3AWUA

Crystal structure of streptomyces tyrosinase in a complex with caddie soaked in a cu(ii)-containing solution for 40 h
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
278
structure length
278
Chain Sequence
TVRKNQATLTADEKRRFVAAVLELKRSGRYDEFVRTHNEFIMSDTDSGERTGHRSPSFLPWHRRFLLDFEQALQSVDSSVTLPYWDWSADRTVRASLWAPDFLGGTGRSTDGRVMDGPFAASTGNWPINVRVDSRTYLRRSLGGSVAELPTRAEVESVLAISAYDLPPYNSASEGFRNHLEGWRGVNLHNRVHVWVGGQMATGVSPNDPVFWLHHAYVDKLWAEWQRRHPDSAYVPTGGTPDVVDLNETMKPWNTVRPADLLDHTAYYTFDALEHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A molecular mechanism for copper transportation to tyrosinase that is assisted by a metallochaperone, caddie protein
pubmed doi rcsb
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
molecule keywords Tyrosinase
total genus 103
structure length 278
sequence length 278
ec nomenclature ec 1.14.18.1: Tyrosinase.
pdb deposition date 2011-03-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 3awuA00
4L37B 1LLAA 1WX2A 5I3AA 3AWUA 2ZWDA 4P6RA 3QJOA 1WX5A 3NQ5A 3AWSA 1BUGA 1WX4A 2ZMYA 3WJMA 3NQ0A 2ZMZA 4J6UA 5I3BA 3AX0A 3AWVA 1OXYA 4J6TA 3NQ1A 1NOLA 4Z10A 3AWZA 3GWJA 4J3RA 4HD6A 4J6VA 1BT2A 4HD4A 1BT1A 3HHSA 4Z0ZA 2ZWEA 3WJMB 4HD7A 2AHKA 3NTMA 3NPYA 4J3PA 1WXCA 1LL1A 4D87A 3NM8A 1BT3A 2ZMXA 3HHSB 1HCYA 4YZWA 2ZWGA 4P6TA 3W6QA 4P6SA 2ZWFA 5CE9A 3AWXA 1LNLA 4L37A 2AHLA 3W6WA 3WKYA 5I38A 3AWTA 3AWYA 4OUAB 2Y9WA 4Z0YA 4OUAA 1HC1A 1JS8A 4J3QA 2P3XA 3AWWA 2Y9XA
chains in the Genus database with same CATH superfamily
4L37B 1LLAA 1WX2A 5I3AA 3AWUA 2ZWDA 4P6RA 3QJOA 1WX5A 3NQ5A 3AWSA 1BUGA 1WX4A 2ZMYA 3WJMA 3NQ0A 2ZMZA 4J6UA 5I3BA 3AX0A 3AWVA 1OXYA 4J6TA 3NQ1A 1NOLA 4Z10A 3AWZA 3GWJA 4J3RA 4HD6A 4J6VA 1BT2A 4HD4A 1BT1A 3HHSA 4Z0ZA 2ZWEA 3WJMB 4HD7A 2AHKA 3NTMA 3NPYA 4J3PA 1WXCA 1LL1A 4D87A 3NM8A 1BT3A 2ZMXA 3HHSB 1HCYA 4YZWA 2ZWGA 4P6TA 3W6QA 4P6SA 2ZWFA 5CE9A 3AWXA 1LNLA 4L37A 2AHLA 3W6WA 3WKYA 5I38A 3AWTA 3AWYA 4OUAB 2Y9WA 4Z0YA 4OUAA 1HC1A 1JS8A 4J3QA 2P3XA 3AWWA 2Y9XA
chains in the Genus database with same CATH topology
4L37B 1LLAA 1WX2A 5I3AA 3AWUA 2ZWDA 4P6RA 3QJOA 1WX5A 3NQ5A 3AWSA 1BUGA 1WX4A 2ZMYA 3WJMA 3NQ0A 2ZMZA 4J6UA 5I3BA 3AX0A 3AWVA 1OXYA 4J6TA 3NQ1A 1NOLA 4Z10A 3AWZA 3GWJA 4J3RA 4HD6A 4J6VA 1BT2A 4HD4A 1BT1A 3HHSA 4Z0ZA 2ZWEA 3WJMB 4HD7A 2AHKA 3NTMA 3NPYA 4J3PA 1WXCA 1LL1A 4D87A 3NM8A 1BT3A 2ZMXA 3HHSB 1HCYA 4YZWA 2ZWGA 4P6TA 3W6QA 4P6SA 2ZWFA 5CE9A 3AWXA 1LNLA 4L37A 2AHLA 3W6WA 3WKYA 5I38A 3AWTA 3AWYA 4OUAB 2Y9WA 4Z0YA 4OUAA 1HC1A 1JS8A 4J3QA 2P3XA 3AWWA 2Y9XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L37 B;  1LLA A;  1WX2 A;  5I3A A;  3AWU A;  2ZWD A;  4P6R A;  3QJO A;  1WX5 A;  3NQ5 A;  3AWS A;  1BUG A;  1WX4 A;  2ZMY A;  3WJM A;  3NQ0 A;  2ZMZ A;  4J6U A;  5I3B A;  3AX0 A;  3AWV A;  1OXY A;  4J6T A;  3NQ1 A;  1NOL A;  4Z10 A;  3AWZ A;  3GWJ A;  4J3R A;  4HD6 A;  4J6V A;  1BT2 A;  4HD4 A;  1BT1 A;  3HHS A;  4Z0Z A;  2ZWE A;  3WJM B;  4HD7 A;  2AHK A;  3NTM A;  3NPY A;  4J3P A;  1WXC A;  1LL1 A;  4D87 A;  3NM8 A;  1BT3 A;  2ZMX A;  3HHS B;  1HCY A;  4YZW A;  2ZWG A;  4P6T A;  3W6Q A;  4P6S A;  2ZWF A;  5CE9 A;  3AWX A;  1LNL A;  4L37 A;  2AHL A;  3W6W A;  3WKY A;  5I38 A;  3AWT A;  3AWY A;  4OUA B;  2Y9W A;  4Z0Y A;  4OUA A;  1HC1 A;  1JS8 A;  4J3Q A;  2P3X A;  3AWW A;  2Y9X A; 
#chains in the Genus database with same CATH topology
 4L37 B;  1LLA A;  1WX2 A;  5I3A A;  3AWU A;  2ZWD A;  4P6R A;  3QJO A;  1WX5 A;  3NQ5 A;  3AWS A;  1BUG A;  1WX4 A;  2ZMY A;  3WJM A;  3NQ0 A;  2ZMZ A;  4J6U A;  5I3B A;  3AX0 A;  3AWV A;  1OXY A;  4J6T A;  3NQ1 A;  1NOL A;  4Z10 A;  3AWZ A;  3GWJ A;  4J3R A;  4HD6 A;  4J6V A;  1BT2 A;  4HD4 A;  1BT1 A;  3HHS A;  4Z0Z A;  2ZWE A;  3WJM B;  4HD7 A;  2AHK A;  3NTM A;  3NPY A;  4J3P A;  1WXC A;  1LL1 A;  4D87 A;  3NM8 A;  1BT3 A;  2ZMX A;  3HHS B;  1HCY A;  4YZW A;  2ZWG A;  4P6T A;  3W6Q A;  4P6S A;  2ZWF A;  5CE9 A;  3AWX A;  1LNL A;  4L37 A;  2AHL A;  3W6W A;  3WKY A;  5I38 A;  3AWT A;  3AWY A;  4OUA B;  2Y9W A;  4Z0Y A;  4OUA A;  1HC1 A;  1JS8 A;  4J3Q A;  2P3X A;  3AWW A;  2Y9X A; 
#chains in the Genus database with same CATH homology
 4L37 B;  1LLA A;  1WX2 A;  5I3A A;  3AWU A;  2ZWD A;  4P6R A;  3QJO A;  1WX5 A;  3NQ5 A;  3AWS A;  1BUG A;  1WX4 A;  2ZMY A;  3WJM A;  3NQ0 A;  2ZMZ A;  4J6U A;  5I3B A;  3AX0 A;  3AWV A;  1OXY A;  4J6T A;  3NQ1 A;  1NOL A;  4Z10 A;  3AWZ A;  3GWJ A;  4J3R A;  4HD6 A;  4J6V A;  1BT2 A;  4HD4 A;  1BT1 A;  3HHS A;  4Z0Z A;  2ZWE A;  3WJM B;  4HD7 A;  2AHK A;  3NTM A;  3NPY A;  4J3P A;  1WXC A;  1LL1 A;  4D87 A;  3NM8 A;  1BT3 A;  2ZMX A;  3HHS B;  1HCY A;  4YZW A;  2ZWG A;  4P6T A;  3W6Q A;  4P6S A;  2ZWF A;  5CE9 A;  3AWX A;  1LNL A;  4L37 A;  2AHL A;  3W6W A;  3WKY A;  5I38 A;  3AWT A;  3AWY A;  4OUA B;  2Y9W A;  4Z0Y A;  4OUA A;  1HC1 A;  1JS8 A;  4J3Q A;  2P3X A;  3AWW A;  2Y9X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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