4FXHA

Crystal structure of the isolated e. coli rele toxin, p212121 form
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
94
structure length
87
Chain Sequence
AYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDYKIKRLVYQVIDEKVVVFVISVGKAERSEVYSEAVKRIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of the intact E. coli RelBE toxin-antitoxin complex provides the structural basis for conditional cooperativity.
pubmed doi rcsb
molecule keywords mRNA interferase RelE
molecule tags Toxin
source organism Escherichia coli
total genus 26
structure length 87
sequence length 94
chains with identical sequence B
ec nomenclature ec 3.1.-.-:
pdb deposition date 2012-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05016 ParE_toxin ParE toxin of type II toxin-antitoxin system, parDE
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2310.20 Alpha Beta 2-Layer Sandwich YaeB-like fold RelE-like 4fxhA00
5CZFC 4ML0B 2A6QE 1Z8MA 4PX8A 2KC9A 4FXED 2KHEA 5CW7B 4MMJA 4FXIA 4Q2UB 5IWHA 4YY3Y 3KXEA 4MCXB 4LS4A 4ML2A 5IXLA 4LSYA 1WMIA 2KC8A 3G5OB 2A6RA 4MCTB 4NRNA 5CEGB 5CZEB 4LTTA 2OTRA 3OEIC 4MMGA 3BPQB 4FXHA 2A6SA
chains in the Genus database with same CATH superfamily
2DJHA 4ML0B 5CZFC 3VJ7A 2A6QE 1Z8MA 3HI2B 2KC9A 4PX8A 4FXED 2KHEA 5CW7B 2FHZB 4MMJA 4FXIA 4Q2UB 5IWHA 4YY3Y 3KXEA 4MCXB 2DFXE 4LS4A 2PD0A 4ML2A 5IXLA 4LSYA 1WMIA 2KC8A 3G5OB 2A6RA 4MCTB 4NRNA 5CEGB 5CZEB 4LTTA 2A8KA 2OTRA 3OEIC 3AO9A 1XQBA 4MMGA 3BPQB 4FXHA 2A6SA 4FBDA
chains in the Genus database with same CATH topology
5CZFC 4ML0B 2A6QE 1Z8MA 4PX8A 2KC9A 4FXED 2KHEA 5CW7B 4MMJA 4FXIA 4Q2UB 5IWHA 4YY3Y 3KXEA 4MCXB 4LS4A 4ML2A 5IXLA 4LSYA 1WMIA 2KC8A 3G5OB 2A6RA 4MCTB 4NRNA 5CEGB 5CZEB 4LTTA 2OTRA 3OEIC 4MMGA 3BPQB 4FXHA 2A6SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CZF C;  4ML0 B;  2A6Q E;  1Z8M A;  4PX8 A;  2KC9 A;  4FXE D;  2KHE A;  5CW7 B;  4MMJ A;  4FXI A;  4Q2U B;  5IWH A;  4YY3 Y;  3KXE A;  4MCX B;  4LS4 A;  4ML2 A;  5IXL A;  4LSY A;  1WMI A;  2KC8 A;  3G5O B;  2A6R A;  4MCT B;  4NRN A;  5CEG B;  5CZE B;  4LTT A;  2OTR A;  3OEI C;  4MMG A;  3BPQ B;  4FXH A;  2A6S A; 
#chains in the Genus database with same CATH topology
 2DJH A;  4ML0 B;  5CZF C;  3VJ7 A;  2A6Q E;  1Z8M A;  3HI2 B;  2KC9 A;  4PX8 A;  4FXE D;  2KHE A;  5CW7 B;  2FHZ B;  4MMJ A;  4FXI A;  4Q2U B;  5IWH A;  4YY3 Y;  3KXE A;  4MCX B;  2DFX E;  4LS4 A;  2PD0 A;  4ML2 A;  5IXL A;  4LSY A;  1WMI A;  2KC8 A;  3G5O B;  2A6R A;  4MCT B;  4NRN A;  5CEG B;  5CZE B;  4LTT A;  2A8K A;  2OTR A;  3OEI C;  3AO9 A;  1XQB A;  4MMG A;  3BPQ B;  4FXH A;  2A6S A;  4FBD A; 
#chains in the Genus database with same CATH homology
 5CZF C;  4ML0 B;  2A6Q E;  1Z8M A;  4PX8 A;  2KC9 A;  4FXE D;  2KHE A;  5CW7 B;  4MMJ A;  4FXI A;  4Q2U B;  5IWH A;  4YY3 Y;  3KXE A;  4MCX B;  4LS4 A;  4ML2 A;  5IXL A;  4LSY A;  1WMI A;  2KC8 A;  3G5O B;  2A6R A;  4MCT B;  4NRN A;  5CEG B;  5CZE B;  4LTT A;  2OTR A;  3OEI C;  4MMG A;  3BPQ B;  4FXH A;  2A6S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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