2ZWEA

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 40 minutes
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
276
structure length
276
Chain Sequence
TVRKNQATLTADEKRRFVAAVLELKRSGRYDEFVRTHNEFIMSDTDSGERTGHRSPSFLPWHRRFLLDFEQALQSVDSSVTLPYWDWSADRTVRASLWAPDFLGGTGRSTDGRVMDGPFAASTGNWPINVRVDSRTYLRRSLGGSVAELPTRAEVESVLAISAYDLPPYNSASEGFRNHLEGWRGVNLHNRVHVWVGGQMATGVSPNDPVFWLHHAYVDKLWAEWQRRHPDSAYVPTGGTPDVVDLNETMKPWNTVRPADLLDHTAYYTFDALEHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
molecule keywords Tyrosinase
total genus 107
structure length 276
sequence length 276
ec nomenclature ec 1.14.18.1: Tyrosinase.
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 2zweA00
4L37A 3W6QA 3AWVA 1LLAA 4OUAA 4HD7A 4J3QA 1LL1A 2AHLA 3HHSA 2AHKA 1WX5A 2ZWEA 1WX4A 3WKYA 4J6UA 2ZWFA 4P6SA 3QJOA 1WXCA 3AWXA 2ZMYA 4J3PA 2Y9XA 4HD4A 3AWYA 4P6RA 1JS8A 1HC1A 1LNLA 3NM8A 3NQ0A 1HCYA 3WJMB 4D87A 1BUGA 3AWZA 5I3BA 4Z10A 3NQ5A 3GWJA 3NTMA 1OXYA 3W6WA 2ZWDA 3AWUA 4Z0ZA 3AWTA 3AWWA 4YZWA 4L37B 4HD6A 4OUAB 4J3RA 3HHSB 4J6VA 4P6TA 3WJMA 3NQ1A 5I3AA 1WX2A 1BT3A 3AX0A 1BT1A 2ZMXA 2ZMZA 2ZWGA 3NPYA 1BT2A 5CE9A 4J6TA 2P3XA 3AWSA 4Z0YA 1NOLA 2Y9WA 5I38A
chains in the Genus database with same CATH superfamily
4L37A 3W6QA 3AWVA 1LLAA 4OUAA 4HD7A 4J3QA 1LL1A 2AHLA 3HHSA 2AHKA 1WX5A 2ZWEA 1WX4A 3WKYA 4J6UA 2ZWFA 4P6SA 3QJOA 1WXCA 3AWXA 2ZMYA 4J3PA 2Y9XA 4HD4A 3AWYA 4P6RA 1JS8A 1HC1A 1LNLA 3NM8A 3NQ0A 1HCYA 3WJMB 4D87A 1BUGA 3AWZA 5I3BA 4Z10A 3NQ5A 3GWJA 3NTMA 1OXYA 3W6WA 2ZWDA 3AWUA 4Z0ZA 3AWTA 3AWWA 4YZWA 4L37B 4HD6A 4OUAB 4J3RA 3HHSB 4J6VA 4P6TA 3WJMA 3NQ1A 5I3AA 1WX2A 1BT3A 3AX0A 1BT1A 2ZMXA 2ZMZA 2ZWGA 3NPYA 1BT2A 5CE9A 4J6TA 2P3XA 3AWSA 4Z0YA 1NOLA 2Y9WA 5I38A
chains in the Genus database with same CATH topology
4L37A 3W6QA 3AWVA 1LLAA 4OUAA 4HD7A 4J3QA 1LL1A 2AHLA 3HHSA 2AHKA 1WX5A 2ZWEA 1WX4A 3WKYA 4J6UA 2ZWFA 4P6SA 3QJOA 1WXCA 3AWXA 2ZMYA 4J3PA 2Y9XA 4HD4A 3AWYA 4P6RA 1JS8A 1HC1A 1LNLA 3NM8A 3NQ0A 1HCYA 3WJMB 4D87A 1BUGA 3AWZA 5I3BA 4Z10A 3NQ5A 3GWJA 3NTMA 1OXYA 3W6WA 2ZWDA 3AWUA 4Z0ZA 3AWTA 3AWWA 4YZWA 4L37B 4HD6A 4OUAB 4J3RA 3HHSB 4J6VA 4P6TA 3WJMA 3NQ1A 5I3AA 1WX2A 1BT3A 3AX0A 1BT1A 2ZMXA 2ZMZA 2ZWGA 3NPYA 1BT2A 5CE9A 4J6TA 2P3XA 3AWSA 4Z0YA 1NOLA 2Y9WA 5I38A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L37 A;  3W6Q A;  3AWV A;  1LLA A;  4OUA A;  4HD7 A;  4J3Q A;  1LL1 A;  2AHL A;  3HHS A;  2AHK A;  1WX5 A;  2ZWE A;  1WX4 A;  3WKY A;  4J6U A;  2ZWF A;  4P6S A;  3QJO A;  1WXC A;  3AWX A;  2ZMY A;  4J3P A;  2Y9X A;  4HD4 A;  3AWY A;  4P6R A;  1JS8 A;  1HC1 A;  1LNL A;  3NM8 A;  3NQ0 A;  1HCY A;  3WJM B;  4D87 A;  1BUG A;  3AWZ A;  5I3B A;  4Z10 A;  3NQ5 A;  3GWJ A;  3NTM A;  1OXY A;  3W6W A;  2ZWD A;  3AWU A;  4Z0Z A;  3AWT A;  3AWW A;  4YZW A;  4L37 B;  4HD6 A;  4OUA B;  4J3R A;  3HHS B;  4J6V A;  4P6T A;  3WJM A;  3NQ1 A;  5I3A A;  1WX2 A;  1BT3 A;  3AX0 A;  1BT1 A;  2ZMX A;  2ZMZ A;  2ZWG A;  3NPY A;  1BT2 A;  5CE9 A;  4J6T A;  2P3X A;  3AWS A;  4Z0Y A;  1NOL A;  2Y9W A;  5I38 A; 
#chains in the Genus database with same CATH topology
 4L37 A;  3W6Q A;  3AWV A;  1LLA A;  4OUA A;  4HD7 A;  4J3Q A;  1LL1 A;  2AHL A;  3HHS A;  2AHK A;  1WX5 A;  2ZWE A;  1WX4 A;  3WKY A;  4J6U A;  2ZWF A;  4P6S A;  3QJO A;  1WXC A;  3AWX A;  2ZMY A;  4J3P A;  2Y9X A;  4HD4 A;  3AWY A;  4P6R A;  1JS8 A;  1HC1 A;  1LNL A;  3NM8 A;  3NQ0 A;  1HCY A;  3WJM B;  4D87 A;  1BUG A;  3AWZ A;  5I3B A;  4Z10 A;  3NQ5 A;  3GWJ A;  3NTM A;  1OXY A;  3W6W A;  2ZWD A;  3AWU A;  4Z0Z A;  3AWT A;  3AWW A;  4YZW A;  4L37 B;  4HD6 A;  4OUA B;  4J3R A;  3HHS B;  4J6V A;  4P6T A;  3WJM A;  3NQ1 A;  5I3A A;  1WX2 A;  1BT3 A;  3AX0 A;  1BT1 A;  2ZMX A;  2ZMZ A;  2ZWG A;  3NPY A;  1BT2 A;  5CE9 A;  4J6T A;  2P3X A;  3AWS A;  4Z0Y A;  1NOL A;  2Y9W A;  5I38 A; 
#chains in the Genus database with same CATH homology
 4L37 A;  3W6Q A;  3AWV A;  1LLA A;  4OUA A;  4HD7 A;  4J3Q A;  1LL1 A;  2AHL A;  3HHS A;  2AHK A;  1WX5 A;  2ZWE A;  1WX4 A;  3WKY A;  4J6U A;  2ZWF A;  4P6S A;  3QJO A;  1WXC A;  3AWX A;  2ZMY A;  4J3P A;  2Y9X A;  4HD4 A;  3AWY A;  4P6R A;  1JS8 A;  1HC1 A;  1LNL A;  3NM8 A;  3NQ0 A;  1HCY A;  3WJM B;  4D87 A;  1BUG A;  3AWZ A;  5I3B A;  4Z10 A;  3NQ5 A;  3GWJ A;  3NTM A;  1OXY A;  3W6W A;  2ZWD A;  3AWU A;  4Z0Z A;  3AWT A;  3AWW A;  4YZW A;  4L37 B;  4HD6 A;  4OUA B;  4J3R A;  3HHS B;  4J6V A;  4P6T A;  3WJM A;  3NQ1 A;  5I3A A;  1WX2 A;  1BT3 A;  3AX0 A;  1BT1 A;  2ZMX A;  2ZMZ A;  2ZWG A;  3NPY A;  1BT2 A;  5CE9 A;  4J6T A;  2P3X A;  3AWS A;  4Z0Y A;  1NOL A;  2Y9W A;  5I38 A; 
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