3P16A

Crystal structure of dna polymerase iii sliding clamp
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
389
structure length
375
Chain Sequence
DLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDAVSTDYVYLLMPVRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of DNA polymerase III beta sliding clamp from Mycobacterium tuberculosis.
pubmed doi rcsb
molecule tags Transferase
source organism Mycobacterium tuberculosis
molecule keywords DNA polymerase III subunit beta
total genus 70
structure length 375
sequence length 389
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2010-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3p16A01
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3p16A02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3p16A03
2AVTA 4K3MA 1JQLA 4K3RA 4K3KA 4N99A 4TRTA 2AWAA 3Q4LA 4K3LA 3L10A 3L0WA 3L0XA 3QSBB 4PNUA 3BEPA 4S3IA 1UNNA 4K3SA 4OVGA 4N9AA 4OVHA 4TSZA 4N94A 3T0PA 4N95A 4K74A 4PNVA 1VPKA 4TR7A 4TR6A 2XURA 5AH2A 4MJRA 4MJQA 4N98A 3QSBA 5AH4A 4K3QA 4K3PA 1OK7A 3Q4JA 5FVEA 3P16A 3D1GA 4N96A 5AGVA 1JQJA 5AGUA 4PNWA 3D1FA 4N97A 5FRQA 3D1EA 3PGEB 3RB9A 2POLA 3PWEA 3Q4KA 4RKIA 4K3OA 4MJPA 4TR8A 4OVFA 3F1VA 1MMIA
chains in the Genus database with same CATH superfamily
2AVTA 4K3MA 1JQLA 4K3RA 4K3KA 4N99A 4TRTA 2AWAA 3Q4LA 4K3LA 3PGEA 3L10A 3L0WA 3L0XA 3QSBB 4PNUA 3BEPA 4S3IA 1UNNA 4K3SA 4OVGA 4N9AA 4OVHA 4TSZA 4N94A 3T0PA 4N95A 4K74A 4PNVA 1VPKA 4TR7A 4TR6A 2XURA 5AH2A 4MJRA 4MJQA 4N98A 3QSBA 5AH4A 4K3QA 4K3PA 1OK7A 3Q4JA 5FVEA 3P16A 3D1GA 4N96A 5AGVA 1JQJA 5AGUA 4PNWA 3L10B 3D1FA 3L0WB 3L0XB 4N97A 3D1EA 3PGEB 5FRQA 3RB9A 2POLA 3PWEA 3Q4KA 4RKIA 4K3OA 4MJPA 4TR8A 4OVFA 3F1VA 1MMIA
chains in the Genus database with same CATH topology
2AVTA 4K3MA 1JQLA 4K3RA 4K3KA 4N99A 4TRTA 2AWAA 3Q4LA 4K3LA 3L10A 3L0WA 3L0XA 3QSBB 4PNUA 3BEPA 4S3IA 1UNNA 4K3SA 4OVGA 4N9AA 4OVHA 4TSZA 4N94A 3T0PA 4N95A 4K74A 4PNVA 1VPKA 4TR7A 4TR6A 2XURA 5AH2A 4MJRA 4MJQA 4N98A 3QSBA 5AH4A 4K3QA 4K3PA 1OK7A 3Q4JA 5FVEA 3P16A 3D1GA 4N96A 5AGVA 1JQJA 5AGUA 4PNWA 3D1FA 4N97A 5FRQA 3D1EA 3PGEB 3RB9A 2POLA 3PWEA 3Q4KA 4RKIA 4K3OA 4MJPA 4TR8A 4OVFA 3F1VA 1MMIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AVT A;  4K3M A;  1JQL A;  4K3R A;  4K3K A;  4N99 A;  4TRT A;  2AWA A;  3Q4L A;  4K3L A;  3L10 A;  3L0W A;  3L0X A;  3QSB B;  4PNU A;  3BEP A;  4S3I A;  1UNN A;  4K3S A;  4OVG A;  4N9A A;  4OVH A;  4TSZ A;  4N94 A;  3T0P A;  4N95 A;  4K74 A;  4PNV A;  1VPK A;  4TR7 A;  4TR6 A;  2XUR A;  5AH2 A;  4MJR A;  4MJQ A;  4N98 A;  3QSB A;  5AH4 A;  4K3Q A;  4K3P A;  1OK7 A;  3Q4J A;  5FVE A;  3P16 A;  3D1G A;  4N96 A;  5AGV A;  1JQJ A;  5AGU A;  4PNW A;  3D1F A;  4N97 A;  5FRQ A;  3D1E A;  3PGE B;  3RB9 A;  2POL A;  3PWE A;  3Q4K A;  4RKI A;  4K3O A;  4MJP A;  4TR8 A;  4OVF A;  3F1V A;  1MMI A; 
#chains in the Genus database with same CATH topology
 2AVT A;  4K3M A;  1JQL A;  4K3R A;  4K3K A;  4N99 A;  4TRT A;  2AWA A;  3Q4L A;  4K3L A;  3PGE A;  3L10 A;  3L0W A;  3L0X A;  3QSB B;  4PNU A;  3BEP A;  4S3I A;  1UNN A;  4K3S A;  4OVG A;  4N9A A;  4OVH A;  4TSZ A;  4N94 A;  3T0P A;  4N95 A;  4K74 A;  4PNV A;  1VPK A;  4TR7 A;  4TR6 A;  2XUR A;  5AH2 A;  4MJR A;  4MJQ A;  4N98 A;  3QSB A;  5AH4 A;  4K3Q A;  4K3P A;  1OK7 A;  3Q4J A;  5FVE A;  3P16 A;  3D1G A;  4N96 A;  5AGV A;  1JQJ A;  5AGU A;  4PNW A;  3L10 B;  3D1F A;  3L0W B;  3L0X B;  4N97 A;  3D1E A;  3PGE B;  5FRQ A;  3RB9 A;  2POL A;  3PWE A;  3Q4K A;  4RKI A;  4K3O A;  4MJP A;  4TR8 A;  4OVF A;  3F1V A;  1MMI A; 
#chains in the Genus database with same CATH homology
 2AVT A;  4K3M A;  1JQL A;  4K3R A;  4K3K A;  4N99 A;  4TRT A;  2AWA A;  3Q4L A;  4K3L A;  3L10 A;  3L0W A;  3L0X A;  3QSB B;  4PNU A;  3BEP A;  4S3I A;  1UNN A;  4K3S A;  4OVG A;  4N9A A;  4OVH A;  4TSZ A;  4N94 A;  3T0P A;  4N95 A;  4K74 A;  4PNV A;  1VPK A;  4TR7 A;  4TR6 A;  2XUR A;  5AH2 A;  4MJR A;  4MJQ A;  4N98 A;  3QSB A;  5AH4 A;  4K3Q A;  4K3P A;  1OK7 A;  3Q4J A;  5FVE A;  3P16 A;  3D1G A;  4N96 A;  5AGV A;  1JQJ A;  5AGU A;  4PNW A;  3D1F A;  4N97 A;  5FRQ A;  3D1E A;  3PGE B;  3RB9 A;  2POL A;  3PWE A;  3Q4K A;  4RKI A;  4K3O A;  4MJP A;  4TR8 A;  4OVF A;  3F1V A;  1MMI A; 
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similar chains in the Genus database (?% sequence similarity)
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