3NQ0A

Crystal structure of tyrosinase from bacillus megaterium crystallized in the absence of zinc
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
283
structure length
283
Chain Sequence
KYRVRKNVLHLTDTEKRDFVRTVLILKEKGIYDRYIAWHGAAGKFHTPPGSDRNAAHMSSAFLPWHREYLLRFERDLQSINPEVTLPYWEWETDAQMQDPSQSQIWSADFMGGNGNPIKDFIVDTGPFAAGRWTTIDEQGNPSGGLKRNFGATKEAPTLPTRDDVLNALKITQYDTPPWDMTSQNSFRNQLEGFINGPQLHNRVHRWVGGQMGVVPTAPNDPVFFLHHANVDRIWAVWQIIHRNQNYQPMKNGPFGQNFRDPMYPWNTTPEDVMNHRKLGYVY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title First structures of an active bacterial tyrosinase reveal copper plasticity.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Bacillus megaterium
molecule keywords Tyrosinase
total genus 95
structure length 283
sequence length 283
chains with identical sequence B
ec nomenclature ec 1.14.18.1: Tyrosinase.
pdb deposition date 2010-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 3nq0A00
4L37B 1WX5A 1JS8A 1HC1A 3HHSB 2AHKA 2P3XA 3GWJA 4P6TA 1LL1A 2ZWGA 5I38A 1BUGA 5I3AA 3AWWA 3NQ1A 4OUAA 4D87A 3QJOA 1BT1A 3WKYA 4HD4A 3W6QA 1WX4A 4L37A 4HD6A 3NQ5A 5I3BA 1HCYA 4HD7A 1WX2A 1BT2A 3HHSA 4J3PA 2ZMZA 1OXYA 2Y9WA 3AWSA 2AHLA 3W6WA 2Y9XA 4J6TA 3AWZA 3NTMA 4J3QA 4J3RA 4Z0YA 3NM8A 3WJMB 3NQ0A 1LNLA 1LLAA 2ZMYA 2ZMXA 2ZWFA 3AWXA 3AWVA 4P6SA 1NOLA 1BT3A 5CE9A 4P6RA 3AWTA 4J6UA 2ZWDA 3NPYA 1WXCA 4YZWA 4Z0ZA 4Z10A 4OUAB 3AWYA 3AWUA 2ZWEA 4J6VA 3AX0A 3WJMA
chains in the Genus database with same CATH superfamily
4L37B 1WX5A 1JS8A 1HC1A 3HHSB 2AHKA 2P3XA 3GWJA 4P6TA 1LL1A 2ZWGA 5I38A 1BUGA 5I3AA 3AWWA 3NQ1A 4OUAA 4D87A 3QJOA 1BT1A 3WKYA 4HD4A 3W6QA 1WX4A 4L37A 4HD6A 3NQ5A 5I3BA 1HCYA 4HD7A 1WX2A 1BT2A 3HHSA 4J3PA 2ZMZA 1OXYA 2Y9WA 3AWSA 2AHLA 3W6WA 2Y9XA 4J6TA 3AWZA 3NTMA 4J3QA 4J3RA 4Z0YA 3NM8A 3WJMB 3NQ0A 1LNLA 1LLAA 2ZMYA 2ZMXA 2ZWFA 3AWXA 3AWVA 4P6SA 1NOLA 1BT3A 5CE9A 4P6RA 3AWTA 4J6UA 2ZWDA 3NPYA 1WXCA 4YZWA 4Z0ZA 4Z10A 4OUAB 3AWYA 3AWUA 2ZWEA 4J6VA 3AX0A 3WJMA
chains in the Genus database with same CATH topology
4L37B 1WX5A 1JS8A 1HC1A 3HHSB 2AHKA 2P3XA 3GWJA 4P6TA 1LL1A 2ZWGA 5I38A 1BUGA 5I3AA 3AWWA 3NQ1A 4OUAA 4D87A 3QJOA 1BT1A 3WKYA 4HD4A 3W6QA 1WX4A 4L37A 4HD6A 3NQ5A 5I3BA 1HCYA 4HD7A 1WX2A 1BT2A 3HHSA 4J3PA 2ZMZA 1OXYA 2Y9WA 3AWSA 2AHLA 3W6WA 2Y9XA 4J6TA 3AWZA 3NTMA 4J3QA 4J3RA 4Z0YA 3NM8A 3WJMB 3NQ0A 1LNLA 1LLAA 2ZMYA 2ZMXA 2ZWFA 3AWXA 3AWVA 4P6SA 1NOLA 1BT3A 5CE9A 4P6RA 3AWTA 4J6UA 2ZWDA 3NPYA 1WXCA 4YZWA 4Z0ZA 4Z10A 4OUAB 3AWYA 3AWUA 2ZWEA 4J6VA 3AX0A 3WJMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L37 B;  1WX5 A;  1JS8 A;  1HC1 A;  3HHS B;  2AHK A;  2P3X A;  3GWJ A;  4P6T A;  1LL1 A;  2ZWG A;  5I38 A;  1BUG A;  5I3A A;  3AWW A;  3NQ1 A;  4OUA A;  4D87 A;  3QJO A;  1BT1 A;  3WKY A;  4HD4 A;  3W6Q A;  1WX4 A;  4L37 A;  4HD6 A;  3NQ5 A;  5I3B A;  1HCY A;  4HD7 A;  1WX2 A;  1BT2 A;  3HHS A;  4J3P A;  2ZMZ A;  1OXY A;  2Y9W A;  3AWS A;  2AHL A;  3W6W A;  2Y9X A;  4J6T A;  3AWZ A;  3NTM A;  4J3Q A;  4J3R A;  4Z0Y A;  3NM8 A;  3WJM B;  3NQ0 A;  1LNL A;  1LLA A;  2ZMY A;  2ZMX A;  2ZWF A;  3AWX A;  3AWV A;  4P6S A;  1NOL A;  1BT3 A;  5CE9 A;  4P6R A;  3AWT A;  4J6U A;  2ZWD A;  3NPY A;  1WXC A;  4YZW A;  4Z0Z A;  4Z10 A;  4OUA B;  3AWY A;  3AWU A;  2ZWE A;  4J6V A;  3AX0 A;  3WJM A; 
#chains in the Genus database with same CATH topology
 4L37 B;  1WX5 A;  1JS8 A;  1HC1 A;  3HHS B;  2AHK A;  2P3X A;  3GWJ A;  4P6T A;  1LL1 A;  2ZWG A;  5I38 A;  1BUG A;  5I3A A;  3AWW A;  3NQ1 A;  4OUA A;  4D87 A;  3QJO A;  1BT1 A;  3WKY A;  4HD4 A;  3W6Q A;  1WX4 A;  4L37 A;  4HD6 A;  3NQ5 A;  5I3B A;  1HCY A;  4HD7 A;  1WX2 A;  1BT2 A;  3HHS A;  4J3P A;  2ZMZ A;  1OXY A;  2Y9W A;  3AWS A;  2AHL A;  3W6W A;  2Y9X A;  4J6T A;  3AWZ A;  3NTM A;  4J3Q A;  4J3R A;  4Z0Y A;  3NM8 A;  3WJM B;  3NQ0 A;  1LNL A;  1LLA A;  2ZMY A;  2ZMX A;  2ZWF A;  3AWX A;  3AWV A;  4P6S A;  1NOL A;  1BT3 A;  5CE9 A;  4P6R A;  3AWT A;  4J6U A;  2ZWD A;  3NPY A;  1WXC A;  4YZW A;  4Z0Z A;  4Z10 A;  4OUA B;  3AWY A;  3AWU A;  2ZWE A;  4J6V A;  3AX0 A;  3WJM A; 
#chains in the Genus database with same CATH homology
 4L37 B;  1WX5 A;  1JS8 A;  1HC1 A;  3HHS B;  2AHK A;  2P3X A;  3GWJ A;  4P6T A;  1LL1 A;  2ZWG A;  5I38 A;  1BUG A;  5I3A A;  3AWW A;  3NQ1 A;  4OUA A;  4D87 A;  3QJO A;  1BT1 A;  3WKY A;  4HD4 A;  3W6Q A;  1WX4 A;  4L37 A;  4HD6 A;  3NQ5 A;  5I3B A;  1HCY A;  4HD7 A;  1WX2 A;  1BT2 A;  3HHS A;  4J3P A;  2ZMZ A;  1OXY A;  2Y9W A;  3AWS A;  2AHL A;  3W6W A;  2Y9X A;  4J6T A;  3AWZ A;  3NTM A;  4J3Q A;  4J3R A;  4Z0Y A;  3NM8 A;  3WJM B;  3NQ0 A;  1LNL A;  1LLA A;  2ZMY A;  2ZMX A;  2ZWF A;  3AWX A;  3AWV A;  4P6S A;  1NOL A;  1BT3 A;  5CE9 A;  4P6R A;  3AWT A;  4J6U A;  2ZWD A;  3NPY A;  1WXC A;  4YZW A;  4Z0Z A;  4Z10 A;  4OUA B;  3AWY A;  3AWU A;  2ZWE A;  4J6V A;  3AX0 A;  3WJM A; 
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