3G6EU

Co-crystal structure of homoharringtonine bound to the large ribosomal subunit
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 10
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2009-02-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3g6eU00
1QVFT 3CMEU 3I55U 3CCEU 1KC8V 1Q7YV 3CC7U 3CMAU 1KD1V 1YJWU 3CCSU 1VQPU 1VQLU 1VQ4U 2OTLU 1YJ9U 1VQNU 1Q86V 1M1KV 3CCQU 1M90V 3G6EU 3OW2T 1VQ7U 3G71U 1NJIV 2OTJU 1N8RV 2QA4U 3G4SU 1QVGT 3CCRU 1VQOU 1K8AV 1YHQU 1VQ5U 3I56U 3CD6U 3CCLU 3CC2U 1W2BT 3CC4U 1YI2U 3CCUU 1YJNU 3CCMU 2QEXU 1VQ9U 1VQMU 1K73V 1YITU 1VQKU 1VQ6U 3CXCT 1K9MV 3CPWT 1KQST 3CCVU 3CCJU 1YIJU 1JJ2T 1VQ8U 1Q81V 1Q82V 1S72U 5AN9G
chains in the Genus database with same CATH superfamily
3ABSA 3CCSU 1VQPU 1VQLU 2OTLU 1YJ9U 5H1SY 2JZ6A 1M90V 2OTJU 1VQOU 1K8AV 3CD6U 1W2BT 1YI2U 1YJNU 2QEXU 1VQ9U 3J7ZX 4UY8X 3CCVU 5AN9G 3CCEU 1KC8V 1KD1V 1VQ4U 1VQNU 1Q86V 3CCLU 5DM6U 1VQKU 1VQ6U 3AO0A 1Q81V 1Q82V 1QVFT 3CMEU 3I55U 1Q7YV 3CC7U 1YJWU 3ABQA 1M1KV 3ANYA 3G6EU 1NJIV 1VQ7U 2QA4U 3G4SU 3CCRU 3I56U 3CC2U 3CCUU 1VQMU 1K9MV 3CCJU 1YIJU 2QEZA 3CMAU 3ABOA 3CCQU 3OW2T 3G71U 1N8RV 1QVGT 1YHQU 3CC4U 3CCMU 1K73V 1YITU 5MLCY 3CXCT 1JJDA 3ABRA 3CPWT 1KQST 1JJ2T 1VQ8U 1VQ5U 1S72U
chains in the Genus database with same CATH topology
1QVFT 3CMEU 3I55U 3CCEU 1KC8V 1Q7YV 3CC7U 3CMAU 1KD1V 1YJWU 3CCSU 1VQPU 1VQLU 1VQ4U 2OTLU 1YJ9U 1VQNU 1Q86V 1M1KV 3CCQU 1M90V 3G6EU 3OW2T 1VQ7U 3G71U 1NJIV 2OTJU 1N8RV 2QA4U 3G4SU 1QVGT 3CCRU 1VQOU 1K8AV 1YHQU 1VQ5U 3I56U 3CD6U 3CCLU 3CC2U 1W2BT 3CC4U 1YI2U 3CCUU 1YJNU 3CCMU 2QEXU 1VQ9U 1VQMU 1K73V 1YITU 1VQKU 1VQ6U 3CXCT 1JJDA 1K9MV 3CPWT 1KQST 3CCVU 3CCJU 1YIJU 1JJ2T 1VQ8U 1Q81V 1Q82V 1S72U 5AN9G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QVF T;  3CME U;  3I55 U;  3CCE U;  1KC8 V;  1Q7Y V;  3CC7 U;  3CMA U;  1KD1 V;  1YJW U;  3CCS U;  1VQP U;  1VQL U;  1VQ4 U;  2OTL U;  1YJ9 U;  1VQN U;  1Q86 V;  1M1K V;  3CCQ U;  1M90 V;  3G6E U;  3OW2 T;  1VQ7 U;  3G71 U;  1NJI V;  2OTJ U;  1N8R V;  2QA4 U;  3G4S U;  1QVG T;  3CCR U;  1VQO U;  1K8A V;  1YHQ U;  1VQ5 U;  3I56 U;  3CD6 U;  3CCL U;  3CC2 U;  1W2B T;  3CC4 U;  1YI2 U;  3CCU U;  1YJN U;  3CCM U;  2QEX U;  1VQ9 U;  1VQM U;  1K73 V;  1YIT U;  1VQK U;  1VQ6 U;  3CXC T;  1K9M V;  3CPW T;  1KQS T;  3CCV U;  3CCJ U;  1YIJ U;  1JJ2 T;  1VQ8 U;  1Q81 V;  1Q82 V;  1S72 U;  5AN9 G; 
#chains in the Genus database with same CATH topology
 3ABS A;  3CCS U;  1VQP U;  1VQL U;  2OTL U;  1YJ9 U;  5H1S Y;  2JZ6 A;  1M90 V;  2OTJ U;  1VQO U;  1K8A V;  3CD6 U;  1W2B T;  1YI2 U;  1YJN U;  2QEX U;  1VQ9 U;  3J7Z X;  4UY8 X;  3CCV U;  5AN9 G;  3CCE U;  1KC8 V;  1KD1 V;  1VQ4 U;  1VQN U;  1Q86 V;  3CCL U;  5DM6 U;  1VQK U;  1VQ6 U;  3AO0 A;  1Q81 V;  1Q82 V;  1QVF T;  3CME U;  3I55 U;  1Q7Y V;  3CC7 U;  1YJW U;  3ABQ A;  1M1K V;  3ANY A;  3G6E U;  1NJI V;  1VQ7 U;  2QA4 U;  3G4S U;  3CCR U;  3I56 U;  3CC2 U;  3CCU U;  1VQM U;  1K9M V;  3CCJ U;  1YIJ U;  2QEZ A;  3CMA U;  3ABO A;  3CCQ U;  3OW2 T;  3G71 U;  1N8R V;  1QVG T;  1YHQ U;  3CC4 U;  3CCM U;  1K73 V;  1YIT U;  5MLC Y;  3CXC T;  1JJD A;  3ABR A;  3CPW T;  1KQS T;  1JJ2 T;  1VQ8 U;  1VQ5 U;  1S72 U; 
#chains in the Genus database with same CATH homology
 1QVF T;  3CME U;  3I55 U;  3CCE U;  1KC8 V;  1Q7Y V;  3CC7 U;  3CMA U;  1KD1 V;  1YJW U;  3CCS U;  1VQP U;  1VQL U;  1VQ4 U;  2OTL U;  1YJ9 U;  1VQN U;  1Q86 V;  1M1K V;  3CCQ U;  1M90 V;  3G6E U;  3OW2 T;  1VQ7 U;  3G71 U;  1NJI V;  2OTJ U;  1N8R V;  2QA4 U;  3G4S U;  1QVG T;  3CCR U;  1VQO U;  1K8A V;  1YHQ U;  1VQ5 U;  3I56 U;  3CD6 U;  3CCL U;  3CC2 U;  1W2B T;  3CC4 U;  1YI2 U;  3CCU U;  1YJN U;  3CCM U;  2QEX U;  1VQ9 U;  1VQM U;  1K73 V;  1YIT U;  1VQK U;  1VQ6 U;  3CXC T;  1JJD A;  1K9M V;  3CPW T;  1KQS T;  3CCV U;  3CCJ U;  1YIJ U;  1JJ2 T;  1VQ8 U;  1Q81 V;  1Q82 V;  1S72 U;  5AN9 G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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