3QSBB

Structure of e. coli poliiibeta with (z)-5-(1-((4'-fluorobiphenyl-4-yl)methoxyimino)butyl)-2,2-dimethyl-4,6-dioxocyclohexanecarbonitrile
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
366
structure length
365
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding inhibitors of the bacterial sliding clamp by design
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Escherichia coli
molecule keywords DNA polymerase III subunit beta
total genus 88
structure length 365
sequence length 366
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2011-02-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
B PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
B PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3qsbB02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3qsbB03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 3qsbB01
5AGUA 4N98A 2AVTA 4MJQA 4MJPA 4K3MA 4K3KA 3RB9A 4TSZA 3PWEA 3QSBA 2AWAA 4K3LA 4RKIA 4MJRA 1MMIA 1OK7A 4K3SA 3D1FA 4N9AA 3Q4KA 1JQLA 4K3QA 4K3PA 5FVEA 3L0XA 4S3IA 4PNVA 3L0WA 1VPKA 4N95A 3Q4JA 4N97A 5AGVA 4TRTA 4K74A 4TR7A 3Q4LA 5AH2A 4N94A 3PGEB 5FRQA 4OVHA 4N99A 3QSBB 4OVFA 1UNNA 4K3OA 4OVGA 4PNUA 3F1VA 3L10A 4TR6A 4PNWA 2POLA 3D1EA 5AH4A 3T0PA 1JQJA 3D1GA 4TR8A 3BEPA 4K3RA 2XURA 3P16A 4N96A
chains in the Genus database with same CATH superfamily
5AGUA 4N98A 2AVTA 4MJQA 4MJPA 4K3MA 4K3KA 3PGEA 3RB9A 4TSZA 3PWEA 3QSBA 2AWAA 4K3LA 4RKIA 4MJRA 1MMIA 1OK7A 4K3SA 3D1FA 4N9AA 3Q4KA 1JQLA 3L10B 4K3QA 4K3PA 5FVEA 3L0XA 4S3IA 4PNVA 3L0WA 1VPKA 4N95A 3Q4JA 4N97A 5AGVA 4TRTA 4K74A 4TR7A 3Q4LA 5AH2A 4N94A 3PGEB 5FRQA 4OVHA 4N99A 3QSBB 4OVFA 1UNNA 4K3OA 4OVGA 4PNUA 3F1VA 3L10A 4TR6A 4PNWA 2POLA 3D1EA 5AH4A 3T0PA 1JQJA 3D1GA 3L0XB 4TR8A 4K3RA 3BEPA 2XURA 3L0WB 3P16A 4N96A
chains in the Genus database with same CATH topology
5AGUA 4N98A 2AVTA 4MJQA 4MJPA 4K3MA 4K3KA 3RB9A 4TSZA 3PWEA 3QSBA 2AWAA 4K3LA 4RKIA 4MJRA 1MMIA 1OK7A 4K3SA 3D1FA 4N9AA 3Q4KA 1JQLA 4K3QA 4K3PA 5FVEA 3L0XA 4S3IA 4PNVA 3L0WA 1VPKA 4N95A 3Q4JA 4N97A 5AGVA 4TRTA 4K74A 4TR7A 3Q4LA 5AH2A 4N94A 3PGEB 5FRQA 4OVHA 4N99A 3QSBB 4OVFA 1UNNA 4K3OA 4OVGA 4PNUA 3F1VA 3L10A 4TR6A 4PNWA 2POLA 3D1EA 5AH4A 3T0PA 1JQJA 3D1GA 4TR8A 3BEPA 4K3RA 2XURA 3P16A 4N96A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AGU A;  4N98 A;  2AVT A;  4MJQ A;  4MJP A;  4K3M A;  4K3K A;  3RB9 A;  4TSZ A;  3PWE A;  3QSB A;  2AWA A;  4K3L A;  4RKI A;  4MJR A;  1MMI A;  1OK7 A;  4K3S A;  3D1F A;  4N9A A;  3Q4K A;  1JQL A;  4K3Q A;  4K3P A;  5FVE A;  3L0X A;  4S3I A;  4PNV A;  3L0W A;  1VPK A;  4N95 A;  3Q4J A;  4N97 A;  5AGV A;  4TRT A;  4K74 A;  4TR7 A;  3Q4L A;  5AH2 A;  4N94 A;  3PGE B;  5FRQ A;  4OVH A;  4N99 A;  3QSB B;  4OVF A;  1UNN A;  4K3O A;  4OVG A;  4PNU A;  3F1V A;  3L10 A;  4TR6 A;  4PNW A;  2POL A;  3D1E A;  5AH4 A;  3T0P A;  1JQJ A;  3D1G A;  4TR8 A;  3BEP A;  4K3R A;  2XUR A;  3P16 A;  4N96 A; 
#chains in the Genus database with same CATH topology
 5AGU A;  4N98 A;  2AVT A;  4MJQ A;  4MJP A;  4K3M A;  4K3K A;  3PGE A;  3RB9 A;  4TSZ A;  3PWE A;  3QSB A;  2AWA A;  4K3L A;  4RKI A;  4MJR A;  1MMI A;  1OK7 A;  4K3S A;  3D1F A;  4N9A A;  3Q4K A;  1JQL A;  3L10 B;  4K3Q A;  4K3P A;  5FVE A;  3L0X A;  4S3I A;  4PNV A;  3L0W A;  1VPK A;  4N95 A;  3Q4J A;  4N97 A;  5AGV A;  4TRT A;  4K74 A;  4TR7 A;  3Q4L A;  5AH2 A;  4N94 A;  3PGE B;  5FRQ A;  4OVH A;  4N99 A;  3QSB B;  4OVF A;  1UNN A;  4K3O A;  4OVG A;  4PNU A;  3F1V A;  3L10 A;  4TR6 A;  4PNW A;  2POL A;  3D1E A;  5AH4 A;  3T0P A;  1JQJ A;  3D1G A;  3L0X B;  4TR8 A;  4K3R A;  3BEP A;  2XUR A;  3L0W B;  3P16 A;  4N96 A; 
#chains in the Genus database with same CATH homology
 5AGU A;  4N98 A;  2AVT A;  4MJQ A;  4MJP A;  4K3M A;  4K3K A;  3RB9 A;  4TSZ A;  3PWE A;  3QSB A;  2AWA A;  4K3L A;  4RKI A;  4MJR A;  1MMI A;  1OK7 A;  4K3S A;  3D1F A;  4N9A A;  3Q4K A;  1JQL A;  4K3Q A;  4K3P A;  5FVE A;  3L0X A;  4S3I A;  4PNV A;  3L0W A;  1VPK A;  4N95 A;  3Q4J A;  4N97 A;  5AGV A;  4TRT A;  4K74 A;  4TR7 A;  3Q4L A;  5AH2 A;  4N94 A;  3PGE B;  5FRQ A;  4OVH A;  4N99 A;  3QSB B;  4OVF A;  1UNN A;  4K3O A;  4OVG A;  4PNU A;  3F1V A;  3L10 A;  4TR6 A;  4PNW A;  2POL A;  3D1E A;  5AH4 A;  3T0P A;  1JQJ A;  3D1G A;  4TR8 A;  3BEP A;  4K3R A;  2XUR A;  3P16 A;  4N96 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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