4MJPA

E. coli sliding clamp in complex with (r)-vedaprofen
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
364
structure length
361
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Escherichia coli
molecule keywords DNA polymerase III subunit beta
total genus 89
structure length 361
sequence length 364
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2013-09-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4mjpA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4mjpA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4mjpA01
5AGVA 1JQLA 3D1FA 4N97A 4PNVA 5AGUA 1OK7A 4MJRA 4TSZA 4K3OA 2AVTA 4N96A 5AH2A 4K3SA 4N99A 2POLA 3QSBB 2AWAA 3Q4KA 4TR7A 3L0WA 1MMIA 3D1GA 3PWEA 4OVHA 4K3QA 4TR6A 5FRQA 4MJPA 1JQJA 4K3MA 3PGEB 4K3PA 3T0PA 4N9AA 3L10A 4K3KA 5FVEA 4OVGA 3BEPA 4TR8A 4N94A 4PNWA 3F1VA 4PNUA 3Q4LA 4TRTA 5AH4A 3RB9A 1UNNA 2XURA 4N98A 3P16A 4N95A 4MJQA 4OVFA 1VPKA 3QSBA 4K3LA 4K3RA 4RKIA 4S3IA 3Q4JA 4K74A 3L0XA 3D1EA
chains in the Genus database with same CATH superfamily
5AGVA 1JQLA 3D1FA 4N97A 4PNVA 5AGUA 3PGEA 1OK7A 4MJRA 4TSZA 4K3OA 2AVTA 4N96A 5AH2A 4K3SA 4N99A 2POLA 3QSBB 2AWAA 3Q4KA 4TR7A 3L0WA 1MMIA 3D1GA 3PWEA 4OVHA 4K3QA 4TR6A 3L0XB 4MJPA 1JQJA 5FRQA 4K3MA 3PGEB 4K3PA 3T0PA 4N9AA 3L10A 4K3KA 5FVEA 4OVGA 3BEPA 3L0WB 4TR8A 4N94A 4PNWA 3F1VA 4PNUA 3L10B 3Q4LA 4TRTA 5AH4A 3RB9A 1UNNA 2XURA 4N98A 3P16A 4N95A 4MJQA 4OVFA 1VPKA 3QSBA 4K3LA 4K3RA 4RKIA 4S3IA 3Q4JA 4K74A 3L0XA 3D1EA
chains in the Genus database with same CATH topology
5AGVA 1JQLA 3D1FA 4N97A 4PNVA 5AGUA 1OK7A 4MJRA 4TSZA 4K3OA 2AVTA 4N96A 5AH2A 4K3SA 4N99A 2POLA 3QSBB 2AWAA 3Q4KA 4TR7A 3L0WA 1MMIA 3D1GA 3PWEA 4OVHA 4K3QA 4TR6A 5FRQA 4MJPA 1JQJA 4K3MA 3PGEB 4K3PA 3T0PA 4N9AA 3L10A 4K3KA 5FVEA 4OVGA 3BEPA 4TR8A 4N94A 4PNWA 3F1VA 4PNUA 3Q4LA 4TRTA 5AH4A 3RB9A 1UNNA 2XURA 4N98A 3P16A 4N95A 4MJQA 4OVFA 1VPKA 3QSBA 4K3LA 4K3RA 4RKIA 4S3IA 3Q4JA 4K74A 3L0XA 3D1EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AGV A;  1JQL A;  3D1F A;  4N97 A;  4PNV A;  5AGU A;  1OK7 A;  4MJR A;  4TSZ A;  4K3O A;  2AVT A;  4N96 A;  5AH2 A;  4K3S A;  4N99 A;  2POL A;  3QSB B;  2AWA A;  3Q4K A;  4TR7 A;  3L0W A;  1MMI A;  3D1G A;  3PWE A;  4OVH A;  4K3Q A;  4TR6 A;  5FRQ A;  4MJP A;  1JQJ A;  4K3M A;  3PGE B;  4K3P A;  3T0P A;  4N9A A;  3L10 A;  4K3K A;  5FVE A;  4OVG A;  3BEP A;  4TR8 A;  4N94 A;  4PNW A;  3F1V A;  4PNU A;  3Q4L A;  4TRT A;  5AH4 A;  3RB9 A;  1UNN A;  2XUR A;  4N98 A;  3P16 A;  4N95 A;  4MJQ A;  4OVF A;  1VPK A;  3QSB A;  4K3L A;  4K3R A;  4RKI A;  4S3I A;  3Q4J A;  4K74 A;  3L0X A;  3D1E A; 
#chains in the Genus database with same CATH topology
 5AGV A;  1JQL A;  3D1F A;  4N97 A;  4PNV A;  5AGU A;  3PGE A;  1OK7 A;  4MJR A;  4TSZ A;  4K3O A;  2AVT A;  4N96 A;  5AH2 A;  4K3S A;  4N99 A;  2POL A;  3QSB B;  2AWA A;  3Q4K A;  4TR7 A;  3L0W A;  1MMI A;  3D1G A;  3PWE A;  4OVH A;  4K3Q A;  4TR6 A;  3L0X B;  4MJP A;  1JQJ A;  5FRQ A;  4K3M A;  3PGE B;  4K3P A;  3T0P A;  4N9A A;  3L10 A;  4K3K A;  5FVE A;  4OVG A;  3BEP A;  3L0W B;  4TR8 A;  4N94 A;  4PNW A;  3F1V A;  4PNU A;  3L10 B;  3Q4L A;  4TRT A;  5AH4 A;  3RB9 A;  1UNN A;  2XUR A;  4N98 A;  3P16 A;  4N95 A;  4MJQ A;  4OVF A;  1VPK A;  3QSB A;  4K3L A;  4K3R A;  4RKI A;  4S3I A;  3Q4J A;  4K74 A;  3L0X A;  3D1E A; 
#chains in the Genus database with same CATH homology
 5AGV A;  1JQL A;  3D1F A;  4N97 A;  4PNV A;  5AGU A;  1OK7 A;  4MJR A;  4TSZ A;  4K3O A;  2AVT A;  4N96 A;  5AH2 A;  4K3S A;  4N99 A;  2POL A;  3QSB B;  2AWA A;  3Q4K A;  4TR7 A;  3L0W A;  1MMI A;  3D1G A;  3PWE A;  4OVH A;  4K3Q A;  4TR6 A;  5FRQ A;  4MJP A;  1JQJ A;  4K3M A;  3PGE B;  4K3P A;  3T0P A;  4N9A A;  3L10 A;  4K3K A;  5FVE A;  4OVG A;  3BEP A;  4TR8 A;  4N94 A;  4PNW A;  3F1V A;  4PNU A;  3Q4L A;  4TRT A;  5AH4 A;  3RB9 A;  1UNN A;  2XUR A;  4N98 A;  3P16 A;  4N95 A;  4MJQ A;  4OVF A;  1VPK A;  3QSB A;  4K3L A;  4K3R A;  4RKI A;  4S3I A;  3Q4J A;  4K74 A;  3L0X A;  3D1E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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