4N96 | Genus

Total Genus 87

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	87
sequence length	366
structure length	356
Chain Sequence	MKFTVEREHLLKPLQQVSPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 356 atoms

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356 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Escherichia coli
publication title	Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. pubmed doi rcsb
molecule keywords	DNA polymerase III subunit beta
total genus	87
structure length	356
sequence length	366
chains with identical sequence	B
ec nomenclature	ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date	2013-10-19

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00712	DNA_pol3_beta	DNA polymerase III beta subunit, N-terminal domain
A	PF02767	DNA_pol3_beta_2	DNA polymerase III beta subunit, central domain
A	PF02768	DNA_pol3_beta_3	DNA polymerase III beta subunit, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4n96A02
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4n96A03
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4n96A01

3QSBA 4K3QA 2XURA 3L0XA 3PGEB 4N9AA 4K3MA 2AVTA 4MJQA 1VPKA 4K3SA 5AH4A 3T0PA 4TR6A 5FVEA 4PNWA 4TR7A 5FRQA 3RB9A 4N97A 1MMIA 3Q4LA 4N98A 4RKIA 3QSBB 4PNUA 3F1VA 3L0WA 3D1EA 4K3LA 4N94A 1JQLA 5AH2A 4TRTA 4OVHA 3L10A 3PWEA 4K74A 4OVFA 4OVGA 4TR8A 2AWAA 4K3RA 3Q4JA 4K3KA 4N95A 2POLA 1JQJA 4K3OA 3D1GA 4MJRA 4S3IA 3Q4KA 4K3PA 5AGUA 1UNNA 4N99A 4N96A 4TSZA 4PNVA 1OK7A 4MJPA 3BEPA 5AGVA 3P16A 3D1FA
chains in the Genus database with same CATH superfamily

3QSBA 4K3QA 2XURA 3L0XA 3PGEB 3L10B 4N9AA 4K3MA 2AVTA 4MJQA 1VPKA 4K3SA 5AH4A 3T0PA 4TR6A 5FVEA 4PNWA 4TR7A 5FRQA 5AGVA 3RB9A 4N97A 1MMIA 3Q4LA 4N98A 4RKIA 3QSBB 4PNUA 3F1VA 3L0WA 3D1EA 4K3LA 4N94A 1JQLA 3L0XB 5AH2A 4TRTA 4OVHA 3L10A 3PWEA 4K74A 4OVFA 4OVGA 3PGEA 4TR8A 2AWAA 4K3RA 3Q4JA 4K3KA 4N95A 2POLA 1JQJA 4K3OA 3D1GA 4MJRA 4S3IA 3Q4KA 4K3PA 5AGUA 1UNNA 4N99A 4N96A 4TSZA 4PNVA 1OK7A 4MJPA 3BEPA 3L0WB 3P16A 3D1FA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3QSB A;  4K3Q A;  2XUR A;  3L0X A;  3PGE B;  4N9A A;  4K3M A;  2AVT A;  4MJQ A;  1VPK A;  4K3S A;  5AH4 A;  3T0P A;  4TR6 A;  5FVE A;  4PNW A;  4TR7 A;  5FRQ A;  3RB9 A;  4N97 A;  1MMI A;  3Q4L A;  4N98 A;  4RKI A;  3QSB B;  4PNU A;  3F1V A;  3L0W A;  3D1E A;  4K3L A;  4N94 A;  1JQL A;  5AH2 A;  4TRT A;  4OVH A;  3L10 A;  3PWE A;  4K74 A;  4OVF A;  4OVG A;  4TR8 A;  2AWA A;  4K3R A;  3Q4J A;  4K3K A;  4N95 A;  2POL A;  1JQJ A;  4K3O A;  3D1G A;  4MJR A;  4S3I A;  3Q4K A;  4K3P A;  5AGU A;  1UNN A;  4N99 A;  4N96 A;  4TSZ A;  4PNV A;  1OK7 A;  4MJP A;  3BEP A;  5AGV A;  3P16 A;  3D1F A; 
#chains in the Genus database with same CATH topology
 3QSB A;  4K3Q A;  2XUR A;  3L0X A;  3PGE B;  3L10 B;  4N9A A;  4K3M A;  2AVT A;  4MJQ A;  1VPK A;  4K3S A;  5AH4 A;  3T0P A;  4TR6 A;  5FVE A;  4PNW A;  4TR7 A;  5FRQ A;  5AGV A;  3RB9 A;  4N97 A;  1MMI A;  3Q4L A;  4N98 A;  4RKI A;  3QSB B;  4PNU A;  3F1V A;  3L0W A;  3D1E A;  4K3L A;  4N94 A;  1JQL A;  3L0X B;  5AH2 A;  4TRT A;  4OVH A;  3L10 A;  3PWE A;  4K74 A;  4OVF A;  4OVG A;  3PGE A;  4TR8 A;  2AWA A;  4K3R A;  3Q4J A;  4K3K A;  4N95 A;  2POL A;  1JQJ A;  4K3O A;  3D1G A;  4MJR A;  4S3I A;  3Q4K A;  4K3P A;  5AGU A;  1UNN A;  4N99 A;  4N96 A;  4TSZ A;  4PNV A;  1OK7 A;  4MJP A;  3BEP A;  3L0W B;  3P16 A;  3D1F A; 
#chains in the Genus database with same CATH homology
 3QSB A;  4K3Q A;  2XUR A;  3L0X A;  3PGE B;  4N9A A;  4K3M A;  2AVT A;  4MJQ A;  1VPK A;  4K3S A;  5AH4 A;  3T0P A;  4TR6 A;  5FVE A;  4PNW A;  4TR7 A;  5FRQ A;  3RB9 A;  4N97 A;  1MMI A;  3Q4L A;  4N98 A;  4RKI A;  3QSB B;  4PNU A;  3F1V A;  3L0W A;  3D1E A;  4K3L A;  4N94 A;  1JQL A;  5AH2 A;  4TRT A;  4OVH A;  3L10 A;  3PWE A;  4K74 A;  4OVF A;  4OVG A;  4TR8 A;  2AWA A;  4K3R A;  3Q4J A;  4K3K A;  4N95 A;  2POL A;  1JQJ A;  4K3O A;  3D1G A;  4MJR A;  4S3I A;  3Q4K A;  4K3P A;  5AGU A;  1UNN A;  4N99 A;  4N96 A;  4TSZ A;  4PNV A;  1OK7 A;  4MJP A;  3BEP A;  5AGV A;  3P16 A;  3D1F A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4N96A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations