3PWEA

Crystal structure of the e. coli beta clamp mutant r103c, i305c, c260s, c333s at 2.2a resolution
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
366
structure length
366
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGCSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGSDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEECLDVTYSGAEMEIGFNVSYVLDVLNALKSENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Escherichia coli
publication title The E. coli clamp loader can actively pry open the beta-sliding clamp
pubmed doi rcsb
molecule keywords DNA polymerase III subunit beta
total genus 84
structure length 366
sequence length 366
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2010-12-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3pweA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3pweA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3pweA01
2XURA 3Q4LA 5FVEA 1OK7A 3L10A 4TR6A 2AVTA 1JQLA 3L0XA 2POLA 3PWEA 5AH4A 3T0PA 3RB9A 3QSBB 4N9AA 4N99A 4K3MA 4TRTA 1MMIA 4S3IA 3D1FA 4OVHA 3F1VA 4TR8A 3BEPA 1VPKA 4K3PA 4N94A 4PNWA 3Q4JA 1JQJA 4K3KA 4N95A 4N96A 5AGVA 3P16A 4K3QA 2AWAA 4OVGA 4MJQA 4K74A 4N98A 4RKIA 5AGUA 1UNNA 4K3LA 4N97A 4PNVA 4K3OA 4PNUA 3PGEB 3D1GA 4MJRA 4MJPA 3Q4KA 4OVFA 5FRQA 3QSBA 4K3RA 5AH2A 4TSZA 3L0WA 4TR7A 3D1EA 4K3SA
chains in the Genus database with same CATH superfamily
2XURA 3Q4LA 5FVEA 1OK7A 3L10A 4TR6A 2AVTA 1JQLA 3L0XA 2POLA 3PWEA 5AH4A 3T0PA 3RB9A 3QSBB 4N9AA 3L0WB 4N99A 4K3MA 4TRTA 1MMIA 4S3IA 3L10B 3D1FA 4OVHA 3F1VA 4TR8A 3L0XB 1VPKA 4K3PA 4N94A 4PNWA 3BEPA 3Q4JA 1JQJA 4K3KA 3PGEA 4N95A 4N96A 5AGVA 3P16A 4K3QA 2AWAA 4OVGA 4MJQA 4K74A 4N98A 4RKIA 5AGUA 1UNNA 4K3LA 4N97A 4PNVA 4K3OA 4PNUA 3PGEB 3D1GA 4MJRA 4MJPA 3Q4KA 4OVFA 5FRQA 3QSBA 4K3RA 5AH2A 4TSZA 3L0WA 4TR7A 3D1EA 4K3SA
chains in the Genus database with same CATH topology
2XURA 3Q4LA 5FVEA 1OK7A 3L10A 4TR6A 2AVTA 1JQLA 3L0XA 2POLA 3PWEA 5AH4A 3T0PA 3RB9A 3QSBB 4N9AA 4N99A 4K3MA 4TRTA 1MMIA 4S3IA 3D1FA 4OVHA 3F1VA 4TR8A 3BEPA 1VPKA 4K3PA 4N94A 4PNWA 3Q4JA 1JQJA 4K3KA 4N95A 4N96A 5AGVA 3P16A 4K3QA 2AWAA 4OVGA 4MJQA 4K74A 4N98A 4RKIA 5AGUA 1UNNA 4K3LA 4N97A 4PNVA 4K3OA 4PNUA 3PGEB 3D1GA 4MJRA 4MJPA 3Q4KA 4OVFA 5FRQA 3QSBA 4K3RA 5AH2A 4TSZA 3L0WA 4TR7A 3D1EA 4K3SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XUR A;  3Q4L A;  5FVE A;  1OK7 A;  3L10 A;  4TR6 A;  2AVT A;  1JQL A;  3L0X A;  2POL A;  3PWE A;  5AH4 A;  3T0P A;  3RB9 A;  3QSB B;  4N9A A;  4N99 A;  4K3M A;  4TRT A;  1MMI A;  4S3I A;  3D1F A;  4OVH A;  3F1V A;  4TR8 A;  3BEP A;  1VPK A;  4K3P A;  4N94 A;  4PNW A;  3Q4J A;  1JQJ A;  4K3K A;  4N95 A;  4N96 A;  5AGV A;  3P16 A;  4K3Q A;  2AWA A;  4OVG A;  4MJQ A;  4K74 A;  4N98 A;  4RKI A;  5AGU A;  1UNN A;  4K3L A;  4N97 A;  4PNV A;  4K3O A;  4PNU A;  3PGE B;  3D1G A;  4MJR A;  4MJP A;  3Q4K A;  4OVF A;  5FRQ A;  3QSB A;  4K3R A;  5AH2 A;  4TSZ A;  3L0W A;  4TR7 A;  3D1E A;  4K3S A; 
#chains in the Genus database with same CATH topology
 2XUR A;  3Q4L A;  5FVE A;  1OK7 A;  3L10 A;  4TR6 A;  2AVT A;  1JQL A;  3L0X A;  2POL A;  3PWE A;  5AH4 A;  3T0P A;  3RB9 A;  3QSB B;  4N9A A;  3L0W B;  4N99 A;  4K3M A;  4TRT A;  1MMI A;  4S3I A;  3L10 B;  3D1F A;  4OVH A;  3F1V A;  4TR8 A;  3L0X B;  1VPK A;  4K3P A;  4N94 A;  4PNW A;  3BEP A;  3Q4J A;  1JQJ A;  4K3K A;  3PGE A;  4N95 A;  4N96 A;  5AGV A;  3P16 A;  4K3Q A;  2AWA A;  4OVG A;  4MJQ A;  4K74 A;  4N98 A;  4RKI A;  5AGU A;  1UNN A;  4K3L A;  4N97 A;  4PNV A;  4K3O A;  4PNU A;  3PGE B;  3D1G A;  4MJR A;  4MJP A;  3Q4K A;  4OVF A;  5FRQ A;  3QSB A;  4K3R A;  5AH2 A;  4TSZ A;  3L0W A;  4TR7 A;  3D1E A;  4K3S A; 
#chains in the Genus database with same CATH homology
 2XUR A;  3Q4L A;  5FVE A;  1OK7 A;  3L10 A;  4TR6 A;  2AVT A;  1JQL A;  3L0X A;  2POL A;  3PWE A;  5AH4 A;  3T0P A;  3RB9 A;  3QSB B;  4N9A A;  4N99 A;  4K3M A;  4TRT A;  1MMI A;  4S3I A;  3D1F A;  4OVH A;  3F1V A;  4TR8 A;  3BEP A;  1VPK A;  4K3P A;  4N94 A;  4PNW A;  3Q4J A;  1JQJ A;  4K3K A;  4N95 A;  4N96 A;  5AGV A;  3P16 A;  4K3Q A;  2AWA A;  4OVG A;  4MJQ A;  4K74 A;  4N98 A;  4RKI A;  5AGU A;  1UNN A;  4K3L A;  4N97 A;  4PNV A;  4K3O A;  4PNU A;  3PGE B;  3D1G A;  4MJR A;  4MJP A;  3Q4K A;  4OVF A;  5FRQ A;  3QSB A;  4K3R A;  5AH2 A;  4TSZ A;  3L0W A;  4TR7 A;  3D1E A;  4K3S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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