3G4SU

Co-crystal structure of tiamulin bound to the large ribosomal subunit
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule keywords 23S ribosomal RNA
molecule tags Ribosome
total genus 6
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2009-02-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3g4sU00
3G4SU 3CMAU 1KQST 3CPWT 2OTLU 1Q7YV 3I55U 2OTJU 1VQ9U 3OW2T 1M1KV 3CCQU 1W2BT 1Q81V 3CD6U 3CXCT 3CCVU 3CCSU 1NJIV 3CCJU 1KC8V 1KD1V 1VQOU 3CCRU 3CC4U 1YJWU 1M90V 1QVGT 1Q82V 3CC7U 3G71U 1YHQU 1VQKU 1K8AV 1VQ4U 3CMEU 1VQ5U 1VQ6U 1VQNU 1YJ9U 2QA4U 1YITU 1VQ7U 1Q86V 1JJ2T 1N8RV 1K9MV 2QEXU 3CCMU 3CC2U 1YIJU 1VQMU 1YI2U 1K73V 3G6EU 3CCUU 1VQ8U 1QVFT 1VQLU 3I56U 1YJNU 5AN9G 1S72U 1VQPU 3CCEU 3CCLU
chains in the Genus database with same CATH superfamily
1KQST 2OTJU 1M1KV 3OW2T 3CCVU 3CCSU 3CC7U 3G71U 1VQ5U 2QA4U 3ABQA 2QEXU 3G6EU 3CCUU 1VQLU 1YJNU 1S72U 3CCEU 3ABSA 3CPWT 1VQ9U 1W2BT 3CD6U 1KD1V 1YJWU 3CMEU 1VQNU 1VQ6U 1YJ9U 4UY8X 1Q86V 1JJ2T 1N8RV 1K9MV 1VQMU 1YI2U 1QVFT 5AN9G 3G4SU 2OTLU 1Q7YV 3CXCT 1JJDA 3CCJU 1VQOU 1QVGT 1Q82V 2JZ6A 1YHQU 1VQ7U 5MLCY 3ANYA 3AO0A 3ABOA 3J7ZX 3I56U 2QEZA 1VQPU 1K8AV 3CMAU 3I55U 5H1SY 3CCQU 1Q81V 1NJIV 1KC8V 3ABRA 3CCRU 3CC4U 1M90V 1VQKU 1VQ4U 1YITU 3CC2U 3CCMU 1YIJU 1K73V 1VQ8U 5DM6U 3CCLU
chains in the Genus database with same CATH topology
3G4SU 3CMAU 1KQST 3CPWT 2OTLU 1Q7YV 3I55U 2OTJU 1VQ9U 3OW2T 1M1KV 3CCQU 1W2BT 1Q81V 3CD6U 3CXCT 1JJDA 3CCSU 3CCVU 3CCJU 1NJIV 1KC8V 1KD1V 1VQOU 3CCRU 3CC4U 1YJWU 1M90V 1QVGT 1Q82V 3CC7U 3G71U 1YHQU 1VQKU 1K8AV 1VQ4U 3CMEU 1VQ5U 1VQ6U 1VQNU 1YJ9U 2QA4U 1YITU 1VQ7U 1Q86V 1JJ2T 1N8RV 1K9MV 2QEXU 3CCMU 3CC2U 1YIJU 1VQMU 1YI2U 1K73V 3G6EU 3CCUU 1VQ8U 1QVFT 1VQLU 3I56U 1YJNU 5AN9G 1S72U 1VQPU 3CCEU 3CCLU
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G4S U;  3CMA U;  1KQS T;  3CPW T;  2OTL U;  1Q7Y V;  3I55 U;  2OTJ U;  1VQ9 U;  3OW2 T;  1M1K V;  3CCQ U;  1W2B T;  1Q81 V;  3CD6 U;  3CXC T;  3CCV U;  3CCS U;  1NJI V;  3CCJ U;  1KC8 V;  1KD1 V;  1VQO U;  3CCR U;  3CC4 U;  1YJW U;  1M90 V;  1QVG T;  1Q82 V;  3CC7 U;  3G71 U;  1YHQ U;  1VQK U;  1K8A V;  1VQ4 U;  3CME U;  1VQ5 U;  1VQ6 U;  1VQN U;  1YJ9 U;  2QA4 U;  1YIT U;  1VQ7 U;  1Q86 V;  1JJ2 T;  1N8R V;  1K9M V;  2QEX U;  3CCM U;  3CC2 U;  1YIJ U;  1VQM U;  1YI2 U;  1K73 V;  3G6E U;  3CCU U;  1VQ8 U;  1QVF T;  1VQL U;  3I56 U;  1YJN U;  5AN9 G;  1S72 U;  1VQP U;  3CCE U;  3CCL U; 
#chains in the Genus database with same CATH topology
 1KQS T;  2OTJ U;  1M1K V;  3OW2 T;  3CCV U;  3CCS U;  3CC7 U;  3G71 U;  1VQ5 U;  2QA4 U;  3ABQ A;  2QEX U;  3G6E U;  3CCU U;  1VQL U;  1YJN U;  1S72 U;  3CCE U;  3ABS A;  3CPW T;  1VQ9 U;  1W2B T;  3CD6 U;  1KD1 V;  1YJW U;  3CME U;  1VQN U;  1VQ6 U;  1YJ9 U;  4UY8 X;  1Q86 V;  1JJ2 T;  1N8R V;  1K9M V;  1VQM U;  1YI2 U;  1QVF T;  5AN9 G;  3G4S U;  2OTL U;  1Q7Y V;  3CXC T;  1JJD A;  3CCJ U;  1VQO U;  1QVG T;  1Q82 V;  2JZ6 A;  1YHQ U;  1VQ7 U;  5MLC Y;  3ANY A;  3AO0 A;  3ABO A;  3J7Z X;  3I56 U;  2QEZ A;  1VQP U;  1K8A V;  3CMA U;  3I55 U;  5H1S Y;  3CCQ U;  1Q81 V;  1NJI V;  1KC8 V;  3ABR A;  3CCR U;  3CC4 U;  1M90 V;  1VQK U;  1VQ4 U;  1YIT U;  3CC2 U;  3CCM U;  1YIJ U;  1K73 V;  1VQ8 U;  5DM6 U;  3CCL U; 
#chains in the Genus database with same CATH homology
 3G4S U;  3CMA U;  1KQS T;  3CPW T;  2OTL U;  1Q7Y V;  3I55 U;  2OTJ U;  1VQ9 U;  3OW2 T;  1M1K V;  3CCQ U;  1W2B T;  1Q81 V;  3CD6 U;  3CXC T;  1JJD A;  3CCS U;  3CCV U;  3CCJ U;  1NJI V;  1KC8 V;  1KD1 V;  1VQO U;  3CCR U;  3CC4 U;  1YJW U;  1M90 V;  1QVG T;  1Q82 V;  3CC7 U;  3G71 U;  1YHQ U;  1VQK U;  1K8A V;  1VQ4 U;  3CME U;  1VQ5 U;  1VQ6 U;  1VQN U;  1YJ9 U;  2QA4 U;  1YIT U;  1VQ7 U;  1Q86 V;  1JJ2 T;  1N8R V;  1K9M V;  2QEX U;  3CCM U;  3CC2 U;  1YIJ U;  1VQM U;  1YI2 U;  1K73 V;  3G6E U;  3CCU U;  1VQ8 U;  1QVF T;  1VQL U;  3I56 U;  1YJN U;  5AN9 G;  1S72 U;  1VQP U;  3CCE U;  3CCL U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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