3Q4L | Genus

Total Genus 85

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	85
sequence length	368
structure length	364
Chain Sequence	AAMKFTVEREHLLKPLQQVSGPPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 364 atoms

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364 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase/transferase inhibitor
source organism	Escherichia coli
publication title	Structure-based design of short peptide ligands binding onto the E. coli processivity ring. pubmed doi rcsb
molecule keywords	DNA polymerase III subunit beta
total genus	85
structure length	364
sequence length	368
chains with identical sequence	B
ec nomenclature	ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date	2010-12-23

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00712	DNA_pol3_beta	DNA polymerase III beta subunit, N-terminal domain
A	PF02767	DNA_pol3_beta_2	DNA polymerase III beta subunit, central domain
A	PF02768	DNA_pol3_beta_3	DNA polymerase III beta subunit, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	3q4lA02
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	3q4lA03
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	3q4lA01

3L0XA 4N95A 3L10A 4MJPA 2AWAA 4K3PA 4K74A 4TSZA 4N97A 4K3KA 1JQJA 4RKIA 2POLA 1VPKA 4TRTA 5AH2A 3D1GA 5AGUA 4OVHA 1JQLA 3QSBB 4TR6A 3T0PA 4K3QA 5AH4A 2AVTA 4K3LA 4PNWA 4K3SA 5AGVA 4N9AA 3RB9A 3L0WA 4N94A 3BEPA 4N96A 3F1VA 1UNNA 5FRQA 5FVEA 3PWEA 3QSBA 4OVFA 4MJQA 3D1EA 4PNVA 3Q4JA 4K3RA 3Q4KA 4S3IA 1OK7A 2XURA 4N98A 3Q4LA 4K3MA 3PGEB 4MJRA 4PNUA 3D1FA 4N99A 4TR7A 4K3OA 4OVGA 1MMIA 4TR8A 3P16A
chains in the Genus database with same CATH superfamily

3L0XA 4N95A 3L10A 4MJPA 2AWAA 4K3PA 4K74A 4TSZA 4N97A 4K3KA 1JQJA 4RKIA 2POLA 3L0WB 3PGEA 1VPKA 4TRTA 5AH2A 3D1GA 5AGUA 4OVHA 1JQLA 3QSBB 4TR6A 3T0PA 4K3QA 5AH4A 2AVTA 4K3LA 4PNWA 4K3SA 5AGVA 4N9AA 3RB9A 3L0WA 4N94A 3BEPA 4N96A 3F1VA 1UNNA 5FRQA 5FVEA 3PWEA 3QSBA 4OVFA 3L0XB 3L10B 4MJQA 3D1EA 4PNVA 3Q4JA 4K3RA 3Q4KA 4S3IA 1OK7A 2XURA 4N98A 3Q4LA 4K3MA 3PGEB 4MJRA 4PNUA 3D1FA 4N99A 4TR7A 4K3OA 4OVGA 1MMIA 4TR8A 3P16A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3L0X A;  4N95 A;  3L10 A;  4MJP A;  2AWA A;  4K3P A;  4K74 A;  4TSZ A;  4N97 A;  4K3K A;  1JQJ A;  4RKI A;  2POL A;  1VPK A;  4TRT A;  5AH2 A;  3D1G A;  5AGU A;  4OVH A;  1JQL A;  3QSB B;  4TR6 A;  3T0P A;  4K3Q A;  5AH4 A;  2AVT A;  4K3L A;  4PNW A;  4K3S A;  5AGV A;  4N9A A;  3RB9 A;  3L0W A;  4N94 A;  3BEP A;  4N96 A;  3F1V A;  1UNN A;  5FRQ A;  5FVE A;  3PWE A;  3QSB A;  4OVF A;  4MJQ A;  3D1E A;  4PNV A;  3Q4J A;  4K3R A;  3Q4K A;  4S3I A;  1OK7 A;  2XUR A;  4N98 A;  3Q4L A;  4K3M A;  3PGE B;  4MJR A;  4PNU A;  3D1F A;  4N99 A;  4TR7 A;  4K3O A;  4OVG A;  1MMI A;  4TR8 A;  3P16 A; 
#chains in the Genus database with same CATH topology
 3L0X A;  4N95 A;  3L10 A;  4MJP A;  2AWA A;  4K3P A;  4K74 A;  4TSZ A;  4N97 A;  4K3K A;  1JQJ A;  4RKI A;  2POL A;  3L0W B;  3PGE A;  1VPK A;  4TRT A;  5AH2 A;  3D1G A;  5AGU A;  4OVH A;  1JQL A;  3QSB B;  4TR6 A;  3T0P A;  4K3Q A;  5AH4 A;  2AVT A;  4K3L A;  4PNW A;  4K3S A;  5AGV A;  4N9A A;  3RB9 A;  3L0W A;  4N94 A;  3BEP A;  4N96 A;  3F1V A;  1UNN A;  5FRQ A;  5FVE A;  3PWE A;  3QSB A;  4OVF A;  3L0X B;  3L10 B;  4MJQ A;  3D1E A;  4PNV A;  3Q4J A;  4K3R A;  3Q4K A;  4S3I A;  1OK7 A;  2XUR A;  4N98 A;  3Q4L A;  4K3M A;  3PGE B;  4MJR A;  4PNU A;  3D1F A;  4N99 A;  4TR7 A;  4K3O A;  4OVG A;  1MMI A;  4TR8 A;  3P16 A; 
#chains in the Genus database with same CATH homology
 3L0X A;  4N95 A;  3L10 A;  4MJP A;  2AWA A;  4K3P A;  4K74 A;  4TSZ A;  4N97 A;  4K3K A;  1JQJ A;  4RKI A;  2POL A;  1VPK A;  4TRT A;  5AH2 A;  3D1G A;  5AGU A;  4OVH A;  1JQL A;  3QSB B;  4TR6 A;  3T0P A;  4K3Q A;  5AH4 A;  2AVT A;  4K3L A;  4PNW A;  4K3S A;  5AGV A;  4N9A A;  3RB9 A;  3L0W A;  4N94 A;  3BEP A;  4N96 A;  3F1V A;  1UNN A;  5FRQ A;  5FVE A;  3PWE A;  3QSB A;  4OVF A;  4MJQ A;  3D1E A;  4PNV A;  3Q4J A;  4K3R A;  3Q4K A;  4S3I A;  1OK7 A;  2XUR A;  4N98 A;  3Q4L A;  4K3M A;  3PGE B;  4MJR A;  4PNU A;  3D1F A;  4N99 A;  4TR7 A;  4K3O A;  4OVG A;  1MMI A;  4TR8 A;  3P16 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3Q4LA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations