3CCLU

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 12
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
U PF01246 Ribosomal_L24e Ribosomal protein L24e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3cclU00
3CCEU 3G71U 1K8AV 3CCRU 3I55U 1VQ9U 1VQOU 1QVGT 3G4SU 3CC2U 1Q7YV 1KC8V 1M90V 1VQKU 5AN9G 1VQ8U 3CPWT 3CCJU 1QVFT 1YJWU 1Q86V 2QEXU 2OTLU 1YITU 1M1KV 1VQ6U 3CD6U 2OTJU 3CMAU 3OW2T 1YJ9U 1KQST 3CMEU 1S72U 1Q81V 3I56U 1N8RV 1VQ5U 1YI2U 3CC4U 3CCMU 1VQMU 1VQPU 3CXCT 3CCVU 3CCUU 3CCQU 1YJNU 1KD1V 1W2BT 3G6EU 1K9MV 1VQNU 3CC7U 1JJ2T 1YIJU 3CCSU 2QA4U 1VQ4U 1Q82V 1YHQU 3CCLU 1VQ7U 1K73V 1NJIV 1VQLU
chains in the Genus database with same CATH superfamily
1K8AV 1VQ9U 1KC8V 5MLCY 1S72U 3ABSA 1YI2U 3CC4U 3CCUU 1K9MV 1JJ2T 1VQ4U 3G71U 1Q7YV 1M90V 5AN9G 5DM6U 3CPWT 3CCJU 1QVFT 1Q86V 2QEXU 2OTLU 3CD6U 2OTJU 3ANYA 1VQPU 1VQMU 3CCVU 3G6EU 2QEZA 3CC7U 1YIJU 1YHQU 1K73V 5H1SY 1VQLU 3CCRU 3ABRA 1VQOU 1QVGT 3G4SU 1VQKU 1VQ8U 4UY8X 1YJWU 1YITU 1M1KV 1VQ6U 3CMAU 3OW2T 3CMEU 1Q81V 1VQ5U 1JJDA 3AO0A 3CCMU 1KD1V 3CXCT 1YJNU 3CCQU 1W2BT 1VQNU 3CCSU 2JZ6A 3CCLU 1VQ7U 1NJIV 3CCEU 3I55U 3ABQA 1YJ9U 1KQST 3I56U 1N8RV 3J7ZX 3ABOA 2QA4U 1Q82V 3CC2U
chains in the Genus database with same CATH topology
3CCEU 3G71U 1K8AV 3CCRU 3I55U 1VQ9U 1VQOU 1QVGT 3G4SU 3CC2U 1Q7YV 1KC8V 1M90V 1VQKU 5AN9G 1VQ8U 3CPWT 3CCJU 1QVFT 1YJWU 1Q86V 2QEXU 2OTLU 1YITU 1M1KV 1VQ6U 3CD6U 2OTJU 3CMAU 3OW2T 1YJ9U 1KQST 3CMEU 1S72U 1Q81V 3I56U 1N8RV 1VQ5U 1JJDA 1YI2U 3CC4U 3CCMU 1VQMU 1VQPU 3CXCT 3CCVU 3CCUU 3CCQU 1YJNU 1KD1V 1W2BT 3G6EU 1K9MV 1VQNU 3CC7U 1JJ2T 1YIJU 3CCSU 2QA4U 1VQ4U 1Q82V 1YHQU 3CCLU 1VQ7U 1K73V 1NJIV 1VQLU
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCE U;  3G71 U;  1K8A V;  3CCR U;  3I55 U;  1VQ9 U;  1VQO U;  1QVG T;  3G4S U;  3CC2 U;  1Q7Y V;  1KC8 V;  1M90 V;  1VQK U;  5AN9 G;  1VQ8 U;  3CPW T;  3CCJ U;  1QVF T;  1YJW U;  1Q86 V;  2QEX U;  2OTL U;  1YIT U;  1M1K V;  1VQ6 U;  3CD6 U;  2OTJ U;  3CMA U;  3OW2 T;  1YJ9 U;  1KQS T;  3CME U;  1S72 U;  1Q81 V;  3I56 U;  1N8R V;  1VQ5 U;  1YI2 U;  3CC4 U;  3CCM U;  1VQM U;  1VQP U;  3CXC T;  3CCV U;  3CCU U;  3CCQ U;  1YJN U;  1KD1 V;  1W2B T;  3G6E U;  1K9M V;  1VQN U;  3CC7 U;  1JJ2 T;  1YIJ U;  3CCS U;  2QA4 U;  1VQ4 U;  1Q82 V;  1YHQ U;  3CCL U;  1VQ7 U;  1K73 V;  1NJI V;  1VQL U; 
#chains in the Genus database with same CATH topology
 1K8A V;  1VQ9 U;  1KC8 V;  5MLC Y;  1S72 U;  3ABS A;  1YI2 U;  3CC4 U;  3CCU U;  1K9M V;  1JJ2 T;  1VQ4 U;  3G71 U;  1Q7Y V;  1M90 V;  5AN9 G;  5DM6 U;  3CPW T;  3CCJ U;  1QVF T;  1Q86 V;  2QEX U;  2OTL U;  3CD6 U;  2OTJ U;  3ANY A;  1VQP U;  1VQM U;  3CCV U;  3G6E U;  2QEZ A;  3CC7 U;  1YIJ U;  1YHQ U;  1K73 V;  5H1S Y;  1VQL U;  3CCR U;  3ABR A;  1VQO U;  1QVG T;  3G4S U;  1VQK U;  1VQ8 U;  4UY8 X;  1YJW U;  1YIT U;  1M1K V;  1VQ6 U;  3CMA U;  3OW2 T;  3CME U;  1Q81 V;  1VQ5 U;  1JJD A;  3AO0 A;  3CCM U;  1KD1 V;  3CXC T;  1YJN U;  3CCQ U;  1W2B T;  1VQN U;  3CCS U;  2JZ6 A;  3CCL U;  1VQ7 U;  1NJI V;  3CCE U;  3I55 U;  3ABQ A;  1YJ9 U;  1KQS T;  3I56 U;  1N8R V;  3J7Z X;  3ABO A;  2QA4 U;  1Q82 V;  3CC2 U; 
#chains in the Genus database with same CATH homology
 3CCE U;  3G71 U;  1K8A V;  3CCR U;  3I55 U;  1VQ9 U;  1VQO U;  1QVG T;  3G4S U;  3CC2 U;  1Q7Y V;  1KC8 V;  1M90 V;  1VQK U;  5AN9 G;  1VQ8 U;  3CPW T;  3CCJ U;  1QVF T;  1YJW U;  1Q86 V;  2QEX U;  2OTL U;  1YIT U;  1M1K V;  1VQ6 U;  3CD6 U;  2OTJ U;  3CMA U;  3OW2 T;  1YJ9 U;  1KQS T;  3CME U;  1S72 U;  1Q81 V;  3I56 U;  1N8R V;  1VQ5 U;  1JJD A;  1YI2 U;  3CC4 U;  3CCM U;  1VQM U;  1VQP U;  3CXC T;  3CCV U;  3CCU U;  3CCQ U;  1YJN U;  1KD1 V;  1W2B T;  3G6E U;  1K9M V;  1VQN U;  3CC7 U;  1JJ2 T;  1YIJ U;  3CCS U;  2QA4 U;  1VQ4 U;  1Q82 V;  1YHQ U;  3CCL U;  1VQ7 U;  1K73 V;  1NJI V;  1VQL U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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