3TQGA

Structure of the 2-methylcitrate synthase (prpc) from coxiella burnetii
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
360
structure length
360
Chain Sequence
AGETSIATVGKEGHGLTYRGYRIEDLAANATFEEVAYLLLKNKLPTKSELDAYTKKLVNLRSLPPALKDTLERIPASSHPMDVMRTGCSMLGNLEPENGFENEQNIADRLVAIFPAIQCYWYHYSHHGKRIDTELDDLTLAGYFLHLLLGKKAAQMAIDCMNASLILYAEHEFNASTFAARVCSATLSDIYSAVTAAIATLRGPLHGGANEAAMDLIMLYKTPSEAIAGIKRKLANKELIMGFGHAVYRERDPRNAIIKSWAQKLAPNAADGYLFDISDAIENTMQDEKKLFPNLDFYSATAYHFLNIPTKLFTPIFVMSRVTGWCAHIFEQRKDNRIIRPNADYIGPEEQGWVPIEKRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural genomics for drug design against the pathogen Coxiella burnetii.
pubmed doi rcsb
molecule tags Transferase
source organism Coxiella burnetii
molecule keywords 2-methylcitrate synthase
total genus 115
structure length 360
sequence length 360
chains with identical sequence B
ec nomenclature ec 2.3.3.5: 2-methylcitrate synthase.
pdb deposition date 2011-09-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 3tqgA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 3tqgA01
2IBPA 4YBOA 3HWKA 6CSCA 4JAEA 1O7XA 1AMZA 1CSSA 5CTSA 1CSCA 1CTSA 5CSCB 2IFCA 3O8JA 2CSCA 3TQGA 1A59A 1NXGA 2CTSA 4JADA 1OWCA 5CSCA 1VGPA 4G6BA 4JAGA 1OWBA 1IOMA 3CSCA 4JAFA 4XGHA 2H12A 1NXEA 1CSIA 1CSHA 1VGMA 2C6XA 2P2WA 4CTSA 4CSCA 4TVMA 1AJ8A 1CSRA 4E6YA 1IXEA 1AL6A 2R26A 6CTSA 2R9EA 3ENJA 3MSUA
chains in the Genus database with same CATH superfamily
2IBPA 4YBOA 3HWKA 6CSCA 4JAEA 1O7XA 1AMZA 1CSSA 5CTSA 1CSCA 1CTSA 5CSCB 2IFCA 3O8JA 2CSCA 3TQGA 1A59A 1NXGA 2CTSA 4JADA 1OWCA 5CSCA 1VGPA 4G6BA 4JAGA 1OWBA 1IOMA 3CSCA 4JAFA 4XGHA 2H12A 1NXEA 1CSIA 1CSHA 1VGMA 2C6XA 2P2WA 4TVMA 4CTSA 4CSCA 1AJ8A 1CSRA 4E6YA 1IXEA 1AL6A 2R26A 6CTSA 2R9EA 3ENJA 3MSUA
chains in the Genus database with same CATH topology
2IBPA 4YBOA 3HWKA 6CSCA 4JAEA 1O7XA 1AMZA 1CSSA 5CTSA 1CSCA 1CTSA 5CSCB 2IFCA 3O8JA 2CSCA 3TQGA 1A59A 1NXGA 2CTSA 4JADA 1OWCA 5CSCA 1VGPA 4G6BA 4JAGA 1OWBA 1IOMA 3CSCA 4JAFA 4XGHA 2H12A 1NXEA 1CSIA 1CSHA 1VGMA 2C6XA 2P2WA 4CTSA 4CSCA 4TVMA 1AJ8A 1CSRA 4E6YA 1IXEA 1AL6A 2R26A 6CTSA 2R9EA 3ENJA 3MSUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IBP A;  4YBO A;  3HWK A;  6CSC A;  4JAE A;  1O7X A;  1AMZ A;  1CSS A;  5CTS A;  1CSC A;  1CTS A;  5CSC B;  2IFC A;  3O8J A;  2CSC A;  3TQG A;  1A59 A;  1NXG A;  2CTS A;  4JAD A;  1OWC A;  5CSC A;  1VGP A;  4G6B A;  4JAG A;  1OWB A;  1IOM A;  3CSC A;  4JAF A;  4XGH A;  2H12 A;  1NXE A;  1CSI A;  1CSH A;  1VGM A;  2C6X A;  2P2W A;  4CTS A;  4CSC A;  4TVM A;  1AJ8 A;  1CSR A;  4E6Y A;  1IXE A;  1AL6 A;  2R26 A;  6CTS A;  2R9E A;  3ENJ A;  3MSU A; 
#chains in the Genus database with same CATH topology
 2IBP A;  4YBO A;  3HWK A;  6CSC A;  4JAE A;  1O7X A;  1AMZ A;  1CSS A;  5CTS A;  1CSC A;  1CTS A;  5CSC B;  2IFC A;  3O8J A;  2CSC A;  3TQG A;  1A59 A;  1NXG A;  2CTS A;  4JAD A;  1OWC A;  5CSC A;  1VGP A;  4G6B A;  4JAG A;  1OWB A;  1IOM A;  3CSC A;  4JAF A;  4XGH A;  2H12 A;  1NXE A;  1CSI A;  1CSH A;  1VGM A;  2C6X A;  2P2W A;  4TVM A;  4CTS A;  4CSC A;  1AJ8 A;  1CSR A;  4E6Y A;  1IXE A;  1AL6 A;  2R26 A;  6CTS A;  2R9E A;  3ENJ A;  3MSU A; 
#chains in the Genus database with same CATH homology
 2IBP A;  4YBO A;  3HWK A;  6CSC A;  4JAE A;  1O7X A;  1AMZ A;  1CSS A;  5CTS A;  1CSC A;  1CTS A;  5CSC B;  2IFC A;  3O8J A;  2CSC A;  3TQG A;  1A59 A;  1NXG A;  2CTS A;  4JAD A;  1OWC A;  5CSC A;  1VGP A;  4G6B A;  4JAG A;  1OWB A;  1IOM A;  3CSC A;  4JAF A;  4XGH A;  2H12 A;  1NXE A;  1CSI A;  1CSH A;  1VGM A;  2C6X A;  2P2W A;  4CTS A;  4CSC A;  4TVM A;  1AJ8 A;  1CSR A;  4E6Y A;  1IXE A;  1AL6 A;  2R26 A;  6CTS A;  2R9E A;  3ENJ A;  3MSU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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