4POEA

Urate oxidase co-crystallized with uric acid and azide
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
295
structure length
295
Chain Sequence
SAVKAARYGKDNVRVYKVHKDEKTGVQTVYEMTVCVLLEGEIETSYTKADNSVIVATDSIKNTIYITAKQNPVTPPELFGSILGTHFIEKYNHIHAAHVNIVCHRWTRMDIDGKPHPHSFIRDSEEKRNVQVDVVEGKGIDIKSSLSGLTVLKSTNSQFWGFLRDEYTTLKETWDRILSTDVDATWQWKNFSGLQEVRSHVPKFDATWATAREVTLKTFAEDNSASVQATMYKMAEQILARQQLIETVEYSLPNKHYFEIDLSWHKGLQNTGKNAEVFAPQSDPNGLIKCTVGRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Oxygen binding
molecule keywords Uricase
publication title Azide inhibition of urate oxidase.
pubmed doi rcsb
source organism Aspergillus flavus
total genus 82
structure length 295
sequence length 295
ec nomenclature ec 1.7.3.3: Factor independent urate hydroxylase.
pdb deposition date 2014-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01014 Uricase Uricase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.270.10 Alpha Beta Roll Urate Oxidase Urate Oxidase; 4poeA00
1WS2A 4CW0A 4CW6A 1R51A 1WS3A 1R4UA 1J2GA 3LBGA 4MB8A 3PK4A 4OP9A 5LL1A 3GKOA 5K95A 4R99A 3CKUA 3PLMA 3PK6A 3PLGA 1WRRA 1R56A 1XT4A 4OP6A 2FXLA 3P9OA 4D17A 4R8XA 3F2MA 3PLEA 3LD4A 2R5RA 4N9VA 2IC0A 3OBPA 5M98A 5K9GA 3D2OA 5AYJA 4D19A 4OQCA 3PKFA 1XXJA 4N3MA 1R4SA 2PESA 1VAXA 2ZKAA 1VAYA 4N9SA 3PKGA 2YZEA 4POEA 4D12A 4XFPA 4PUVA 3WLVA 3PKKA 2YZDA 3PKUA 3BJPA 4N9MA 4CW3A 4PR8A 2IBAA 1XY3A 4CW2A 3L9GA 3L8WA 3PKHA 3PK5A 3PLJA 3CKSA 3PK8A 3PJKA 4D13A 3BK8A 3PK3A 3PLHA 3PKLA 3PKSA 3PKTA 3PLIA 2ZKBA 3P9FA 4FSKA 2FUBA 5FRCA 2ICQA 2YZCA 2YZBA
chains in the Genus database with same CATH superfamily
1WS2A 4CW0A 4CW6A 1R51A 1WS3A 1R4UA 1J2GA 3LBGA 4MB8A 3PK4A 4OP9A 5LL1A 3GKOA 5K95A 4R99A 3CKUA 3PLMA 3PK6A 3PLGA 1WRRA 1R56A 1XT4A 4OP6A 2FXLA 3P9OA 4D17A 4R8XA 3F2MA 3PLEA 3LD4A 2R5RA 4N9VA 2IC0A 3OBPA 5M98A 5K9GA 3D2OA 5AYJA 4D19A 4OQCA 3PKFA 1XXJA 4N3MA 1R4SA 2PESA 1VAXA 2ZKAA 1VAYA 4N9SA 3PKGA 2YZEA 4POEA 4D12A 4XFPA 4PUVA 3WLVA 3PKKA 2YZDA 3PKUA 3BJPA 4N9MA 4CW3A 4PR8A 2IBAA 1XY3A 4CW2A 3L9GA 3L8WA 3PKHA 3PK5A 3PLJA 3CKSA 3PK8A 3PJKA 4D13A 3BK8A 3PK3A 3PLHA 3PKLA 3PKSA 3PKTA 3PLIA 2ZKBA 3P9FA 4FSKA 2FUBA 5FRCA 2ICQA 2YZCA 2YZBA
chains in the Genus database with same CATH topology
1WS2A 4CW0A 4CW6A 1R51A 1WS3A 1R4UA 1J2GA 3LBGA 4MB8A 3PK4A 4OP9A 5LL1A 3GKOA 5K95A 4R99A 3CKUA 3PLMA 3PK6A 3PLGA 1WRRA 1R56A 1XT4A 4OP6A 2FXLA 3P9OA 4D17A 4R8XA 3F2MA 3PLEA 3LD4A 2R5RA 4N9VA 2IC0A 3OBPA 5M98A 5K9GA 3D2OA 5AYJA 4D19A 4OQCA 3PKFA 1XXJA 4N3MA 1R4SA 2PESA 1VAXA 2ZKAA 1VAYA 4N9SA 3PKGA 2YZEA 4POEA 4D12A 4XFPA 4PUVA 3WLVA 3PKKA 2YZDA 3PKUA 3BJPA 4N9MA 4CW3A 4PR8A 2IBAA 1XY3A 4CW2A 3L9GA 3L8WA 3PKHA 3PK5A 3PLJA 3CKSA 3PK8A 3PJKA 4D13A 3BK8A 3PK3A 3PLHA 3PKLA 3PKSA 3PKTA 3PLIA 2ZKBA 3P9FA 4FSKA 2FUBA 5FRCA 2ICQA 2YZCA 2YZBA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1WS2 A;  4CW0 A;  4CW6 A;  1R51 A;  1WS3 A;  1R4U A;  1J2G A;  3LBG A;  4MB8 A;  3PK4 A;  4OP9 A;  5LL1 A;  3GKO A;  5K95 A;  4R99 A;  3CKU A;  3PLM A;  3PK6 A;  3PLG A;  1WRR A;  1R56 A;  1XT4 A;  4OP6 A;  2FXL A;  3P9O A;  4D17 A;  4R8X A;  3F2M A;  3PLE A;  3LD4 A;  2R5R A;  4N9V A;  2IC0 A;  3OBP A;  5M98 A;  5K9G A;  3D2O A;  5AYJ A;  4D19 A;  4OQC A;  3PKF A;  1XXJ A;  4N3M A;  1R4S A;  2PES A;  1VAX A;  2ZKA A;  1VAY A;  4N9S A;  3PKG A;  2YZE A;  4POE A;  4D12 A;  4XFP A;  4PUV A;  3WLV A;  3PKK A;  2YZD A;  3PKU A;  3BJP A;  4N9M A;  4CW3 A;  4PR8 A;  2IBA A;  1XY3 A;  4CW2 A;  3L9G A;  3L8W A;  3PKH A;  3PK5 A;  3PLJ A;  3CKS A;  3PK8 A;  3PJK A;  4D13 A;  3BK8 A;  3PK3 A;  3PLH A;  3PKL A;  3PKS A;  3PKT A;  3PLI A;  2ZKB A;  3P9F A;  4FSK A;  2FUB A;  5FRC A;  2ICQ A;  2YZC A;  2YZB A; 
#chains in the Genus database with same CATH topology
 1WS2 A;  4CW0 A;  4CW6 A;  1R51 A;  1WS3 A;  1R4U A;  1J2G A;  3LBG A;  4MB8 A;  3PK4 A;  4OP9 A;  5LL1 A;  3GKO A;  5K95 A;  4R99 A;  3CKU A;  3PLM A;  3PK6 A;  3PLG A;  1WRR A;  1R56 A;  1XT4 A;  4OP6 A;  2FXL A;  3P9O A;  4D17 A;  4R8X A;  3F2M A;  3PLE A;  3LD4 A;  2R5R A;  4N9V A;  2IC0 A;  3OBP A;  5M98 A;  5K9G A;  3D2O A;  5AYJ A;  4D19 A;  4OQC A;  3PKF A;  1XXJ A;  4N3M A;  1R4S A;  2PES A;  1VAX A;  2ZKA A;  1VAY A;  4N9S A;  3PKG A;  2YZE A;  4POE A;  4D12 A;  4XFP A;  4PUV A;  3WLV A;  3PKK A;  2YZD A;  3PKU A;  3BJP A;  4N9M A;  4CW3 A;  4PR8 A;  2IBA A;  1XY3 A;  4CW2 A;  3L9G A;  3L8W A;  3PKH A;  3PK5 A;  3PLJ A;  3CKS A;  3PK8 A;  3PJK A;  4D13 A;  3BK8 A;  3PK3 A;  3PLH A;  3PKL A;  3PKS A;  3PKT A;  3PLI A;  2ZKB A;  3P9F A;  4FSK A;  2FUB A;  5FRC A;  2ICQ A;  2YZC A;  2YZB A; 
#chains in the Genus database with same CATH homology
 1WS2 A;  4CW0 A;  4CW6 A;  1R51 A;  1WS3 A;  1R4U A;  1J2G A;  3LBG A;  4MB8 A;  3PK4 A;  4OP9 A;  5LL1 A;  3GKO A;  5K95 A;  4R99 A;  3CKU A;  3PLM A;  3PK6 A;  3PLG A;  1WRR A;  1R56 A;  1XT4 A;  4OP6 A;  2FXL A;  3P9O A;  4D17 A;  4R8X A;  3F2M A;  3PLE A;  3LD4 A;  2R5R A;  4N9V A;  2IC0 A;  3OBP A;  5M98 A;  5K9G A;  3D2O A;  5AYJ A;  4D19 A;  4OQC A;  3PKF A;  1XXJ A;  4N3M A;  1R4S A;  2PES A;  1VAX A;  2ZKA A;  1VAY A;  4N9S A;  3PKG A;  2YZE A;  4POE A;  4D12 A;  4XFP A;  4PUV A;  3WLV A;  3PKK A;  2YZD A;  3PKU A;  3BJP A;  4N9M A;  4CW3 A;  4PR8 A;  2IBA A;  1XY3 A;  4CW2 A;  3L9G A;  3L8W A;  3PKH A;  3PK5 A;  3PLJ A;  3CKS A;  3PK8 A;  3PJK A;  4D13 A;  3BK8 A;  3PK3 A;  3PLH A;  3PKL A;  3PKS A;  3PKT A;  3PLI A;  2ZKB A;  3P9F A;  4FSK A;  2FUB A;  5FRC A;  2ICQ A;  2YZC A;  2YZB A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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