3NQ5A

Crystal structure of tyrosinase from bacillus megaterium r209h mutant
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
285
structure length
285
Chain Sequence
KYRVRKNVLHLTDTEKRDFVRTVLILKEKGIYDRYIAWHGAAGKFHTPPGSDRNAAHMSSAFLPWHREYLLRFERDLQSINPEVTLPYWEWETDAQMQDPSQSQIWSADFMGGNGNPIKDFIVDTGPFAAGRWTTIDEQGNPSGGLKRNFGATKEAPTLPTRDDVLNALKITQYDTPPWDMTSQNSFRNQLEGFINGPQLHNRVHHWVGGQMGVVPTAPNDPVFFLHHANVDRIWAVWQIIHRNQNYQPMKNGPFGQNFRDPMYPWNTTPEDVMNHRKLGYVYDI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title First structures of an active bacterial tyrosinase reveal copper plasticity.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Bacillus megaterium
molecule keywords Tyrosinase
total genus 101
structure length 285
sequence length 285
chains with identical sequence B
ec nomenclature ec 1.14.18.1: Tyrosinase.
pdb deposition date 2010-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 3nq5A00
2Y9WA 3GWJA 4Z0YA 4Z0ZA 3QJOA 3AWWA 5I3BA 5I3AA 1BT3A 5CE9A 3AWTA 4P6TA 2AHKA 1LL1A 3AWVA 4J6VA 2AHLA 2ZMZA 3WJMA 3NM8A 4HD6A 1WX4A 4OUAB 1WX5A 4YZWA 4Z10A 3AWSA 4OUAA 3AWUA 2ZMXA 4J6UA 3WKYA 1BT2A 1LNLA 2ZWFA 3NQ0A 3AWXA 3W6WA 4P6RA 3WJMB 1BUGA 1JS8A 3AX0A 2P3XA 1OXYA 4D87A 3AWZA 1WX2A 1HCYA 3W6QA 3HHSA 4L37B 2Y9XA 2ZWEA 1WXCA 4L37A 1HC1A 2ZWGA 3AWYA 5I38A 1LLAA 2ZWDA 4J3RA 4P6SA 4HD4A 4HD7A 3NQ5A 2ZMYA 3HHSB 4J6TA 3NQ1A 3NPYA 4J3PA 1NOLA 1BT1A 4J3QA 3NTMA
chains in the Genus database with same CATH superfamily
2Y9WA 3GWJA 4Z0YA 4Z0ZA 3QJOA 3AWWA 5I3BA 5I3AA 1BT3A 5CE9A 3AWTA 4P6TA 2AHKA 1LL1A 3AWVA 4J6VA 2AHLA 2ZMZA 3WJMA 3NM8A 4HD6A 1WX4A 4OUAB 1WX5A 4YZWA 4Z10A 3AWSA 4OUAA 3AWUA 2ZMXA 4J6UA 3WKYA 1BT2A 1LNLA 2ZWFA 3NQ0A 3AWXA 3W6WA 4P6RA 3WJMB 1BUGA 1JS8A 3AX0A 2P3XA 1OXYA 4D87A 3AWZA 1WX2A 1HCYA 3W6QA 3HHSA 4L37B 2Y9XA 2ZWEA 1WXCA 4L37A 1HC1A 2ZWGA 3AWYA 5I38A 1LLAA 2ZWDA 4J3RA 4P6SA 4HD4A 4HD7A 3NQ5A 2ZMYA 3HHSB 4J6TA 3NQ1A 3NPYA 4J3PA 1NOLA 1BT1A 4J3QA 3NTMA
chains in the Genus database with same CATH topology
2Y9WA 3GWJA 4Z0YA 4Z0ZA 3QJOA 3AWWA 5I3BA 5I3AA 1BT3A 5CE9A 3AWTA 4P6TA 2AHKA 1LL1A 3AWVA 4J6VA 2AHLA 2ZMZA 3WJMA 3NM8A 4HD6A 1WX4A 4OUAB 1WX5A 4YZWA 4Z10A 3AWSA 4OUAA 3AWUA 2ZMXA 4J6UA 3WKYA 1BT2A 1LNLA 2ZWFA 3NQ0A 3AWXA 3W6WA 4P6RA 3WJMB 1BUGA 1JS8A 3AX0A 2P3XA 1OXYA 4D87A 3AWZA 1WX2A 1HCYA 3W6QA 3HHSA 4L37B 2Y9XA 2ZWEA 1WXCA 4L37A 1HC1A 2ZWGA 3AWYA 5I38A 1LLAA 2ZWDA 4J3RA 4P6SA 4HD4A 4HD7A 3NQ5A 2ZMYA 3HHSB 4J6TA 3NQ1A 3NPYA 4J3PA 1NOLA 1BT1A 4J3QA 3NTMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y9W A;  3GWJ A;  4Z0Y A;  4Z0Z A;  3QJO A;  3AWW A;  5I3B A;  5I3A A;  1BT3 A;  5CE9 A;  3AWT A;  4P6T A;  2AHK A;  1LL1 A;  3AWV A;  4J6V A;  2AHL A;  2ZMZ A;  3WJM A;  3NM8 A;  4HD6 A;  1WX4 A;  4OUA B;  1WX5 A;  4YZW A;  4Z10 A;  3AWS A;  4OUA A;  3AWU A;  2ZMX A;  4J6U A;  3WKY A;  1BT2 A;  1LNL A;  2ZWF A;  3NQ0 A;  3AWX A;  3W6W A;  4P6R A;  3WJM B;  1BUG A;  1JS8 A;  3AX0 A;  2P3X A;  1OXY A;  4D87 A;  3AWZ A;  1WX2 A;  1HCY A;  3W6Q A;  3HHS A;  4L37 B;  2Y9X A;  2ZWE A;  1WXC A;  4L37 A;  1HC1 A;  2ZWG A;  3AWY A;  5I38 A;  1LLA A;  2ZWD A;  4J3R A;  4P6S A;  4HD4 A;  4HD7 A;  3NQ5 A;  2ZMY A;  3HHS B;  4J6T A;  3NQ1 A;  3NPY A;  4J3P A;  1NOL A;  1BT1 A;  4J3Q A;  3NTM A; 
#chains in the Genus database with same CATH topology
 2Y9W A;  3GWJ A;  4Z0Y A;  4Z0Z A;  3QJO A;  3AWW A;  5I3B A;  5I3A A;  1BT3 A;  5CE9 A;  3AWT A;  4P6T A;  2AHK A;  1LL1 A;  3AWV A;  4J6V A;  2AHL A;  2ZMZ A;  3WJM A;  3NM8 A;  4HD6 A;  1WX4 A;  4OUA B;  1WX5 A;  4YZW A;  4Z10 A;  3AWS A;  4OUA A;  3AWU A;  2ZMX A;  4J6U A;  3WKY A;  1BT2 A;  1LNL A;  2ZWF A;  3NQ0 A;  3AWX A;  3W6W A;  4P6R A;  3WJM B;  1BUG A;  1JS8 A;  3AX0 A;  2P3X A;  1OXY A;  4D87 A;  3AWZ A;  1WX2 A;  1HCY A;  3W6Q A;  3HHS A;  4L37 B;  2Y9X A;  2ZWE A;  1WXC A;  4L37 A;  1HC1 A;  2ZWG A;  3AWY A;  5I38 A;  1LLA A;  2ZWD A;  4J3R A;  4P6S A;  4HD4 A;  4HD7 A;  3NQ5 A;  2ZMY A;  3HHS B;  4J6T A;  3NQ1 A;  3NPY A;  4J3P A;  1NOL A;  1BT1 A;  4J3Q A;  3NTM A; 
#chains in the Genus database with same CATH homology
 2Y9W A;  3GWJ A;  4Z0Y A;  4Z0Z A;  3QJO A;  3AWW A;  5I3B A;  5I3A A;  1BT3 A;  5CE9 A;  3AWT A;  4P6T A;  2AHK A;  1LL1 A;  3AWV A;  4J6V A;  2AHL A;  2ZMZ A;  3WJM A;  3NM8 A;  4HD6 A;  1WX4 A;  4OUA B;  1WX5 A;  4YZW A;  4Z10 A;  3AWS A;  4OUA A;  3AWU A;  2ZMX A;  4J6U A;  3WKY A;  1BT2 A;  1LNL A;  2ZWF A;  3NQ0 A;  3AWX A;  3W6W A;  4P6R A;  3WJM B;  1BUG A;  1JS8 A;  3AX0 A;  2P3X A;  1OXY A;  4D87 A;  3AWZ A;  1WX2 A;  1HCY A;  3W6Q A;  3HHS A;  4L37 B;  2Y9X A;  2ZWE A;  1WXC A;  4L37 A;  1HC1 A;  2ZWG A;  3AWY A;  5I38 A;  1LLA A;  2ZWD A;  4J3R A;  4P6S A;  4HD4 A;  4HD7 A;  3NQ5 A;  2ZMY A;  3HHS B;  4J6T A;  3NQ1 A;  3NPY A;  4J3P A;  1NOL A;  1BT1 A;  4J3Q A;  3NTM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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