2A 3PKTA 4D19A 1R4SA 3D2OA 4CW6A 5M98A 3PK4A 3LD4A 4POEA 1R51A 3WLVA 3CKSA 1R56A 2YZDA 3P9OA 1VAXA 2IC0A 3P9FA 4OQCA 2FUBA 2YZEA 4PR8A 4FSKA 1XY3A 3PLEA 4XFPA 4MB8A 1XXJA 3PJKA 4N9VA 3F2MA 4D13A 2FXLA 3PKSA 3L8WA 2YZCA 3PKKA 3PLIA 4N9MA 4D17A 5K95A 4OP9A 4CW2A 3PLMA 4N3MA 1J2GA 4R8XA 2ZKAA 3PKUA 3PLGA 5AYJA 1WRRA 2ZKBA 3PLHA 4CW3A 2ICQA 1R4UA 2PESA 3OBPA 4PUVA 1VAYA 2IBAA 4N9SA 3PK8A 3CKUA 3LBGA 3BJPA 3PKHA 3PKFA 2YZBA 3GKOA 5FRCA 3PKGA 5LL1A 4OP6A 3PK6A
chains in the Genus database with same CATH topology
3BK8A 3PLJA 4CW0A 3L9GA 1WS3A 4D12A 5K9GA 4R99A 1XT4A 3PK3A 3PKLA 2R5RA 3PK5A 1WS2A 3PKTA 4D19A 1R4SA 3D2OA 4CW6A 5M98A 3PK4A 3LD4A 4POEA 1R51A 3WLVA 3CKSA 1R56A 2YZDA 3P9OA 1VAXA 2IC0A 3P9FA 4OQCA 2FUBA 2YZEA 4PR8A 4FSKA 1XY3A 3PLEA 4XFPA 4MB8A 1XXJA 3PJKA 4N9VA 3F2MA 4D13A 2FXLA 3PKSA 3L8WA 2YZCA 3PKKA 3PLIA 4N9MA 4D17A 5K95A 4OP9A 4CW2A 3PLMA 4N3MA 1J2GA 4R8XA 2ZKAA 3PKUA 3PLGA 5AYJA 1WRRA 2ZKBA 3PLHA 4CW3A 2ICQA 1R4UA 2PESA 3OBPA 4PUVA 1VAYA 2IBAA 4N9SA 3PK8A 3CKUA 3LBGA 3BJPA 3PKHA 3PKFA 2YZBA 3GKOA 5FRCA 3PKGA 5LL1A 4OP6A 3PK6A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3BK8 A;  3PLJ A;  4CW0 A;  3L9G A;  1WS3 A;  4D12 A;  5K9G A;  4R99 A;  1XT4 A;  3PK3 A;  3PKL A;  2R5R A;  3PK5 A;  1WS2 A;  3PKT A;  4D19 A;  1R4S A;  3D2O A;  4CW6 A;  5M98 A;  3PK4 A;  3LD4 A;  4POE A;  1R51 A;  3WLV A;  3CKS A;  1R56 A;  2YZD A;  3P9O A;  1VAX A;  2IC0 A;  3P9F A;  4OQC A;  2FUB A;  2YZE A;  4PR8 A;  4FSK A;  1XY3 A;  3PLE A;  4XFP A;  4MB8 A;  1XXJ A;  3PJK A;  4N9V A;  3F2M A;  4D13 A;  2FXL A;  3PKS A;  3L8W A;  2YZC A;  3PKK A;  3PLI A;  4N9M A;  4D17 A;  5K95 A;  4OP9 A;  4CW2 A;  3PLM A;  4N3M A;  1J2G A;  4R8X A;  2ZKA A;  3PKU A;  3PLG A;  5AYJ A;  1WRR A;  2ZKB A;  3PLH A;  4CW3 A;  2ICQ A;  1R4U A;  2PES A;  3OBP A;  4PUV A;  1VAY A;  2IBA A;  4N9S A;  3PK8 A;  3CKU A;  3LBG A;  3BJP A;  3PKH A;  3PKF A;  2YZB A;  3GKO A;  5FRC A;  3PKG A;  5LL1 A;  4OP6 A;  3PK6 A; 
#chains in the Genus database with same CATH topology
 3BK8 A;  3PLJ A;  4CW0 A;  3L9G A;  1WS3 A;  4D12 A;  5K9G A;  4R99 A;  1XT4 A;  3PK3 A;  3PKL A;  2R5R A;  3PK5 A;  1WS2 A;  3PKT A;  4D19 A;  1R4S A;  3D2O A;  4CW6 A;  5M98 A;  3PK4 A;  3LD4 A;  4POE A;  1R51 A;  3WLV A;  3CKS A;  1R56 A;  2YZD A;  3P9O A;  1VAX A;  2IC0 A;  3P9F A;  4OQC A;  2FUB A;  2YZE A;  4PR8 A;  4FSK A;  1XY3 A;  3PLE A;  4XFP A;  4MB8 A;  1XXJ A;  3PJK A;  4N9V A;  3F2M A;  4D13 A;  2FXL A;  3PKS A;  3L8W A;  2YZC A;  3PKK A;  3PLI A;  4N9M A;  4D17 A;  5K95 A;  4OP9 A;  4CW2 A;  3PLM A;  4N3M A;  1J2G A;  4R8X A;  2ZKA A;  3PKU A;  3PLG A;  5AYJ A;  1WRR A;  2ZKB A;  3PLH A;  4CW3 A;  2ICQ A;  1R4U A;  2PES A;  3OBP A;  4PUV A;  1VAY A;  2IBA A;  4N9S A;  3PK8 A;  3CKU A;  3LBG A;  3BJP A;  3PKH A;  3PKF A;  2YZB A;  3GKO A;  5FRC A;  3PKG A;  5LL1 A;  4OP6 A;  3PK6 A; 
#chains in the Genus database with same CATH homology
 3BK8 A;  3PLJ A;  4CW0 A;  3L9G A;  1WS3 A;  4D12 A;  5K9G A;  4R99 A;  1XT4 A;  3PK3 A;  3PKL A;  2R5R A;  3PK5 A;  1WS2 A;  3PKT A;  4D19 A;  1R4S A;  3D2O A;  4CW6 A;  5M98 A;  3PK4 A;  3LD4 A;  4POE A;  1R51 A;  3WLV A;  3CKS A;  1R56 A;  2YZD A;  3P9O A;  1VAX A;  2IC0 A;  3P9F A;  4OQC A;  2FUB A;  2YZE A;  4PR8 A;  4FSK A;  1XY3 A;  3PLE A;  4XFP A;  4MB8 A;  1XXJ A;  3PJK A;  4N9V A;  3F2M A;  4D13 A;  2FXL A;  3PKS A;  3L8W A;  2YZC A;  3PKK A;  3PLI A;  4N9M A;  4D17 A;  5K95 A;  4OP9 A;  4CW2 A;  3PLM A;  4N3M A;  1J2G A;  4R8X A;  2ZKA A;  3PKU A;  3PLG A;  5AYJ A;  1WRR A;  2ZKB A;  3PLH A;  4CW3 A;  2ICQ A;  1R4U A;  2PES A;  3OBP A;  4PUV A;  1VAY A;  2IBA A;  4N9S A;  3PK8 A;  3CKU A;  3LBG A;  3BJP A;  3PKH A;  3PKF A;  2YZB A;  3GKO A;  5FRC A;  3PKG A;  5LL1 A;  4OP6 A;  3PK6 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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