4HW5A

Crystal structure of the human c3a anaphylatoxin
Total Genus 24
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
77
structure length
77
Chain Sequence
SVQLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLAR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Complement C3
total genus 24
structure length 77
sequence length 77
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01821 ANATO Anaphylotoxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.91.20 Mainly Alpha Up-down Bundle Influenza Virus Matrix Protein; Chain A, domain 1 Anaphylotoxins (complement system) 4hw5A00
3HQBA 4UU9C 4P3AA 1C5AA 4HW5A 2B39A 4FXKB 4P3BA 1KJSA 5JPNB 2A73B 4HWJA 4WB3A 4I6OA 5B4PB 4P39A 3KLSA 1CFAA 3HQAA 4WB2A 3CU7A
chains in the Genus database with same CATH superfamily
3HQBA 4UU9C 4PUSA 4P3AA 1C5AA 1AA7A 4HW5A 5CQEA 2B39A 4FXKB 4P3BA 1KJSA 4ITVA 5JPNB 3VDXA 2A73B 4HWJA 4WB3A 4I6OA 4D9JA 1EA3A 2Z16A 5B4PB 4P39A 3KLSA 5JPMB 4IQ4A 1CFAA 3HQAA 4WB2A 3CU7A 3MD2A 4FXGB
chains in the Genus database with same CATH topology
3HQBA 4UU9C 4P3AA 1C5AA 4HW5A 2B39A 4FXKB 4P3BA 1KJSA 5JPNB 2A73B 4HWJA 4WB3A 4I6OA 5B4PB 4P39A 3KLSA 1CFAA 3HQAA 4WB2A 3CU7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HQB A;  4UU9 C;  4P3A A;  1C5A A;  4HW5 A;  2B39 A;  4FXK B;  4P3B A;  1KJS A;  5JPN B;  2A73 B;  4HWJ A;  4WB3 A;  4I6O A;  5B4P B;  4P39 A;  3KLS A;  1CFA A;  3HQA A;  4WB2 A;  3CU7 A; 
#chains in the Genus database with same CATH topology
 3HQB A;  4UU9 C;  4PUS A;  4P3A A;  1C5A A;  1AA7 A;  4HW5 A;  5CQE A;  2B39 A;  4FXK B;  4P3B A;  1KJS A;  4ITV A;  5JPN B;  3VDX A;  2A73 B;  4HWJ A;  4WB3 A;  4I6O A;  4D9J A;  1EA3 A;  2Z16 A;  5B4P B;  4P39 A;  3KLS A;  5JPM B;  4IQ4 A;  1CFA A;  3HQA A;  4WB2 A;  3CU7 A;  3MD2 A;  4FXG B; 
#chains in the Genus database with same CATH homology
 3HQB A;  4UU9 C;  4P3A A;  1C5A A;  4HW5 A;  2B39 A;  4FXK B;  4P3B A;  1KJS A;  5JPN B;  2A73 B;  4HWJ A;  4WB3 A;  4I6O A;  5B4P B;  4P39 A;  3KLS A;  1CFA A;  3HQA A;  4WB2 A;  3CU7 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...