3NTMA

Crystal structure of tyrosinase from bacillus megaterium crystallized in the absence of zinc, partial occupancy of cub
Total Genus 94
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
283
structure length
279
Chain Sequence
RVRKNVLHLTDTEKRDFVRTVLILKEKGIYDRYIAWHGAAGKFHTPPGSDRNAAHMSSAFLPWHREYLLRFERDLQSINPEVTLPYWEWETDAPSQSQIWSADFMGGNGNPIKDFIVDTGPFAAGRWTTIDEQGNPSGGLKRNFGATKEAPTLPTRDDVLNALKITQYDTPPWDMTSQNSFRNQLEGFINGPQLHNRVHRWVGGQMGVVPTAPNDPVFFLHHANVDRIWAVWQIIHRNQNYQPMKNGPFGQNFRDPMYPWNTTPEDVMNHRKLGYVYDI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title First structures of an active bacterial tyrosinase reveal copper plasticity
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Bacillus megaterium
molecule keywords Tyrosinase
total genus 94
structure length 279
sequence length 283
chains with identical sequence B
ec nomenclature ec 1.14.18.1: Tyrosinase.
pdb deposition date 2010-07-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 3ntmA00
4L37B 3WKYA 3HHSA 2Y9XA 3NM8A 4Z0ZA 1HC1A 1LLAA 3WJMA 3AWWA 4HD4A 4Z10A 2ZWEA 3NPYA 1HCYA 2P3XA 1JS8A 1BUGA 4J6TA 2ZMYA 3AWTA 2ZMXA 3AWVA 3NTMA 3AWZA 4J3QA 3NQ0A 4D87A 1WXCA 4HD6A 3AWXA 2Y9WA 4Z0YA 1BT3A 1WX5A 3AWUA 3NQ1A 4OUAB 4J3RA 2AHKA 1LNLA 1WX2A 4J3PA 1BT1A 4HD7A 4YZWA 5I3AA 4P6TA 3HHSB 1BT2A 3NQ5A 4L37A 3QJOA 1WX4A 3W6WA 3WJMB 3AWYA 5CE9A 3AX0A 2ZWFA 5I38A 4J6VA 2ZWDA 4J6UA 1LL1A 4OUAA 2ZWGA 2ZMZA 1OXYA 4P6SA 1NOLA 5I3BA 3AWSA 4P6RA 3W6QA 3GWJA 2AHLA
chains in the Genus database with same CATH superfamily
4L37B 3WKYA 3HHSA 2Y9XA 3NM8A 4Z0ZA 1HC1A 1LLAA 3WJMA 3AWWA 4HD4A 4Z10A 2ZWEA 3NPYA 1HCYA 2P3XA 1JS8A 1BUGA 4J6TA 2ZMYA 3AWTA 2ZMXA 3AWVA 3NTMA 3AWZA 4J3QA 3NQ0A 4D87A 1WXCA 4HD6A 3AWXA 2Y9WA 4Z0YA 1BT3A 1WX5A 3AWUA 3NQ1A 4OUAB 4J3RA 2AHKA 1LNLA 1WX2A 4J3PA 1BT1A 4HD7A 4YZWA 5I3AA 4P6TA 3HHSB 1BT2A 3NQ5A 4L37A 3QJOA 1WX4A 3W6WA 3WJMB 3AWYA 5CE9A 3AX0A 2ZWFA 5I38A 4J6VA 2ZWDA 4J6UA 1LL1A 4OUAA 2ZWGA 2ZMZA 1OXYA 4P6SA 1NOLA 5I3BA 3AWSA 4P6RA 3W6QA 3GWJA 2AHLA
chains in the Genus database with same CATH topology
4L37B 3WKYA 3HHSA 2Y9XA 3NM8A 4Z0ZA 1HC1A 1LLAA 3WJMA 3AWWA 4HD4A 4Z10A 2ZWEA 3NPYA 1HCYA 2P3XA 1JS8A 1BUGA 4J6TA 2ZMYA 3AWTA 2ZMXA 3AWVA 3NTMA 3AWZA 4J3QA 3NQ0A 4D87A 1WXCA 4HD6A 3AWXA 2Y9WA 4Z0YA 1BT3A 1WX5A 3AWUA 3NQ1A 4OUAB 4J3RA 2AHKA 1LNLA 1WX2A 4J3PA 1BT1A 4HD7A 4YZWA 5I3AA 4P6TA 3HHSB 1BT2A 3NQ5A 4L37A 3QJOA 1WX4A 3W6WA 3WJMB 3AWYA 5CE9A 3AX0A 2ZWFA 5I38A 4J6VA 2ZWDA 4J6UA 1LL1A 4OUAA 2ZWGA 2ZMZA 1OXYA 4P6SA 1NOLA 5I3BA 3AWSA 4P6RA 3W6QA 3GWJA 2AHLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L37 B;  3WKY A;  3HHS A;  2Y9X A;  3NM8 A;  4Z0Z A;  1HC1 A;  1LLA A;  3WJM A;  3AWW A;  4HD4 A;  4Z10 A;  2ZWE A;  3NPY A;  1HCY A;  2P3X A;  1JS8 A;  1BUG A;  4J6T A;  2ZMY A;  3AWT A;  2ZMX A;  3AWV A;  3NTM A;  3AWZ A;  4J3Q A;  3NQ0 A;  4D87 A;  1WXC A;  4HD6 A;  3AWX A;  2Y9W A;  4Z0Y A;  1BT3 A;  1WX5 A;  3AWU A;  3NQ1 A;  4OUA B;  4J3R A;  2AHK A;  1LNL A;  1WX2 A;  4J3P A;  1BT1 A;  4HD7 A;  4YZW A;  5I3A A;  4P6T A;  3HHS B;  1BT2 A;  3NQ5 A;  4L37 A;  3QJO A;  1WX4 A;  3W6W A;  3WJM B;  3AWY A;  5CE9 A;  3AX0 A;  2ZWF A;  5I38 A;  4J6V A;  2ZWD A;  4J6U A;  1LL1 A;  4OUA A;  2ZWG A;  2ZMZ A;  1OXY A;  4P6S A;  1NOL A;  5I3B A;  3AWS A;  4P6R A;  3W6Q A;  3GWJ A;  2AHL A; 
#chains in the Genus database with same CATH topology
 4L37 B;  3WKY A;  3HHS A;  2Y9X A;  3NM8 A;  4Z0Z A;  1HC1 A;  1LLA A;  3WJM A;  3AWW A;  4HD4 A;  4Z10 A;  2ZWE A;  3NPY A;  1HCY A;  2P3X A;  1JS8 A;  1BUG A;  4J6T A;  2ZMY A;  3AWT A;  2ZMX A;  3AWV A;  3NTM A;  3AWZ A;  4J3Q A;  3NQ0 A;  4D87 A;  1WXC A;  4HD6 A;  3AWX A;  2Y9W A;  4Z0Y A;  1BT3 A;  1WX5 A;  3AWU A;  3NQ1 A;  4OUA B;  4J3R A;  2AHK A;  1LNL A;  1WX2 A;  4J3P A;  1BT1 A;  4HD7 A;  4YZW A;  5I3A A;  4P6T A;  3HHS B;  1BT2 A;  3NQ5 A;  4L37 A;  3QJO A;  1WX4 A;  3W6W A;  3WJM B;  3AWY A;  5CE9 A;  3AX0 A;  2ZWF A;  5I38 A;  4J6V A;  2ZWD A;  4J6U A;  1LL1 A;  4OUA A;  2ZWG A;  2ZMZ A;  1OXY A;  4P6S A;  1NOL A;  5I3B A;  3AWS A;  4P6R A;  3W6Q A;  3GWJ A;  2AHL A; 
#chains in the Genus database with same CATH homology
 4L37 B;  3WKY A;  3HHS A;  2Y9X A;  3NM8 A;  4Z0Z A;  1HC1 A;  1LLA A;  3WJM A;  3AWW A;  4HD4 A;  4Z10 A;  2ZWE A;  3NPY A;  1HCY A;  2P3X A;  1JS8 A;  1BUG A;  4J6T A;  2ZMY A;  3AWT A;  2ZMX A;  3AWV A;  3NTM A;  3AWZ A;  4J3Q A;  3NQ0 A;  4D87 A;  1WXC A;  4HD6 A;  3AWX A;  2Y9W A;  4Z0Y A;  1BT3 A;  1WX5 A;  3AWU A;  3NQ1 A;  4OUA B;  4J3R A;  2AHK A;  1LNL A;  1WX2 A;  4J3P A;  1BT1 A;  4HD7 A;  4YZW A;  5I3A A;  4P6T A;  3HHS B;  1BT2 A;  3NQ5 A;  4L37 A;  3QJO A;  1WX4 A;  3W6W A;  3WJM B;  3AWY A;  5CE9 A;  3AX0 A;  2ZWF A;  5I38 A;  4J6V A;  2ZWD A;  4J6U A;  1LL1 A;  4OUA A;  2ZWG A;  2ZMZ A;  1OXY A;  4P6S A;  1NOL A;  5I3B A;  3AWS A;  4P6R A;  3W6Q A;  3GWJ A;  2AHL A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...