4CSC | Genus

Total Genus 144

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	144
sequence length	433
structure length	429
Chain Sequence	ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGGGEPLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAAGADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYKIVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIAL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Oxo-acid-lyase
source organism	Gallus gallus
publication title	1.9-A structures of ternary complexes of citrate synthase with D- and L-malate: mechanistic implications. pubmed doi rcsb
molecule keywords	CITRATE SYNTHASE
total genus	144
structure length	429
sequence length	433
ec nomenclature	ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date	1990-05-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00285	Citrate_synt	Citrate synthase, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.230.10	Mainly Alpha	Orthogonal Bundle	Cytochrome p450-Terp; domain 2	Cytochrome P450-Terp, domain 2	4cscA02
1.10.580.10	Mainly Alpha	Orthogonal Bundle	Citrate Synthase; domain 1	Citrate Synthase, domain 1	4cscA01

4JAFA 4TVMA 1AL6A 2CSCA 1CSIA 2C6XA 3TQGA 3MSUA 1OWCA 4CSCA 1CSCA 5CSCA 4YBOA 3CSCA 1A59A 4JAGA 6CTSA 3HWKA 4CTSA 2R9EA 1AMZA 4XGHA 1O7XA 2H12A 5CSCB 5CTSA 3O8JA 1VGMA 4E6YA 1IOMA 2IBPA 4JAEA 3ENJA 1NXGA 1IXEA 1OWBA 1CSSA 1NXEA 1CSRA 2CTSA 6CSCA 4JADA 2R26A 1CTSA 2IFCA 2P2WA 1AJ8A 1CSHA 1VGPA 4G6BA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4JAF A;  4TVM A;  1AL6 A;  2CSC A;  1CSI A;  2C6X A;  3TQG A;  3MSU A;  1OWC A;  4CSC A;  1CSC A;  5CSC A;  4YBO A;  3CSC A;  1A59 A;  4JAG A;  6CTS A;  3HWK A;  4CTS A;  2R9E A;  1AMZ A;  4XGH A;  1O7X A;  2H12 A;  5CSC B;  5CTS A;  3O8J A;  1VGM A;  4E6Y A;  1IOM A;  2IBP A;  4JAE A;  3ENJ A;  1NXG A;  1IXE A;  1OWB A;  1CSS A;  1NXE A;  1CSR A;  2CTS A;  6CSC A;  4JAD A;  2R26 A;  1CTS A;  2IFC A;  2P2W A;  1AJ8 A;  1CSH A;  1VGP A;  4G6B A; 
#chains in the Genus database with same CATH topology
 4JAF A;  4TVM A;  1AL6 A;  2CSC A;  1CSI A;  2C6X A;  3TQG A;  3MSU A;  1OWC A;  4CSC A;  1CSC A;  5CSC A;  4YBO A;  3CSC A;  1A59 A;  4JAG A;  6CTS A;  3HWK A;  4CTS A;  2R9E A;  1AMZ A;  4XGH A;  1O7X A;  2H12 A;  5CSC B;  5CTS A;  3O8J A;  1VGM A;  4E6Y A;  1IOM A;  2IBP A;  4JAE A;  3ENJ A;  1NXG A;  1IXE A;  1OWB A;  1CSS A;  1NXE A;  1CSR A;  2CTS A;  6CSC A;  4JAD A;  2R26 A;  1CTS A;  2IFC A;  2P2W A;  1AJ8 A;  1CSH A;  1VGP A;  4G6B A; 
#chains in the Genus database with same CATH homology
 4JAF A;  4TVM A;  1AL6 A;  2CSC A;  1CSI A;  2C6X A;  3TQG A;  3MSU A;  1OWC A;  4CSC A;  1CSC A;  5CSC A;  4YBO A;  3CSC A;  1A59 A;  4JAG A;  6CTS A;  3HWK A;  4CTS A;  2R9E A;  1AMZ A;  4XGH A;  1O7X A;  2H12 A;  5CSC B;  5CTS A;  3O8J A;  1VGM A;  4E6Y A;  1IOM A;  2IBP A;  4JAE A;  3ENJ A;  1NXG A;  1IXE A;  1OWB A;  1CSS A;  1NXE A;  1CSR A;  2CTS A;  6CSC A;  4JAD A;  2R26 A;  1CTS A;  2IFC A;  2P2W A;  1AJ8 A;  1CSH A;  1VGP A;  4G6B A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4CSCA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations