3D1FA

Crystal structure of e. coli sliding clamp (beta) bound to a polymerase iii peptide
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
366
structure length
366
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
pubmed doi rcsb
molecule tags Transferase, transcription
source organism Escherichia coli
molecule keywords DNA polymerase III subunit beta
total genus 86
structure length 366
sequence length 366
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2008-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3d1fA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3d1fA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3d1fA01
3F1VA 4PNWA 4N97A 3Q4KA 4K3MA 3L0WA 4TSZA 4MJQA 2XURA 2AWAA 4K3SA 3PGEB 4OVHA 4N98A 2POLA 4N9AA 4K3QA 3L10A 4OVGA 4N99A 4K3RA 4OVFA 3BEPA 3L0XA 1JQLA 4S3IA 1OK7A 4K3LA 4N94A 3D1GA 4PNVA 4K3OA 3D1EA 5AH4A 4RKIA 4K3PA 3QSBA 5FRQA 3D1FA 3RB9A 4N95A 1UNNA 3QSBB 4TRTA 3PWEA 1VPKA 5AGVA 5FVEA 4TR8A 2AVTA 4PNUA 4K3KA 1JQJA 4K74A 4MJRA 3Q4LA 1MMIA 5AGUA 4TR7A 5AH2A 3T0PA 3P16A 4TR6A 4MJPA 4N96A 3Q4JA
chains in the Genus database with same CATH superfamily
3F1VA 4PNWA 4N97A 3Q4KA 4K3MA 3L0WA 4TSZA 3PGEA 4MJQA 2XURA 2AWAA 3L0WB 4K3SA 3PGEB 4OVHA 4N98A 2POLA 4N9AA 4K3QA 3L10A 4OVGA 3L10B 4N99A 4K3RA 4OVFA 3BEPA 3L0XA 1JQLA 3L0XB 4S3IA 1OK7A 4K3LA 4N94A 3D1GA 4PNVA 4K3OA 3D1EA 5AH4A 4RKIA 4K3PA 3QSBA 5FRQA 3D1FA 3RB9A 4N95A 1UNNA 3QSBB 4TRTA 3PWEA 1VPKA 5AGVA 5FVEA 4TR8A 2AVTA 4PNUA 4K3KA 1JQJA 4K74A 4MJRA 3Q4LA 1MMIA 5AGUA 4TR7A 5AH2A 3T0PA 3P16A 4TR6A 4MJPA 4N96A 3Q4JA
chains in the Genus database with same CATH topology
3F1VA 4PNWA 4N97A 3Q4KA 4K3MA 3L0WA 4TSZA 4MJQA 2XURA 2AWAA 4K3SA 3PGEB 4OVHA 4N98A 2POLA 4N9AA 4K3QA 3L10A 4OVGA 4N99A 4K3RA 4OVFA 3BEPA 3L0XA 1JQLA 4S3IA 1OK7A 4K3LA 4N94A 3D1GA 4PNVA 4K3OA 3D1EA 5AH4A 4RKIA 4K3PA 3QSBA 5FRQA 3D1FA 3RB9A 4N95A 1UNNA 3QSBB 4TRTA 3PWEA 1VPKA 5AGVA 5FVEA 4TR8A 2AVTA 4PNUA 4K3KA 1JQJA 4K74A 4MJRA 3Q4LA 1MMIA 5AGUA 4TR7A 5AH2A 3T0PA 3P16A 4TR6A 4MJPA 4N96A 3Q4JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F1V A;  4PNW A;  4N97 A;  3Q4K A;  4K3M A;  3L0W A;  4TSZ A;  4MJQ A;  2XUR A;  2AWA A;  4K3S A;  3PGE B;  4OVH A;  4N98 A;  2POL A;  4N9A A;  4K3Q A;  3L10 A;  4OVG A;  4N99 A;  4K3R A;  4OVF A;  3BEP A;  3L0X A;  1JQL A;  4S3I A;  1OK7 A;  4K3L A;  4N94 A;  3D1G A;  4PNV A;  4K3O A;  3D1E A;  5AH4 A;  4RKI A;  4K3P A;  3QSB A;  5FRQ A;  3D1F A;  3RB9 A;  4N95 A;  1UNN A;  3QSB B;  4TRT A;  3PWE A;  1VPK A;  5AGV A;  5FVE A;  4TR8 A;  2AVT A;  4PNU A;  4K3K A;  1JQJ A;  4K74 A;  4MJR A;  3Q4L A;  1MMI A;  5AGU A;  4TR7 A;  5AH2 A;  3T0P A;  3P16 A;  4TR6 A;  4MJP A;  4N96 A;  3Q4J A; 
#chains in the Genus database with same CATH topology
 3F1V A;  4PNW A;  4N97 A;  3Q4K A;  4K3M A;  3L0W A;  4TSZ A;  3PGE A;  4MJQ A;  2XUR A;  2AWA A;  3L0W B;  4K3S A;  3PGE B;  4OVH A;  4N98 A;  2POL A;  4N9A A;  4K3Q A;  3L10 A;  4OVG A;  3L10 B;  4N99 A;  4K3R A;  4OVF A;  3BEP A;  3L0X A;  1JQL A;  3L0X B;  4S3I A;  1OK7 A;  4K3L A;  4N94 A;  3D1G A;  4PNV A;  4K3O A;  3D1E A;  5AH4 A;  4RKI A;  4K3P A;  3QSB A;  5FRQ A;  3D1F A;  3RB9 A;  4N95 A;  1UNN A;  3QSB B;  4TRT A;  3PWE A;  1VPK A;  5AGV A;  5FVE A;  4TR8 A;  2AVT A;  4PNU A;  4K3K A;  1JQJ A;  4K74 A;  4MJR A;  3Q4L A;  1MMI A;  5AGU A;  4TR7 A;  5AH2 A;  3T0P A;  3P16 A;  4TR6 A;  4MJP A;  4N96 A;  3Q4J A; 
#chains in the Genus database with same CATH homology
 3F1V A;  4PNW A;  4N97 A;  3Q4K A;  4K3M A;  3L0W A;  4TSZ A;  4MJQ A;  2XUR A;  2AWA A;  4K3S A;  3PGE B;  4OVH A;  4N98 A;  2POL A;  4N9A A;  4K3Q A;  3L10 A;  4OVG A;  4N99 A;  4K3R A;  4OVF A;  3BEP A;  3L0X A;  1JQL A;  4S3I A;  1OK7 A;  4K3L A;  4N94 A;  3D1G A;  4PNV A;  4K3O A;  3D1E A;  5AH4 A;  4RKI A;  4K3P A;  3QSB A;  5FRQ A;  3D1F A;  3RB9 A;  4N95 A;  1UNN A;  3QSB B;  4TRT A;  3PWE A;  1VPK A;  5AGV A;  5FVE A;  4TR8 A;  2AVT A;  4PNU A;  4K3K A;  1JQJ A;  4K74 A;  4MJR A;  3Q4L A;  1MMI A;  5AGU A;  4TR7 A;  5AH2 A;  3T0P A;  3P16 A;  4TR6 A;  4MJP A;  4N96 A;  3Q4J A; 
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