3F2MA

Urate oxidase complexed with 8-azaxanthine at 150 mpa
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
295
structure length
295
Chain Sequence
SAVKAARYGKDNVRVYKVHKDEKTGVQTVYEMTVCVLLEGEIETSYTKADNSVIVATDSIKNTIYITAKQNPVTPPELFGSILGTHFIEKYNHIHAAHVNIVCHRWTRMDIDGKPHPHSFIRDSEEKRNVQVDVVEGKGIDIKSSLSGLTVLKSTNSQFWGFLRDEYTTLKETWDRILSTDVDATWQWKNFSGLQEVRSHVPKFDATWATAREVTLKTFAEDNSASVQATMYKMAEQILARQQLIETVEYSLPNKHYFEIDLSWHKGLQNTGKNAEVFAPQSDPNGLIKCTVGRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Uricase
publication title Structure-function perturbation and dissociation of tetrameric urate oxidase by high hydrostatic pressure.
pubmed doi rcsb
source organism Aspergillus flavus
total genus 81
structure length 295
sequence length 295
ec nomenclature ec 1.7.3.3: Factor independent urate hydroxylase.
pdb deposition date 2008-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01014 Uricase Uricase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.270.10 Alpha Beta Roll Urate Oxidase Urate Oxidase; 3f2mA00
4D13A 1XXJA 4N9MA 3PLMA 3BJPA 3PK8A 1WRRA 4D12A 3WLVA 2YZBA 4D19A 4FSKA 5FRCA 3PKGA 3PKSA 4CW3A 3PKHA 1R4SA 2ZKAA 1R51A 2ZKBA 4CW2A 4XFPA 3PK5A 1VAYA 4D17A 4N9SA 3BK8A 2YZEA 3PKFA 4MB8A 3CKSA 2YZCA 3PKTA 2IC0A 1VAXA 1J2GA 2R5RA 3P9OA 2ICQA 3LBGA 3PKKA 1XY3A 3PJKA 5LL1A 1R56A 5AYJA 3PLJA 3PLGA 2FUBA 4N3MA 3PKUA 3P9FA 3PLEA 3L9GA 2FXLA 3PLHA 3PKLA 3L8WA 5K9GA 5M98A 3PK3A 3GKOA 4PUVA 4R8XA 4PR8A 3PLIA 3F2MA 5K95A 4N9VA 2YZDA 4R99A 1XT4A 3PK6A 4OP6A 3OBPA 4CW0A 1R4UA 3PK4A 4OQCA 4CW6A 1WS2A 4OP9A 1WS3A 3D2OA 2PESA 3CKUA 2IBAA 3LD4A 4POEA
chains in the Genus database with same CATH superfamily
4D13A 1XXJA 4N9MA 3PLMA 3BJPA 3PK8A 1WRRA 4D12A 3WLVA 2YZBA 4D19A 4FSKA 5FRCA 3PKGA 3PKSA 4CW3A 3PKHA 1R4SA 2ZKAA 1R51A 2ZKBA 4CW2A 4XFPA 3PK5A 1VAYA 4D17A 4N9SA 3BK8A 2YZEA 3PKFA 4MB8A 3CKSA 2YZCA 3PKTA 2IC0A 1VAXA 1J2GA 2R5RA 3P9OA 2ICQA 3LBGA 3PKKA 1XY3A 3PJKA 5LL1A 1R56A 5AYJA 3PLJA 3PLGA 2FUBA 4N3MA 3PKUA 3P9FA 3PLEA 3L9GA 2FXLA 3PLHA 3PKLA 3L8WA 5K9GA 5M98A 3PK3A 3GKOA 4PUVA 4R8XA 4PR8A 3PLIA 3F2MA 5K95A 4N9VA 2YZDA 4R99A 1XT4A 3PK6A 4OP6A 3OBPA 4CW0A 1R4UA 3PK4A 4OQCA 4CW6A 1WS2A 4OP9A 1WS3A 3D2OA 2PESA 3CKUA 2IBAA 3LD4A 4POEA
chains in the Genus database with same CATH topology
4D13A 1XXJA 4N9MA 3PLMA 3BJPA 3PK8A 1WRRA 4D12A 3WLVA 2YZBA 4D19A 4FSKA 5FRCA 3PKGA 3PKSA 4CW3A 3PKHA 1R4SA 2ZKAA 1R51A 2ZKBA 4CW2A 4XFPA 3PK5A 1VAYA 4D17A 4N9SA 3BK8A 2YZEA 3PKFA 4MB8A 3CKSA 2YZCA 3PKTA 2IC0A 1VAXA 1J2GA 2R5RA 3P9OA 2ICQA 3LBGA 3PKKA 1XY3A 3PJKA 5LL1A 1R56A 5AYJA 3PLJA 3PLGA 2FUBA 4N3MA 3PKUA 3P9FA 3PLEA 3L9GA 2FXLA 3PLHA 3PKLA 3L8WA 5K9GA 5M98A 3PK3A 3GKOA 4PUVA 4R8XA 4PR8A 3PLIA 3F2MA 5K95A 4N9VA 2YZDA 4R99A 1XT4A 3PK6A 4OP6A 3OBPA 4CW0A 1R4UA 3PK4A 4OQCA 4CW6A 1WS2A 4OP9A 1WS3A 3D2OA 2PESA 3CKUA 2IBAA 3LD4A 4POEA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4D13 A;  1XXJ A;  4N9M A;  3PLM A;  3BJP A;  3PK8 A;  1WRR A;  4D12 A;  3WLV A;  2YZB A;  4D19 A;  4FSK A;  5FRC A;  3PKG A;  3PKS A;  4CW3 A;  3PKH A;  1R4S A;  2ZKA A;  1R51 A;  2ZKB A;  4CW2 A;  4XFP A;  3PK5 A;  1VAY A;  4D17 A;  4N9S A;  3BK8 A;  2YZE A;  3PKF A;  4MB8 A;  3CKS A;  2YZC A;  3PKT A;  2IC0 A;  1VAX A;  1J2G A;  2R5R A;  3P9O A;  2ICQ A;  3LBG A;  3PKK A;  1XY3 A;  3PJK A;  5LL1 A;  1R56 A;  5AYJ A;  3PLJ A;  3PLG A;  2FUB A;  4N3M A;  3PKU A;  3P9F A;  3PLE A;  3L9G A;  2FXL A;  3PLH A;  3PKL A;  3L8W A;  5K9G A;  5M98 A;  3PK3 A;  3GKO A;  4PUV A;  4R8X A;  4PR8 A;  3PLI A;  3F2M A;  5K95 A;  4N9V A;  2YZD A;  4R99 A;  1XT4 A;  3PK6 A;  4OP6 A;  3OBP A;  4CW0 A;  1R4U A;  3PK4 A;  4OQC A;  4CW6 A;  1WS2 A;  4OP9 A;  1WS3 A;  3D2O A;  2PES A;  3CKU A;  2IBA A;  3LD4 A;  4POE A; 
#chains in the Genus database with same CATH topology
 4D13 A;  1XXJ A;  4N9M A;  3PLM A;  3BJP A;  3PK8 A;  1WRR A;  4D12 A;  3WLV A;  2YZB A;  4D19 A;  4FSK A;  5FRC A;  3PKG A;  3PKS A;  4CW3 A;  3PKH A;  1R4S A;  2ZKA A;  1R51 A;  2ZKB A;  4CW2 A;  4XFP A;  3PK5 A;  1VAY A;  4D17 A;  4N9S A;  3BK8 A;  2YZE A;  3PKF A;  4MB8 A;  3CKS A;  2YZC A;  3PKT A;  2IC0 A;  1VAX A;  1J2G A;  2R5R A;  3P9O A;  2ICQ A;  3LBG A;  3PKK A;  1XY3 A;  3PJK A;  5LL1 A;  1R56 A;  5AYJ A;  3PLJ A;  3PLG A;  2FUB A;  4N3M A;  3PKU A;  3P9F A;  3PLE A;  3L9G A;  2FXL A;  3PLH A;  3PKL A;  3L8W A;  5K9G A;  5M98 A;  3PK3 A;  3GKO A;  4PUV A;  4R8X A;  4PR8 A;  3PLI A;  3F2M A;  5K95 A;  4N9V A;  2YZD A;  4R99 A;  1XT4 A;  3PK6 A;  4OP6 A;  3OBP A;  4CW0 A;  1R4U A;  3PK4 A;  4OQC A;  4CW6 A;  1WS2 A;  4OP9 A;  1WS3 A;  3D2O A;  2PES A;  3CKU A;  2IBA A;  3LD4 A;  4POE A; 
#chains in the Genus database with same CATH homology
 4D13 A;  1XXJ A;  4N9M A;  3PLM A;  3BJP A;  3PK8 A;  1WRR A;  4D12 A;  3WLV A;  2YZB A;  4D19 A;  4FSK A;  5FRC A;  3PKG A;  3PKS A;  4CW3 A;  3PKH A;  1R4S A;  2ZKA A;  1R51 A;  2ZKB A;  4CW2 A;  4XFP A;  3PK5 A;  1VAY A;  4D17 A;  4N9S A;  3BK8 A;  2YZE A;  3PKF A;  4MB8 A;  3CKS A;  2YZC A;  3PKT A;  2IC0 A;  1VAX A;  1J2G A;  2R5R A;  3P9O A;  2ICQ A;  3LBG A;  3PKK A;  1XY3 A;  3PJK A;  5LL1 A;  1R56 A;  5AYJ A;  3PLJ A;  3PLG A;  2FUB A;  4N3M A;  3PKU A;  3P9F A;  3PLE A;  3L9G A;  2FXL A;  3PLH A;  3PKL A;  3L8W A;  5K9G A;  5M98 A;  3PK3 A;  3GKO A;  4PUV A;  4R8X A;  4PR8 A;  3PLI A;  3F2M A;  5K95 A;  4N9V A;  2YZD A;  4R99 A;  1XT4 A;  3PK6 A;  4OP6 A;  3OBP A;  4CW0 A;  1R4U A;  3PK4 A;  4OQC A;  4CW6 A;  1WS2 A;  4OP9 A;  1WS3 A;  3D2O A;  2PES A;  3CKU A;  2IBA A;  3LD4 A;  4POE A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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