3CXCT

The structure of an enhanced oxazolidinone inhibitor bound to the 50s ribosomal subunit of h. marismortui
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
pubmed doi rcsb
molecule keywords 23S RIBOSOMAL RNA
molecule tags Ribosome
total genus 10
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2008-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
T PF01246 Ribosomal_L24e Ribosomal protein L24e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3cxcT00
3CMAU 3CD6U 1YI2U 1K9MV 1VQLU 1Q86V 2OTJU 1JJ2T 2QEXU 3CCVU 1VQPU 3G71U 1VQ5U 3CCUU 2QA4U 1Q7YV 1VQMU 1YITU 1VQ4U 1VQKU 1YHQU 3G4SU 1M90V 3CXCT 3CCRU 1K8AV 3G6EU 1VQ9U 1VQNU 1YJNU 3CCSU 1KD1V 1M1KV 1VQ7U 1QVGT 1K73V 1YJWU 1VQ6U 3CCJU 3CCMU 3CMEU 1Q81V 3CCEU 3CCLU 1VQOU 1YJ9U 1VQ8U 3CPWT 3CCQU 1QVFT 3I55U 1KC8V 1KQST 2OTLU 3CC7U 3OW2T 1NJIV 5AN9G 3I56U 1S72U 1N8RV 1W2BT 3CC2U 1Q82V 1YIJU 3CC4U
chains in the Genus database with same CATH superfamily
1VQLU 1M90V 1M1KV 1QVGT 4UY8X 3CCJU 3CCEU 3CPWT 1KC8V 3I56U 1S72U 3CC2U 3CC4U 1VQ5U 1Q82V 2QEZA 1YI2U 1K9MV 1VQ4U 1VQKU 3CCRU 3J7ZX 3G6EU 1VQNU 1YJWU 1VQ6U 3CCMU 1Q81V 3AO0A 1YJ9U 2JZ6A 1KQST 3OW2T 1YIJU 3CMAU 3CD6U 2OTJU 1VQPU 3ABOA 5H1SY 3CCUU 2QA4U 3ANYA 1Q7YV 1VQMU 1YITU 1YHQU 1K8AV 1VQ9U 3ABRA 3CCSU 1VQ7U 3CMEU 3CCLU 3CCQU 1QVFT 3I55U 2OTLU 1W2BT 1Q86V 1JJ2T 2QEXU 3CCVU 3G71U 3ABSA 3ABQA 3G4SU 3CXCT 1YJNU 1KD1V 1JJDA 5DM6U 1K73V 1VQOU 5MLCY 1VQ8U 3CC7U 1NJIV 5AN9G 1N8RV
chains in the Genus database with same CATH topology
3CMAU 3CD6U 1YI2U 1K9MV 1VQLU 1Q86V 2OTJU 1JJ2T 2QEXU 3CCVU 1VQPU 3G71U 1VQ5U 3CCUU 2QA4U 1Q7YV 1VQMU 1YITU 1VQ4U 1VQKU 1YHQU 3G4SU 1M90V 3CXCT 3CCRU 1K8AV 3G6EU 1VQ9U 1VQNU 1YJNU 3CCSU 1KD1V 1JJDA 1M1KV 1VQ7U 1QVGT 1K73V 1YJWU 1VQ6U 3CCJU 3CCMU 3CMEU 1Q81V 3CCEU 3CCLU 1VQOU 1YJ9U 1VQ8U 3CPWT 3CCQU 1QVFT 3I55U 1KC8V 1KQST 2OTLU 3CC7U 3OW2T 1NJIV 5AN9G 3I56U 1S72U 1N8RV 1W2BT 3CC2U 1Q82V 1YIJU 3CC4U
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CMA U;  3CD6 U;  1YI2 U;  1K9M V;  1VQL U;  1Q86 V;  2OTJ U;  1JJ2 T;  2QEX U;  3CCV U;  1VQP U;  3G71 U;  1VQ5 U;  3CCU U;  2QA4 U;  1Q7Y V;  1VQM U;  1YIT U;  1VQ4 U;  1VQK U;  1YHQ U;  3G4S U;  1M90 V;  3CXC T;  3CCR U;  1K8A V;  3G6E U;  1VQ9 U;  1VQN U;  1YJN U;  3CCS U;  1KD1 V;  1M1K V;  1VQ7 U;  1QVG T;  1K73 V;  1YJW U;  1VQ6 U;  3CCJ U;  3CCM U;  3CME U;  1Q81 V;  3CCE U;  3CCL U;  1VQO U;  1YJ9 U;  1VQ8 U;  3CPW T;  3CCQ U;  1QVF T;  3I55 U;  1KC8 V;  1KQS T;  2OTL U;  3CC7 U;  3OW2 T;  1NJI V;  5AN9 G;  3I56 U;  1S72 U;  1N8R V;  1W2B T;  3CC2 U;  1Q82 V;  1YIJ U;  3CC4 U; 
#chains in the Genus database with same CATH topology
 1VQL U;  1M90 V;  1M1K V;  1QVG T;  4UY8 X;  3CCJ U;  3CCE U;  3CPW T;  1KC8 V;  3I56 U;  1S72 U;  3CC2 U;  3CC4 U;  1VQ5 U;  1Q82 V;  2QEZ A;  1YI2 U;  1K9M V;  1VQ4 U;  1VQK U;  3CCR U;  3J7Z X;  3G6E U;  1VQN U;  1YJW U;  1VQ6 U;  3CCM U;  1Q81 V;  3AO0 A;  1YJ9 U;  2JZ6 A;  1KQS T;  3OW2 T;  1YIJ U;  3CMA U;  3CD6 U;  2OTJ U;  1VQP U;  3ABO A;  5H1S Y;  3CCU U;  2QA4 U;  3ANY A;  1Q7Y V;  1VQM U;  1YIT U;  1YHQ U;  1K8A V;  1VQ9 U;  3ABR A;  3CCS U;  1VQ7 U;  3CME U;  3CCL U;  3CCQ U;  1QVF T;  3I55 U;  2OTL U;  1W2B T;  1Q86 V;  1JJ2 T;  2QEX U;  3CCV U;  3G71 U;  3ABS A;  3ABQ A;  3G4S U;  3CXC T;  1YJN U;  1KD1 V;  1JJD A;  5DM6 U;  1K73 V;  1VQO U;  5MLC Y;  1VQ8 U;  3CC7 U;  1NJI V;  5AN9 G;  1N8R V; 
#chains in the Genus database with same CATH homology
 3CMA U;  3CD6 U;  1YI2 U;  1K9M V;  1VQL U;  1Q86 V;  2OTJ U;  1JJ2 T;  2QEX U;  3CCV U;  1VQP U;  3G71 U;  1VQ5 U;  3CCU U;  2QA4 U;  1Q7Y V;  1VQM U;  1YIT U;  1VQ4 U;  1VQK U;  1YHQ U;  3G4S U;  1M90 V;  3CXC T;  3CCR U;  1K8A V;  3G6E U;  1VQ9 U;  1VQN U;  1YJN U;  3CCS U;  1KD1 V;  1JJD A;  1M1K V;  1VQ7 U;  1QVG T;  1K73 V;  1YJW U;  1VQ6 U;  3CCJ U;  3CCM U;  3CME U;  1Q81 V;  3CCE U;  3CCL U;  1VQO U;  1YJ9 U;  1VQ8 U;  3CPW T;  3CCQ U;  1QVF T;  3I55 U;  1KC8 V;  1KQS T;  2OTL U;  3CC7 U;  3OW2 T;  1NJI V;  5AN9 G;  3I56 U;  1S72 U;  1N8R V;  1W2B T;  3CC2 U;  1Q82 V;  1YIJ U;  3CC4 U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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