4CSCA

Structure of ternary complexes of citrate synthase with d-and l-malate: mechanistic implications
Total Genus 144
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
144
sequence length
433
structure length
429
Chain Sequence
ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGGGEPLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAAGADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYKIVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 1.9-A structures of ternary complexes of citrate synthase with D- and L-malate: mechanistic implications.
pubmed doi rcsb
molecule tags Oxo-acid-lyase
source organism Gallus gallus
molecule keywords CITRATE SYNTHASE
total genus 144
structure length 429
sequence length 433
ec nomenclature ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date 1990-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 4cscA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 4cscA01
1VGMA 1CSSA 4E6YA 3MSUA 1AJ8A 1AMZA 1NXGA 1CSCA 3HWKA 4CSCA 2C6XA 1IXEA 3ENJA 5CSCA 4YBOA 1O7XA 2P2WA 1CTSA 1CSHA 2R9EA 6CTSA 2IBPA 4JADA 2CTSA 3TQGA 2H12A 1NXEA 2IFCA 1VGPA 2R26A 6CSCA 4CTSA 2CSCA 1AL6A 1IOMA 4TVMA 1A59A 1OWCA 1CSIA 3O8JA 4JAEA 5CSCB 4JAGA 4JAFA 1OWBA 3CSCA 1CSRA 4XGHA 5CTSA 4G6BA
chains in the Genus database with same CATH superfamily
1VGMA 1CSSA 4E6YA 3MSUA 1AJ8A 1AMZA 1NXGA 1CSCA 3HWKA 4CSCA 2C6XA 1IXEA 3ENJA 5CSCA 4YBOA 1O7XA 2P2WA 1CTSA 1CSHA 2R9EA 6CTSA 2IBPA 4JADA 2CTSA 3TQGA 2H12A 1NXEA 2IFCA 1VGPA 2R26A 6CSCA 4CTSA 2CSCA 1AL6A 1IOMA 4TVMA 1A59A 1OWCA 1CSIA 3O8JA 4JAEA 5CSCB 4JAGA 4JAFA 1OWBA 3CSCA 1CSRA 4XGHA 5CTSA 4G6BA
chains in the Genus database with same CATH topology
1VGMA 1CSSA 4E6YA 3MSUA 1AJ8A 1AMZA 1NXGA 1CSCA 3HWKA 4CSCA 2C6XA 1IXEA 3ENJA 5CSCA 4YBOA 1O7XA 2P2WA 1CTSA 1CSHA 2R9EA 6CTSA 2IBPA 4JADA 2CTSA 3TQGA 2H12A 1NXEA 2IFCA 1VGPA 2R26A 6CSCA 4CTSA 2CSCA 1AL6A 1IOMA 4TVMA 1A59A 1OWCA 1CSIA 3O8JA 4JAEA 5CSCB 4JAGA 4JAFA 1OWBA 3CSCA 1CSRA 4XGHA 5CTSA 4G6BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VGM A;  1CSS A;  4E6Y A;  3MSU A;  1AJ8 A;  1AMZ A;  1NXG A;  1CSC A;  3HWK A;  4CSC A;  2C6X A;  1IXE A;  3ENJ A;  5CSC A;  4YBO A;  1O7X A;  2P2W A;  1CTS A;  1CSH A;  2R9E A;  6CTS A;  2IBP A;  4JAD A;  2CTS A;  3TQG A;  2H12 A;  1NXE A;  2IFC A;  1VGP A;  2R26 A;  6CSC A;  4CTS A;  2CSC A;  1AL6 A;  1IOM A;  4TVM A;  1A59 A;  1OWC A;  1CSI A;  3O8J A;  4JAE A;  5CSC B;  4JAG A;  4JAF A;  1OWB A;  3CSC A;  1CSR A;  4XGH A;  5CTS A;  4G6B A; 
#chains in the Genus database with same CATH topology
 1VGM A;  1CSS A;  4E6Y A;  3MSU A;  1AJ8 A;  1AMZ A;  1NXG A;  1CSC A;  3HWK A;  4CSC A;  2C6X A;  1IXE A;  3ENJ A;  5CSC A;  4YBO A;  1O7X A;  2P2W A;  1CTS A;  1CSH A;  2R9E A;  6CTS A;  2IBP A;  4JAD A;  2CTS A;  3TQG A;  2H12 A;  1NXE A;  2IFC A;  1VGP A;  2R26 A;  6CSC A;  4CTS A;  2CSC A;  1AL6 A;  1IOM A;  4TVM A;  1A59 A;  1OWC A;  1CSI A;  3O8J A;  4JAE A;  5CSC B;  4JAG A;  4JAF A;  1OWB A;  3CSC A;  1CSR A;  4XGH A;  5CTS A;  4G6B A; 
#chains in the Genus database with same CATH homology
 1VGM A;  1CSS A;  4E6Y A;  3MSU A;  1AJ8 A;  1AMZ A;  1NXG A;  1CSC A;  3HWK A;  4CSC A;  2C6X A;  1IXE A;  3ENJ A;  5CSC A;  4YBO A;  1O7X A;  2P2W A;  1CTS A;  1CSH A;  2R9E A;  6CTS A;  2IBP A;  4JAD A;  2CTS A;  3TQG A;  2H12 A;  1NXE A;  2IFC A;  1VGP A;  2R26 A;  6CSC A;  4CTS A;  2CSC A;  1AL6 A;  1IOM A;  4TVM A;  1A59 A;  1OWC A;  1CSI A;  3O8J A;  4JAE A;  5CSC B;  4JAG A;  4JAF A;  1OWB A;  3CSC A;  1CSR A;  4XGH A;  5CTS A;  4G6B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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