4MJPA

E. coli sliding clamp in complex with (r)-vedaprofen
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
364
structure length
361
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Escherichia coli
publication title DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
pubmed doi rcsb
molecule keywords DNA polymerase III subunit beta
total genus 89
structure length 361
sequence length 364
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2013-09-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4mjpA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4mjpA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4mjpA01
3T0PA 4K3PA 5FVEA 4MJPA 3D1GA 3PGEB 4N94A 4N97A 1JQJA 1JQLA 3L10A 3PWEA 3Q4KA 4PNWA 4K3KA 3D1FA 4K3OA 4TR7A 3P16A 2AWAA 5AGUA 3QSBA 2XURA 4K74A 4TSZA 4N9AA 4K3QA 3BEPA 4OVFA 1OK7A 3L0XA 3F1VA 3QSBB 4N95A 4N98A 4PNVA 4MJRA 4K3LA 3L0WA 4S3IA 3D1EA 1UNNA 5FRQA 5AGVA 3RB9A 4N96A 4OVGA 1MMIA 4RKIA 1VPKA 4OVHA 4TR6A 4N99A 4K3MA 4K3RA 2POLA 3Q4LA 2AVTA 4TRTA 4MJQA 3Q4JA 4K3SA 5AH2A 4PNUA 4TR8A 5AH4A
chains in the Genus database with same CATH superfamily
3T0PA 4K3PA 5FVEA 4MJPA 3D1GA 3PGEB 4N94A 4N97A 1JQJA 1JQLA 3L10A 3PWEA 3Q4KA 4PNWA 4K3KA 3D1FA 4K3OA 4TR7A 3P16A 2AWAA 5AGUA 3QSBA 2XURA 4K74A 4TSZA 4N9AA 4K3QA 3BEPA 4OVFA 1OK7A 3L0XA 3L10B 3F1VA 3QSBB 4N95A 4N98A 4PNVA 4MJRA 4K3LA 3L0WA 4S3IA 3D1EA 1UNNA 5FRQA 5AGVA 3RB9A 4N96A 4OVGA 1MMIA 4RKIA 1VPKA 3L0XB 4OVHA 4TR6A 4N99A 4K3MA 4K3RA 2POLA 3Q4LA 2AVTA 4TRTA 3L0WB 4MJQA 3PGEA 3Q4JA 4K3SA 5AH2A 4PNUA 4TR8A 5AH4A
chains in the Genus database with same CATH topology
3T0PA 4K3PA 5FVEA 4MJPA 3D1GA 3PGEB 4N94A 4N97A 1JQJA 1JQLA 3L10A 3PWEA 3Q4KA 4PNWA 4K3KA 3D1FA 4K3OA 4TR7A 3P16A 2AWAA 5AGUA 3QSBA 2XURA 4K74A 4TSZA 4N9AA 4K3QA 3BEPA 4OVFA 1OK7A 3L0XA 3F1VA 3QSBB 4N95A 4N98A 4PNVA 4MJRA 4K3LA 3L0WA 4S3IA 3D1EA 1UNNA 5FRQA 5AGVA 3RB9A 4N96A 4OVGA 1MMIA 4RKIA 1VPKA 4OVHA 4TR6A 4N99A 4K3MA 4K3RA 2POLA 3Q4LA 2AVTA 4TRTA 4MJQA 3Q4JA 4K3SA 5AH2A 4PNUA 4TR8A 5AH4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T0P A;  4K3P A;  5FVE A;  4MJP A;  3D1G A;  3PGE B;  4N94 A;  4N97 A;  1JQJ A;  1JQL A;  3L10 A;  3PWE A;  3Q4K A;  4PNW A;  4K3K A;  3D1F A;  4K3O A;  4TR7 A;  3P16 A;  2AWA A;  5AGU A;  3QSB A;  2XUR A;  4K74 A;  4TSZ A;  4N9A A;  4K3Q A;  3BEP A;  4OVF A;  1OK7 A;  3L0X A;  3F1V A;  3QSB B;  4N95 A;  4N98 A;  4PNV A;  4MJR A;  4K3L A;  3L0W A;  4S3I A;  3D1E A;  1UNN A;  5FRQ A;  5AGV A;  3RB9 A;  4N96 A;  4OVG A;  1MMI A;  4RKI A;  1VPK A;  4OVH A;  4TR6 A;  4N99 A;  4K3M A;  4K3R A;  2POL A;  3Q4L A;  2AVT A;  4TRT A;  4MJQ A;  3Q4J A;  4K3S A;  5AH2 A;  4PNU A;  4TR8 A;  5AH4 A; 
#chains in the Genus database with same CATH topology
 3T0P A;  4K3P A;  5FVE A;  4MJP A;  3D1G A;  3PGE B;  4N94 A;  4N97 A;  1JQJ A;  1JQL A;  3L10 A;  3PWE A;  3Q4K A;  4PNW A;  4K3K A;  3D1F A;  4K3O A;  4TR7 A;  3P16 A;  2AWA A;  5AGU A;  3QSB A;  2XUR A;  4K74 A;  4TSZ A;  4N9A A;  4K3Q A;  3BEP A;  4OVF A;  1OK7 A;  3L0X A;  3L10 B;  3F1V A;  3QSB B;  4N95 A;  4N98 A;  4PNV A;  4MJR A;  4K3L A;  3L0W A;  4S3I A;  3D1E A;  1UNN A;  5FRQ A;  5AGV A;  3RB9 A;  4N96 A;  4OVG A;  1MMI A;  4RKI A;  1VPK A;  3L0X B;  4OVH A;  4TR6 A;  4N99 A;  4K3M A;  4K3R A;  2POL A;  3Q4L A;  2AVT A;  4TRT A;  3L0W B;  4MJQ A;  3PGE A;  3Q4J A;  4K3S A;  5AH2 A;  4PNU A;  4TR8 A;  5AH4 A; 
#chains in the Genus database with same CATH homology
 3T0P A;  4K3P A;  5FVE A;  4MJP A;  3D1G A;  3PGE B;  4N94 A;  4N97 A;  1JQJ A;  1JQL A;  3L10 A;  3PWE A;  3Q4K A;  4PNW A;  4K3K A;  3D1F A;  4K3O A;  4TR7 A;  3P16 A;  2AWA A;  5AGU A;  3QSB A;  2XUR A;  4K74 A;  4TSZ A;  4N9A A;  4K3Q A;  3BEP A;  4OVF A;  1OK7 A;  3L0X A;  3F1V A;  3QSB B;  4N95 A;  4N98 A;  4PNV A;  4MJR A;  4K3L A;  3L0W A;  4S3I A;  3D1E A;  1UNN A;  5FRQ A;  5AGV A;  3RB9 A;  4N96 A;  4OVG A;  1MMI A;  4RKI A;  1VPK A;  4OVH A;  4TR6 A;  4N99 A;  4K3M A;  4K3R A;  2POL A;  3Q4L A;  2AVT A;  4TRT A;  4MJQ A;  3Q4J A;  4K3S A;  5AH2 A;  4PNU A;  4TR8 A;  5AH4 A; 
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similar chains in the Genus database (?% sequence similarity)
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