4K3R | Genus

Total Genus 86

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	86
sequence length	365
structure length	358
Chain Sequence	MKFTVEREHLLKPLQQVSGLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 358 atoms

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358 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Escherichia coli
publication title	Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp pubmed doi rcsb
molecule keywords	DNA polymerase III subunit beta
total genus	86
structure length	358
sequence length	365
chains with identical sequence	B
ec nomenclature	ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date	2013-04-11

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00712	DNA_pol3_beta	DNA polymerase III beta subunit, N-terminal domain
A	PF02767	DNA_pol3_beta_2	DNA polymerase III beta subunit, central domain
A	PF02768	DNA_pol3_beta_3	DNA polymerase III beta subunit, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4k3rA02
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4k3rA03
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4k3rA01

4K3RA 4K3MA 4RKIA 4K3OA 4MJPA 3L10A 1UNNA 3Q4KA 4OVGA 4K3QA 4TSZA 3L0XA 4TRTA 2XURA 2POLA 3D1FA 1JQLA 3QSBB 4TR6A 5AGVA 4N9AA 3L0WA 3F1VA 4N98A 2AVTA 3RB9A 4PNUA 4K74A 5AGUA 4K3PA 1VPKA 4K3KA 5FRQA 1MMIA 4PNWA 4TR7A 4PNVA 4MJQA 5FVEA 4N96A 4MJRA 3PWEA 4N94A 3Q4LA 4N99A 4TR8A 4K3SA 3Q4JA 4N95A 3PGEB 4OVHA 4N97A 5AH4A 3T0PA 4S3IA 3BEPA 4OVFA 5AH2A 4K3LA 3D1GA 1OK7A 3D1EA 1JQJA 2AWAA 3QSBA 3P16A
chains in the Genus database with same CATH superfamily

4K3RA 4K3MA 4RKIA 4K3OA 4MJPA 3L10A 1UNNA 3Q4KA 4OVGA 4K3QA 4TSZA 3L0XA 4TRTA 2XURA 3L0WB 2POLA 3D1FA 1JQLA 3QSBB 4TR6A 5AGVA 4N9AA 3L0WA 3F1VA 4N98A 2AVTA 3RB9A 3L10B 4PNUA 3L0XB 4K74A 5AGUA 4K3PA 1VPKA 4K3KA 5FRQA 1MMIA 4PNWA 4TR7A 4PNVA 4MJQA 5FVEA 3PGEA 4N96A 4MJRA 3PWEA 4N94A 3Q4LA 4N99A 4TR8A 4K3SA 3Q4JA 4N95A 3PGEB 4OVHA 4N97A 5AH4A 3T0PA 4S3IA 3BEPA 4OVFA 5AH2A 4K3LA 3D1GA 1OK7A 3D1EA 1JQJA 2AWAA 3QSBA 3P16A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4K3R A;  4K3M A;  4RKI A;  4K3O A;  4MJP A;  3L10 A;  1UNN A;  3Q4K A;  4OVG A;  4K3Q A;  4TSZ A;  3L0X A;  4TRT A;  2XUR A;  2POL A;  3D1F A;  1JQL A;  3QSB B;  4TR6 A;  5AGV A;  4N9A A;  3L0W A;  3F1V A;  4N98 A;  2AVT A;  3RB9 A;  4PNU A;  4K74 A;  5AGU A;  4K3P A;  1VPK A;  4K3K A;  5FRQ A;  1MMI A;  4PNW A;  4TR7 A;  4PNV A;  4MJQ A;  5FVE A;  4N96 A;  4MJR A;  3PWE A;  4N94 A;  3Q4L A;  4N99 A;  4TR8 A;  4K3S A;  3Q4J A;  4N95 A;  3PGE B;  4OVH A;  4N97 A;  5AH4 A;  3T0P A;  4S3I A;  3BEP A;  4OVF A;  5AH2 A;  4K3L A;  3D1G A;  1OK7 A;  3D1E A;  1JQJ A;  2AWA A;  3QSB A;  3P16 A; 
#chains in the Genus database with same CATH topology
 4K3R A;  4K3M A;  4RKI A;  4K3O A;  4MJP A;  3L10 A;  1UNN A;  3Q4K A;  4OVG A;  4K3Q A;  4TSZ A;  3L0X A;  4TRT A;  2XUR A;  3L0W B;  2POL A;  3D1F A;  1JQL A;  3QSB B;  4TR6 A;  5AGV A;  4N9A A;  3L0W A;  3F1V A;  4N98 A;  2AVT A;  3RB9 A;  3L10 B;  4PNU A;  3L0X B;  4K74 A;  5AGU A;  4K3P A;  1VPK A;  4K3K A;  5FRQ A;  1MMI A;  4PNW A;  4TR7 A;  4PNV A;  4MJQ A;  5FVE A;  3PGE A;  4N96 A;  4MJR A;  3PWE A;  4N94 A;  3Q4L A;  4N99 A;  4TR8 A;  4K3S A;  3Q4J A;  4N95 A;  3PGE B;  4OVH A;  4N97 A;  5AH4 A;  3T0P A;  4S3I A;  3BEP A;  4OVF A;  5AH2 A;  4K3L A;  3D1G A;  1OK7 A;  3D1E A;  1JQJ A;  2AWA A;  3QSB A;  3P16 A; 
#chains in the Genus database with same CATH homology
 4K3R A;  4K3M A;  4RKI A;  4K3O A;  4MJP A;  3L10 A;  1UNN A;  3Q4K A;  4OVG A;  4K3Q A;  4TSZ A;  3L0X A;  4TRT A;  2XUR A;  2POL A;  3D1F A;  1JQL A;  3QSB B;  4TR6 A;  5AGV A;  4N9A A;  3L0W A;  3F1V A;  4N98 A;  2AVT A;  3RB9 A;  4PNU A;  4K74 A;  5AGU A;  4K3P A;  1VPK A;  4K3K A;  5FRQ A;  1MMI A;  4PNW A;  4TR7 A;  4PNV A;  4MJQ A;  5FVE A;  4N96 A;  4MJR A;  3PWE A;  4N94 A;  3Q4L A;  4N99 A;  4TR8 A;  4K3S A;  3Q4J A;  4N95 A;  3PGE B;  4OVH A;  4N97 A;  5AH4 A;  3T0P A;  4S3I A;  3BEP A;  4OVF A;  5AH2 A;  4K3L A;  3D1G A;  1OK7 A;  3D1E A;  1JQJ A;  2AWA A;  3QSB A;  3P16 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4K3RA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations