3G6EU

Co-crystal structure of homoharringtonine bound to the large ribosomal subunit
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule keywords 23S ribosomal RNA
total genus 10
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2009-02-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3g6eU00
1VQ6U 1JJ2T 1VQNU 3CCMU 1KC8V 3CC4U 3CPWT 3CXCT 1VQ9U 2QA4U 1YI2U 1YHQU 3CMAU 2OTLU 1KQST 1S72U 3CD6U 3CCUU 1VQKU 1VQPU 3CCEU 1VQ7U 1K8AV 1K9MV 1VQ4U 3CC7U 1VQOU 3CCRU 1Q82V 1NJIV 3CCLU 1KD1V 1M1KV 1VQLU 3OW2T 1YJNU 3I56U 3CCVU 3CCSU 3G4SU 1K73V 1YJ9U 1W2BT 1Q81V 3CMEU 1Q7YV 3CCJU 1YITU 2OTJU 1YJWU 1N8RV 1M90V 1YIJU 3CCQU 5AN9G 1QVGT 3G6EU 1Q86V 1QVFT 1VQ8U 3CC2U 3I55U 2QEXU 3G71U 1VQ5U 1VQMU
chains in the Genus database with same CATH superfamily
1VQNU 3CCMU 1VQ9U 2QA4U 1YI2U 3CD6U 1VQKU 1VQPU 3ABOA 3CCEU 3CCRU 1KD1V 1YJNU 5MLCY 3I56U 1K73V 3ABSA 2OTJU 1M90V 5AN9G 3G6EU 1VQ8U 3CC2U 4UY8X 3J7ZX 1JJ2T 1KC8V 3CPWT 2OTLU 3ABQA 5DM6U 1VQ7U 1K9MV 3CC7U 1Q82V 3OW2T 3CCVU 1JJDA 1Q86V 3I55U 2QEXU 1VQMU 1VQ6U 3CC4U 3CXCT 2JZ6A 1K8AV 1VQ4U 1NJIV 3CCLU 1M1KV 1VQLU 2QEZA 3CCSU 3G4SU 1YJ9U 1W2BT 1Q81V 3CMEU 1YITU 1YJWU 1N8RV 5H1SY 1QVGT 3G71U 1VQ5U 1YHQU 3CMAU 1KQST 1S72U 3CCUU 1VQOU 3ANYA 1Q7YV 3CCJU 1YIJU 3CCQU 3ABRA 1QVFT 3AO0A
chains in the Genus database with same CATH topology
1VQ6U 1JJ2T 1VQNU 3CCMU 1KC8V 3CC4U 3CPWT 3CXCT 1VQ9U 2QA4U 1YI2U 1YHQU 3CMAU 2OTLU 1KQST 1S72U 3CD6U 3CCUU 1VQKU 1VQPU 3CCEU 1VQ7U 1K8AV 1K9MV 1VQ4U 3CC7U 1VQOU 3CCRU 1Q82V 1NJIV 3CCLU 1KD1V 1M1KV 1VQLU 3OW2T 1YJNU 3I56U 3CCVU 3CCSU 3G4SU 1K73V 1YJ9U 1W2BT 1JJDA 1Q81V 3CMEU 1Q7YV 3CCJU 1YITU 2OTJU 1YJWU 1N8RV 1M90V 1YIJU 3CCQU 5AN9G 1QVGT 3G6EU 1Q86V 1QVFT 1VQ8U 3CC2U 3I55U 2QEXU 3G71U 1VQ5U 1VQMU
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ6 U;  1JJ2 T;  1VQN U;  3CCM U;  1KC8 V;  3CC4 U;  3CPW T;  3CXC T;  1VQ9 U;  2QA4 U;  1YI2 U;  1YHQ U;  3CMA U;  2OTL U;  1KQS T;  1S72 U;  3CD6 U;  3CCU U;  1VQK U;  1VQP U;  3CCE U;  1VQ7 U;  1K8A V;  1K9M V;  1VQ4 U;  3CC7 U;  1VQO U;  3CCR U;  1Q82 V;  1NJI V;  3CCL U;  1KD1 V;  1M1K V;  1VQL U;  3OW2 T;  1YJN U;  3I56 U;  3CCV U;  3CCS U;  3G4S U;  1K73 V;  1YJ9 U;  1W2B T;  1Q81 V;  3CME U;  1Q7Y V;  3CCJ U;  1YIT U;  2OTJ U;  1YJW U;  1N8R V;  1M90 V;  1YIJ U;  3CCQ U;  5AN9 G;  1QVG T;  3G6E U;  1Q86 V;  1QVF T;  1VQ8 U;  3CC2 U;  3I55 U;  2QEX U;  3G71 U;  1VQ5 U;  1VQM U; 
#chains in the Genus database with same CATH topology
 1VQN U;  3CCM U;  1VQ9 U;  2QA4 U;  1YI2 U;  3CD6 U;  1VQK U;  1VQP U;  3ABO A;  3CCE U;  3CCR U;  1KD1 V;  1YJN U;  5MLC Y;  3I56 U;  1K73 V;  3ABS A;  2OTJ U;  1M90 V;  5AN9 G;  3G6E U;  1VQ8 U;  3CC2 U;  4UY8 X;  3J7Z X;  1JJ2 T;  1KC8 V;  3CPW T;  2OTL U;  3ABQ A;  5DM6 U;  1VQ7 U;  1K9M V;  3CC7 U;  1Q82 V;  3OW2 T;  3CCV U;  1JJD A;  1Q86 V;  3I55 U;  2QEX U;  1VQM U;  1VQ6 U;  3CC4 U;  3CXC T;  2JZ6 A;  1K8A V;  1VQ4 U;  1NJI V;  3CCL U;  1M1K V;  1VQL U;  2QEZ A;  3CCS U;  3G4S U;  1YJ9 U;  1W2B T;  1Q81 V;  3CME U;  1YIT U;  1YJW U;  1N8R V;  5H1S Y;  1QVG T;  3G71 U;  1VQ5 U;  1YHQ U;  3CMA U;  1KQS T;  1S72 U;  3CCU U;  1VQO U;  3ANY A;  1Q7Y V;  3CCJ U;  1YIJ U;  3CCQ U;  3ABR A;  1QVF T;  3AO0 A; 
#chains in the Genus database with same CATH homology
 1VQ6 U;  1JJ2 T;  1VQN U;  3CCM U;  1KC8 V;  3CC4 U;  3CPW T;  3CXC T;  1VQ9 U;  2QA4 U;  1YI2 U;  1YHQ U;  3CMA U;  2OTL U;  1KQS T;  1S72 U;  3CD6 U;  3CCU U;  1VQK U;  1VQP U;  3CCE U;  1VQ7 U;  1K8A V;  1K9M V;  1VQ4 U;  3CC7 U;  1VQO U;  3CCR U;  1Q82 V;  1NJI V;  3CCL U;  1KD1 V;  1M1K V;  1VQL U;  3OW2 T;  1YJN U;  3I56 U;  3CCV U;  3CCS U;  3G4S U;  1K73 V;  1YJ9 U;  1W2B T;  1JJD A;  1Q81 V;  3CME U;  1Q7Y V;  3CCJ U;  1YIT U;  2OTJ U;  1YJW U;  1N8R V;  1M90 V;  1YIJ U;  3CCQ U;  5AN9 G;  1QVG T;  3G6E U;  1Q86 V;  1QVF T;  1VQ8 U;  3CC2 U;  3I55 U;  2QEX U;  3G71 U;  1VQ5 U;  1VQM U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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