3NQ5A

Crystal structure of tyrosinase from bacillus megaterium r209h mutant
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
285
structure length
285
Chain Sequence
KYRVRKNVLHLTDTEKRDFVRTVLILKEKGIYDRYIAWHGAAGKFHTPPGSDRNAAHMSSAFLPWHREYLLRFERDLQSINPEVTLPYWEWETDAQMQDPSQSQIWSADFMGGNGNPIKDFIVDTGPFAAGRWTTIDEQGNPSGGLKRNFGATKEAPTLPTRDDVLNALKITQYDTPPWDMTSQNSFRNQLEGFINGPQLHNRVHHWVGGQMGVVPTAPNDPVFFLHHANVDRIWAVWQIIHRNQNYQPMKNGPFGQNFRDPMYPWNTTPEDVMNHRKLGYVYDI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title First structures of an active bacterial tyrosinase reveal copper plasticity.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Bacillus megaterium
molecule keywords Tyrosinase
total genus 101
structure length 285
sequence length 285
chains with identical sequence B
ec nomenclature ec 1.14.18.1: Tyrosinase.
pdb deposition date 2010-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 3nq5A00
1BT3A 3AWXA 1LNLA 1WXCA 3HHSB 4HD7A 3NQ1A 2AHKA 5I3BA 1WX4A 2ZWFA 4HD4A 1BT2A 2ZWDA 2AHLA 4J3PA 1WX5A 3NQ0A 1BUGA 2Y9XA 4J6VA 5CE9A 1BT1A 1JS8A 4Z0YA 1HC1A 4J3RA 4L37B 4OUAA 2ZWEA 3AWTA 2ZWGA 2P3XA 4J3QA 4P6RA 3AWWA 1NOLA 4P6TA 3GWJA 1OXYA 3AX0A 4YZWA 4J6TA 3AWYA 3WJMA 2ZMXA 3WKYA 4D87A 3AWUA 4P6SA 2Y9WA 1LLAA 3AWSA 4HD6A 3AWZA 3WJMB 5I3AA 2ZMZA 3AWVA 3QJOA 4J6UA 3NM8A 4OUAB 4Z10A 2ZMYA 3NPYA 4Z0ZA 3W6WA 3HHSA 3NQ5A 1WX2A 4L37A 1HCYA 1LL1A 3W6QA 3NTMA 5I38A
chains in the Genus database with same CATH superfamily
1BT3A 3AWXA 1LNLA 1WXCA 3HHSB 4HD7A 3NQ1A 2AHKA 5I3BA 1WX4A 2ZWFA 4HD4A 1BT2A 2ZWDA 2AHLA 4J3PA 1WX5A 3NQ0A 1BUGA 2Y9XA 4J6VA 5CE9A 1BT1A 1JS8A 4Z0YA 1HC1A 4J3RA 4L37B 4OUAA 2ZWEA 3AWTA 2ZWGA 2P3XA 4J3QA 4P6RA 3AWWA 1NOLA 4P6TA 3GWJA 1OXYA 3AX0A 4YZWA 4J6TA 3AWYA 3WJMA 2ZMXA 3WKYA 4D87A 3AWUA 4P6SA 2Y9WA 1LLAA 3AWSA 4HD6A 3AWZA 3WJMB 5I3AA 2ZMZA 3AWVA 3QJOA 4J6UA 3NM8A 4OUAB 4Z10A 2ZMYA 3NPYA 4Z0ZA 3W6WA 3HHSA 3NQ5A 1WX2A 4L37A 1HCYA 1LL1A 3W6QA 3NTMA 5I38A
chains in the Genus database with same CATH topology
1BT3A 3AWXA 1LNLA 1WXCA 3HHSB 4HD7A 3NQ1A 2AHKA 5I3BA 1WX4A 2ZWFA 4HD4A 1BT2A 2ZWDA 2AHLA 4J3PA 1WX5A 3NQ0A 1BUGA 2Y9XA 4J6VA 5CE9A 1BT1A 1JS8A 4Z0YA 1HC1A 4J3RA 4L37B 4OUAA 2ZWEA 3AWTA 2ZWGA 2P3XA 4J3QA 4P6RA 3AWWA 1NOLA 4P6TA 3GWJA 1OXYA 3AX0A 4YZWA 4J6TA 3AWYA 3WJMA 2ZMXA 3WKYA 4D87A 3AWUA 4P6SA 2Y9WA 1LLAA 3AWSA 4HD6A 3AWZA 3WJMB 5I3AA 2ZMZA 3AWVA 3QJOA 4J6UA 3NM8A 4OUAB 4Z10A 2ZMYA 3NPYA 4Z0ZA 3W6WA 3HHSA 3NQ5A 1WX2A 4L37A 1HCYA 1LL1A 3W6QA 3NTMA 5I38A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BT3 A;  3AWX A;  1LNL A;  1WXC A;  3HHS B;  4HD7 A;  3NQ1 A;  2AHK A;  5I3B A;  1WX4 A;  2ZWF A;  4HD4 A;  1BT2 A;  2ZWD A;  2AHL A;  4J3P A;  1WX5 A;  3NQ0 A;  1BUG A;  2Y9X A;  4J6V A;  5CE9 A;  1BT1 A;  1JS8 A;  4Z0Y A;  1HC1 A;  4J3R A;  4L37 B;  4OUA A;  2ZWE A;  3AWT A;  2ZWG A;  2P3X A;  4J3Q A;  4P6R A;  3AWW A;  1NOL A;  4P6T A;  3GWJ A;  1OXY A;  3AX0 A;  4YZW A;  4J6T A;  3AWY A;  3WJM A;  2ZMX A;  3WKY A;  4D87 A;  3AWU A;  4P6S A;  2Y9W A;  1LLA A;  3AWS A;  4HD6 A;  3AWZ A;  3WJM B;  5I3A A;  2ZMZ A;  3AWV A;  3QJO A;  4J6U A;  3NM8 A;  4OUA B;  4Z10 A;  2ZMY A;  3NPY A;  4Z0Z A;  3W6W A;  3HHS A;  3NQ5 A;  1WX2 A;  4L37 A;  1HCY A;  1LL1 A;  3W6Q A;  3NTM A;  5I38 A; 
#chains in the Genus database with same CATH topology
 1BT3 A;  3AWX A;  1LNL A;  1WXC A;  3HHS B;  4HD7 A;  3NQ1 A;  2AHK A;  5I3B A;  1WX4 A;  2ZWF A;  4HD4 A;  1BT2 A;  2ZWD A;  2AHL A;  4J3P A;  1WX5 A;  3NQ0 A;  1BUG A;  2Y9X A;  4J6V A;  5CE9 A;  1BT1 A;  1JS8 A;  4Z0Y A;  1HC1 A;  4J3R A;  4L37 B;  4OUA A;  2ZWE A;  3AWT A;  2ZWG A;  2P3X A;  4J3Q A;  4P6R A;  3AWW A;  1NOL A;  4P6T A;  3GWJ A;  1OXY A;  3AX0 A;  4YZW A;  4J6T A;  3AWY A;  3WJM A;  2ZMX A;  3WKY A;  4D87 A;  3AWU A;  4P6S A;  2Y9W A;  1LLA A;  3AWS A;  4HD6 A;  3AWZ A;  3WJM B;  5I3A A;  2ZMZ A;  3AWV A;  3QJO A;  4J6U A;  3NM8 A;  4OUA B;  4Z10 A;  2ZMY A;  3NPY A;  4Z0Z A;  3W6W A;  3HHS A;  3NQ5 A;  1WX2 A;  4L37 A;  1HCY A;  1LL1 A;  3W6Q A;  3NTM A;  5I38 A; 
#chains in the Genus database with same CATH homology
 1BT3 A;  3AWX A;  1LNL A;  1WXC A;  3HHS B;  4HD7 A;  3NQ1 A;  2AHK A;  5I3B A;  1WX4 A;  2ZWF A;  4HD4 A;  1BT2 A;  2ZWD A;  2AHL A;  4J3P A;  1WX5 A;  3NQ0 A;  1BUG A;  2Y9X A;  4J6V A;  5CE9 A;  1BT1 A;  1JS8 A;  4Z0Y A;  1HC1 A;  4J3R A;  4L37 B;  4OUA A;  2ZWE A;  3AWT A;  2ZWG A;  2P3X A;  4J3Q A;  4P6R A;  3AWW A;  1NOL A;  4P6T A;  3GWJ A;  1OXY A;  3AX0 A;  4YZW A;  4J6T A;  3AWY A;  3WJM A;  2ZMX A;  3WKY A;  4D87 A;  3AWU A;  4P6S A;  2Y9W A;  1LLA A;  3AWS A;  4HD6 A;  3AWZ A;  3WJM B;  5I3A A;  2ZMZ A;  3AWV A;  3QJO A;  4J6U A;  3NM8 A;  4OUA B;  4Z10 A;  2ZMY A;  3NPY A;  4Z0Z A;  3W6W A;  3HHS A;  3NQ5 A;  1WX2 A;  4L37 A;  1HCY A;  1LL1 A;  3W6Q A;  3NTM A;  5I38 A; 
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similar chains in the Genus database (?% sequence similarity)
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