3D1GA

Structure of a small molecule inhibitor bound to a dna sliding clamp
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
366
structure length
366
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
pubmed doi rcsb
molecule tags Transferase, transcription
source organism Escherichia coli
molecule keywords DNA polymerase III subunit beta
total genus 88
structure length 366
sequence length 366
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2008-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3d1gA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3d1gA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3d1gA01
4N98A 4TRTA 3L0XA 4TR6A 3D1EA 4PNWA 4N96A 1JQJA 4TR7A 4K3OA 3D1GA 3Q4JA 4K3PA 4OVHA 3Q4KA 4K74A 1MMIA 3QSBA 3F1VA 1OK7A 4OVFA 4K3QA 3L0WA 4TR8A 2XURA 3PGEB 4K3KA 4N94A 5AGVA 3T0PA 3BEPA 1JQLA 4N99A 1VPKA 3L10A 4K3MA 4S3IA 4PNVA 4MJQA 5AH2A 5AGUA 2AWAA 4N9AA 4K3RA 4N97A 1UNNA 4OVGA 4PNUA 4K3LA 4MJRA 5FVEA 3P16A 2POLA 5FRQA 3RB9A 5AH4A 4RKIA 4TSZA 3Q4LA 3PWEA 2AVTA 4N95A 4K3SA 4MJPA 3QSBB 3D1FA
chains in the Genus database with same CATH superfamily
4N98A 4TRTA 3L0XA 4TR6A 3D1EA 3L0WB 4PNWA 4N96A 1JQJA 3L10B 4TR7A 4K3OA 3D1GA 3Q4JA 4K3PA 4OVHA 3Q4KA 4K74A 1MMIA 3QSBA 3F1VA 1OK7A 4OVFA 4K3QA 3L0WA 4TR8A 2XURA 3PGEB 4K3KA 4N94A 5AGVA 3T0PA 3BEPA 1JQLA 4N99A 1VPKA 3L10A 4K3MA 4S3IA 4PNVA 4MJQA 5AH2A 5AGUA 2AWAA 4N9AA 4K3RA 3L0XB 1UNNA 4N97A 4OVGA 4K3LA 4MJRA 4PNUA 5FVEA 3P16A 2POLA 5FRQA 3RB9A 5AH4A 3PGEA 4RKIA 4TSZA 3Q4LA 3PWEA 2AVTA 4N95A 4K3SA 4MJPA 3QSBB 3D1FA
chains in the Genus database with same CATH topology
4N98A 4TRTA 3L0XA 4TR6A 3D1EA 4PNWA 4N96A 1JQJA 4TR7A 4K3OA 3D1GA 3Q4JA 4K3PA 4OVHA 3Q4KA 4K74A 1MMIA 3QSBA 3F1VA 1OK7A 4OVFA 4K3QA 3L0WA 4TR8A 2XURA 3PGEB 4K3KA 4N94A 5AGVA 3T0PA 3BEPA 1JQLA 4N99A 1VPKA 3L10A 4K3MA 4S3IA 4PNVA 4MJQA 5AH2A 5AGUA 2AWAA 4N9AA 4K3RA 4N97A 1UNNA 4OVGA 4PNUA 4K3LA 4MJRA 5FVEA 3P16A 2POLA 5FRQA 3RB9A 5AH4A 4RKIA 4TSZA 3Q4LA 3PWEA 2AVTA 4N95A 4K3SA 4MJPA 3QSBB 3D1FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N98 A;  4TRT A;  3L0X A;  4TR6 A;  3D1E A;  4PNW A;  4N96 A;  1JQJ A;  4TR7 A;  4K3O A;  3D1G A;  3Q4J A;  4K3P A;  4OVH A;  3Q4K A;  4K74 A;  1MMI A;  3QSB A;  3F1V A;  1OK7 A;  4OVF A;  4K3Q A;  3L0W A;  4TR8 A;  2XUR A;  3PGE B;  4K3K A;  4N94 A;  5AGV A;  3T0P A;  3BEP A;  1JQL A;  4N99 A;  1VPK A;  3L10 A;  4K3M A;  4S3I A;  4PNV A;  4MJQ A;  5AH2 A;  5AGU A;  2AWA A;  4N9A A;  4K3R A;  4N97 A;  1UNN A;  4OVG A;  4PNU A;  4K3L A;  4MJR A;  5FVE A;  3P16 A;  2POL A;  5FRQ A;  3RB9 A;  5AH4 A;  4RKI A;  4TSZ A;  3Q4L A;  3PWE A;  2AVT A;  4N95 A;  4K3S A;  4MJP A;  3QSB B;  3D1F A; 
#chains in the Genus database with same CATH topology
 4N98 A;  4TRT A;  3L0X A;  4TR6 A;  3D1E A;  3L0W B;  4PNW A;  4N96 A;  1JQJ A;  3L10 B;  4TR7 A;  4K3O A;  3D1G A;  3Q4J A;  4K3P A;  4OVH A;  3Q4K A;  4K74 A;  1MMI A;  3QSB A;  3F1V A;  1OK7 A;  4OVF A;  4K3Q A;  3L0W A;  4TR8 A;  2XUR A;  3PGE B;  4K3K A;  4N94 A;  5AGV A;  3T0P A;  3BEP A;  1JQL A;  4N99 A;  1VPK A;  3L10 A;  4K3M A;  4S3I A;  4PNV A;  4MJQ A;  5AH2 A;  5AGU A;  2AWA A;  4N9A A;  4K3R A;  3L0X B;  1UNN A;  4N97 A;  4OVG A;  4K3L A;  4MJR A;  4PNU A;  5FVE A;  3P16 A;  2POL A;  5FRQ A;  3RB9 A;  5AH4 A;  3PGE A;  4RKI A;  4TSZ A;  3Q4L A;  3PWE A;  2AVT A;  4N95 A;  4K3S A;  4MJP A;  3QSB B;  3D1F A; 
#chains in the Genus database with same CATH homology
 4N98 A;  4TRT A;  3L0X A;  4TR6 A;  3D1E A;  4PNW A;  4N96 A;  1JQJ A;  4TR7 A;  4K3O A;  3D1G A;  3Q4J A;  4K3P A;  4OVH A;  3Q4K A;  4K74 A;  1MMI A;  3QSB A;  3F1V A;  1OK7 A;  4OVF A;  4K3Q A;  3L0W A;  4TR8 A;  2XUR A;  3PGE B;  4K3K A;  4N94 A;  5AGV A;  3T0P A;  3BEP A;  1JQL A;  4N99 A;  1VPK A;  3L10 A;  4K3M A;  4S3I A;  4PNV A;  4MJQ A;  5AH2 A;  5AGU A;  2AWA A;  4N9A A;  4K3R A;  4N97 A;  1UNN A;  4OVG A;  4PNU A;  4K3L A;  4MJR A;  5FVE A;  3P16 A;  2POL A;  5FRQ A;  3RB9 A;  5AH4 A;  4RKI A;  4TSZ A;  3Q4L A;  3PWE A;  2AVT A;  4N95 A;  4K3S A;  4MJP A;  3QSB B;  3D1F A; 
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