4I6OA

Crystal structure of chemically synthesized human anaphylatoxin c3a
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
68
structure length
68
Chain Sequence
DKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
molecule keywords Complement C3
publication title Efficient chemical synthesis of human complement protein C3a.
pubmed doi rcsb
total genus 22
structure length 68
sequence length 68
ec nomenclature
pdb deposition date 2012-11-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01821 ANATO Anaphylotoxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.91.20 Mainly Alpha Up-down Bundle Influenza Virus Matrix Protein; Chain A, domain 1 Anaphylotoxins (complement system) 4i6oA00
4UU9C 1KJSA 4P3BA 4WB3A 4HWJA 4I6OA 2A73B 4HW5A 4P39A 1C5AA 4WB2A 4FXKB 3KLSA 3HQAA 3HQBA 1CFAA 4P3AA 5JPNB 3CU7A 5B4PB 2B39A
chains in the Genus database with same CATH superfamily
4UU9C 4PUSA 1KJSA 4P3BA 1AA7A 4WB3A 4HWJA 5CQEA 4I6OA 1EA3A 3VDXA 2A73B 3MD2A 5JPMB 4HW5A 4P39A 4ITVA 1C5AA 4FXGB 4FXKB 4WB2A 4IQ4A 3KLSA 3HQAA 3HQBA 1CFAA 2Z16A 4P3AA 4D9JA 5JPNB 3CU7A 5B4PB 2B39A
chains in the Genus database with same CATH topology
4UU9C 1KJSA 4P3BA 4WB3A 4HWJA 4I6OA 2A73B 4HW5A 4P39A 1C5AA 4WB2A 4FXKB 3KLSA 3HQAA 3HQBA 1CFAA 4P3AA 5JPNB 3CU7A 5B4PB 2B39A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UU9 C;  1KJS A;  4P3B A;  4WB3 A;  4HWJ A;  4I6O A;  2A73 B;  4HW5 A;  4P39 A;  1C5A A;  4WB2 A;  4FXK B;  3KLS A;  3HQA A;  3HQB A;  1CFA A;  4P3A A;  5JPN B;  3CU7 A;  5B4P B;  2B39 A; 
#chains in the Genus database with same CATH topology
 4UU9 C;  4PUS A;  1KJS A;  4P3B A;  1AA7 A;  4WB3 A;  4HWJ A;  5CQE A;  4I6O A;  1EA3 A;  3VDX A;  2A73 B;  3MD2 A;  5JPM B;  4HW5 A;  4P39 A;  4ITV A;  1C5A A;  4FXG B;  4FXK B;  4WB2 A;  4IQ4 A;  3KLS A;  3HQA A;  3HQB A;  1CFA A;  2Z16 A;  4P3A A;  4D9J A;  5JPN B;  3CU7 A;  5B4P B;  2B39 A; 
#chains in the Genus database with same CATH homology
 4UU9 C;  1KJS A;  4P3B A;  4WB3 A;  4HWJ A;  4I6O A;  2A73 B;  4HW5 A;  4P39 A;  1C5A A;  4WB2 A;  4FXK B;  3KLS A;  3HQA A;  3HQB A;  1CFA A;  4P3A A;  5JPN B;  3CU7 A;  5B4P B;  2B39 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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