3W6WA

Crystal structure of melb holo-protyrosinase from asperugillus oryzae
Total Genus 209
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
209
sequence length
617
structure length
583
Chain Sequence
GSPYLITGIPKDPKHPLPIRKDIDDWYLEQTSAGSNRIQLTLFVEALTVIQNRPLNDQLSYFRLAGIHGAPWTEWDGVPGGQKDSKGNPTGFCVHNNYTFPTWHRVYVTLYEQVIYEAMLDFIKQNVPQNGKADWENEAKQWRLPYWDFARFARGDELRLPILVTMPMVKVLVPGQPGKQLSKPNPLYRFQMQTLMGTLERPYAITSQKTEEHGWSFDLPFDKCQSTTKYGLLENYNADVWADGGQNWLRANLALNEHPWYQNLDGWDSVPTLQDMTFRLLTTGGLNWGEFSSTRYDDAPKNWMNLEAIHNNVHNWVGGFMFSRPGRHDLKLWGAGHMSSVPVAAYDPIFWLHHCNIDRLTAIWQTVNSGSWFNDDKSKVSKDDDLRPFHRFCEKTRKVVFFRSDDVKDWRSLNYDYAITKDASRIRKEISDLYGQRTKEVYKDFGEEDYILSIRYSRYALGGKPFQINIFFGDVDGKDFYDARSQNFVGSVFNFSGSLEDSNCDKCAVLSVSQLPARLAVHYYKKQNKGEVPTPRYVVVNSQGKAEAEVKVEVALHKTEGTFYDYRRVADGKRAEVDDAYRA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structures of Copper-depleted and Copper-bound Fungal Pro-tyrosinase: INSIGHTS INTO ENDOGENOUS CYSTEINE-DEPENDENT COPPER INCORPORATION
doi rcsb
molecule tags Oxidoreductase
source organism Aspergillus oryzae
molecule keywords Tyrosinase
total genus 209
structure length 583
sequence length 617
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
A PF18132 Tyosinase_C Tyosinase C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 3w6wA01
2.60.310.20 Mainly Beta Sandwich Hemocyanin; Chain: A, domain 2 Hemocyanin; Chain: A, domain 2 3w6wA02
2ZMZA 5I38A 2ZWEA 1BUGA 3HHSA 2AHKA 3AX0A 4Z10A 1NOLA 2P3XA 4J3PA 3NTMA 1WX5A 2ZWGA 3W6WA 1HC1A 3AWXA 4HD7A 1WXCA 4HD4A 3WJMA 3AWUA 4J6VA 3AWSA 2ZWFA 1LNLA 4L37B 3AWTA 4P6RA 3NQ0A 1BT1A 3QJOA 3NPYA 3NQ1A 2ZMXA 4J6UA 4J6TA 1OXYA 4OUAB 4D87A 1LLAA 2ZMYA 4L37A 4P6SA 3WKYA 4Z0ZA 3AWWA 5I3BA 5CE9A 2Y9WA 3AWYA 4J3RA 4J3QA 4OUAA 4HD6A 1JS8A 2ZWDA 1WX4A 1LL1A 3HHSB 3GWJA 1BT3A 5I3AA 2AHLA 4P6TA 3W6QA 1HCYA 3NM8A 3NQ5A 4YZWA 3AWZA 2Y9XA 3WJMB 3AWVA 1BT2A 1WX2A 4Z0YA
chains in the Genus database with same CATH superfamily
2ZMZA 5I38A 2ZWEA 1BUGA 3HHSA 2AHKA 3AX0A 4Z10A 1NOLA 2P3XA 4J3PA 3NTMA 1WX5A 2ZWGA 3W6WA 1HC1A 3AWXA 4HD7A 1WXCA 4HD4A 3WJMA 3AWUA 4J6VA 3AWSA 2ZWFA 1LNLA 4L37B 3AWTA 4P6RA 3NQ0A 1BT1A 3QJOA 3NPYA 3NQ1A 2ZMXA 4J6UA 4J6TA 1OXYA 4OUAB 4D87A 1LLAA 2ZMYA 4L37A 4P6SA 3WKYA 4Z0ZA 3AWWA 5I3BA 5CE9A 2Y9WA 3AWYA 4J3RA 4J3QA 4OUAA 4HD6A 1JS8A 2ZWDA 1WX4A 1LL1A 3HHSB 3GWJA 1BT3A 5I3AA 2AHLA 4P6TA 3W6QA 1HCYA 3NM8A 3NQ5A 4YZWA 3AWZA 2Y9XA 3WJMB 3AWVA 1BT2A 1WX2A 4Z0YA
chains in the Genus database with same CATH topology
2ZMZA 5I38A 2ZWEA 1BUGA 3HHSA 2AHKA 3AX0A 4Z10A 1NOLA 2P3XA 4J3PA 3NTMA 1WX5A 2ZWGA 3W6WA 1HC1A 3AWXA 4HD7A 1WXCA 4HD4A 3WJMA 3AWUA 4J6VA 3AWSA 2ZWFA 1LNLA 4L37B 3AWTA 4P6RA 3NQ0A 1BT1A 3QJOA 3NPYA 3NQ1A 2ZMXA 4J6UA 4J6TA 1OXYA 4OUAB 4D87A 1LLAA 2ZMYA 4L37A 4P6SA 3WKYA 4Z0ZA 3AWWA 5I3BA 5CE9A 2Y9WA 3AWYA 4J3RA 4J3QA 4OUAA 4HD6A 1JS8A 2ZWDA 1WX4A 1LL1A 3HHSB 3GWJA 1BT3A 5I3AA 2AHLA 4P6TA 3W6QA 1HCYA 3NM8A 3NQ5A 4YZWA 3AWZA 2Y9XA 3WJMB 3AWVA 1BT2A 1WX2A 4Z0YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZMZ A;  5I38 A;  2ZWE A;  1BUG A;  3HHS A;  2AHK A;  3AX0 A;  4Z10 A;  1NOL A;  2P3X A;  4J3P A;  3NTM A;  1WX5 A;  2ZWG A;  3W6W A;  1HC1 A;  3AWX A;  4HD7 A;  1WXC A;  4HD4 A;  3WJM A;  3AWU A;  4J6V A;  3AWS A;  2ZWF A;  1LNL A;  4L37 B;  3AWT A;  4P6R A;  3NQ0 A;  1BT1 A;  3QJO A;  3NPY A;  3NQ1 A;  2ZMX A;  4J6U A;  4J6T A;  1OXY A;  4OUA B;  4D87 A;  1LLA A;  2ZMY A;  4L37 A;  4P6S A;  3WKY A;  4Z0Z A;  3AWW A;  5I3B A;  5CE9 A;  2Y9W A;  3AWY A;  4J3R A;  4J3Q A;  4OUA A;  4HD6 A;  1JS8 A;  2ZWD A;  1WX4 A;  1LL1 A;  3HHS B;  3GWJ A;  1BT3 A;  5I3A A;  2AHL A;  4P6T A;  3W6Q A;  1HCY A;  3NM8 A;  3NQ5 A;  4YZW A;  3AWZ A;  2Y9X A;  3WJM B;  3AWV A;  1BT2 A;  1WX2 A;  4Z0Y A; 
#chains in the Genus database with same CATH topology
 2ZMZ A;  5I38 A;  2ZWE A;  1BUG A;  3HHS A;  2AHK A;  3AX0 A;  4Z10 A;  1NOL A;  2P3X A;  4J3P A;  3NTM A;  1WX5 A;  2ZWG A;  3W6W A;  1HC1 A;  3AWX A;  4HD7 A;  1WXC A;  4HD4 A;  3WJM A;  3AWU A;  4J6V A;  3AWS A;  2ZWF A;  1LNL A;  4L37 B;  3AWT A;  4P6R A;  3NQ0 A;  1BT1 A;  3QJO A;  3NPY A;  3NQ1 A;  2ZMX A;  4J6U A;  4J6T A;  1OXY A;  4OUA B;  4D87 A;  1LLA A;  2ZMY A;  4L37 A;  4P6S A;  3WKY A;  4Z0Z A;  3AWW A;  5I3B A;  5CE9 A;  2Y9W A;  3AWY A;  4J3R A;  4J3Q A;  4OUA A;  4HD6 A;  1JS8 A;  2ZWD A;  1WX4 A;  1LL1 A;  3HHS B;  3GWJ A;  1BT3 A;  5I3A A;  2AHL A;  4P6T A;  3W6Q A;  1HCY A;  3NM8 A;  3NQ5 A;  4YZW A;  3AWZ A;  2Y9X A;  3WJM B;  3AWV A;  1BT2 A;  1WX2 A;  4Z0Y A; 
#chains in the Genus database with same CATH homology
 2ZMZ A;  5I38 A;  2ZWE A;  1BUG A;  3HHS A;  2AHK A;  3AX0 A;  4Z10 A;  1NOL A;  2P3X A;  4J3P A;  3NTM A;  1WX5 A;  2ZWG A;  3W6W A;  1HC1 A;  3AWX A;  4HD7 A;  1WXC A;  4HD4 A;  3WJM A;  3AWU A;  4J6V A;  3AWS A;  2ZWF A;  1LNL A;  4L37 B;  3AWT A;  4P6R A;  3NQ0 A;  1BT1 A;  3QJO A;  3NPY A;  3NQ1 A;  2ZMX A;  4J6U A;  4J6T A;  1OXY A;  4OUA B;  4D87 A;  1LLA A;  2ZMY A;  4L37 A;  4P6S A;  3WKY A;  4Z0Z A;  3AWW A;  5I3B A;  5CE9 A;  2Y9W A;  3AWY A;  4J3R A;  4J3Q A;  4OUA A;  4HD6 A;  1JS8 A;  2ZWD A;  1WX4 A;  1LL1 A;  3HHS B;  3GWJ A;  1BT3 A;  5I3A A;  2AHL A;  4P6T A;  3W6Q A;  1HCY A;  3NM8 A;  3NQ5 A;  4YZW A;  3AWZ A;  2Y9X A;  3WJM B;  3AWV A;  1BT2 A;  1WX2 A;  4Z0Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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