3G4SU

Co-crystal structure of tiamulin bound to the large ribosomal subunit
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule keywords 23S ribosomal RNA
molecule tags Ribosome
total genus 6
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2009-02-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3g4sU00
3CCRU 3CCUU 5AN9G 1Q7YV 1M90V 1VQ8U 1VQNU 3CCMU 3CC7U 3CCLU 1YJ9U 1VQ7U 1JJ2T 1VQLU 1N8RV 3CMEU 3CCVU 1VQ4U 3CC2U 2QEXU 1KQST 3CC4U 1NJIV 1K8AV 3CXCT 3CPWT 3CCEU 3CMAU 1VQMU 1YIJU 1YHQU 1S72U 1KD1V 1VQ6U 3CCQU 1YJWU 1YJNU 2OTJU 1QVFT 1Q82V 1W2BT 1YITU 2OTLU 1K9MV 1QVGT 1Q81V 3CCJU 1VQOU 1VQ5U 3G71U 3I56U 1Q86V 1YI2U 3OW2T 1KC8V 3I55U 1M1KV 3G6EU 1VQ9U 3CCSU 1K73V 1VQKU 2QA4U 3CD6U 3G4SU 1VQPU
chains in the Genus database with same CATH superfamily
3CCRU 1Q7YV 3CC7U 1VQ7U 1JJ2T 2JZ6A 1VQLU 2QEZA 1KQST 1NJIV 3CXCT 3CPWT 3CCEU 3CMAU 1VQMU 1YIJU 5DM6U 1YJWU 1YJNU 3ANYA 1VQOU 3ABSA 3I55U 3G6EU 3CCSU 3CD6U 1VQPU 1VQNU 3CMEU 3CCVU 5MLCY 3CC4U 3CCQU 2OTJU 1QVFT 1W2BT 1QVGT 1VQ5U 3G71U 3I56U 3ABRA 1Q86V 3CCUU 1M90V 1JJDA 3CCMU 3AO0A 3CCLU 3CC2U 2QEXU 1K8AV 1S72U 3ABOA 1Q82V 2OTLU 1K9MV 1Q81V 5H1SY 1YI2U 1KC8V 1M1KV 1VQKU 2QA4U 5AN9G 1VQ8U 1YJ9U 1N8RV 1VQ4U 1KD1V 1YHQU 1VQ6U 1YITU 4UY8X 3CCJU 3J7ZX 3ABQA 3OW2T 1VQ9U 1K73V 3G4SU
chains in the Genus database with same CATH topology
3CCRU 3CCUU 5AN9G 1Q7YV 1M90V 1VQ8U 1VQNU 1JJDA 3CCMU 3CC7U 3CCLU 1YJ9U 1VQ7U 1JJ2T 1VQLU 1N8RV 3CMEU 3CCVU 1VQ4U 3CC2U 2QEXU 1KQST 3CC4U 1NJIV 1K8AV 3CXCT 3CPWT 3CCEU 3CMAU 1VQMU 1YIJU 1YHQU 1S72U 1KD1V 1VQ6U 3CCQU 1YJWU 1YJNU 2OTJU 1QVFT 1Q82V 1W2BT 1YITU 2OTLU 1K9MV 1QVGT 1Q81V 3CCJU 1VQOU 1VQ5U 3G71U 3I56U 1Q86V 1YI2U 3OW2T 1KC8V 3I55U 1M1KV 3G6EU 1VQ9U 3CCSU 1K73V 1VQKU 2QA4U 3CD6U 3G4SU 1VQPU
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCR U;  3CCU U;  5AN9 G;  1Q7Y V;  1M90 V;  1VQ8 U;  1VQN U;  3CCM U;  3CC7 U;  3CCL U;  1YJ9 U;  1VQ7 U;  1JJ2 T;  1VQL U;  1N8R V;  3CME U;  3CCV U;  1VQ4 U;  3CC2 U;  2QEX U;  1KQS T;  3CC4 U;  1NJI V;  1K8A V;  3CXC T;  3CPW T;  3CCE U;  3CMA U;  1VQM U;  1YIJ U;  1YHQ U;  1S72 U;  1KD1 V;  1VQ6 U;  3CCQ U;  1YJW U;  1YJN U;  2OTJ U;  1QVF T;  1Q82 V;  1W2B T;  1YIT U;  2OTL U;  1K9M V;  1QVG T;  1Q81 V;  3CCJ U;  1VQO U;  1VQ5 U;  3G71 U;  3I56 U;  1Q86 V;  1YI2 U;  3OW2 T;  1KC8 V;  3I55 U;  1M1K V;  3G6E U;  1VQ9 U;  3CCS U;  1K73 V;  1VQK U;  2QA4 U;  3CD6 U;  3G4S U;  1VQP U; 
#chains in the Genus database with same CATH topology
 3CCR U;  1Q7Y V;  3CC7 U;  1VQ7 U;  1JJ2 T;  2JZ6 A;  1VQL U;  2QEZ A;  1KQS T;  1NJI V;  3CXC T;  3CPW T;  3CCE U;  3CMA U;  1VQM U;  1YIJ U;  5DM6 U;  1YJW U;  1YJN U;  3ANY A;  1VQO U;  3ABS A;  3I55 U;  3G6E U;  3CCS U;  3CD6 U;  1VQP U;  1VQN U;  3CME U;  3CCV U;  5MLC Y;  3CC4 U;  3CCQ U;  2OTJ U;  1QVF T;  1W2B T;  1QVG T;  1VQ5 U;  3G71 U;  3I56 U;  3ABR A;  1Q86 V;  3CCU U;  1M90 V;  1JJD A;  3CCM U;  3AO0 A;  3CCL U;  3CC2 U;  2QEX U;  1K8A V;  1S72 U;  3ABO A;  1Q82 V;  2OTL U;  1K9M V;  1Q81 V;  5H1S Y;  1YI2 U;  1KC8 V;  1M1K V;  1VQK U;  2QA4 U;  5AN9 G;  1VQ8 U;  1YJ9 U;  1N8R V;  1VQ4 U;  1KD1 V;  1YHQ U;  1VQ6 U;  1YIT U;  4UY8 X;  3CCJ U;  3J7Z X;  3ABQ A;  3OW2 T;  1VQ9 U;  1K73 V;  3G4S U; 
#chains in the Genus database with same CATH homology
 3CCR U;  3CCU U;  5AN9 G;  1Q7Y V;  1M90 V;  1VQ8 U;  1VQN U;  1JJD A;  3CCM U;  3CC7 U;  3CCL U;  1YJ9 U;  1VQ7 U;  1JJ2 T;  1VQL U;  1N8R V;  3CME U;  3CCV U;  1VQ4 U;  3CC2 U;  2QEX U;  1KQS T;  3CC4 U;  1NJI V;  1K8A V;  3CXC T;  3CPW T;  3CCE U;  3CMA U;  1VQM U;  1YIJ U;  1YHQ U;  1S72 U;  1KD1 V;  1VQ6 U;  3CCQ U;  1YJW U;  1YJN U;  2OTJ U;  1QVF T;  1Q82 V;  1W2B T;  1YIT U;  2OTL U;  1K9M V;  1QVG T;  1Q81 V;  3CCJ U;  1VQO U;  1VQ5 U;  3G71 U;  3I56 U;  1Q86 V;  1YI2 U;  3OW2 T;  1KC8 V;  3I55 U;  1M1K V;  3G6E U;  1VQ9 U;  3CCS U;  1K73 V;  1VQK U;  2QA4 U;  3CD6 U;  3G4S U;  1VQP U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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