3G4SU

Co-crystal structure of tiamulin bound to the large ribosomal subunit
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 6
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2009-02-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3g4sU00
3OW2T 1VQOU 2QA4U 1S72U 3CC4U 1M90V 1QVGT 1YI2U 1YJNU 1VQPU 3CPWT 1Q86V 3I56U 3CCRU 1N8RV 3CXCT 1KC8V 1QVFT 1M1KV 1VQNU 1VQ7U 1VQ5U 1Q81V 1VQ9U 1VQ4U 3CMAU 3I55U 2QEXU 1K73V 1VQLU 3G71U 1YJWU 3CD6U 3CCEU 3CCVU 5AN9G 3CCLU 1Q7YV 3CMEU 1K8AV 3CCQU 1JJ2T 2OTLU 1K9MV 3CC7U 1VQKU 3CC2U 1VQMU 3G6EU 1YITU 3CCSU 1VQ6U 2OTJU 1YIJU 3CCMU 1KD1V 3CCUU 1YHQU 1W2BT 3CCJU 1VQ8U 1NJIV 1Q82V 3G4SU 1KQST 1YJ9U
chains in the Genus database with same CATH superfamily
3OW2T 2QA4U 3CC4U 1VQ7U 1Q81V 2QEXU 1YJWU 3CCQU 3J7ZX 3CCMU 1VQ8U 1Q82V 1YJ9U 3ABRA 1YJNU 1Q86V 3ABQA 1VQ9U 1VQ4U 2JZ6A 1K73V 1VQLU 5AN9G 1Q7YV 1K8AV 1JJ2T 2OTLU 2QEZA 3AO0A 3ANYA 1YITU 5DM6U 1W2BT 1YHQU 1JJDA 5H1SY 1N8RV 1VQOU 1S72U 1M90V 1YI2U 1VQPU 1KC8V 3ABSA 1VQ5U 3I55U 3CCVU 3CMEU 1VQ6U 1YIJU 1KD1V 3CCUU 1QVGT 3CPWT 3I56U 3CCRU 3CXCT 1QVFT 1M1KV 1VQNU 3CMAU 3G71U 3CD6U 3CCEU 3CC7U 3CCLU 1K9MV 1VQKU 3CC2U 3ABOA 5MLCY 3G6EU 3CCSU 1VQMU 2OTJU 3CCJU 1NJIV 4UY8X 3G4SU 1KQST
chains in the Genus database with same CATH topology
3OW2T 1VQOU 2QA4U 1S72U 3CC4U 1M90V 1QVGT 1YI2U 1YJNU 1VQPU 3CPWT 1Q86V 3I56U 3CCRU 1N8RV 3CXCT 1KC8V 1QVFT 1M1KV 1VQNU 1VQ7U 1VQ5U 1Q81V 1VQ9U 1VQ4U 3CMAU 3I55U 2QEXU 1K73V 1VQLU 3G71U 1YJWU 3CD6U 3CCEU 3CCVU 5AN9G 3CCLU 1Q7YV 3CMEU 1K8AV 3CCQU 1JJ2T 2OTLU 1K9MV 3CC7U 1VQKU 3CC2U 1VQMU 3G6EU 1YITU 3CCSU 1VQ6U 2OTJU 1YIJU 3CCMU 1KD1V 3CCUU 1YHQU 1W2BT 3CCJU 1VQ8U 1JJDA 1NJIV 1Q82V 3G4SU 1KQST 1YJ9U
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OW2 T;  1VQO U;  2QA4 U;  1S72 U;  3CC4 U;  1M90 V;  1QVG T;  1YI2 U;  1YJN U;  1VQP U;  3CPW T;  1Q86 V;  3I56 U;  3CCR U;  1N8R V;  3CXC T;  1KC8 V;  1QVF T;  1M1K V;  1VQN U;  1VQ7 U;  1VQ5 U;  1Q81 V;  1VQ9 U;  1VQ4 U;  3CMA U;  3I55 U;  2QEX U;  1K73 V;  1VQL U;  3G71 U;  1YJW U;  3CD6 U;  3CCE U;  3CCV U;  5AN9 G;  3CCL U;  1Q7Y V;  3CME U;  1K8A V;  3CCQ U;  1JJ2 T;  2OTL U;  1K9M V;  3CC7 U;  1VQK U;  3CC2 U;  1VQM U;  3G6E U;  1YIT U;  3CCS U;  1VQ6 U;  2OTJ U;  1YIJ U;  3CCM U;  1KD1 V;  3CCU U;  1YHQ U;  1W2B T;  3CCJ U;  1VQ8 U;  1NJI V;  1Q82 V;  3G4S U;  1KQS T;  1YJ9 U; 
#chains in the Genus database with same CATH topology
 3OW2 T;  2QA4 U;  3CC4 U;  1VQ7 U;  1Q81 V;  2QEX U;  1YJW U;  3CCQ U;  3J7Z X;  3CCM U;  1VQ8 U;  1Q82 V;  1YJ9 U;  3ABR A;  1YJN U;  1Q86 V;  3ABQ A;  1VQ9 U;  1VQ4 U;  2JZ6 A;  1K73 V;  1VQL U;  5AN9 G;  1Q7Y V;  1K8A V;  1JJ2 T;  2OTL U;  2QEZ A;  3AO0 A;  3ANY A;  1YIT U;  5DM6 U;  1W2B T;  1YHQ U;  1JJD A;  5H1S Y;  1N8R V;  1VQO U;  1S72 U;  1M90 V;  1YI2 U;  1VQP U;  1KC8 V;  3ABS A;  1VQ5 U;  3I55 U;  3CCV U;  3CME U;  1VQ6 U;  1YIJ U;  1KD1 V;  3CCU U;  1QVG T;  3CPW T;  3I56 U;  3CCR U;  3CXC T;  1QVF T;  1M1K V;  1VQN U;  3CMA U;  3G71 U;  3CD6 U;  3CCE U;  3CC7 U;  3CCL U;  1K9M V;  1VQK U;  3CC2 U;  3ABO A;  5MLC Y;  3G6E U;  3CCS U;  1VQM U;  2OTJ U;  3CCJ U;  1NJI V;  4UY8 X;  3G4S U;  1KQS T; 
#chains in the Genus database with same CATH homology
 3OW2 T;  1VQO U;  2QA4 U;  1S72 U;  3CC4 U;  1M90 V;  1QVG T;  1YI2 U;  1YJN U;  1VQP U;  3CPW T;  1Q86 V;  3I56 U;  3CCR U;  1N8R V;  3CXC T;  1KC8 V;  1QVF T;  1M1K V;  1VQN U;  1VQ7 U;  1VQ5 U;  1Q81 V;  1VQ9 U;  1VQ4 U;  3CMA U;  3I55 U;  2QEX U;  1K73 V;  1VQL U;  3G71 U;  1YJW U;  3CD6 U;  3CCE U;  3CCV U;  5AN9 G;  3CCL U;  1Q7Y V;  3CME U;  1K8A V;  3CCQ U;  1JJ2 T;  2OTL U;  1K9M V;  3CC7 U;  1VQK U;  3CC2 U;  1VQM U;  3G6E U;  1YIT U;  3CCS U;  1VQ6 U;  2OTJ U;  1YIJ U;  3CCM U;  1KD1 V;  3CCU U;  1YHQ U;  1W2B T;  3CCJ U;  1VQ8 U;  1JJD A;  1NJI V;  1Q82 V;  3G4S U;  1KQS T;  1YJ9 U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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