4K3L | Genus

Total Genus 88

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	88
sequence length	365
structure length	353
Chain Sequence	MKFTVEREHLLKPLQQVSPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMR

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Escherichia coli
publication title	Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp pubmed doi rcsb
molecule keywords	DNA polymerase III subunit beta
total genus	88
structure length	353
sequence length	365
chains with identical sequence	B
ec nomenclature	ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date	2013-04-10

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00712	DNA_pol3_beta	DNA polymerase III beta subunit, N-terminal domain
A	PF02767	DNA_pol3_beta_2	DNA polymerase III beta subunit, central domain
A	PF02768	DNA_pol3_beta_3	DNA polymerase III beta subunit, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4k3lA02
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4k3lA03
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4k3lA01

4N96A 4K74A 3PGEB 4S3IA 3T0PA 3P16A 1VPKA 4TR6A 2XURA 4OVGA 4OVHA 4K3KA 5FVEA 4K3RA 4N97A 3Q4KA 1JQJA 4MJQA 4N99A 4N95A 4PNWA 4RKIA 3PWEA 3F1VA 4N94A 2AVTA 4K3LA 3D1FA 4N9AA 4K3OA 3L0WA 4K3QA 3D1EA 3L0XA 5AGVA 4TR8A 4OVFA 1JQLA 4K3PA 4MJRA 4TSZA 3Q4JA 4TRTA 1OK7A 4TR7A 4N98A 5AGUA 4PNUA 4MJPA 2AWAA 4K3MA 3L10A 3QSBB 3QSBA 4K3SA 1MMIA 5AH4A 3Q4LA 1UNNA 3D1GA 3RB9A 2POLA 4PNVA 3BEPA 5FRQA 5AH2A
chains in the Genus database with same CATH superfamily

4N96A 4K74A 3PGEB 4S3IA 3T0PA 3PGEA 3P16A 1VPKA 4TR6A 2XURA 4OVGA 4OVHA 4K3KA 5FVEA 4K3RA 4N97A 3Q4KA 1JQJA 4MJQA 4N99A 4N95A 4PNWA 4RKIA 3PWEA 3F1VA 4N94A 2AVTA 4K3LA 3L0XB 3D1FA 4N9AA 3L0WB 4K3OA 3L0WA 4K3QA 3D1EA 3L0XA 5AGVA 4TR8A 4OVFA 1JQLA 4K3PA 4MJRA 4TSZA 3Q4JA 4TRTA 1OK7A 3L10B 4N98A 4TR7A 5AGUA 4PNUA 4MJPA 2AWAA 4K3MA 3L10A 3QSBB 3QSBA 4K3SA 1MMIA 5AH4A 3Q4LA 1UNNA 3D1GA 3RB9A 2POLA 4PNVA 3BEPA 5FRQA 5AH2A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4N96 A;  4K74 A;  3PGE B;  4S3I A;  3T0P A;  3P16 A;  1VPK A;  4TR6 A;  2XUR A;  4OVG A;  4OVH A;  4K3K A;  5FVE A;  4K3R A;  4N97 A;  3Q4K A;  1JQJ A;  4MJQ A;  4N99 A;  4N95 A;  4PNW A;  4RKI A;  3PWE A;  3F1V A;  4N94 A;  2AVT A;  4K3L A;  3D1F A;  4N9A A;  4K3O A;  3L0W A;  4K3Q A;  3D1E A;  3L0X A;  5AGV A;  4TR8 A;  4OVF A;  1JQL A;  4K3P A;  4MJR A;  4TSZ A;  3Q4J A;  4TRT A;  1OK7 A;  4TR7 A;  4N98 A;  5AGU A;  4PNU A;  4MJP A;  2AWA A;  4K3M A;  3L10 A;  3QSB B;  3QSB A;  4K3S A;  1MMI A;  5AH4 A;  3Q4L A;  1UNN A;  3D1G A;  3RB9 A;  2POL A;  4PNV A;  3BEP A;  5FRQ A;  5AH2 A; 
#chains in the Genus database with same CATH topology
 4N96 A;  4K74 A;  3PGE B;  4S3I A;  3T0P A;  3PGE A;  3P16 A;  1VPK A;  4TR6 A;  2XUR A;  4OVG A;  4OVH A;  4K3K A;  5FVE A;  4K3R A;  4N97 A;  3Q4K A;  1JQJ A;  4MJQ A;  4N99 A;  4N95 A;  4PNW A;  4RKI A;  3PWE A;  3F1V A;  4N94 A;  2AVT A;  4K3L A;  3L0X B;  3D1F A;  4N9A A;  3L0W B;  4K3O A;  3L0W A;  4K3Q A;  3D1E A;  3L0X A;  5AGV A;  4TR8 A;  4OVF A;  1JQL A;  4K3P A;  4MJR A;  4TSZ A;  3Q4J A;  4TRT A;  1OK7 A;  3L10 B;  4N98 A;  4TR7 A;  5AGU A;  4PNU A;  4MJP A;  2AWA A;  4K3M A;  3L10 A;  3QSB B;  3QSB A;  4K3S A;  1MMI A;  5AH4 A;  3Q4L A;  1UNN A;  3D1G A;  3RB9 A;  2POL A;  4PNV A;  3BEP A;  5FRQ A;  5AH2 A; 
#chains in the Genus database with same CATH homology
 4N96 A;  4K74 A;  3PGE B;  4S3I A;  3T0P A;  3P16 A;  1VPK A;  4TR6 A;  2XUR A;  4OVG A;  4OVH A;  4K3K A;  5FVE A;  4K3R A;  4N97 A;  3Q4K A;  1JQJ A;  4MJQ A;  4N99 A;  4N95 A;  4PNW A;  4RKI A;  3PWE A;  3F1V A;  4N94 A;  2AVT A;  4K3L A;  3D1F A;  4N9A A;  4K3O A;  3L0W A;  4K3Q A;  3D1E A;  3L0X A;  5AGV A;  4TR8 A;  4OVF A;  1JQL A;  4K3P A;  4MJR A;  4TSZ A;  3Q4J A;  4TRT A;  1OK7 A;  4TR7 A;  4N98 A;  5AGU A;  4PNU A;  4MJP A;  2AWA A;  4K3M A;  3L10 A;  3QSB B;  3QSB A;  4K3S A;  1MMI A;  5AH4 A;  3Q4L A;  1UNN A;  3D1G A;  3RB9 A;  2POL A;  4PNV A;  3BEP A;  5FRQ A;  5AH2 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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4K3LA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations