3L8WA

Urate oxidase from aspergillus flavus complexed with xanthin
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
295
structure length
295
Chain Sequence
SAVKAARYGKDNVRVYKVHKDEKTGVQTVYEMTVCVLLEGEIETSYTKADNSVIVATDSIKNTIYITAKQNPVTPPELFGSILGTHFIEKYNHIHAAHVNIVCHRWTRMDIDGKPHPHSFIRDSEEKRNVQVDVVEGKGIDIKSSLSGLTVLKSTNSQFWGFLRDEYTTLKETWDRILSTDVDATWQWKNFSGLQEVRSHVPKFDATWATAREVTLKTFAEDNSASVQATMYKMAEQILARQQLIETVEYSLPNKHYFEIDLSWHKGLQNTGKNAEVFAPQSDPNGLIKCTVGRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Uricase
publication title Near-atomic resolution structures of urate oxidase complexed with its substrate and analogues: the protonation state of the ligand.
pubmed doi rcsb
source organism Aspergillus flavus
total genus 74
structure length 295
sequence length 295
ec nomenclature ec 1.7.3.3: Factor independent urate hydroxylase.
pdb deposition date 2010-01-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01014 Uricase Uricase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.270.10 Alpha Beta Roll Urate Oxidase Urate Oxidase; 3l8wA00
1R51A 3PKFA 5FRCA 2FUBA 3PKLA 5AYJA 1XY3A 3PLJA 1WRRA 4N9VA 1R4UA 2ZKAA 4PUVA 3WLVA 3OBPA 3PLMA 5K95A 1R56A 4PR8A 3P9FA 3L9GA 3PK4A 2YZDA 1VAYA 4CW0A 4D13A 1XXJA 4XFPA 2FXLA 4CW3A 2YZEA 1WS3A 4FSKA 4R99A 3BJPA 4POEA 4OP9A 5M98A 1R4SA 3LBGA 5LL1A 3D2OA 2IC0A 2IBAA 4N9MA 3PLGA 3PKGA 1VAXA 3PK3A 3PKTA 3PK5A 3BK8A 3PLIA 3PKSA 3PKHA 4N3MA 3CKUA 5K9GA 2R5RA 4N9SA 3PLHA 3CKSA 2YZCA 2ZKBA 3P9OA 3GKOA 3PK8A 4OQCA 3F2MA 3PLEA 2PESA 4D12A 4MB8A 1WS2A 4R8XA 3LD4A 3L8WA 4D17A 2YZBA 4CW2A 2ICQA 4CW6A 3PKUA 3PK6A 1J2GA 1XT4A 4OP6A 4D19A 3PKKA 3PJKA
chains in the Genus database with same CATH superfamily
1R51A 3PKFA 5FRCA 2FUBA 3PKLA 5AYJA 1XY3A 3PLJA 1WRRA 4N9VA 1R4UA 2ZKAA 4PUVA 3WLVA 3OBPA 3PLMA 5K95A 1R56A 4PR8A 3P9FA 3L9GA 3PK4A 2YZDA 1VAYA 4CW0A 4D13A 1XXJA 4XFPA 2FXLA 4CW3A 2YZEA 1WS3A 4FSKA 4R99A 3BJPA 4POEA 4OP9A 5M98A 1R4SA 3LBGA 5LL1A 3D2OA 2IC0A 2IBAA 4N9MA 3PLGA 3PKGA 1VAXA 3PK3A 3PKTA 3PK5A 3BK8A 3PLIA 3PKSA 3PKHA 4N3MA 3CKUA 5K9GA 2R5RA 4N9SA 3PLHA 3CKSA 2YZCA 2ZKBA 3P9OA 3GKOA 3PK8A 4OQCA 3F2MA 3PLEA 2PESA 4D12A 4MB8A 1WS2A 4R8XA 3LD4A 3L8WA 4D17A 2YZBA 4CW2A 2ICQA 4CW6A 3PKUA 3PK6A 1J2GA 1XT4A 4OP6A 4D19A 3PKKA 3PJKA
chains in the Genus database with same CATH topology
1R51A 3PKFA 5FRCA 2FUBA 3PKLA 5AYJA 1XY3A 3PLJA 1WRRA 4N9VA 1R4UA 2ZKAA 4PUVA 3WLVA 3OBPA 3PLMA 5K95A 1R56A 4PR8A 3P9FA 3L9GA 3PK4A 2YZDA 1VAYA 4CW0A 4D13A 1XXJA 4XFPA 2FXLA 4CW3A 2YZEA 1WS3A 4FSKA 4R99A 3BJPA 4POEA 4OP9A 5M98A 1R4SA 3LBGA 5LL1A 3D2OA 2IC0A 2IBAA 4N9MA 3PLGA 3PKGA 1VAXA 3PK3A 3PKTA 3PK5A 3BK8A 3PLIA 3PKSA 3PKHA 4N3MA 3CKUA 5K9GA 2R5RA 4N9SA 3PLHA 3CKSA 2YZCA 2ZKBA 3P9OA 3GKOA 3PK8A 4OQCA 3F2MA 3PLEA 2PESA 4D12A 4MB8A 1WS2A 4R8XA 3LD4A 3L8WA 4D17A 2YZBA 4CW2A 2ICQA 4CW6A 3PKUA 3PK6A 1J2GA 1XT4A 4OP6A 4D19A 3PKKA 3PJKA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1R51 A;  3PKF A;  5FRC A;  2FUB A;  3PKL A;  5AYJ A;  1XY3 A;  3PLJ A;  1WRR A;  4N9V A;  1R4U A;  2ZKA A;  4PUV A;  3WLV A;  3OBP A;  3PLM A;  5K95 A;  1R56 A;  4PR8 A;  3P9F A;  3L9G A;  3PK4 A;  2YZD A;  1VAY A;  4CW0 A;  4D13 A;  1XXJ A;  4XFP A;  2FXL A;  4CW3 A;  2YZE A;  1WS3 A;  4FSK A;  4R99 A;  3BJP A;  4POE A;  4OP9 A;  5M98 A;  1R4S A;  3LBG A;  5LL1 A;  3D2O A;  2IC0 A;  2IBA A;  4N9M A;  3PLG A;  3PKG A;  1VAX A;  3PK3 A;  3PKT A;  3PK5 A;  3BK8 A;  3PLI A;  3PKS A;  3PKH A;  4N3M A;  3CKU A;  5K9G A;  2R5R A;  4N9S A;  3PLH A;  3CKS A;  2YZC A;  2ZKB A;  3P9O A;  3GKO A;  3PK8 A;  4OQC A;  3F2M A;  3PLE A;  2PES A;  4D12 A;  4MB8 A;  1WS2 A;  4R8X A;  3LD4 A;  3L8W A;  4D17 A;  2YZB A;  4CW2 A;  2ICQ A;  4CW6 A;  3PKU A;  3PK6 A;  1J2G A;  1XT4 A;  4OP6 A;  4D19 A;  3PKK A;  3PJK A; 
#chains in the Genus database with same CATH topology
 1R51 A;  3PKF A;  5FRC A;  2FUB A;  3PKL A;  5AYJ A;  1XY3 A;  3PLJ A;  1WRR A;  4N9V A;  1R4U A;  2ZKA A;  4PUV A;  3WLV A;  3OBP A;  3PLM A;  5K95 A;  1R56 A;  4PR8 A;  3P9F A;  3L9G A;  3PK4 A;  2YZD A;  1VAY A;  4CW0 A;  4D13 A;  1XXJ A;  4XFP A;  2FXL A;  4CW3 A;  2YZE A;  1WS3 A;  4FSK A;  4R99 A;  3BJP A;  4POE A;  4OP9 A;  5M98 A;  1R4S A;  3LBG A;  5LL1 A;  3D2O A;  2IC0 A;  2IBA A;  4N9M A;  3PLG A;  3PKG A;  1VAX A;  3PK3 A;  3PKT A;  3PK5 A;  3BK8 A;  3PLI A;  3PKS A;  3PKH A;  4N3M A;  3CKU A;  5K9G A;  2R5R A;  4N9S A;  3PLH A;  3CKS A;  2YZC A;  2ZKB A;  3P9O A;  3GKO A;  3PK8 A;  4OQC A;  3F2M A;  3PLE A;  2PES A;  4D12 A;  4MB8 A;  1WS2 A;  4R8X A;  3LD4 A;  3L8W A;  4D17 A;  2YZB A;  4CW2 A;  2ICQ A;  4CW6 A;  3PKU A;  3PK6 A;  1J2G A;  1XT4 A;  4OP6 A;  4D19 A;  3PKK A;  3PJK A; 
#chains in the Genus database with same CATH homology
 1R51 A;  3PKF A;  5FRC A;  2FUB A;  3PKL A;  5AYJ A;  1XY3 A;  3PLJ A;  1WRR A;  4N9V A;  1R4U A;  2ZKA A;  4PUV A;  3WLV A;  3OBP A;  3PLM A;  5K95 A;  1R56 A;  4PR8 A;  3P9F A;  3L9G A;  3PK4 A;  2YZD A;  1VAY A;  4CW0 A;  4D13 A;  1XXJ A;  4XFP A;  2FXL A;  4CW3 A;  2YZE A;  1WS3 A;  4FSK A;  4R99 A;  3BJP A;  4POE A;  4OP9 A;  5M98 A;  1R4S A;  3LBG A;  5LL1 A;  3D2O A;  2IC0 A;  2IBA A;  4N9M A;  3PLG A;  3PKG A;  1VAX A;  3PK3 A;  3PKT A;  3PK5 A;  3BK8 A;  3PLI A;  3PKS A;  3PKH A;  4N3M A;  3CKU A;  5K9G A;  2R5R A;  4N9S A;  3PLH A;  3CKS A;  2YZC A;  2ZKB A;  3P9O A;  3GKO A;  3PK8 A;  4OQC A;  3F2M A;  3PLE A;  2PES A;  4D12 A;  4MB8 A;  1WS2 A;  4R8X A;  3LD4 A;  3L8W A;  4D17 A;  2YZB A;  4CW2 A;  2ICQ A;  4CW6 A;  3PKU A;  3PK6 A;  1J2G A;  1XT4 A;  4OP6 A;  4D19 A;  3PKK A;  3PJK A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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