3G6EU

Co-crystal structure of homoharringtonine bound to the large ribosomal subunit
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule keywords 23S ribosomal RNA
molecule tags Ribosome
total genus 10
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2009-02-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3g6eU00
3OW2T 3CCSU 1YJNU 1NJIV 1QVFT 1YJWU 1Q81V 2OTJU 5AN9G 3CMAU 1JJ2T 3CCQU 3CXCT 3CCUU 1QVGT 3CC2U 1M90V 3CMEU 1VQPU 1KD1V 1VQ4U 3I56U 1W2BT 1VQ7U 3CC4U 3CPWT 3CCMU 1M1KV 1VQ5U 1VQ6U 3CD6U 1YHQU 1K8AV 1VQKU 1YI2U 2QEXU 1VQMU 3G71U 3CCRU 1YIJU 3CCLU 3CCEU 1VQ9U 1VQ8U 1Q86V 1VQOU 3CCVU 1S72U 2OTLU 2QA4U 1VQNU 3CCJU 3I55U 1N8RV 1K9MV 1YITU 1K73V 1Q82V 1KC8V 3CC7U 3G4SU 1Q7YV 1VQLU 1KQST 3G6EU 1YJ9U
chains in the Genus database with same CATH superfamily
1QVFT 1YJWU 1JJDA 5AN9G 5MLCY 3CXCT 3CCUU 1VQ7U 2QEXU 1VQMU 3G71U 1YIJU 1VQ8U 1Q86V 1VQOU 2JZ6A 4UY8X 3I55U 1N8RV 1K9MV 1K73V 1YJ9U 3CCQU 1QVGT 1VQPU 1VQ4U 3I56U 3CPWT 1VQ5U 1K8AV 1YI2U 3ABRA 3CCLU 3CCVU 1S72U 3ABQA 1YITU 3G4SU 1VQLU 3G6EU 3OW2T 3CCSU 1YJNU 1Q81V 3ANYA 3ABSA 3ABOA 1VQ6U 3CC4U 1M1KV 3CD6U 1YHQU 5DM6U 3CCEU 1VQ9U 2OTLU 2QEZA 3CCJU 1KC8V 5H1SY 1NJIV 2OTJU 3CMAU 1JJ2T 3CC2U 3J7ZX 1M90V 3CMEU 1KD1V 1W2BT 3AO0A 3CCMU 1VQKU 3CCRU 1VQNU 2QA4U 1Q82V 3CC7U 1Q7YV 1KQST
chains in the Genus database with same CATH topology
3OW2T 3CCSU 1YJNU 1NJIV 1QVFT 1YJWU 1Q81V 2OTJU 1JJDA 5AN9G 3CMAU 1JJ2T 3CCQU 3CXCT 3CCUU 1QVGT 3CC2U 1M90V 3CMEU 1VQPU 1KD1V 1VQ4U 3I56U 1W2BT 1VQ7U 3CC4U 3CPWT 3CCMU 1M1KV 1VQ5U 1VQ6U 3CD6U 1YHQU 1K8AV 1VQKU 1YI2U 2QEXU 1VQMU 3G71U 3CCRU 1YIJU 3CCLU 3CCEU 1VQ9U 1VQ8U 1Q86V 1VQOU 3CCVU 1S72U 2OTLU 2QA4U 1VQNU 3CCJU 3I55U 1N8RV 1K9MV 1YITU 1K73V 1Q82V 1KC8V 3CC7U 3G4SU 1Q7YV 1VQLU 1KQST 3G6EU 1YJ9U
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OW2 T;  3CCS U;  1YJN U;  1NJI V;  1QVF T;  1YJW U;  1Q81 V;  2OTJ U;  5AN9 G;  3CMA U;  1JJ2 T;  3CCQ U;  3CXC T;  3CCU U;  1QVG T;  3CC2 U;  1M90 V;  3CME U;  1VQP U;  1KD1 V;  1VQ4 U;  3I56 U;  1W2B T;  1VQ7 U;  3CC4 U;  3CPW T;  3CCM U;  1M1K V;  1VQ5 U;  1VQ6 U;  3CD6 U;  1YHQ U;  1K8A V;  1VQK U;  1YI2 U;  2QEX U;  1VQM U;  3G71 U;  3CCR U;  1YIJ U;  3CCL U;  3CCE U;  1VQ9 U;  1VQ8 U;  1Q86 V;  1VQO U;  3CCV U;  1S72 U;  2OTL U;  2QA4 U;  1VQN U;  3CCJ U;  3I55 U;  1N8R V;  1K9M V;  1YIT U;  1K73 V;  1Q82 V;  1KC8 V;  3CC7 U;  3G4S U;  1Q7Y V;  1VQL U;  1KQS T;  3G6E U;  1YJ9 U; 
#chains in the Genus database with same CATH topology
 1QVF T;  1YJW U;  1JJD A;  5AN9 G;  5MLC Y;  3CXC T;  3CCU U;  1VQ7 U;  2QEX U;  1VQM U;  3G71 U;  1YIJ U;  1VQ8 U;  1Q86 V;  1VQO U;  2JZ6 A;  4UY8 X;  3I55 U;  1N8R V;  1K9M V;  1K73 V;  1YJ9 U;  3CCQ U;  1QVG T;  1VQP U;  1VQ4 U;  3I56 U;  3CPW T;  1VQ5 U;  1K8A V;  1YI2 U;  3ABR A;  3CCL U;  3CCV U;  1S72 U;  3ABQ A;  1YIT U;  3G4S U;  1VQL U;  3G6E U;  3OW2 T;  3CCS U;  1YJN U;  1Q81 V;  3ANY A;  3ABS A;  3ABO A;  1VQ6 U;  3CC4 U;  1M1K V;  3CD6 U;  1YHQ U;  5DM6 U;  3CCE U;  1VQ9 U;  2OTL U;  2QEZ A;  3CCJ U;  1KC8 V;  5H1S Y;  1NJI V;  2OTJ U;  3CMA U;  1JJ2 T;  3CC2 U;  3J7Z X;  1M90 V;  3CME U;  1KD1 V;  1W2B T;  3AO0 A;  3CCM U;  1VQK U;  3CCR U;  1VQN U;  2QA4 U;  1Q82 V;  3CC7 U;  1Q7Y V;  1KQS T; 
#chains in the Genus database with same CATH homology
 3OW2 T;  3CCS U;  1YJN U;  1NJI V;  1QVF T;  1YJW U;  1Q81 V;  2OTJ U;  1JJD A;  5AN9 G;  3CMA U;  1JJ2 T;  3CCQ U;  3CXC T;  3CCU U;  1QVG T;  3CC2 U;  1M90 V;  3CME U;  1VQP U;  1KD1 V;  1VQ4 U;  3I56 U;  1W2B T;  1VQ7 U;  3CC4 U;  3CPW T;  3CCM U;  1M1K V;  1VQ5 U;  1VQ6 U;  3CD6 U;  1YHQ U;  1K8A V;  1VQK U;  1YI2 U;  2QEX U;  1VQM U;  3G71 U;  3CCR U;  1YIJ U;  3CCL U;  3CCE U;  1VQ9 U;  1VQ8 U;  1Q86 V;  1VQO U;  3CCV U;  1S72 U;  2OTL U;  2QA4 U;  1VQN U;  3CCJ U;  3I55 U;  1N8R V;  1K9M V;  1YIT U;  1K73 V;  1Q82 V;  1KC8 V;  3CC7 U;  3G4S U;  1Q7Y V;  1VQL U;  1KQS T;  3G6E U;  1YJ9 U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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