3CC4U

Co-crystal structure of anisomycin bound to the 50s ribosomal subunit
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 10
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2008-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
U PF01246 Ribosomal_L24e Ribosomal protein L24e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3cc4U00
1KD1V 1JJ2T 2QEXU 3I55U 2QA4U 1YIJU 1VQNU 1M90V 3CMEU 3CCQU 3CD6U 3CCSU 3G6EU 1Q82V 1KC8V 1YJNU 3CXCT 1VQ4U 3CC7U 1Q86V 1K73V 1W2BT 2OTJU 1K8AV 2OTLU 1VQ7U 3G71U 1VQPU 3G4SU 3CCMU 3CCUU 1VQKU 1QVGT 5AN9G 1NJIV 1YI2U 1VQ6U 1YJ9U 1YHQU 1YITU 3CCLU 1S72U 3CMAU 1VQOU 1M1KV 1K9MV 1N8RV 1VQ5U 3CCEU 1VQLU 1VQ9U 3CCVU 3CCJU 1KQST 1VQ8U 3CC4U 3CCRU 1Q81V 3CC2U 1YJWU 3OW2T 1VQMU 1Q7YV 3I56U 1QVFT 3CPWT
chains in the Genus database with same CATH superfamily
2QEXU 1VQNU 2QA4U 5MLCY 3ABOA 1W2BT 3ABSA 3AO0A 1QVGT 1YJ9U 1YHQU 3CCLU 1S72U 1VQ5U 3CCEU 3CC4U 3CCRU 3OW2T 1VQMU 3I56U 3CPWT 1KD1V 3I55U 1M90V 3CCQU 3CD6U 3CCSU 3G6EU 1Q82V 1VQ4U 3CC7U 1JJDA 1K73V 1VQ7U 5DM6U 3CCMU 1VQOU 1M1KV 1K9MV 1N8RV 1VQLU 1VQ9U 3CCVU 2JZ6A 1Q7YV 3ANYA 1JJ2T 1KC8V 1YJNU 1Q86V 2OTJU 2OTLU 1VQPU 3CCUU 3CMAU 1KQST 1VQ8U 2QEZA 3J7ZX 1Q81V 1VQ6U 1QVFT 3ABRA 1YIJU 3CMEU 3CXCT 5H1SY 1K8AV 3G71U 3G4SU 1VQKU 5AN9G 1NJIV 1YI2U 3ABQA 3CCJU 3CC2U 1YJWU 1YITU 4UY8X
chains in the Genus database with same CATH topology
1KD1V 1JJ2T 2QEXU 3I55U 2QA4U 1YIJU 1VQNU 1M90V 3CMEU 3CCQU 3CD6U 3CCSU 3G6EU 1Q82V 1KC8V 1YJNU 3CXCT 1VQ4U 3CC7U 1JJDA 1Q86V 1W2BT 1K73V 2OTJU 1K8AV 2OTLU 1VQ7U 3G71U 1VQPU 3G4SU 3CCMU 3CCUU 1VQKU 1QVGT 5AN9G 1NJIV 1YI2U 1VQ6U 1YJ9U 1YHQU 1YITU 3CCLU 1S72U 3CMAU 1VQOU 1M1KV 1K9MV 1N8RV 1VQ5U 3CCEU 1VQLU 1VQ9U 3CCVU 3CCJU 1KQST 1VQ8U 3CC4U 3CCRU 1Q81V 3CC2U 1YJWU 3OW2T 1VQMU 1Q7YV 3I56U 1QVFT 3CPWT
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KD1 V;  1JJ2 T;  2QEX U;  3I55 U;  2QA4 U;  1YIJ U;  1VQN U;  1M90 V;  3CME U;  3CCQ U;  3CD6 U;  3CCS U;  3G6E U;  1Q82 V;  1KC8 V;  1YJN U;  3CXC T;  1VQ4 U;  3CC7 U;  1Q86 V;  1K73 V;  1W2B T;  2OTJ U;  1K8A V;  2OTL U;  1VQ7 U;  3G71 U;  1VQP U;  3G4S U;  3CCM U;  3CCU U;  1VQK U;  1QVG T;  5AN9 G;  1NJI V;  1YI2 U;  1VQ6 U;  1YJ9 U;  1YHQ U;  1YIT U;  3CCL U;  1S72 U;  3CMA U;  1VQO U;  1M1K V;  1K9M V;  1N8R V;  1VQ5 U;  3CCE U;  1VQL U;  1VQ9 U;  3CCV U;  3CCJ U;  1KQS T;  1VQ8 U;  3CC4 U;  3CCR U;  1Q81 V;  3CC2 U;  1YJW U;  3OW2 T;  1VQM U;  1Q7Y V;  3I56 U;  1QVF T;  3CPW T; 
#chains in the Genus database with same CATH topology
 2QEX U;  1VQN U;  2QA4 U;  5MLC Y;  3ABO A;  1W2B T;  3ABS A;  3AO0 A;  1QVG T;  1YJ9 U;  1YHQ U;  3CCL U;  1S72 U;  1VQ5 U;  3CCE U;  3CC4 U;  3CCR U;  3OW2 T;  1VQM U;  3I56 U;  3CPW T;  1KD1 V;  3I55 U;  1M90 V;  3CCQ U;  3CD6 U;  3CCS U;  3G6E U;  1Q82 V;  1VQ4 U;  3CC7 U;  1JJD A;  1K73 V;  1VQ7 U;  5DM6 U;  3CCM U;  1VQO U;  1M1K V;  1K9M V;  1N8R V;  1VQL U;  1VQ9 U;  3CCV U;  2JZ6 A;  1Q7Y V;  3ANY A;  1JJ2 T;  1KC8 V;  1YJN U;  1Q86 V;  2OTJ U;  2OTL U;  1VQP U;  3CCU U;  3CMA U;  1KQS T;  1VQ8 U;  2QEZ A;  3J7Z X;  1Q81 V;  1VQ6 U;  1QVF T;  3ABR A;  1YIJ U;  3CME U;  3CXC T;  5H1S Y;  1K8A V;  3G71 U;  3G4S U;  1VQK U;  5AN9 G;  1NJI V;  1YI2 U;  3ABQ A;  3CCJ U;  3CC2 U;  1YJW U;  1YIT U;  4UY8 X; 
#chains in the Genus database with same CATH homology
 1KD1 V;  1JJ2 T;  2QEX U;  3I55 U;  2QA4 U;  1YIJ U;  1VQN U;  1M90 V;  3CME U;  3CCQ U;  3CD6 U;  3CCS U;  3G6E U;  1Q82 V;  1KC8 V;  1YJN U;  3CXC T;  1VQ4 U;  3CC7 U;  1JJD A;  1Q86 V;  1W2B T;  1K73 V;  2OTJ U;  1K8A V;  2OTL U;  1VQ7 U;  3G71 U;  1VQP U;  3G4S U;  3CCM U;  3CCU U;  1VQK U;  1QVG T;  5AN9 G;  1NJI V;  1YI2 U;  1VQ6 U;  1YJ9 U;  1YHQ U;  1YIT U;  3CCL U;  1S72 U;  3CMA U;  1VQO U;  1M1K V;  1K9M V;  1N8R V;  1VQ5 U;  3CCE U;  1VQL U;  1VQ9 U;  3CCV U;  3CCJ U;  1KQS T;  1VQ8 U;  3CC4 U;  3CCR U;  1Q81 V;  3CC2 U;  1YJW U;  3OW2 T;  1VQM U;  1Q7Y V;  3I56 U;  1QVF T;  3CPW T; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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