4N94 | Genus

Total Genus 87

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	87
sequence length	366
structure length	360
Chain Sequence	MKFTVEREHLLKPLQQVSGPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 360 atoms

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360 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Escherichia coli
publication title	Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. pubmed doi rcsb
molecule keywords	DNA polymerase III subunit beta
total genus	87
structure length	360
sequence length	366
chains with identical sequence	B
ec nomenclature	ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date	2013-10-19

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00712	DNA_pol3_beta	DNA polymerase III beta subunit, N-terminal domain
A	PF02767	DNA_pol3_beta_2	DNA polymerase III beta subunit, central domain
A	PF02768	DNA_pol3_beta_3	DNA polymerase III beta subunit, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4n94A02
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4n94A03
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4n94A01

3RB9A 4K3PA 4N96A 4S3IA 3PGEB 3L0XA 3QSBB 4N98A 4K3QA 4TR7A 2AVTA 4MJQA 5AGVA 3D1EA 4N9AA 3D1GA 3Q4JA 4K3OA 5AH4A 4TRTA 4OVGA 4K3RA 1VPKA 4N97A 1MMIA 4MJRA 1JQJA 4OVFA 4N95A 5AH2A 4N99A 4PNVA 2POLA 1OK7A 3QSBA 4RKIA 4TR6A 3BEPA 4K3SA 3F1VA 5FRQA 3L10A 3P16A 1JQLA 2XURA 3Q4LA 4K3KA 3Q4KA 4MJPA 4TSZA 3D1FA 1UNNA 4PNUA 4N94A 4K3MA 4OVHA 4PNWA 3PWEA 4TR8A 2AWAA 5FVEA 4K3LA 4K74A 5AGUA 3T0PA 3L0WA
chains in the Genus database with same CATH superfamily

3RB9A 4K3PA 4N96A 4S3IA 3PGEB 3L0XA 3QSBB 4N98A 4K3QA 4TR7A 2AVTA 4MJQA 5AGVA 3D1EA 4N9AA 3L10B 3D1GA 3Q4JA 4K3OA 5AH4A 4TRTA 4OVGA 4K3RA 1VPKA 4N97A 1MMIA 4MJRA 1JQJA 4OVFA 4N95A 5AH2A 3PGEA 4N99A 4PNVA 2POLA 1OK7A 3QSBA 4RKIA 4TR6A 3BEPA 4K3SA 3F1VA 5FRQA 3L10A 3P16A 1JQLA 2XURA 3Q4LA 4K3KA 3Q4KA 4MJPA 4TSZA 3D1FA 3L0WB 1UNNA 4PNUA 4N94A 4K3MA 4OVHA 3L0XB 4PNWA 3PWEA 4TR8A 2AWAA 5FVEA 4K3LA 4K74A 5AGUA 3T0PA 3L0WA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3RB9 A;  4K3P A;  4N96 A;  4S3I A;  3PGE B;  3L0X A;  3QSB B;  4N98 A;  4K3Q A;  4TR7 A;  2AVT A;  4MJQ A;  5AGV A;  3D1E A;  4N9A A;  3D1G A;  3Q4J A;  4K3O A;  5AH4 A;  4TRT A;  4OVG A;  4K3R A;  1VPK A;  4N97 A;  1MMI A;  4MJR A;  1JQJ A;  4OVF A;  4N95 A;  5AH2 A;  4N99 A;  4PNV A;  2POL A;  1OK7 A;  3QSB A;  4RKI A;  4TR6 A;  3BEP A;  4K3S A;  3F1V A;  5FRQ A;  3L10 A;  3P16 A;  1JQL A;  2XUR A;  3Q4L A;  4K3K A;  3Q4K A;  4MJP A;  4TSZ A;  3D1F A;  1UNN A;  4PNU A;  4N94 A;  4K3M A;  4OVH A;  4PNW A;  3PWE A;  4TR8 A;  2AWA A;  5FVE A;  4K3L A;  4K74 A;  5AGU A;  3T0P A;  3L0W A; 
#chains in the Genus database with same CATH topology
 3RB9 A;  4K3P A;  4N96 A;  4S3I A;  3PGE B;  3L0X A;  3QSB B;  4N98 A;  4K3Q A;  4TR7 A;  2AVT A;  4MJQ A;  5AGV A;  3D1E A;  4N9A A;  3L10 B;  3D1G A;  3Q4J A;  4K3O A;  5AH4 A;  4TRT A;  4OVG A;  4K3R A;  1VPK A;  4N97 A;  1MMI A;  4MJR A;  1JQJ A;  4OVF A;  4N95 A;  5AH2 A;  3PGE A;  4N99 A;  4PNV A;  2POL A;  1OK7 A;  3QSB A;  4RKI A;  4TR6 A;  3BEP A;  4K3S A;  3F1V A;  5FRQ A;  3L10 A;  3P16 A;  1JQL A;  2XUR A;  3Q4L A;  4K3K A;  3Q4K A;  4MJP A;  4TSZ A;  3D1F A;  3L0W B;  1UNN A;  4PNU A;  4N94 A;  4K3M A;  4OVH A;  3L0X B;  4PNW A;  3PWE A;  4TR8 A;  2AWA A;  5FVE A;  4K3L A;  4K74 A;  5AGU A;  3T0P A;  3L0W A; 
#chains in the Genus database with same CATH homology
 3RB9 A;  4K3P A;  4N96 A;  4S3I A;  3PGE B;  3L0X A;  3QSB B;  4N98 A;  4K3Q A;  4TR7 A;  2AVT A;  4MJQ A;  5AGV A;  3D1E A;  4N9A A;  3D1G A;  3Q4J A;  4K3O A;  5AH4 A;  4TRT A;  4OVG A;  4K3R A;  1VPK A;  4N97 A;  1MMI A;  4MJR A;  1JQJ A;  4OVF A;  4N95 A;  5AH2 A;  4N99 A;  4PNV A;  2POL A;  1OK7 A;  3QSB A;  4RKI A;  4TR6 A;  3BEP A;  4K3S A;  3F1V A;  5FRQ A;  3L10 A;  3P16 A;  1JQL A;  2XUR A;  3Q4L A;  4K3K A;  3Q4K A;  4MJP A;  4TSZ A;  3D1F A;  1UNN A;  4PNU A;  4N94 A;  4K3M A;  4OVH A;  4PNW A;  3PWE A;  4TR8 A;  2AWA A;  5FVE A;  4K3L A;  4K74 A;  5AGU A;  3T0P A;  3L0W A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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4N94A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations