4FXED

Crystal structure of the intact e. coli relbe toxin-antitoxin complex
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
78
structure length
71
Chain Sequence
YFLDFDERALKEWRKREQLKKKLVEVLESPRIEANKLRGMPDCYKIRSSGYRLVYQVIDEKVVVFVISVGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of the intact E. coli RelBE toxin-antitoxin complex provides the structural basis for conditional cooperativity.
pubmed doi rcsb
molecule keywords Antitoxin RelB
molecule tags Toxin/toxin inhibitor
source organism Escherichia coli
total genus 19
structure length 71
sequence length 78
chains with identical sequence E, F
ec nomenclature ec 3.1.-.-:
pdb deposition date 2012-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05016 ParE_toxin ParE toxin of type II toxin-antitoxin system, parDE
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2310.20 Alpha Beta 2-Layer Sandwich YaeB-like fold RelE-like 4fxeD00
3KXEA 4LS4A 2OTRA 2KC8A 3BPQB 2A6SA 4MCXB 4MMGA 2A6RA 4NRNA 3G5OB 4FXED 4PX8A 4Q2UB 2KHEA 5CZEB 3OEIC 4LTTA 5CEGB 4MMJA 5CZFC 4YY3Y 5IWHA 1WMIA 1Z8MA 4MCTB 2KC9A 5CW7B 4FXHA 2A6QE 5IXLA 4FXIA 4ML0B 4LSYA 4ML2A
chains in the Genus database with same CATH superfamily
3KXEA 4LS4A 2OTRA 2KC8A 3BPQB 2A6SA 4MCXB 4MMGA 2FHZB 1XQBA 2A6RA 4NRNA 3G5OB 4FXED 4PX8A 4Q2UB 2KHEA 5CZEB 3OEIC 4LTTA 4ML2A 5CEGB 4MMJA 5CZFC 4YY3Y 2PD0A 3VJ7A 2DJHA 5IWHA 1WMIA 1Z8MA 4MCTB 2KC9A 4FBDA 5CW7B 4FXHA 2A6QE 2A8KA 5IXLA 4FXIA 2DFXE 4ML0B 3AO9A 4LSYA 3HI2B
chains in the Genus database with same CATH topology
3KXEA 4LS4A 2OTRA 2KC8A 3BPQB 2A6SA 4MCXB 4MMGA 2A6RA 4NRNA 3G5OB 4FXED 4PX8A 4Q2UB 2KHEA 5CZEB 3OEIC 4LTTA 5CEGB 4MMJA 5CZFC 4YY3Y 5IWHA 1WMIA 1Z8MA 4MCTB 2KC9A 5CW7B 4FXHA 2A6QE 5IXLA 4FXIA 4ML0B 4LSYA 4ML2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KXE A;  4LS4 A;  2OTR A;  2KC8 A;  3BPQ B;  2A6S A;  4MCX B;  4MMG A;  2A6R A;  4NRN A;  3G5O B;  4FXE D;  4PX8 A;  4Q2U B;  2KHE A;  5CZE B;  3OEI C;  4LTT A;  5CEG B;  4MMJ A;  5CZF C;  4YY3 Y;  5IWH A;  1WMI A;  1Z8M A;  4MCT B;  2KC9 A;  5CW7 B;  4FXH A;  2A6Q E;  5IXL A;  4FXI A;  4ML0 B;  4LSY A;  4ML2 A; 
#chains in the Genus database with same CATH topology
 3KXE A;  4LS4 A;  2OTR A;  2KC8 A;  3BPQ B;  2A6S A;  4MCX B;  4MMG A;  2FHZ B;  1XQB A;  2A6R A;  4NRN A;  3G5O B;  4FXE D;  4PX8 A;  4Q2U B;  2KHE A;  5CZE B;  3OEI C;  4LTT A;  4ML2 A;  5CEG B;  4MMJ A;  5CZF C;  4YY3 Y;  2PD0 A;  3VJ7 A;  2DJH A;  5IWH A;  1WMI A;  1Z8M A;  4MCT B;  2KC9 A;  4FBD A;  5CW7 B;  4FXH A;  2A6Q E;  2A8K A;  5IXL A;  4FXI A;  2DFX E;  4ML0 B;  3AO9 A;  4LSY A;  3HI2 B; 
#chains in the Genus database with same CATH homology
 3KXE A;  4LS4 A;  2OTR A;  2KC8 A;  3BPQ B;  2A6S A;  4MCX B;  4MMG A;  2A6R A;  4NRN A;  3G5O B;  4FXE D;  4PX8 A;  4Q2U B;  2KHE A;  5CZE B;  3OEI C;  4LTT A;  5CEG B;  4MMJ A;  5CZF C;  4YY3 Y;  5IWH A;  1WMI A;  1Z8M A;  4MCT B;  2KC9 A;  5CW7 B;  4FXH A;  2A6Q E;  5IXL A;  4FXI A;  4ML0 B;  4LSY A;  4ML2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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