3CCRU

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model.
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 6
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
U PF01246 Ribosomal_L24e Ribosomal protein L24e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3ccrU00
3CCVU 1YJNU 3CMEU 1YJWU 1VQNU 1VQPU 3G6EU 1Q82V 3CMAU 3CCQU 1VQ4U 3CC4U 5AN9G 1YIJU 1M90V 1VQ8U 1YITU 1K8AV 3CCLU 1NJIV 1KD1V 1VQKU 3CPWT 1Q86V 3I56U 3CCUU 1YJ9U 3CXCT 1JJ2T 1VQ6U 3CCMU 1VQMU 1M1KV 1QVFT 3G4SU 3OW2T 2OTLU 2OTJU 1QVGT 1S72U 2QA4U 3G71U 1VQOU 1YHQU 3CC2U 3CCRU 3CD6U 1KC8V 3I55U 1VQ9U 1VQ7U 1YI2U 1W2BT 3CCEU 2QEXU 3CCJU 3CCSU 1Q81V 1K73V 1N8RV 1KQST 1Q7YV 1VQLU 1VQ5U 3CC7U 1K9MV
chains in the Genus database with same CATH superfamily
1YJWU 1Q82V 3G6EU 1VQ4U 5H1SY 1NJIV 1KD1V 1VQKU 1Q86V 3CCUU 1YJ9U 1JJ2T 1M1KV 3G4SU 3OW2T 1S72U 1JJDA 1VQ9U 1YI2U 1W2BT 3CCSU 1N8RV 3CCVU 3CCQU 1M90V 1VQ8U 2QEZA 3ABSA 3ANYA 5DM6U 1QVFT 2OTJU 2OTLU 3CC2U 2QA4U 3G71U 1YHQU 3CD6U 3ABQA 3I55U 1VQ7U 1K73V 3ABRA 1Q81V 1KQST 1YJNU 3CMEU 1VQNU 1VQPU 5AN9G 1YIJU 3ABOA 1K8AV 3CCLU 3CPWT 3CXCT 2JZ6A 3CCMU 1QVGT 1VQOU 1KC8V 3CCEU 3J7ZX 1Q7YV 5MLCY 1VQ5U 3CC7U 1K9MV 3CMAU 4UY8X 1YITU 3I56U 1VQ6U 1VQMU 3AO0A 3CCRU 3CC4U 3CCJU 2QEXU 1VQLU
chains in the Genus database with same CATH topology
3CCVU 1YJNU 3CMEU 1YJWU 1VQNU 1VQPU 3G6EU 1Q82V 3CMAU 3CCQU 1VQ4U 3CC4U 5AN9G 1YIJU 1M90V 1VQ8U 1YITU 1K8AV 3CCLU 1NJIV 1KD1V 1VQKU 3CPWT 1Q86V 3I56U 3CCUU 1YJ9U 3CXCT 1JJ2T 1VQ6U 3CCMU 1VQMU 1M1KV 1QVFT 3G4SU 3OW2T 2OTLU 2OTJU 1QVGT 1S72U 1JJDA 3G71U 2QA4U 1VQOU 1YHQU 3CC2U 3CCRU 3CD6U 1KC8V 3I55U 1VQ9U 1VQ7U 1YI2U 1W2BT 3CCEU 2QEXU 3CCJU 3CCSU 1Q81V 1K73V 1N8RV 1KQST 1Q7YV 1VQLU 1VQ5U 3CC7U 1K9MV
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCV U;  1YJN U;  3CME U;  1YJW U;  1VQN U;  1VQP U;  3G6E U;  1Q82 V;  3CMA U;  3CCQ U;  1VQ4 U;  3CC4 U;  5AN9 G;  1YIJ U;  1M90 V;  1VQ8 U;  1YIT U;  1K8A V;  3CCL U;  1NJI V;  1KD1 V;  1VQK U;  3CPW T;  1Q86 V;  3I56 U;  3CCU U;  1YJ9 U;  3CXC T;  1JJ2 T;  1VQ6 U;  3CCM U;  1VQM U;  1M1K V;  1QVF T;  3G4S U;  3OW2 T;  2OTL U;  2OTJ U;  1QVG T;  1S72 U;  2QA4 U;  3G71 U;  1VQO U;  1YHQ U;  3CC2 U;  3CCR U;  3CD6 U;  1KC8 V;  3I55 U;  1VQ9 U;  1VQ7 U;  1YI2 U;  1W2B T;  3CCE U;  2QEX U;  3CCJ U;  3CCS U;  1Q81 V;  1K73 V;  1N8R V;  1KQS T;  1Q7Y V;  1VQL U;  1VQ5 U;  3CC7 U;  1K9M V; 
#chains in the Genus database with same CATH topology
 1YJW U;  1Q82 V;  3G6E U;  1VQ4 U;  5H1S Y;  1NJI V;  1KD1 V;  1VQK U;  1Q86 V;  3CCU U;  1YJ9 U;  1JJ2 T;  1M1K V;  3G4S U;  3OW2 T;  1S72 U;  1JJD A;  1VQ9 U;  1YI2 U;  1W2B T;  3CCS U;  1N8R V;  3CCV U;  3CCQ U;  1M90 V;  1VQ8 U;  2QEZ A;  3ABS A;  3ANY A;  5DM6 U;  1QVF T;  2OTJ U;  2OTL U;  3CC2 U;  2QA4 U;  3G71 U;  1YHQ U;  3CD6 U;  3ABQ A;  3I55 U;  1VQ7 U;  1K73 V;  3ABR A;  1Q81 V;  1KQS T;  1YJN U;  3CME U;  1VQN U;  1VQP U;  5AN9 G;  1YIJ U;  3ABO A;  1K8A V;  3CCL U;  3CPW T;  3CXC T;  2JZ6 A;  3CCM U;  1QVG T;  1VQO U;  1KC8 V;  3CCE U;  3J7Z X;  1Q7Y V;  5MLC Y;  1VQ5 U;  3CC7 U;  1K9M V;  3CMA U;  4UY8 X;  1YIT U;  3I56 U;  1VQ6 U;  1VQM U;  3AO0 A;  3CCR U;  3CC4 U;  3CCJ U;  2QEX U;  1VQL U; 
#chains in the Genus database with same CATH homology
 3CCV U;  1YJN U;  3CME U;  1YJW U;  1VQN U;  1VQP U;  3G6E U;  1Q82 V;  3CMA U;  3CCQ U;  1VQ4 U;  3CC4 U;  5AN9 G;  1YIJ U;  1M90 V;  1VQ8 U;  1YIT U;  1K8A V;  3CCL U;  1NJI V;  1KD1 V;  1VQK U;  3CPW T;  1Q86 V;  3I56 U;  3CCU U;  1YJ9 U;  3CXC T;  1JJ2 T;  1VQ6 U;  3CCM U;  1VQM U;  1M1K V;  1QVF T;  3G4S U;  3OW2 T;  2OTL U;  2OTJ U;  1QVG T;  1S72 U;  1JJD A;  3G71 U;  2QA4 U;  1VQO U;  1YHQ U;  3CC2 U;  3CCR U;  3CD6 U;  1KC8 V;  3I55 U;  1VQ9 U;  1VQ7 U;  1YI2 U;  1W2B T;  3CCE U;  2QEX U;  3CCJ U;  3CCS U;  1Q81 V;  1K73 V;  1N8R V;  1KQS T;  1Q7Y V;  1VQL U;  1VQ5 U;  3CC7 U;  1K9M V; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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