3CSCA

Structure of ternary complexes of citrate synthase with d-and l-malate: mechanistic implications
Total Genus 149
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
149
sequence length
433
structure length
429
Chain Sequence
ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGGGEPLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAAGADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYKIVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 1.9-A structures of ternary complexes of citrate synthase with D- and L-malate: mechanistic implications.
pubmed doi rcsb
molecule tags Oxo-acid-lyase
source organism Gallus gallus
molecule keywords CITRATE SYNTHASE
total genus 149
structure length 429
sequence length 433
ec nomenclature ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date 1990-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 3cscA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 3cscA01
1O7XA 4JAEA 2CSCA 2R26A 1OWCA 1CSIA 4YBOA 2P2WA 1AMZA 3HWKA 4CTSA 3TQGA 1CTSA 1VGMA 1VGPA 1AJ8A 3O8JA 1IOMA 2C6XA 4TVMA 5CSCA 6CSCA 1AL6A 1CSCA 4G6BA 2R9EA 5CSCB 4CSCA 1CSSA 3MSUA 6CTSA 2H12A 1A59A 1NXEA 3ENJA 4JAFA 4XGHA 1IXEA 2IBPA 1NXGA 4E6YA 1CSHA 2IFCA 5CTSA 2CTSA 3CSCA 1CSRA 1OWBA 4JAGA 4JADA
chains in the Genus database with same CATH superfamily
1O7XA 4JAEA 2CSCA 2R26A 1OWCA 1CSIA 4YBOA 2P2WA 1AMZA 3HWKA 4CTSA 3TQGA 1CTSA 1VGMA 1VGPA 1AJ8A 3O8JA 1IOMA 2C6XA 4TVMA 5CSCA 6CSCA 1AL6A 1CSCA 4G6BA 2R9EA 5CSCB 4CSCA 1CSSA 3MSUA 6CTSA 2H12A 1A59A 1NXEA 3ENJA 4JAFA 4XGHA 1IXEA 2IBPA 1NXGA 4E6YA 1CSHA 2IFCA 5CTSA 2CTSA 3CSCA 1CSRA 1OWBA 4JAGA 4JADA
chains in the Genus database with same CATH topology
1O7XA 4JAEA 2CSCA 2R26A 1OWCA 1CSIA 4YBOA 2P2WA 1AMZA 3HWKA 4CTSA 3TQGA 1CTSA 1VGMA 1VGPA 1AJ8A 3O8JA 1IOMA 2C6XA 4TVMA 5CSCA 6CSCA 1AL6A 1CSCA 4G6BA 2R9EA 5CSCB 4CSCA 1CSSA 3MSUA 6CTSA 2H12A 1A59A 1NXEA 3ENJA 4JAFA 4XGHA 1IXEA 2IBPA 1NXGA 4E6YA 1CSHA 2IFCA 5CTSA 2CTSA 3CSCA 1CSRA 1OWBA 4JAGA 4JADA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O7X A;  4JAE A;  2CSC A;  2R26 A;  1OWC A;  1CSI A;  4YBO A;  2P2W A;  1AMZ A;  3HWK A;  4CTS A;  3TQG A;  1CTS A;  1VGM A;  1VGP A;  1AJ8 A;  3O8J A;  1IOM A;  2C6X A;  4TVM A;  5CSC A;  6CSC A;  1AL6 A;  1CSC A;  4G6B A;  2R9E A;  5CSC B;  4CSC A;  1CSS A;  3MSU A;  6CTS A;  2H12 A;  1A59 A;  1NXE A;  3ENJ A;  4JAF A;  4XGH A;  1IXE A;  2IBP A;  1NXG A;  4E6Y A;  1CSH A;  2IFC A;  5CTS A;  2CTS A;  3CSC A;  1CSR A;  1OWB A;  4JAG A;  4JAD A; 
#chains in the Genus database with same CATH topology
 1O7X A;  4JAE A;  2CSC A;  2R26 A;  1OWC A;  1CSI A;  4YBO A;  2P2W A;  1AMZ A;  3HWK A;  4CTS A;  3TQG A;  1CTS A;  1VGM A;  1VGP A;  1AJ8 A;  3O8J A;  1IOM A;  2C6X A;  4TVM A;  5CSC A;  6CSC A;  1AL6 A;  1CSC A;  4G6B A;  2R9E A;  5CSC B;  4CSC A;  1CSS A;  3MSU A;  6CTS A;  2H12 A;  1A59 A;  1NXE A;  3ENJ A;  4JAF A;  4XGH A;  1IXE A;  2IBP A;  1NXG A;  4E6Y A;  1CSH A;  2IFC A;  5CTS A;  2CTS A;  3CSC A;  1CSR A;  1OWB A;  4JAG A;  4JAD A; 
#chains in the Genus database with same CATH homology
 1O7X A;  4JAE A;  2CSC A;  2R26 A;  1OWC A;  1CSI A;  4YBO A;  2P2W A;  1AMZ A;  3HWK A;  4CTS A;  3TQG A;  1CTS A;  1VGM A;  1VGP A;  1AJ8 A;  3O8J A;  1IOM A;  2C6X A;  4TVM A;  5CSC A;  6CSC A;  1AL6 A;  1CSC A;  4G6B A;  2R9E A;  5CSC B;  4CSC A;  1CSS A;  3MSU A;  6CTS A;  2H12 A;  1A59 A;  1NXE A;  3ENJ A;  4JAF A;  4XGH A;  1IXE A;  2IBP A;  1NXG A;  4E6Y A;  1CSH A;  2IFC A;  5CTS A;  2CTS A;  3CSC A;  1CSR A;  1OWB A;  4JAG A;  4JAD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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