4FXED

Crystal structure of the intact e. coli relbe toxin-antitoxin complex
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
78
structure length
71
Chain Sequence
YFLDFDERALKEWRKREQLKKKLVEVLESPRIEANKLRGMPDCYKIRSSGYRLVYQVIDEKVVVFVISVGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin/toxin inhibitor
molecule keywords Antitoxin RelB
publication title The crystal structure of the intact E. coli RelBE toxin-antitoxin complex provides the structural basis for conditional cooperativity.
pubmed doi rcsb
source organism Escherichia coli
total genus 19
structure length 71
sequence length 78
chains with identical sequence E, F
ec nomenclature ec 3.1.-.-:
pdb deposition date 2012-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05016 ParE_toxin ParE toxin of type II toxin-antitoxin system, parDE
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2310.20 Alpha Beta 2-Layer Sandwich YaeB-like fold RelE-like 4fxeD00
4FXED 2KC9A 4ML0B 1Z8MA 5CW7B 2KHEA 4FXHA 4FXIA 4LS4A 4ML2A 4MCXB 2A6SA 2A6QE 4YY3Y 3BPQB 4NRNA 5CZFC 4LSYA 4MCTB 5CZEB 2OTRA 3KXEA 2KC8A 4MMJA 1WMIA 4Q2UB 3OEIC 2A6RA 3G5OB 4LTTA 4PX8A 5IXLA 5CEGB 4MMGA 5IWHA
chains in the Genus database with same CATH superfamily
4FXED 2KC9A 4ML0B 1Z8MA 5CW7B 2KHEA 2FHZB 2PD0A 2DFXE 3HI2B 4FXHA 4FXIA 4LS4A 4ML2A 4MCXB 2A6SA 4FBDA 1XQBA 2A6QE 4YY3Y 3BPQB 2A8KA 4NRNA 5CZFC 4LSYA 4MCTB 5CZEB 2OTRA 3KXEA 2KC8A 4MMJA 1WMIA 3AO9A 4Q2UB 3OEIC 2A6RA 3G5OB 4LTTA 4PX8A 5IXLA 3VJ7A 2DJHA 5CEGB 4MMGA 5IWHA
chains in the Genus database with same CATH topology
4FXED 2KC9A 4ML0B 1Z8MA 5CW7B 2KHEA 4FXHA 4FXIA 4LS4A 4ML2A 4MCXB 2A6SA 2A6QE 4YY3Y 3BPQB 4NRNA 5CZFC 4LSYA 4MCTB 5CZEB 2OTRA 3KXEA 2KC8A 4MMJA 1WMIA 4Q2UB 3OEIC 2A6RA 3G5OB 4LTTA 4PX8A 5IXLA 5CEGB 4MMGA 5IWHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FXE D;  2KC9 A;  4ML0 B;  1Z8M A;  5CW7 B;  2KHE A;  4FXH A;  4FXI A;  4LS4 A;  4ML2 A;  4MCX B;  2A6S A;  2A6Q E;  4YY3 Y;  3BPQ B;  4NRN A;  5CZF C;  4LSY A;  4MCT B;  5CZE B;  2OTR A;  3KXE A;  2KC8 A;  4MMJ A;  1WMI A;  4Q2U B;  3OEI C;  2A6R A;  3G5O B;  4LTT A;  4PX8 A;  5IXL A;  5CEG B;  4MMG A;  5IWH A; 
#chains in the Genus database with same CATH topology
 4FXE D;  2KC9 A;  4ML0 B;  1Z8M A;  5CW7 B;  2KHE A;  2FHZ B;  2PD0 A;  2DFX E;  3HI2 B;  4FXH A;  4FXI A;  4LS4 A;  4ML2 A;  4MCX B;  2A6S A;  4FBD A;  1XQB A;  2A6Q E;  4YY3 Y;  3BPQ B;  2A8K A;  4NRN A;  5CZF C;  4LSY A;  4MCT B;  5CZE B;  2OTR A;  3KXE A;  2KC8 A;  4MMJ A;  1WMI A;  3AO9 A;  4Q2U B;  3OEI C;  2A6R A;  3G5O B;  4LTT A;  4PX8 A;  5IXL A;  3VJ7 A;  2DJH A;  5CEG B;  4MMG A;  5IWH A; 
#chains in the Genus database with same CATH homology
 4FXE D;  2KC9 A;  4ML0 B;  1Z8M A;  5CW7 B;  2KHE A;  4FXH A;  4FXI A;  4LS4 A;  4ML2 A;  4MCX B;  2A6S A;  2A6Q E;  4YY3 Y;  3BPQ B;  4NRN A;  5CZF C;  4LSY A;  4MCT B;  5CZE B;  2OTR A;  3KXE A;  2KC8 A;  4MMJ A;  1WMI A;  4Q2U B;  3OEI C;  2A6R A;  3G5O B;  4LTT A;  4PX8 A;  5IXL A;  5CEG B;  4MMG A;  5IWH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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