3W6WA

Crystal structure of melb holo-protyrosinase from asperugillus oryzae
Total Genus 209
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
209
sequence length
617
structure length
583
Chain Sequence
GSPYLITGIPKDPKHPLPIRKDIDDWYLEQTSAGSNRIQLTLFVEALTVIQNRPLNDQLSYFRLAGIHGAPWTEWDGVPGGQKDSKGNPTGFCVHNNYTFPTWHRVYVTLYEQVIYEAMLDFIKQNVPQNGKADWENEAKQWRLPYWDFARFARGDELRLPILVTMPMVKVLVPGQPGKQLSKPNPLYRFQMQTLMGTLERPYAITSQKTEEHGWSFDLPFDKCQSTTKYGLLENYNADVWADGGQNWLRANLALNEHPWYQNLDGWDSVPTLQDMTFRLLTTGGLNWGEFSSTRYDDAPKNWMNLEAIHNNVHNWVGGFMFSRPGRHDLKLWGAGHMSSVPVAAYDPIFWLHHCNIDRLTAIWQTVNSGSWFNDDKSKVSKDDDLRPFHRFCEKTRKVVFFRSDDVKDWRSLNYDYAITKDASRIRKEISDLYGQRTKEVYKDFGEEDYILSIRYSRYALGGKPFQINIFFGDVDGKDFYDARSQNFVGSVFNFSGSLEDSNCDKCAVLSVSQLPARLAVHYYKKQNKGEVPTPRYVVVNSQGKAEAEVKVEVALHKTEGTFYDYRRVADGKRAEVDDAYRA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structures of Copper-depleted and Copper-bound Fungal Pro-tyrosinase: INSIGHTS INTO ENDOGENOUS CYSTEINE-DEPENDENT COPPER INCORPORATION
doi rcsb
molecule tags Oxidoreductase
source organism Aspergillus oryzae
molecule keywords Tyrosinase
total genus 209
structure length 583
sequence length 617
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
A PF18132 Tyosinase_C Tyosinase C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 3w6wA01
2.60.310.20 Mainly Beta Sandwich Hemocyanin; Chain: A, domain 2 Hemocyanin; Chain: A, domain 2 3w6wA02
3AWUA 2Y9WA 4J6TA 2ZMYA 1WX2A 3WJMB 3NQ5A 4Z0YA 3NTMA 4D87A 1WX5A 1BT3A 4HD7A 2ZMZA 4P6SA 3GWJA 3QJOA 4HD4A 4L37A 1LL1A 2AHKA 1WXCA 1HCYA 2ZWGA 2P3XA 3AX0A 5I38A 1LLAA 3AWXA 1NOLA 4Z0ZA 2ZWFA 3W6QA 3AWSA 1BT2A 4OUAB 4J6UA 3NQ1A 3AWWA 3AWZA 4YZWA 3NM8A 4Z10A 4J3PA 2ZWEA 5CE9A 4L37B 3AWVA 2AHLA 3HHSB 1BUGA 4HD6A 4P6TA 1BT1A 3NPYA 3WJMA 1WX4A 1HC1A 4OUAA 2ZMXA 3WKYA 3W6WA 4P6RA 3AWYA 3NQ0A 4J6VA 2Y9XA 4J3RA 5I3BA 5I3AA 4J3QA 1LNLA 1JS8A 1OXYA 2ZWDA 3HHSA 3AWTA
chains in the Genus database with same CATH superfamily
3AWUA 2Y9WA 4J6TA 2ZMYA 1WX2A 3WJMB 3NQ5A 4Z0YA 3NTMA 4D87A 1WX5A 1BT3A 4HD7A 2ZMZA 4P6SA 3GWJA 3QJOA 4HD4A 4L37A 1LL1A 2AHKA 1WXCA 1HCYA 2ZWGA 2P3XA 3AX0A 5I38A 1LLAA 3AWXA 1NOLA 4Z0ZA 2ZWFA 3W6QA 3AWSA 1BT2A 4OUAB 4J6UA 3NQ1A 3AWWA 3AWZA 4YZWA 3NM8A 4Z10A 4J3PA 2ZWEA 5CE9A 4L37B 3AWVA 2AHLA 3HHSB 1BUGA 4HD6A 4P6TA 1BT1A 3NPYA 3WJMA 1WX4A 1HC1A 4OUAA 2ZMXA 3WKYA 3W6WA 4P6RA 3AWYA 3NQ0A 4J6VA 2Y9XA 4J3RA 5I3BA 5I3AA 4J3QA 1LNLA 1JS8A 1OXYA 2ZWDA 3HHSA 3AWTA
chains in the Genus database with same CATH topology
3AWUA 2Y9WA 4J6TA 2ZMYA 1WX2A 3WJMB 3NQ5A 4Z0YA 3NTMA 4D87A 1WX5A 1BT3A 4HD7A 2ZMZA 4P6SA 3GWJA 3QJOA 4HD4A 4L37A 1LL1A 2AHKA 1WXCA 1HCYA 2ZWGA 2P3XA 3AX0A 5I38A 1LLAA 3AWXA 1NOLA 4Z0ZA 2ZWFA 3W6QA 3AWSA 1BT2A 4OUAB 4J6UA 3NQ1A 3AWWA 3AWZA 4YZWA 3NM8A 4Z10A 4J3PA 2ZWEA 5CE9A 4L37B 3AWVA 2AHLA 3HHSB 1BUGA 4HD6A 4P6TA 1BT1A 3NPYA 3WJMA 1WX4A 1HC1A 4OUAA 2ZMXA 3WKYA 3W6WA 4P6RA 3AWYA 3NQ0A 4J6VA 2Y9XA 4J3RA 5I3BA 5I3AA 4J3QA 1LNLA 1JS8A 1OXYA 2ZWDA 3HHSA 3AWTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AWU A;  2Y9W A;  4J6T A;  2ZMY A;  1WX2 A;  3WJM B;  3NQ5 A;  4Z0Y A;  3NTM A;  4D87 A;  1WX5 A;  1BT3 A;  4HD7 A;  2ZMZ A;  4P6S A;  3GWJ A;  3QJO A;  4HD4 A;  4L37 A;  1LL1 A;  2AHK A;  1WXC A;  1HCY A;  2ZWG A;  2P3X A;  3AX0 A;  5I38 A;  1LLA A;  3AWX A;  1NOL A;  4Z0Z A;  2ZWF A;  3W6Q A;  3AWS A;  1BT2 A;  4OUA B;  4J6U A;  3NQ1 A;  3AWW A;  3AWZ A;  4YZW A;  3NM8 A;  4Z10 A;  4J3P A;  2ZWE A;  5CE9 A;  4L37 B;  3AWV A;  2AHL A;  3HHS B;  1BUG A;  4HD6 A;  4P6T A;  1BT1 A;  3NPY A;  3WJM A;  1WX4 A;  1HC1 A;  4OUA A;  2ZMX A;  3WKY A;  3W6W A;  4P6R A;  3AWY A;  3NQ0 A;  4J6V A;  2Y9X A;  4J3R A;  5I3B A;  5I3A A;  4J3Q A;  1LNL A;  1JS8 A;  1OXY A;  2ZWD A;  3HHS A;  3AWT A; 
#chains in the Genus database with same CATH topology
 3AWU A;  2Y9W A;  4J6T A;  2ZMY A;  1WX2 A;  3WJM B;  3NQ5 A;  4Z0Y A;  3NTM A;  4D87 A;  1WX5 A;  1BT3 A;  4HD7 A;  2ZMZ A;  4P6S A;  3GWJ A;  3QJO A;  4HD4 A;  4L37 A;  1LL1 A;  2AHK A;  1WXC A;  1HCY A;  2ZWG A;  2P3X A;  3AX0 A;  5I38 A;  1LLA A;  3AWX A;  1NOL A;  4Z0Z A;  2ZWF A;  3W6Q A;  3AWS A;  1BT2 A;  4OUA B;  4J6U A;  3NQ1 A;  3AWW A;  3AWZ A;  4YZW A;  3NM8 A;  4Z10 A;  4J3P A;  2ZWE A;  5CE9 A;  4L37 B;  3AWV A;  2AHL A;  3HHS B;  1BUG A;  4HD6 A;  4P6T A;  1BT1 A;  3NPY A;  3WJM A;  1WX4 A;  1HC1 A;  4OUA A;  2ZMX A;  3WKY A;  3W6W A;  4P6R A;  3AWY A;  3NQ0 A;  4J6V A;  2Y9X A;  4J3R A;  5I3B A;  5I3A A;  4J3Q A;  1LNL A;  1JS8 A;  1OXY A;  2ZWD A;  3HHS A;  3AWT A; 
#chains in the Genus database with same CATH homology
 3AWU A;  2Y9W A;  4J6T A;  2ZMY A;  1WX2 A;  3WJM B;  3NQ5 A;  4Z0Y A;  3NTM A;  4D87 A;  1WX5 A;  1BT3 A;  4HD7 A;  2ZMZ A;  4P6S A;  3GWJ A;  3QJO A;  4HD4 A;  4L37 A;  1LL1 A;  2AHK A;  1WXC A;  1HCY A;  2ZWG A;  2P3X A;  3AX0 A;  5I38 A;  1LLA A;  3AWX A;  1NOL A;  4Z0Z A;  2ZWF A;  3W6Q A;  3AWS A;  1BT2 A;  4OUA B;  4J6U A;  3NQ1 A;  3AWW A;  3AWZ A;  4YZW A;  3NM8 A;  4Z10 A;  4J3P A;  2ZWE A;  5CE9 A;  4L37 B;  3AWV A;  2AHL A;  3HHS B;  1BUG A;  4HD6 A;  4P6T A;  1BT1 A;  3NPY A;  3WJM A;  1WX4 A;  1HC1 A;  4OUA A;  2ZMX A;  3WKY A;  3W6W A;  4P6R A;  3AWY A;  3NQ0 A;  4J6V A;  2Y9X A;  4J3R A;  5I3B A;  5I3A A;  4J3Q A;  1LNL A;  1JS8 A;  1OXY A;  2ZWD A;  3HHS A;  3AWT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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