3CCLU

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule keywords 50S ribosomal protein L2P
molecule tags Ribosome
total genus 12
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
U PF01246 Ribosomal_L24e Ribosomal protein L24e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3cclU00
2OTLU 1JJ2T 3G4SU 3CCQU 1VQ7U 1KC8V 1K73V 1YITU 3CXCT 1VQPU 1VQOU 1VQ4U 3CCJU 1VQNU 1YJ9U 3CD6U 3CCMU 1KD1V 1VQ8U 1VQMU 3CCEU 1VQ9U 3OW2T 3CPWT 1KQST 1W2BT 1N8RV 3CC2U 1QVFT 2QEXU 1Q82V 1Q86V 1VQ6U 3CCLU 1S72U 3CCRU 1YI2U 1Q81V 1VQ5U 1M90V 1M1KV 3CMAU 1VQLU 1NJIV 3CCVU 1YJNU 3CC7U 1K8AV 1K9MV 3CCSU 2QA4U 3I55U 1VQKU 3CCUU 3G71U 5AN9G 3CC4U 1YIJU 3G6EU 3I56U 1YJWU 1QVGT 2OTJU 1Q7YV 3CMEU 1YHQU
chains in the Genus database with same CATH superfamily
1VQNU 1YJ9U 5MLCY 3ANYA 1VQ9U 3ABRA 1W2BT 1QVFT 3CCRU 1JJDA 1VQLU 4UY8X 1YJNU 3CCSU 3I55U 3ABQA 3G6EU 2OTJU 1Q7YV 1KC8V 1YITU 1VQPU 3CD6U 1VQMU 3CPWT 1VQ6U 3CCLU 1S72U 1YI2U 1Q81V 1VQ5U 1M1KV 3ABOA 2QA4U 1VQKU 3ABSA 2QEZA 3G4SU 1VQ7U 3J7ZX 1VQ4U 3AO0A 3CCJU 3CCMU 3OW2T 1N8RV 1Q82V 1Q86V 1M90V 3CC7U 2JZ6A 1K8AV 1YIJU 1YJWU 1QVGT 2OTLU 1JJ2T 3CCQU 1K73V 3CXCT 1VQOU 5DM6U 1KD1V 1VQ8U 3CCEU 5H1SY 1KQST 3CC2U 2QEXU 3CMAU 1NJIV 3CCVU 1K9MV 3CCUU 3G71U 5AN9G 3CC4U 3I56U 3CMEU 1YHQU
chains in the Genus database with same CATH topology
2OTLU 1JJ2T 3G4SU 3CCQU 1VQ7U 1KC8V 1K73V 1YITU 3CXCT 1VQPU 1VQOU 1VQ4U 3CCJU 1VQNU 1YJ9U 3CD6U 3CCMU 1KD1V 1VQ8U 1VQMU 3CCEU 1VQ9U 3OW2T 3CPWT 1KQST 1W2BT 1N8RV 3CC2U 1QVFT 2QEXU 1Q82V 1Q86V 1VQ6U 3CCLU 1S72U 3CCRU 1JJDA 1YI2U 1Q81V 1VQ5U 1M90V 1M1KV 3CMAU 1VQLU 1NJIV 3CCVU 1YJNU 3CC7U 1K8AV 1K9MV 3CCSU 2QA4U 3I55U 1VQKU 3CCUU 3G71U 5AN9G 3CC4U 1YIJU 3G6EU 3I56U 1YJWU 1QVGT 2OTJU 1Q7YV 3CMEU 1YHQU
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OTL U;  1JJ2 T;  3G4S U;  3CCQ U;  1VQ7 U;  1KC8 V;  1K73 V;  1YIT U;  3CXC T;  1VQP U;  1VQO U;  1VQ4 U;  3CCJ U;  1VQN U;  1YJ9 U;  3CD6 U;  3CCM U;  1KD1 V;  1VQ8 U;  1VQM U;  3CCE U;  1VQ9 U;  3OW2 T;  3CPW T;  1KQS T;  1W2B T;  1N8R V;  3CC2 U;  1QVF T;  2QEX U;  1Q82 V;  1Q86 V;  1VQ6 U;  3CCL U;  1S72 U;  3CCR U;  1YI2 U;  1Q81 V;  1VQ5 U;  1M90 V;  1M1K V;  3CMA U;  1VQL U;  1NJI V;  3CCV U;  1YJN U;  3CC7 U;  1K8A V;  1K9M V;  3CCS U;  2QA4 U;  3I55 U;  1VQK U;  3CCU U;  3G71 U;  5AN9 G;  3CC4 U;  1YIJ U;  3G6E U;  3I56 U;  1YJW U;  1QVG T;  2OTJ U;  1Q7Y V;  3CME U;  1YHQ U; 
#chains in the Genus database with same CATH topology
 1VQN U;  1YJ9 U;  5MLC Y;  3ANY A;  1VQ9 U;  3ABR A;  1W2B T;  1QVF T;  3CCR U;  1JJD A;  1VQL U;  4UY8 X;  1YJN U;  3CCS U;  3I55 U;  3ABQ A;  3G6E U;  2OTJ U;  1Q7Y V;  1KC8 V;  1YIT U;  1VQP U;  3CD6 U;  1VQM U;  3CPW T;  1VQ6 U;  3CCL U;  1S72 U;  1YI2 U;  1Q81 V;  1VQ5 U;  1M1K V;  3ABO A;  2QA4 U;  1VQK U;  3ABS A;  2QEZ A;  3G4S U;  1VQ7 U;  3J7Z X;  1VQ4 U;  3AO0 A;  3CCJ U;  3CCM U;  3OW2 T;  1N8R V;  1Q82 V;  1Q86 V;  1M90 V;  3CC7 U;  2JZ6 A;  1K8A V;  1YIJ U;  1YJW U;  1QVG T;  2OTL U;  1JJ2 T;  3CCQ U;  1K73 V;  3CXC T;  1VQO U;  5DM6 U;  1KD1 V;  1VQ8 U;  3CCE U;  5H1S Y;  1KQS T;  3CC2 U;  2QEX U;  3CMA U;  1NJI V;  3CCV U;  1K9M V;  3CCU U;  3G71 U;  5AN9 G;  3CC4 U;  3I56 U;  3CME U;  1YHQ U; 
#chains in the Genus database with same CATH homology
 2OTL U;  1JJ2 T;  3G4S U;  3CCQ U;  1VQ7 U;  1KC8 V;  1K73 V;  1YIT U;  3CXC T;  1VQP U;  1VQO U;  1VQ4 U;  3CCJ U;  1VQN U;  1YJ9 U;  3CD6 U;  3CCM U;  1KD1 V;  1VQ8 U;  1VQM U;  3CCE U;  1VQ9 U;  3OW2 T;  3CPW T;  1KQS T;  1W2B T;  1N8R V;  3CC2 U;  1QVF T;  2QEX U;  1Q82 V;  1Q86 V;  1VQ6 U;  3CCL U;  1S72 U;  3CCR U;  1JJD A;  1YI2 U;  1Q81 V;  1VQ5 U;  1M90 V;  1M1K V;  3CMA U;  1VQL U;  1NJI V;  3CCV U;  1YJN U;  3CC7 U;  1K8A V;  1K9M V;  3CCS U;  2QA4 U;  3I55 U;  1VQK U;  3CCU U;  3G71 U;  5AN9 G;  3CC4 U;  1YIJ U;  3G6E U;  3I56 U;  1YJW U;  1QVG T;  2OTJ U;  1Q7Y V;  3CME U;  1YHQ U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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