3G6EU

Co-crystal structure of homoharringtonine bound to the large ribosomal subunit
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule keywords 23S ribosomal RNA
molecule tags Ribosome
total genus 10
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2009-02-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3g6eU00
3G71U 1YJWU 1KQST 3CPWT 1VQOU 3G4SU 1JJ2T 1VQ7U 1VQLU 1KC8V 5AN9G 1VQ8U 1QVFT 2QEXU 3CCUU 1QVGT 3G6EU 3CCSU 1NJIV 1S72U 3CC7U 1K9MV 1VQ6U 3CXCT 3CCRU 1W2BT 3CMEU 3CC2U 3CCJU 1Q86V 3CMAU 3I55U 1VQ5U 1VQ4U 3CCVU 3OW2T 1VQMU 1M90V 1YHQU 1YIJU 1VQ9U 1Q7YV 3CCMU 1VQPU 1Q81V 2OTLU 1VQKU 3CCQU 1M1KV 1N8RV 3CD6U 1YJNU 1KD1V 1YITU 1K8AV 1YI2U 2OTJU 1Q82V 3I56U 3CCLU 1YJ9U 1VQNU 1K73V 3CC4U 3CCEU 2QA4U
chains in the Genus database with same CATH superfamily
3G71U 1JJ2T 3CCUU 1QVGT 1NJIV 1VQ6U 3CC2U 3ANYA 3I55U 3CCVU 3CCMU 1Q81V 1YJNU 3ABOA 1K73V 3ABQA 1VQOU 1VQ7U 5AN9G 1VQ8U 2QEXU 3ABSA 1S72U 3CC7U 1Q86V 3CMAU 1VQ5U 1VQ4U 2JZ6A 1VQ9U 1Q7YV 1N8RV 1YITU 1K8AV 2OTJU 1Q82V 5H1SY 3CCLU 1VQNU 3CCEU 1QVFT 1KC8V 3G6EU 3CCRU 3CCJU 1VQMU 1YHQU 2OTLU 1VQKU 1KD1V 1YI2U 2QEZA 4UY8X 3I56U 3J7ZX 3ABRA 3CC4U 2QA4U 1JJDA 1YJWU 1KQST 3CPWT 3G4SU 1VQLU 3CCSU 1K9MV 3CXCT 1W2BT 3CMEU 3AO0A 3OW2T 1M90V 5DM6U 1YIJU 1VQPU 3CCQU 1M1KV 3CD6U 5MLCY 1YJ9U
chains in the Genus database with same CATH topology
3G71U 1YJWU 1KQST 3CPWT 1VQOU 3G4SU 1JJ2T 1VQ7U 1VQLU 1KC8V 5AN9G 1VQ8U 1QVFT 2QEXU 3CCUU 1QVGT 3G6EU 3CCSU 1NJIV 1S72U 3CC7U 1K9MV 1VQ6U 3CXCT 3CCRU 1W2BT 3CMEU 3CC2U 3CCJU 1Q86V 3CMAU 3I55U 1VQ5U 1VQ4U 3CCVU 3OW2T 1VQMU 1M90V 1YHQU 1YIJU 1VQ9U 1Q7YV 3CCMU 1VQPU 1Q81V 2OTLU 1VQKU 3CCQU 1M1KV 1N8RV 3CD6U 1YJNU 1KD1V 1YITU 1K8AV 1YI2U 2OTJU 1Q82V 3I56U 3CCLU 1YJ9U 1VQNU 1K73V 3CC4U 3CCEU 2QA4U 1JJDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G71 U;  1YJW U;  1KQS T;  3CPW T;  1VQO U;  3G4S U;  1JJ2 T;  1VQ7 U;  1VQL U;  1KC8 V;  5AN9 G;  1VQ8 U;  1QVF T;  2QEX U;  3CCU U;  1QVG T;  3G6E U;  3CCS U;  1NJI V;  1S72 U;  3CC7 U;  1K9M V;  1VQ6 U;  3CXC T;  3CCR U;  1W2B T;  3CME U;  3CC2 U;  3CCJ U;  1Q86 V;  3CMA U;  3I55 U;  1VQ5 U;  1VQ4 U;  3CCV U;  3OW2 T;  1VQM U;  1M90 V;  1YHQ U;  1YIJ U;  1VQ9 U;  1Q7Y V;  3CCM U;  1VQP U;  1Q81 V;  2OTL U;  1VQK U;  3CCQ U;  1M1K V;  1N8R V;  3CD6 U;  1YJN U;  1KD1 V;  1YIT U;  1K8A V;  1YI2 U;  2OTJ U;  1Q82 V;  3I56 U;  3CCL U;  1YJ9 U;  1VQN U;  1K73 V;  3CC4 U;  3CCE U;  2QA4 U; 
#chains in the Genus database with same CATH topology
 3G71 U;  1JJ2 T;  3CCU U;  1QVG T;  1NJI V;  1VQ6 U;  3CC2 U;  3ANY A;  3I55 U;  3CCV U;  3CCM U;  1Q81 V;  1YJN U;  3ABO A;  1K73 V;  3ABQ A;  1VQO U;  1VQ7 U;  5AN9 G;  1VQ8 U;  2QEX U;  3ABS A;  1S72 U;  3CC7 U;  1Q86 V;  3CMA U;  1VQ5 U;  1VQ4 U;  2JZ6 A;  1VQ9 U;  1Q7Y V;  1N8R V;  1YIT U;  1K8A V;  2OTJ U;  1Q82 V;  5H1S Y;  3CCL U;  1VQN U;  3CCE U;  1QVF T;  1KC8 V;  3G6E U;  3CCR U;  3CCJ U;  1VQM U;  1YHQ U;  2OTL U;  1VQK U;  1KD1 V;  1YI2 U;  2QEZ A;  4UY8 X;  3I56 U;  3J7Z X;  3ABR A;  3CC4 U;  2QA4 U;  1JJD A;  1YJW U;  1KQS T;  3CPW T;  3G4S U;  1VQL U;  3CCS U;  1K9M V;  3CXC T;  1W2B T;  3CME U;  3AO0 A;  3OW2 T;  1M90 V;  5DM6 U;  1YIJ U;  1VQP U;  3CCQ U;  1M1K V;  3CD6 U;  5MLC Y;  1YJ9 U; 
#chains in the Genus database with same CATH homology
 3G71 U;  1YJW U;  1KQS T;  3CPW T;  1VQO U;  3G4S U;  1JJ2 T;  1VQ7 U;  1VQL U;  1KC8 V;  5AN9 G;  1VQ8 U;  1QVF T;  2QEX U;  3CCU U;  1QVG T;  3G6E U;  3CCS U;  1NJI V;  1S72 U;  3CC7 U;  1K9M V;  1VQ6 U;  3CXC T;  3CCR U;  1W2B T;  3CME U;  3CC2 U;  3CCJ U;  1Q86 V;  3CMA U;  3I55 U;  1VQ5 U;  1VQ4 U;  3CCV U;  3OW2 T;  1VQM U;  1M90 V;  1YHQ U;  1YIJ U;  1VQ9 U;  1Q7Y V;  3CCM U;  1VQP U;  1Q81 V;  2OTL U;  1VQK U;  3CCQ U;  1M1K V;  1N8R V;  3CD6 U;  1YJN U;  1KD1 V;  1YIT U;  1K8A V;  1YI2 U;  2OTJ U;  1Q82 V;  3I56 U;  3CCL U;  1YJ9 U;  1VQN U;  1K73 V;  3CC4 U;  3CCE U;  2QA4 U;  1JJD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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