3PWEA

Crystal structure of the e. coli beta clamp mutant r103c, i305c, c260s, c333s at 2.2a resolution
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
366
structure length
366
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGCSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGSDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEECLDVTYSGAEMEIGFNVSYVLDVLNALKSENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The E. coli clamp loader can actively pry open the beta-sliding clamp
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords DNA polymerase III subunit beta
total genus 84
structure length 366
sequence length 366
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2010-12-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3pweA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3pweA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3pweA01
3Q4JA 4N98A 3RB9A 4TR8A 3T0PA 3QSBA 3L0WA 3QSBB 5FRQA 4MJQA 2AVTA 4S3IA 4PNVA 4TRTA 2XURA 4K3QA 4K3OA 4N96A 1UNNA 1JQJA 4TR7A 2AWAA 4N9AA 3Q4KA 5AH4A 3D1EA 4K3MA 3BEPA 4OVGA 2POLA 4TR6A 3F1VA 4PNWA 3D1GA 4N99A 4PNUA 1VPKA 4MJPA 5AGVA 5AH2A 4K3RA 3PGEB 3P16A 4K3KA 1OK7A 4N94A 4K3SA 3L10A 4K74A 1MMIA 4MJRA 4K3LA 3D1FA 3L0XA 4N97A 4N95A 5FVEA 1JQLA 4TSZA 3PWEA 4OVHA 3Q4LA 4RKIA 4OVFA 5AGUA 4K3PA
chains in the Genus database with same CATH superfamily
3Q4JA 4N98A 3RB9A 4TR8A 3T0PA 3QSBA 3L0WA 3QSBB 5FRQA 4MJQA 2AVTA 4S3IA 3L0WB 4PNVA 4TRTA 2XURA 4K3QA 4K3OA 4N96A 1UNNA 1JQJA 4TR7A 2AWAA 4N9AA 3Q4KA 5AH4A 3D1EA 4K3MA 3BEPA 4OVGA 2POLA 4TR6A 3F1VA 4PNWA 3D1GA 4N99A 4PNUA 1VPKA 4MJPA 5AGVA 3PGEA 5AH2A 4K3RA 3PGEB 3P16A 4K3KA 1OK7A 4N94A 4K3SA 3L10A 4K74A 1MMIA 3L10B 4K3LA 3D1FA 3L0XA 4MJRA 4N97A 4N95A 5FVEA 1JQLA 4TSZA 3L0XB 3PWEA 4OVHA 3Q4LA 4RKIA 4OVFA 5AGUA 4K3PA
chains in the Genus database with same CATH topology
3Q4JA 4N98A 3RB9A 4TR8A 3T0PA 3QSBA 3L0WA 3QSBB 5FRQA 4MJQA 2AVTA 4S3IA 4PNVA 4TRTA 2XURA 4K3QA 4K3OA 4N96A 1UNNA 1JQJA 4TR7A 2AWAA 4N9AA 3Q4KA 5AH4A 3D1EA 4K3MA 3BEPA 4OVGA 2POLA 4TR6A 3F1VA 4PNWA 3D1GA 4N99A 4PNUA 1VPKA 4MJPA 5AGVA 5AH2A 4K3RA 3PGEB 3P16A 4K3KA 1OK7A 4N94A 4K3SA 3L10A 4K74A 1MMIA 4MJRA 4K3LA 3D1FA 3L0XA 4N97A 4N95A 5FVEA 1JQLA 4TSZA 3PWEA 4OVHA 3Q4LA 4RKIA 4OVFA 5AGUA 4K3PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q4J A;  4N98 A;  3RB9 A;  4TR8 A;  3T0P A;  3QSB A;  3L0W A;  3QSB B;  5FRQ A;  4MJQ A;  2AVT A;  4S3I A;  4PNV A;  4TRT A;  2XUR A;  4K3Q A;  4K3O A;  4N96 A;  1UNN A;  1JQJ A;  4TR7 A;  2AWA A;  4N9A A;  3Q4K A;  5AH4 A;  3D1E A;  4K3M A;  3BEP A;  4OVG A;  2POL A;  4TR6 A;  3F1V A;  4PNW A;  3D1G A;  4N99 A;  4PNU A;  1VPK A;  4MJP A;  5AGV A;  5AH2 A;  4K3R A;  3PGE B;  3P16 A;  4K3K A;  1OK7 A;  4N94 A;  4K3S A;  3L10 A;  4K74 A;  1MMI A;  4MJR A;  4K3L A;  3D1F A;  3L0X A;  4N97 A;  4N95 A;  5FVE A;  1JQL A;  4TSZ A;  3PWE A;  4OVH A;  3Q4L A;  4RKI A;  4OVF A;  5AGU A;  4K3P A; 
#chains in the Genus database with same CATH topology
 3Q4J A;  4N98 A;  3RB9 A;  4TR8 A;  3T0P A;  3QSB A;  3L0W A;  3QSB B;  5FRQ A;  4MJQ A;  2AVT A;  4S3I A;  3L0W B;  4PNV A;  4TRT A;  2XUR A;  4K3Q A;  4K3O A;  4N96 A;  1UNN A;  1JQJ A;  4TR7 A;  2AWA A;  4N9A A;  3Q4K A;  5AH4 A;  3D1E A;  4K3M A;  3BEP A;  4OVG A;  2POL A;  4TR6 A;  3F1V A;  4PNW A;  3D1G A;  4N99 A;  4PNU A;  1VPK A;  4MJP A;  5AGV A;  3PGE A;  5AH2 A;  4K3R A;  3PGE B;  3P16 A;  4K3K A;  1OK7 A;  4N94 A;  4K3S A;  3L10 A;  4K74 A;  1MMI A;  3L10 B;  4K3L A;  3D1F A;  3L0X A;  4MJR A;  4N97 A;  4N95 A;  5FVE A;  1JQL A;  4TSZ A;  3L0X B;  3PWE A;  4OVH A;  3Q4L A;  4RKI A;  4OVF A;  5AGU A;  4K3P A; 
#chains in the Genus database with same CATH homology
 3Q4J A;  4N98 A;  3RB9 A;  4TR8 A;  3T0P A;  3QSB A;  3L0W A;  3QSB B;  5FRQ A;  4MJQ A;  2AVT A;  4S3I A;  4PNV A;  4TRT A;  2XUR A;  4K3Q A;  4K3O A;  4N96 A;  1UNN A;  1JQJ A;  4TR7 A;  2AWA A;  4N9A A;  3Q4K A;  5AH4 A;  3D1E A;  4K3M A;  3BEP A;  4OVG A;  2POL A;  4TR6 A;  3F1V A;  4PNW A;  3D1G A;  4N99 A;  4PNU A;  1VPK A;  4MJP A;  5AGV A;  5AH2 A;  4K3R A;  3PGE B;  3P16 A;  4K3K A;  1OK7 A;  4N94 A;  4K3S A;  3L10 A;  4K74 A;  1MMI A;  4MJR A;  4K3L A;  3D1F A;  3L0X A;  4N97 A;  4N95 A;  5FVE A;  1JQL A;  4TSZ A;  3PWE A;  4OVH A;  3Q4L A;  4RKI A;  4OVF A;  5AGU A;  4K3P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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