4OP6A

Urate oxidase + 8-azaxanthine under 40 bars oxygen
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
295
structure length
295
Chain Sequence
SAVKAARYGKDNVRVYKVHKDEKTGVQTVYEMTVCVLLEGEIETSYTKADNSVIVATDSIKNTIYITAKQNPVTPPELFGSILGTHFIEKYNHIHAAHVNIVCHRWTRMDIDGKPHPHSFIRDSEEKRNVQVDVVEGKGIDIKSSLSGLTVLKSTNSQFWGFLRDEYTTLKETWDRILSTDVDATWQWKNFSGLQEVRSHVPKFDATWATAREVTLKTFAEDNSASVQATMYKMAEQILARQQLIETVEYSLPNKHYFEIDLSWHKGLQNTGKNAEVFAPQSDPNGLIKCTVGRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Uricase
publication title Functinal relevance of the internal cavity of urate oxidase
rcsb
source organism Aspergillus flavus
total genus 83
structure length 295
sequence length 295
ec nomenclature ec 1.7.3.3: Factor independent urate hydroxylase.
pdb deposition date 2014-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01014 Uricase Uricase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.270.10 Alpha Beta Roll Urate Oxidase Urate Oxidase; 4op6A00
4D19A 2PESA 3CKSA 5M98A 2YZCA 2ICQA 3PKFA 3CKUA 4CW0A 1R4UA 3PK5A 3PKTA 5AYJA 2ZKBA 4R8XA 3PK8A 1VAYA 3PLJA 3PK6A 4CW3A 1WRRA 3LBGA 2YZEA 1R56A 3PLEA 3WLVA 3PK4A 3P9OA 2YZBA 4FSKA 3GKOA 3PKKA 2YZDA 3PLGA 1XXJA 4D17A 5K95A 4D12A 4MB8A 3F2MA 4OQCA 2R5RA 3PKGA 1XT4A 3P9FA 4XFPA 3PLHA 4CW6A 1VAXA 4OP6A 2FUBA 3OBPA 1XY3A 3PLIA 3LD4A 3PKUA 1J2GA 4N3MA 4PUVA 5K9GA 5LL1A 2IC0A 4N9VA 3PK3A 3BJPA 3PLMA 4N9SA 4PR8A 3L9GA 3PKHA 2FXLA 4R99A 4OP9A 3PJKA 3PKSA 2IBAA 3BK8A 1R4SA 1R51A 2ZKAA 5FRCA 3D2OA 4CW2A 4D13A 4N9MA 3PKLA 1WS2A 3L8WA 4POEA 1WS3A
chains in the Genus database with same CATH superfamily
4D19A 2PESA 3CKSA 5M98A 2YZCA 2ICQA 3PKFA 3CKUA 4CW0A 1R4UA 3PK5A 3PKTA 5AYJA 2ZKBA 4R8XA 3PK8A 1VAYA 3PLJA 3PK6A 4CW3A 1WRRA 3LBGA 2YZEA 1R56A 3PLEA 3WLVA 3PK4A 3P9OA 2YZBA 4FSKA 3GKOA 3PKKA 2YZDA 3PLGA 1XXJA 4D17A 5K95A 4D12A 4MB8A 3F2MA 4OQCA 2R5RA 3PKGA 1XT4A 3P9FA 4XFPA 3PLHA 4CW6A 1VAXA 4OP6A 2FUBA 3OBPA 1XY3A 3PLIA 3LD4A 3PKUA 1J2GA 4N3MA 4PUVA 5K9GA 5LL1A 2IC0A 4N9VA 3PK3A 3BJPA 3PLMA 4N9SA 4PR8A 3L9GA 3PKHA 2FXLA 4R99A 4OP9A 3PJKA 3PKSA 2IBAA 3BK8A 1R4SA 1R51A 2ZKAA 5FRCA 3D2OA 4CW2A 4D13A 4N9MA 3PKLA 1WS2A 3L8WA 4POEA 1WS3A
chains in the Genus database with same CATH topology
4D19A 2PESA 3CKSA 5M98A 2YZCA 2ICQA 3PKFA 3CKUA 4CW0A 1R4UA 3PK5A 3PKTA 5AYJA 2ZKBA 4R8XA 3PK8A 1VAYA 3PLJA 3PK6A 4CW3A 1WRRA 3LBGA 2YZEA 1R56A 3PLEA 3WLVA 3PK4A 3P9OA 2YZBA 4FSKA 3GKOA 3PKKA 2YZDA 3PLGA 1XXJA 4D17A 5K95A 4D12A 4MB8A 3F2MA 4OQCA 2R5RA 3PKGA 1XT4A 3P9FA 4XFPA 3PLHA 4CW6A 1VAXA 4OP6A 2FUBA 3OBPA 1XY3A 3PLIA 3LD4A 3PKUA 1J2GA 4N3MA 4PUVA 5K9GA 5LL1A 2IC0A 4N9VA 3PK3A 3BJPA 3PLMA 4N9SA 4PR8A 3L9GA 3PKHA 2FXLA 4R99A 4OP9A 3PJKA 3PKSA 2IBAA 3BK8A 1R4SA 1R51A 2ZKAA 5FRCA 3D2OA 4CW2A 4D13A 4N9MA 3PKLA 1WS2A 3L8WA 4POEA 1WS3A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4D19 A;  2PES A;  3CKS A;  5M98 A;  2YZC A;  2ICQ A;  3PKF A;  3CKU A;  4CW0 A;  1R4U A;  3PK5 A;  3PKT A;  5AYJ A;  2ZKB A;  4R8X A;  3PK8 A;  1VAY A;  3PLJ A;  3PK6 A;  4CW3 A;  1WRR A;  3LBG A;  2YZE A;  1R56 A;  3PLE A;  3WLV A;  3PK4 A;  3P9O A;  2YZB A;  4FSK A;  3GKO A;  3PKK A;  2YZD A;  3PLG A;  1XXJ A;  4D17 A;  5K95 A;  4D12 A;  4MB8 A;  3F2M A;  4OQC A;  2R5R A;  3PKG A;  1XT4 A;  3P9F A;  4XFP A;  3PLH A;  4CW6 A;  1VAX A;  4OP6 A;  2FUB A;  3OBP A;  1XY3 A;  3PLI A;  3LD4 A;  3PKU A;  1J2G A;  4N3M A;  4PUV A;  5K9G A;  5LL1 A;  2IC0 A;  4N9V A;  3PK3 A;  3BJP A;  3PLM A;  4N9S A;  4PR8 A;  3L9G A;  3PKH A;  2FXL A;  4R99 A;  4OP9 A;  3PJK A;  3PKS A;  2IBA A;  3BK8 A;  1R4S A;  1R51 A;  2ZKA A;  5FRC A;  3D2O A;  4CW2 A;  4D13 A;  4N9M A;  3PKL A;  1WS2 A;  3L8W A;  4POE A;  1WS3 A; 
#chains in the Genus database with same CATH topology
 4D19 A;  2PES A;  3CKS A;  5M98 A;  2YZC A;  2ICQ A;  3PKF A;  3CKU A;  4CW0 A;  1R4U A;  3PK5 A;  3PKT A;  5AYJ A;  2ZKB A;  4R8X A;  3PK8 A;  1VAY A;  3PLJ A;  3PK6 A;  4CW3 A;  1WRR A;  3LBG A;  2YZE A;  1R56 A;  3PLE A;  3WLV A;  3PK4 A;  3P9O A;  2YZB A;  4FSK A;  3GKO A;  3PKK A;  2YZD A;  3PLG A;  1XXJ A;  4D17 A;  5K95 A;  4D12 A;  4MB8 A;  3F2M A;  4OQC A;  2R5R A;  3PKG A;  1XT4 A;  3P9F A;  4XFP A;  3PLH A;  4CW6 A;  1VAX A;  4OP6 A;  2FUB A;  3OBP A;  1XY3 A;  3PLI A;  3LD4 A;  3PKU A;  1J2G A;  4N3M A;  4PUV A;  5K9G A;  5LL1 A;  2IC0 A;  4N9V A;  3PK3 A;  3BJP A;  3PLM A;  4N9S A;  4PR8 A;  3L9G A;  3PKH A;  2FXL A;  4R99 A;  4OP9 A;  3PJK A;  3PKS A;  2IBA A;  3BK8 A;  1R4S A;  1R51 A;  2ZKA A;  5FRC A;  3D2O A;  4CW2 A;  4D13 A;  4N9M A;  3PKL A;  1WS2 A;  3L8W A;  4POE A;  1WS3 A; 
#chains in the Genus database with same CATH homology
 4D19 A;  2PES A;  3CKS A;  5M98 A;  2YZC A;  2ICQ A;  3PKF A;  3CKU A;  4CW0 A;  1R4U A;  3PK5 A;  3PKT A;  5AYJ A;  2ZKB A;  4R8X A;  3PK8 A;  1VAY A;  3PLJ A;  3PK6 A;  4CW3 A;  1WRR A;  3LBG A;  2YZE A;  1R56 A;  3PLE A;  3WLV A;  3PK4 A;  3P9O A;  2YZB A;  4FSK A;  3GKO A;  3PKK A;  2YZD A;  3PLG A;  1XXJ A;  4D17 A;  5K95 A;  4D12 A;  4MB8 A;  3F2M A;  4OQC A;  2R5R A;  3PKG A;  1XT4 A;  3P9F A;  4XFP A;  3PLH A;  4CW6 A;  1VAX A;  4OP6 A;  2FUB A;  3OBP A;  1XY3 A;  3PLI A;  3LD4 A;  3PKU A;  1J2G A;  4N3M A;  4PUV A;  5K9G A;  5LL1 A;  2IC0 A;  4N9V A;  3PK3 A;  3BJP A;  3PLM A;  4N9S A;  4PR8 A;  3L9G A;  3PKH A;  2FXL A;  4R99 A;  4OP9 A;  3PJK A;  3PKS A;  2IBA A;  3BK8 A;  1R4S A;  1R51 A;  2ZKA A;  5FRC A;  3D2O A;  4CW2 A;  4D13 A;  4N9M A;  3PKL A;  1WS2 A;  3L8W A;  4POE A;  1WS3 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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