4MCX | Genus

Total Genus 22

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	22
sequence length	93
structure length	93
Chain Sequence	SHMMIKSFKHKGLKLLFEKGVTSGVPAQDVDRINDRLQAIDTATEIGELNRQIYKLHPLKGDREGYWSITVRANWRITFQFINGDAYILNYED

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 93 atoms

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93 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Structure of the Proteus vulgaris HigB-(HigA)2-HigB Toxin-Antitoxin Complex. pubmed doi rcsb
molecule keywords	Antidote protein
molecule tags	Toxin
source organism	Proteus vulgaris
total genus	22
structure length	93
sequence length	93
chains with identical sequence	D, F
ec nomenclature
pdb deposition date	2013-08-21

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
B	PF05015	HigB-like_toxin	RelE-like toxin of type II toxin-antitoxin system HigB

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.2310.20	Alpha Beta	2-Layer Sandwich	YaeB-like fold	RelE-like	4mcxB00

4YY3Y 3G5OB 4ML0B 4MMJA 4MCTB 2A6RA 5CW7B 2KHEA 4FXHA 5CZFC 5IWHA 4FXED 4MMGA 4MCXB 4ML2A 2A6SA 4LTTA 3OEIC 3BPQB 2A6QE 2OTRA 4LS4A 5CZEB 5IXLA 4NRNA 4Q2UB 1WMIA 5CEGB 1Z8MA 4PX8A 2KC9A 4FXIA 4LSYA 3KXEA 2KC8A
chains in the Genus database with same CATH superfamily

2FHZB 4YY3Y 2A8KA 3G5OB 4ML0B 4MMJA 4MCTB 2A6RA 2DFXE 2KHEA 4FXHA 5CW7B 3KXEA 5CZFC 5IWHA 4FXED 3HI2B 4MMGA 4MCXB 4ML2A 4FBDA 2A6SA 4LTTA 3OEIC 3BPQB 2A6QE 2OTRA 4LS4A 5CZEB 5IXLA 2PD0A 3AO9A 4NRNA 4Q2UB 1WMIA 5CEGB 1Z8MA 4PX8A 1XQBA 2KC9A 4FXIA 4LSYA 2DJHA 3VJ7A 2KC8A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4YY3 Y;  3G5O B;  4ML0 B;  4MMJ A;  4MCT B;  2A6R A;  5CW7 B;  2KHE A;  4FXH A;  5CZF C;  5IWH A;  4FXE D;  4MMG A;  4MCX B;  4ML2 A;  2A6S A;  4LTT A;  3OEI C;  3BPQ B;  2A6Q E;  2OTR A;  4LS4 A;  5CZE B;  5IXL A;  4NRN A;  4Q2U B;  1WMI A;  5CEG B;  1Z8M A;  4PX8 A;  2KC9 A;  4FXI A;  4LSY A;  3KXE A;  2KC8 A; 
#chains in the Genus database with same CATH topology
 2FHZ B;  4YY3 Y;  2A8K A;  3G5O B;  4ML0 B;  4MMJ A;  4MCT B;  2A6R A;  2DFX E;  2KHE A;  4FXH A;  5CW7 B;  3KXE A;  5CZF C;  5IWH A;  4FXE D;  3HI2 B;  4MMG A;  4MCX B;  4ML2 A;  4FBD A;  2A6S A;  4LTT A;  3OEI C;  3BPQ B;  2A6Q E;  2OTR A;  4LS4 A;  5CZE B;  5IXL A;  2PD0 A;  3AO9 A;  4NRN A;  4Q2U B;  1WMI A;  5CEG B;  1Z8M A;  4PX8 A;  1XQB A;  2KC9 A;  4FXI A;  4LSY A;  2DJH A;  3VJ7 A;  2KC8 A; 
#chains in the Genus database with same CATH homology
 4YY3 Y;  3G5O B;  4ML0 B;  4MMJ A;  4MCT B;  2A6R A;  5CW7 B;  2KHE A;  4FXH A;  5CZF C;  5IWH A;  4FXE D;  4MMG A;  4MCX B;  4ML2 A;  2A6S A;  4LTT A;  3OEI C;  3BPQ B;  2A6Q E;  2OTR A;  4LS4 A;  5CZE B;  5IXL A;  4NRN A;  4Q2U B;  1WMI A;  5CEG B;  1Z8M A;  4PX8 A;  2KC9 A;  4FXI A;  4LSY A;  3KXE A;  2KC8 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4MCXB

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations