3CXCT

The structure of an enhanced oxazolidinone inhibitor bound to the 50s ribosomal subunit of h. marismortui
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
pubmed doi rcsb
molecule keywords 23S RIBOSOMAL RNA
molecule tags Ribosome
total genus 10
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2008-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
T PF01246 Ribosomal_L24e Ribosomal protein L24e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3cxcT00
1S72U 3OW2T 1VQNU 1Q7YV 1JJ2T 1K8AV 1VQ5U 1K73V 1VQPU 2QA4U 3CC4U 2OTJU 1VQOU 3CMAU 3CCLU 3CMEU 3G71U 1KC8V 1K9MV 1VQ6U 3CCSU 1YITU 3G6EU 1YJ9U 1Q86V 1VQ9U 1M1KV 3CCJU 1N8RV 1YIJU 1KD1V 1VQ4U 5AN9G 1M90V 1QVFT 3CCMU 3CCRU 3CPWT 1VQ7U 1NJIV 1Q81V 2OTLU 3CXCT 3CC2U 1QVGT 3CCQU 1VQKU 1YI2U 3CD6U 1VQMU 1YJWU 3CCVU 3CCUU 3G4SU 3CC7U 3I56U 1VQ8U 1YJNU 1VQLU 1KQST 3CCEU 1Q82V 1W2BT 2QEXU 1YHQU 3I55U
chains in the Genus database with same CATH superfamily
1JJ2T 1VQPU 2QA4U 3J7ZX 2QEZA 1YITU 1VQ4U 1Q81V 2OTLU 3CC2U 1VQMU 3CCVU 3I56U 1YJNU 3OW2T 1VQ5U 1K73V 3CCLU 3CMEU 3G71U 1YJ9U 1Q86V 1N8RV 1M90V 3CCRU 3ANYA 3CPWT 1NJIV 2JZ6A 1QVGT 3CCQU 1VQKU 1YI2U 3CC7U 5DM6U 3AO0A 5MLCY 1Q82V 1W2BT 1YHQU 3ABOA 3ABQA 1K8AV 3CC4U 2OTJU 1KC8V 5H1SY 3G6EU 1VQ9U 1M1KV 1QVFT 5AN9G 3CCMU 3CXCT 1KQST 3CCEU 1S72U 1VQNU 1Q7YV 1VQOU 3CMAU 4UY8X 1K9MV 3ABRA 1VQ6U 1JJDA 3CCSU 3CCJU 1YIJU 1KD1V 1VQ7U 3CD6U 1YJWU 3CCUU 3G4SU 1VQ8U 1VQLU 2QEXU 3ABSA 3I55U
chains in the Genus database with same CATH topology
1S72U 3OW2T 1VQNU 1Q7YV 1JJ2T 1K8AV 1VQ5U 1K73V 1VQPU 2QA4U 3CC4U 2OTJU 1VQOU 3CMAU 3CCLU 3CMEU 3G71U 1KC8V 1K9MV 1VQ6U 1JJDA 3CCSU 1YITU 3G6EU 1YJ9U 1Q86V 1VQ9U 1M1KV 3CCJU 1N8RV 1YIJU 1KD1V 1VQ4U 5AN9G 1M90V 1QVFT 3CCMU 3CCRU 3CPWT 1VQ7U 1NJIV 1Q81V 2OTLU 3CXCT 3CC2U 1QVGT 3CCQU 1VQKU 1YI2U 3CD6U 1VQMU 1YJWU 3CCVU 3CCUU 3G4SU 3CC7U 3I56U 1VQ8U 1YJNU 1VQLU 1KQST 3CCEU 1Q82V 1W2BT 2QEXU 1YHQU 3I55U
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S72 U;  3OW2 T;  1VQN U;  1Q7Y V;  1JJ2 T;  1K8A V;  1VQ5 U;  1K73 V;  1VQP U;  2QA4 U;  3CC4 U;  2OTJ U;  1VQO U;  3CMA U;  3CCL U;  3CME U;  3G71 U;  1KC8 V;  1K9M V;  1VQ6 U;  3CCS U;  1YIT U;  3G6E U;  1YJ9 U;  1Q86 V;  1VQ9 U;  1M1K V;  3CCJ U;  1N8R V;  1YIJ U;  1KD1 V;  1VQ4 U;  5AN9 G;  1M90 V;  1QVF T;  3CCM U;  3CCR U;  3CPW T;  1VQ7 U;  1NJI V;  1Q81 V;  2OTL U;  3CXC T;  3CC2 U;  1QVG T;  3CCQ U;  1VQK U;  1YI2 U;  3CD6 U;  1VQM U;  1YJW U;  3CCV U;  3CCU U;  3G4S U;  3CC7 U;  3I56 U;  1VQ8 U;  1YJN U;  1VQL U;  1KQS T;  3CCE U;  1Q82 V;  1W2B T;  2QEX U;  1YHQ U;  3I55 U; 
#chains in the Genus database with same CATH topology
 1JJ2 T;  1VQP U;  2QA4 U;  3J7Z X;  2QEZ A;  1YIT U;  1VQ4 U;  1Q81 V;  2OTL U;  3CC2 U;  1VQM U;  3CCV U;  3I56 U;  1YJN U;  3OW2 T;  1VQ5 U;  1K73 V;  3CCL U;  3CME U;  3G71 U;  1YJ9 U;  1Q86 V;  1N8R V;  1M90 V;  3CCR U;  3ANY A;  3CPW T;  1NJI V;  2JZ6 A;  1QVG T;  3CCQ U;  1VQK U;  1YI2 U;  3CC7 U;  5DM6 U;  3AO0 A;  5MLC Y;  1Q82 V;  1W2B T;  1YHQ U;  3ABO A;  3ABQ A;  1K8A V;  3CC4 U;  2OTJ U;  1KC8 V;  5H1S Y;  3G6E U;  1VQ9 U;  1M1K V;  1QVF T;  5AN9 G;  3CCM U;  3CXC T;  1KQS T;  3CCE U;  1S72 U;  1VQN U;  1Q7Y V;  1VQO U;  3CMA U;  4UY8 X;  1K9M V;  3ABR A;  1VQ6 U;  1JJD A;  3CCS U;  3CCJ U;  1YIJ U;  1KD1 V;  1VQ7 U;  3CD6 U;  1YJW U;  3CCU U;  3G4S U;  1VQ8 U;  1VQL U;  2QEX U;  3ABS A;  3I55 U; 
#chains in the Genus database with same CATH homology
 1S72 U;  3OW2 T;  1VQN U;  1Q7Y V;  1JJ2 T;  1K8A V;  1VQ5 U;  1K73 V;  1VQP U;  2QA4 U;  3CC4 U;  2OTJ U;  1VQO U;  3CMA U;  3CCL U;  3CME U;  3G71 U;  1KC8 V;  1K9M V;  1VQ6 U;  1JJD A;  3CCS U;  1YIT U;  3G6E U;  1YJ9 U;  1Q86 V;  1VQ9 U;  1M1K V;  3CCJ U;  1N8R V;  1YIJ U;  1KD1 V;  1VQ4 U;  5AN9 G;  1M90 V;  1QVF T;  3CCM U;  3CCR U;  3CPW T;  1VQ7 U;  1NJI V;  1Q81 V;  2OTL U;  3CXC T;  3CC2 U;  1QVG T;  3CCQ U;  1VQK U;  1YI2 U;  3CD6 U;  1VQM U;  1YJW U;  3CCV U;  3CCU U;  3G4S U;  3CC7 U;  3I56 U;  1VQ8 U;  1YJN U;  1VQL U;  1KQS T;  3CCE U;  1Q82 V;  1W2B T;  2QEX U;  1YHQ U;  3I55 U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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