3AWWA

Crystal structure of streptomyces tyrosinase in a complex with caddie soaked in a cu(ii)-containing solution for 80 hr: occupancy of cua is high
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
278
structure length
278
Chain Sequence
TVRKNQATLTADEKRRFVAAVLELKRSGRYDEFVRTHNEFIMSDTDSGERTGHRSPSFLPWHRRFLLDFEQALQSVDSSVTLPYWDWSADRTVRASLWAPDFLGGTGRSTDGRVMDGPFAASTGNWPINVRVDSRTYLRRSLGGSVAELPTRAEVESVLAISAYDLPPYNSASEGFRNHLEGWRGVNLHNRVHVWVGGQMATGVSPNDPVFWLHHAYVDKLWAEWQRRHPDSAYVPTGGTPDVVDLNETMKPWNTVRPADLLDHTAYYTFDALEHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A molecular mechanism for copper transportation to tyrosinase that is assisted by a metallochaperone, caddie protein
pubmed doi rcsb
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
molecule keywords Tyrosinase
total genus 107
structure length 278
sequence length 278
ec nomenclature ec 1.14.18.1: Tyrosinase.
pdb deposition date 2011-03-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 3awwA00
2ZMYA 3WJMB 1WX4A 2ZMZA 1BT3A 1LLAA 5I3BA 4L37A 5I3AA 4L37B 2P3XA 4J3QA 1LL1A 1JS8A 4P6RA 2ZMXA 5CE9A 3QJOA 5I38A 3HHSB 4HD7A 3W6WA 3WJMA 3AWSA 4J3RA 2AHLA 1BT2A 3NPYA 4HD4A 4D87A 2ZWFA 3AWVA 4J6VA 2ZWEA 1BUGA 2ZWDA 3AWYA 1WXCA 4YZWA 4J3PA 2ZWGA 3AX0A 1LNLA 3HHSA 3NM8A 3AWZA 3WKYA 4J6UA 4P6TA 4Z10A 4Z0YA 1BT1A 3AWXA 2Y9WA 2AHKA 1WX2A 4J6TA 4HD6A 3W6QA 1OXYA 3AWUA 3AWWA 4P6SA 4OUAA 4OUAB 3NQ0A 1WX5A 3NTMA 3NQ5A 3GWJA 1HCYA 3NQ1A 1NOLA 2Y9XA 4Z0ZA 1HC1A 3AWTA
chains in the Genus database with same CATH superfamily
2ZMYA 3WJMB 1WX4A 2ZMZA 1BT3A 1LLAA 5I3BA 4L37A 5I3AA 4L37B 2P3XA 4J3QA 1LL1A 1JS8A 4P6RA 2ZMXA 5CE9A 3QJOA 5I38A 3HHSB 4HD7A 3W6WA 3WJMA 3AWSA 4J3RA 2AHLA 1BT2A 3NPYA 4HD4A 4D87A 2ZWFA 3AWVA 4J6VA 2ZWEA 1BUGA 2ZWDA 3AWYA 1WXCA 4YZWA 4J3PA 2ZWGA 3AX0A 1LNLA 3HHSA 3NM8A 3AWZA 3WKYA 4J6UA 4P6TA 4Z10A 4Z0YA 1BT1A 3AWXA 2Y9WA 2AHKA 1WX2A 4J6TA 4HD6A 3W6QA 1OXYA 3AWUA 3AWWA 4P6SA 4OUAA 4OUAB 3NQ0A 1WX5A 3NTMA 3NQ5A 3GWJA 1HCYA 3NQ1A 1NOLA 2Y9XA 4Z0ZA 1HC1A 3AWTA
chains in the Genus database with same CATH topology
2ZMYA 3WJMB 1WX4A 2ZMZA 1BT3A 1LLAA 5I3BA 4L37A 5I3AA 4L37B 2P3XA 4J3QA 1LL1A 1JS8A 4P6RA 2ZMXA 5CE9A 3QJOA 5I38A 3HHSB 4HD7A 3W6WA 3WJMA 3AWSA 4J3RA 2AHLA 1BT2A 3NPYA 4HD4A 4D87A 2ZWFA 3AWVA 4J6VA 2ZWEA 1BUGA 2ZWDA 3AWYA 1WXCA 4YZWA 4J3PA 2ZWGA 3AX0A 1LNLA 3HHSA 3NM8A 3AWZA 3WKYA 4J6UA 4P6TA 4Z10A 4Z0YA 1BT1A 3AWXA 2Y9WA 2AHKA 1WX2A 4J6TA 4HD6A 3W6QA 1OXYA 3AWUA 3AWWA 4P6SA 4OUAA 4OUAB 3NQ0A 1WX5A 3NTMA 3NQ5A 3GWJA 1HCYA 3NQ1A 1NOLA 2Y9XA 4Z0ZA 1HC1A 3AWTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZMY A;  3WJM B;  1WX4 A;  2ZMZ A;  1BT3 A;  1LLA A;  5I3B A;  4L37 A;  5I3A A;  4L37 B;  2P3X A;  4J3Q A;  1LL1 A;  1JS8 A;  4P6R A;  2ZMX A;  5CE9 A;  3QJO A;  5I38 A;  3HHS B;  4HD7 A;  3W6W A;  3WJM A;  3AWS A;  4J3R A;  2AHL A;  1BT2 A;  3NPY A;  4HD4 A;  4D87 A;  2ZWF A;  3AWV A;  4J6V A;  2ZWE A;  1BUG A;  2ZWD A;  3AWY A;  1WXC A;  4YZW A;  4J3P A;  2ZWG A;  3AX0 A;  1LNL A;  3HHS A;  3NM8 A;  3AWZ A;  3WKY A;  4J6U A;  4P6T A;  4Z10 A;  4Z0Y A;  1BT1 A;  3AWX A;  2Y9W A;  2AHK A;  1WX2 A;  4J6T A;  4HD6 A;  3W6Q A;  1OXY A;  3AWU A;  3AWW A;  4P6S A;  4OUA A;  4OUA B;  3NQ0 A;  1WX5 A;  3NTM A;  3NQ5 A;  3GWJ A;  1HCY A;  3NQ1 A;  1NOL A;  2Y9X A;  4Z0Z A;  1HC1 A;  3AWT A; 
#chains in the Genus database with same CATH topology
 2ZMY A;  3WJM B;  1WX4 A;  2ZMZ A;  1BT3 A;  1LLA A;  5I3B A;  4L37 A;  5I3A A;  4L37 B;  2P3X A;  4J3Q A;  1LL1 A;  1JS8 A;  4P6R A;  2ZMX A;  5CE9 A;  3QJO A;  5I38 A;  3HHS B;  4HD7 A;  3W6W A;  3WJM A;  3AWS A;  4J3R A;  2AHL A;  1BT2 A;  3NPY A;  4HD4 A;  4D87 A;  2ZWF A;  3AWV A;  4J6V A;  2ZWE A;  1BUG A;  2ZWD A;  3AWY A;  1WXC A;  4YZW A;  4J3P A;  2ZWG A;  3AX0 A;  1LNL A;  3HHS A;  3NM8 A;  3AWZ A;  3WKY A;  4J6U A;  4P6T A;  4Z10 A;  4Z0Y A;  1BT1 A;  3AWX A;  2Y9W A;  2AHK A;  1WX2 A;  4J6T A;  4HD6 A;  3W6Q A;  1OXY A;  3AWU A;  3AWW A;  4P6S A;  4OUA A;  4OUA B;  3NQ0 A;  1WX5 A;  3NTM A;  3NQ5 A;  3GWJ A;  1HCY A;  3NQ1 A;  1NOL A;  2Y9X A;  4Z0Z A;  1HC1 A;  3AWT A; 
#chains in the Genus database with same CATH homology
 2ZMY A;  3WJM B;  1WX4 A;  2ZMZ A;  1BT3 A;  1LLA A;  5I3B A;  4L37 A;  5I3A A;  4L37 B;  2P3X A;  4J3Q A;  1LL1 A;  1JS8 A;  4P6R A;  2ZMX A;  5CE9 A;  3QJO A;  5I38 A;  3HHS B;  4HD7 A;  3W6W A;  3WJM A;  3AWS A;  4J3R A;  2AHL A;  1BT2 A;  3NPY A;  4HD4 A;  4D87 A;  2ZWF A;  3AWV A;  4J6V A;  2ZWE A;  1BUG A;  2ZWD A;  3AWY A;  1WXC A;  4YZW A;  4J3P A;  2ZWG A;  3AX0 A;  1LNL A;  3HHS A;  3NM8 A;  3AWZ A;  3WKY A;  4J6U A;  4P6T A;  4Z10 A;  4Z0Y A;  1BT1 A;  3AWX A;  2Y9W A;  2AHK A;  1WX2 A;  4J6T A;  4HD6 A;  3W6Q A;  1OXY A;  3AWU A;  3AWW A;  4P6S A;  4OUA A;  4OUA B;  3NQ0 A;  1WX5 A;  3NTM A;  3NQ5 A;  3GWJ A;  1HCY A;  3NQ1 A;  1NOL A;  2Y9X A;  4Z0Z A;  1HC1 A;  3AWT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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