3G4SU

Co-crystal structure of tiamulin bound to the large ribosomal subunit
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule keywords 23S ribosomal RNA
total genus 6
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2009-02-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3g4sU00
3CXCT 1YHQU 1KD1V 3CCVU 3CCLU 1K9MV 1YJNU 1K73V 3CCQU 1N8RV 1VQLU 1M90V 3CMAU 3CC4U 2QA4U 3CPWT 3OW2T 1VQOU 1QVGT 3G4SU 1KQST 1Q7YV 2OTJU 1QVFT 3CCMU 3CMEU 1NJIV 1YJ9U 3CC2U 1KC8V 2OTLU 1VQ8U 1VQ5U 1VQNU 1YIJU 2QEXU 1Q82V 1JJ2T 1Q86V 1VQKU 3CCRU 1YI2U 3I56U 3CCJU 3G6EU 1S72U 3G71U 3CCUU 3CD6U 1YJWU 1VQ4U 1VQMU 1W2BT 1K8AV 1M1KV 3I55U 1VQ6U 3CCSU 1VQPU 1YITU 1VQ9U 1Q81V 3CC7U 1VQ7U 5AN9G 3CCEU
chains in the Genus database with same CATH superfamily
1YHQU 1K73V 3CPWT 4UY8X 3ABQA 1YJ9U 2QEZA 1YIJU 2QEXU 1JJ2T 3I56U 1JJDA 1S72U 3G71U 3CCUU 3CD6U 3I55U 1VQ6U 1VQ9U 3CCVU 3CCLU 3OW2T 2OTJU 3G4SU 3CMEU 1NJIV 2OTLU 1VQ8U 3G6EU 3ABSA 1VQMU 3ABOA 1VQ7U 3ANYA 3CCQU 3ABRA 1N8RV 1VQLU 3CMAU 1QVGT 1KQST 1Q7YV 3CC2U 1KC8V 1VQ5U 1Q82V 1VQKU 1YI2U 5DM6U 1VQ4U 5H1SY 1VQPU 3CC7U 2JZ6A 5AN9G 3CXCT 5MLCY 1KD1V 1K9MV 1YJNU 1M90V 3CC4U 2QA4U 1VQOU 1QVFT 3CCMU 1VQNU 1Q86V 3CCRU 3CCJU 3AO0A 1YJWU 3J7ZX 1W2BT 1K8AV 3CCSU 1YITU 1Q81V 1M1KV 3CCEU
chains in the Genus database with same CATH topology
3CXCT 1YHQU 1KD1V 3CCVU 3CCLU 1K9MV 1YJNU 1K73V 3CCQU 1N8RV 1VQLU 1M90V 3CMAU 3CC4U 2QA4U 3CPWT 3OW2T 1VQOU 1QVGT 3G4SU 1KQST 1Q7YV 2OTJU 1QVFT 3CCMU 3CMEU 1NJIV 1YJ9U 3CC2U 1KC8V 2OTLU 1VQ8U 1VQ5U 1VQNU 1YIJU 2QEXU 1Q82V 1JJ2T 1Q86V 1VQKU 3CCRU 1YI2U 3I56U 3CCJU 1JJDA 3G6EU 1S72U 3G71U 3CCUU 3CD6U 1YJWU 1VQ4U 1VQMU 1W2BT 1K8AV 1M1KV 3I55U 1VQ6U 3CCSU 1VQPU 1YITU 1VQ9U 1Q81V 3CC7U 1VQ7U 5AN9G 3CCEU
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CXC T;  1YHQ U;  1KD1 V;  3CCV U;  3CCL U;  1K9M V;  1YJN U;  1K73 V;  3CCQ U;  1N8R V;  1VQL U;  1M90 V;  3CMA U;  3CC4 U;  2QA4 U;  3CPW T;  3OW2 T;  1VQO U;  1QVG T;  3G4S U;  1KQS T;  1Q7Y V;  2OTJ U;  1QVF T;  3CCM U;  3CME U;  1NJI V;  1YJ9 U;  3CC2 U;  1KC8 V;  2OTL U;  1VQ8 U;  1VQ5 U;  1VQN U;  1YIJ U;  2QEX U;  1Q82 V;  1JJ2 T;  1Q86 V;  1VQK U;  3CCR U;  1YI2 U;  3I56 U;  3CCJ U;  3G6E U;  1S72 U;  3G71 U;  3CCU U;  3CD6 U;  1YJW U;  1VQ4 U;  1VQM U;  1W2B T;  1K8A V;  1M1K V;  3I55 U;  1VQ6 U;  3CCS U;  1VQP U;  1YIT U;  1VQ9 U;  1Q81 V;  3CC7 U;  1VQ7 U;  5AN9 G;  3CCE U; 
#chains in the Genus database with same CATH topology
 1YHQ U;  1K73 V;  3CPW T;  4UY8 X;  3ABQ A;  1YJ9 U;  2QEZ A;  1YIJ U;  2QEX U;  1JJ2 T;  3I56 U;  1JJD A;  1S72 U;  3G71 U;  3CCU U;  3CD6 U;  3I55 U;  1VQ6 U;  1VQ9 U;  3CCV U;  3CCL U;  3OW2 T;  2OTJ U;  3G4S U;  3CME U;  1NJI V;  2OTL U;  1VQ8 U;  3G6E U;  3ABS A;  1VQM U;  3ABO A;  1VQ7 U;  3ANY A;  3CCQ U;  3ABR A;  1N8R V;  1VQL U;  3CMA U;  1QVG T;  1KQS T;  1Q7Y V;  3CC2 U;  1KC8 V;  1VQ5 U;  1Q82 V;  1VQK U;  1YI2 U;  5DM6 U;  1VQ4 U;  5H1S Y;  1VQP U;  3CC7 U;  2JZ6 A;  5AN9 G;  3CXC T;  5MLC Y;  1KD1 V;  1K9M V;  1YJN U;  1M90 V;  3CC4 U;  2QA4 U;  1VQO U;  1QVF T;  3CCM U;  1VQN U;  1Q86 V;  3CCR U;  3CCJ U;  3AO0 A;  1YJW U;  3J7Z X;  1W2B T;  1K8A V;  3CCS U;  1YIT U;  1Q81 V;  1M1K V;  3CCE U; 
#chains in the Genus database with same CATH homology
 3CXC T;  1YHQ U;  1KD1 V;  3CCV U;  3CCL U;  1K9M V;  1YJN U;  1K73 V;  3CCQ U;  1N8R V;  1VQL U;  1M90 V;  3CMA U;  3CC4 U;  2QA4 U;  3CPW T;  3OW2 T;  1VQO U;  1QVG T;  3G4S U;  1KQS T;  1Q7Y V;  2OTJ U;  1QVF T;  3CCM U;  3CME U;  1NJI V;  1YJ9 U;  3CC2 U;  1KC8 V;  2OTL U;  1VQ8 U;  1VQ5 U;  1VQN U;  1YIJ U;  2QEX U;  1Q82 V;  1JJ2 T;  1Q86 V;  1VQK U;  3CCR U;  1YI2 U;  3I56 U;  3CCJ U;  1JJD A;  3G6E U;  1S72 U;  3G71 U;  3CCU U;  3CD6 U;  1YJW U;  1VQ4 U;  1VQM U;  1W2B T;  1K8A V;  1M1K V;  3I55 U;  1VQ6 U;  3CCS U;  1VQP U;  1YIT U;  1VQ9 U;  1Q81 V;  3CC7 U;  1VQ7 U;  5AN9 G;  3CCE U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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