3CCRU

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model.
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 6
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
U PF01246 Ribosomal_L24e Ribosomal protein L24e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3ccrU00
1K8AV 1VQ7U 1YHQU 3CC2U 1VQMU 3CMAU 1W2BT 1VQKU 3CXCT 1VQNU 1K9MV 1YI2U 1NJIV 3CCMU 1YJWU 3CCSU 1KD1V 1VQOU 2OTJU 1QVGT 2QA4U 3I55U 1Q7YV 1JJ2T 1QVFT 1YITU 1Q81V 5AN9G 1VQ9U 3CCQU 1M90V 3CD6U 3G71U 3I56U 1N8RV 1VQLU 1KC8V 3G4SU 3CCRU 1VQ4U 3CCEU 1M1KV 3CMEU 1YJNU 2OTLU 1S72U 1YJ9U 3CC4U 1VQPU 3G6EU 1K73V 1VQ8U 3CPWT 1VQ5U 3CCLU 3CCVU 3CCUU 1Q82V 1YIJU 1Q86V 3CCJU 3CC7U 1KQST 1VQ6U 2QEXU 3OW2T
chains in the Genus database with same CATH superfamily
1YHQU 3CC2U 1W2BT 1YI2U 1KD1V 3CD6U 5AN9G 1N8RV 1KC8V 1YJNU 2OTLU 1S72U 3AO0A 1VQ8U 4UY8X 3CPWT 1VQ5U 1Q86V 3CCUU 1YIJU 2QEZA 1VQMU 1VQNU 3CCMU 3CCSU 1VQOU 2QA4U 3I55U 1JJ2T 3ABRA 3G71U 1M1KV 1YJ9U 3CCVU 3CC7U 3CCJU 3ANYA 1VQKU 1NJIV 3ABOA 5H1SY 2OTJU 5DM6U 1QVGT 1QVFT 1YITU 1Q81V 1VQ9U 3CCQU 1JJDA 3CCRU 1VQ4U 3CMEU 3CC4U 1VQPU 3G6EU 1K73V 3CCLU 1KQST 3OW2T 1K8AV 1VQ7U 3CMAU 3J7ZX 3CXCT 1K9MV 1YJWU 3ABSA 1Q7YV 1M90V 3I56U 1VQLU 3G4SU 3CCEU 5MLCY 3ABQA 1Q82V 1VQ6U 2QEXU 2JZ6A
chains in the Genus database with same CATH topology
1K8AV 1VQ7U 1YHQU 3CC2U 1VQMU 3CMAU 1W2BT 1VQKU 3CXCT 1VQNU 1K9MV 1YI2U 1NJIV 3CCMU 1YJWU 3CCSU 1KD1V 1VQOU 2OTJU 1QVGT 2QA4U 3I55U 1Q7YV 1JJ2T 1QVFT 1YITU 1Q81V 5AN9G 1VQ9U 3CCQU 1M90V 3CD6U 3G71U 1JJDA 3I56U 1N8RV 1VQLU 1KC8V 3G4SU 3CCRU 1VQ4U 3CCEU 1M1KV 3CMEU 1YJNU 2OTLU 1S72U 1YJ9U 3CC4U 1VQPU 3G6EU 1K73V 1VQ8U 3CPWT 1VQ5U 3CCLU 3CCVU 3CCUU 1Q82V 1YIJU 1Q86V 3CCJU 3CC7U 1KQST 1VQ6U 2QEXU 3OW2T
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K8A V;  1VQ7 U;  1YHQ U;  3CC2 U;  1VQM U;  3CMA U;  1W2B T;  1VQK U;  3CXC T;  1VQN U;  1K9M V;  1YI2 U;  1NJI V;  3CCM U;  1YJW U;  3CCS U;  1KD1 V;  1VQO U;  2OTJ U;  1QVG T;  2QA4 U;  3I55 U;  1Q7Y V;  1JJ2 T;  1QVF T;  1YIT U;  1Q81 V;  5AN9 G;  1VQ9 U;  3CCQ U;  1M90 V;  3CD6 U;  3G71 U;  3I56 U;  1N8R V;  1VQL U;  1KC8 V;  3G4S U;  3CCR U;  1VQ4 U;  3CCE U;  1M1K V;  3CME U;  1YJN U;  2OTL U;  1S72 U;  1YJ9 U;  3CC4 U;  1VQP U;  3G6E U;  1K73 V;  1VQ8 U;  3CPW T;  1VQ5 U;  3CCL U;  3CCV U;  3CCU U;  1Q82 V;  1YIJ U;  1Q86 V;  3CCJ U;  3CC7 U;  1KQS T;  1VQ6 U;  2QEX U;  3OW2 T; 
#chains in the Genus database with same CATH topology
 1YHQ U;  3CC2 U;  1W2B T;  1YI2 U;  1KD1 V;  3CD6 U;  5AN9 G;  1N8R V;  1KC8 V;  1YJN U;  2OTL U;  1S72 U;  3AO0 A;  1VQ8 U;  4UY8 X;  3CPW T;  1VQ5 U;  1Q86 V;  3CCU U;  1YIJ U;  2QEZ A;  1VQM U;  1VQN U;  3CCM U;  3CCS U;  1VQO U;  2QA4 U;  3I55 U;  1JJ2 T;  3ABR A;  3G71 U;  1M1K V;  1YJ9 U;  3CCV U;  3CC7 U;  3CCJ U;  3ANY A;  1VQK U;  1NJI V;  3ABO A;  5H1S Y;  2OTJ U;  5DM6 U;  1QVG T;  1QVF T;  1YIT U;  1Q81 V;  1VQ9 U;  3CCQ U;  1JJD A;  3CCR U;  1VQ4 U;  3CME U;  3CC4 U;  1VQP U;  3G6E U;  1K73 V;  3CCL U;  1KQS T;  3OW2 T;  1K8A V;  1VQ7 U;  3CMA U;  3J7Z X;  3CXC T;  1K9M V;  1YJW U;  3ABS A;  1Q7Y V;  1M90 V;  3I56 U;  1VQL U;  3G4S U;  3CCE U;  5MLC Y;  3ABQ A;  1Q82 V;  1VQ6 U;  2QEX U;  2JZ6 A; 
#chains in the Genus database with same CATH homology
 1K8A V;  1VQ7 U;  1YHQ U;  3CC2 U;  1VQM U;  3CMA U;  1W2B T;  1VQK U;  3CXC T;  1VQN U;  1K9M V;  1YI2 U;  1NJI V;  3CCM U;  1YJW U;  3CCS U;  1KD1 V;  1VQO U;  2OTJ U;  1QVG T;  2QA4 U;  3I55 U;  1Q7Y V;  1JJ2 T;  1QVF T;  1YIT U;  1Q81 V;  5AN9 G;  1VQ9 U;  3CCQ U;  1M90 V;  3CD6 U;  3G71 U;  1JJD A;  3I56 U;  1N8R V;  1VQL U;  1KC8 V;  3G4S U;  3CCR U;  1VQ4 U;  3CCE U;  1M1K V;  3CME U;  1YJN U;  2OTL U;  1S72 U;  1YJ9 U;  3CC4 U;  1VQP U;  3G6E U;  1K73 V;  1VQ8 U;  3CPW T;  1VQ5 U;  3CCL U;  3CCV U;  3CCU U;  1Q82 V;  1YIJ U;  1Q86 V;  3CCJ U;  3CC7 U;  1KQS T;  1VQ6 U;  2QEX U;  3OW2 T; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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