4HWJA

Crystal structure of the human c3a desarg anaphylatoxin
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
75
structure length
75
Chain Sequence
VQLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg.
pubmed doi rcsb
molecule keywords Complement C3
molecule tags Immune system
source organism Homo sapiens
total genus 26
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2012-11-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01821 ANATO Anaphylotoxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.91.20 Mainly Alpha Up-down Bundle Influenza Virus Matrix Protein; Chain A, domain 1 Anaphylotoxins (complement system) 4hwjA00
4I6OA 4WB2A 4HWJA 4WB3A 3KLSA 3HQBA 4P39A 3HQAA 5B4PB 1C5AA 4FXKB 4UU9C 4HW5A 4P3BA 2A73B 3CU7A 5JPNB 1KJSA 2B39A 4P3AA 1CFAA
chains in the Genus database with same CATH superfamily
4I6OA 4WB2A 3VDXA 4HWJA 3MD2A 4WB3A 3KLSA 4PUSA 3HQBA 4P39A 5CQEA 3HQAA 1EA3A 5B4PB 1C5AA 4IQ4A 5JPMB 4FXGB 4FXKB 4UU9C 4D9JA 4HW5A 2Z16A 4P3BA 4ITVA 2A73B 3CU7A 1AA7A 5JPNB 1KJSA 2B39A 4P3AA 1CFAA
chains in the Genus database with same CATH topology
4I6OA 4WB2A 4HWJA 4WB3A 3KLSA 3HQBA 4P39A 3HQAA 5B4PB 1C5AA 4FXKB 4UU9C 4HW5A 4P3BA 2A73B 3CU7A 5JPNB 1KJSA 2B39A 4P3AA 1CFAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I6O A;  4WB2 A;  4HWJ A;  4WB3 A;  3KLS A;  3HQB A;  4P39 A;  3HQA A;  5B4P B;  1C5A A;  4FXK B;  4UU9 C;  4HW5 A;  4P3B A;  2A73 B;  3CU7 A;  5JPN B;  1KJS A;  2B39 A;  4P3A A;  1CFA A; 
#chains in the Genus database with same CATH topology
 4I6O A;  4WB2 A;  3VDX A;  4HWJ A;  3MD2 A;  4WB3 A;  3KLS A;  4PUS A;  3HQB A;  4P39 A;  5CQE A;  3HQA A;  1EA3 A;  5B4P B;  1C5A A;  4IQ4 A;  5JPM B;  4FXG B;  4FXK B;  4UU9 C;  4D9J A;  4HW5 A;  2Z16 A;  4P3B A;  4ITV A;  2A73 B;  3CU7 A;  1AA7 A;  5JPN B;  1KJS A;  2B39 A;  4P3A A;  1CFA A; 
#chains in the Genus database with same CATH homology
 4I6O A;  4WB2 A;  4HWJ A;  4WB3 A;  3KLS A;  3HQB A;  4P39 A;  3HQA A;  5B4P B;  1C5A A;  4FXK B;  4UU9 C;  4HW5 A;  4P3B A;  2A73 B;  3CU7 A;  5JPN B;  1KJS A;  2B39 A;  4P3A A;  1CFA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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