4FXHA

Crystal structure of the isolated e. coli rele toxin, p212121 form
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
94
structure length
87
Chain Sequence
AYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDYKIKRLVYQVIDEKVVVFVISVGKAERSEVYSEAVKRIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords mRNA interferase RelE
publication title The crystal structure of the intact E. coli RelBE toxin-antitoxin complex provides the structural basis for conditional cooperativity.
pubmed doi rcsb
source organism Escherichia coli
total genus 26
structure length 87
sequence length 94
chains with identical sequence B
ec nomenclature ec 3.1.-.-:
pdb deposition date 2012-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05016 ParE_toxin ParE toxin of type II toxin-antitoxin system, parDE
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2310.20 Alpha Beta 2-Layer Sandwich YaeB-like fold RelE-like 4fxhA00
2KC8A 2KHEA 4FXHA 3G5OB 3BPQB 2A6RA 4PX8A 3KXEA 4NRNA 1WMIA 4MCTB 4MMJA 4ML2A 5IXLA 5CW7B 5IWHA 2A6QE 2OTRA 2A6SA 4MCXB 4LTTA 4LS4A 1Z8MA 4ML0B 5CZFC 4LSYA 4YY3Y 4MMGA 4Q2UB 5CEGB 5CZEB 3OEIC 4FXED 2KC9A 4FXIA
chains in the Genus database with same CATH superfamily
2KC8A 2KHEA 4FXHA 3G5OB 3BPQB 2A6RA 3HI2B 4PX8A 3KXEA 4NRNA 1XQBA 1WMIA 4MCTB 4MMJA 4ML2A 5IXLA 5CW7B 5IWHA 2PD0A 2A6QE 2OTRA 2A6SA 4MCXB 4LTTA 3VJ7A 4LS4A 1Z8MA 4ML0B 2A8KA 2FHZB 5CZFC 4LSYA 4YY3Y 4MMGA 4FBDA 4Q2UB 5CEGB 5CZEB 2DJHA 2DFXE 3AO9A 3OEIC 4FXED 2KC9A 4FXIA
chains in the Genus database with same CATH topology
2KC8A 2KHEA 4FXHA 3G5OB 3BPQB 2A6RA 4PX8A 3KXEA 4NRNA 1WMIA 4MCTB 4MMJA 4ML2A 5IXLA 5CW7B 5IWHA 2A6QE 2OTRA 2A6SA 4MCXB 4LTTA 4LS4A 1Z8MA 4ML0B 5CZFC 4LSYA 4YY3Y 4MMGA 4Q2UB 5CEGB 5CZEB 3OEIC 4FXED 2KC9A 4FXIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KC8 A;  2KHE A;  4FXH A;  3G5O B;  3BPQ B;  2A6R A;  4PX8 A;  3KXE A;  4NRN A;  1WMI A;  4MCT B;  4MMJ A;  4ML2 A;  5IXL A;  5CW7 B;  5IWH A;  2A6Q E;  2OTR A;  2A6S A;  4MCX B;  4LTT A;  4LS4 A;  1Z8M A;  4ML0 B;  5CZF C;  4LSY A;  4YY3 Y;  4MMG A;  4Q2U B;  5CEG B;  5CZE B;  3OEI C;  4FXE D;  2KC9 A;  4FXI A; 
#chains in the Genus database with same CATH topology
 2KC8 A;  2KHE A;  4FXH A;  3G5O B;  3BPQ B;  2A6R A;  3HI2 B;  4PX8 A;  3KXE A;  4NRN A;  1XQB A;  1WMI A;  4MCT B;  4MMJ A;  4ML2 A;  5IXL A;  5CW7 B;  5IWH A;  2PD0 A;  2A6Q E;  2OTR A;  2A6S A;  4MCX B;  4LTT A;  3VJ7 A;  4LS4 A;  1Z8M A;  4ML0 B;  2A8K A;  2FHZ B;  5CZF C;  4LSY A;  4YY3 Y;  4MMG A;  4FBD A;  4Q2U B;  5CEG B;  5CZE B;  2DJH A;  2DFX E;  3AO9 A;  3OEI C;  4FXE D;  2KC9 A;  4FXI A; 
#chains in the Genus database with same CATH homology
 2KC8 A;  2KHE A;  4FXH A;  3G5O B;  3BPQ B;  2A6R A;  4PX8 A;  3KXE A;  4NRN A;  1WMI A;  4MCT B;  4MMJ A;  4ML2 A;  5IXL A;  5CW7 B;  5IWH A;  2A6Q E;  2OTR A;  2A6S A;  4MCX B;  4LTT A;  4LS4 A;  1Z8M A;  4ML0 B;  5CZF C;  4LSY A;  4YY3 Y;  4MMG A;  4Q2U B;  5CEG B;  5CZE B;  3OEI C;  4FXE D;  2KC9 A;  4FXI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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