4N97 | Genus

Total Genus 89

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	89
sequence length	366
structure length	361
Chain Sequence	MKFTVEREHLLKPLQQVSGPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 361 atoms

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361 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Escherichia coli
publication title	Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. pubmed doi rcsb
molecule keywords	DNA polymerase III subunit beta
total genus	89
structure length	361
sequence length	366
chains with identical sequence	B
ec nomenclature	ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date	2013-10-19

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00712	DNA_pol3_beta	DNA polymerase III beta subunit, N-terminal domain
A	PF02767	DNA_pol3_beta_2	DNA polymerase III beta subunit, central domain
A	PF02768	DNA_pol3_beta_3	DNA polymerase III beta subunit, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4n97A02
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4n97A03
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	4n97A01

1UNNA 4N9AA 4MJRA 4N94A 4OVGA 3PGEB 3Q4JA 4MJPA 3D1FA 4N98A 2XURA 3F1VA 4K3OA 3L0XA 4TR8A 4N96A 5AH2A 1JQLA 2AWAA 4TR7A 3L10A 2AVTA 3Q4KA 3P16A 4K3SA 1JQJA 4N97A 4OVFA 4K74A 4PNUA 4S3IA 3T0PA 4TSZA 5AGVA 4OVHA 4RKIA 3RB9A 4N95A 1OK7A 5AH4A 4K3MA 4MJQA 4K3RA 3L0WA 4K3LA 5AGUA 1VPKA 5FVEA 3QSBB 3QSBA 4PNVA 4TRTA 4K3KA 5FRQA 1MMIA 3D1EA 3D1GA 4K3PA 4PNWA 3BEPA 3PWEA 2POLA 4N99A 4K3QA 3Q4LA 4TR6A
chains in the Genus database with same CATH superfamily

1UNNA 4N9AA 3PGEA 4MJRA 4N94A 4OVGA 3PGEB 3Q4JA 4MJPA 3D1FA 4N98A 2XURA 3F1VA 4K3OA 3L0XA 4TR8A 4N96A 3L0XB 5AH2A 1JQLA 2AWAA 4TR7A 3L10A 2AVTA 3Q4KA 3L10B 3P16A 4K3SA 1JQJA 4N97A 4OVFA 4K74A 4PNUA 4S3IA 3T0PA 4TSZA 5AGVA 4OVHA 4RKIA 3RB9A 4N95A 1OK7A 5AH4A 4K3MA 4MJQA 4K3RA 3L0WA 4K3LA 5AGUA 1VPKA 3L0WB 5FVEA 3QSBB 3QSBA 4PNVA 4TRTA 4K3KA 5FRQA 1MMIA 3D1EA 3D1GA 4K3PA 4PNWA 3BEPA 3PWEA 2POLA 4N99A 4K3QA 3Q4LA 4TR6A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1UNN A;  4N9A A;  4MJR A;  4N94 A;  4OVG A;  3PGE B;  3Q4J A;  4MJP A;  3D1F A;  4N98 A;  2XUR A;  3F1V A;  4K3O A;  3L0X A;  4TR8 A;  4N96 A;  5AH2 A;  1JQL A;  2AWA A;  4TR7 A;  3L10 A;  2AVT A;  3Q4K A;  3P16 A;  4K3S A;  1JQJ A;  4N97 A;  4OVF A;  4K74 A;  4PNU A;  4S3I A;  3T0P A;  4TSZ A;  5AGV A;  4OVH A;  4RKI A;  3RB9 A;  4N95 A;  1OK7 A;  5AH4 A;  4K3M A;  4MJQ A;  4K3R A;  3L0W A;  4K3L A;  5AGU A;  1VPK A;  5FVE A;  3QSB B;  3QSB A;  4PNV A;  4TRT A;  4K3K A;  5FRQ A;  1MMI A;  3D1E A;  3D1G A;  4K3P A;  4PNW A;  3BEP A;  3PWE A;  2POL A;  4N99 A;  4K3Q A;  3Q4L A;  4TR6 A; 
#chains in the Genus database with same CATH topology
 1UNN A;  4N9A A;  3PGE A;  4MJR A;  4N94 A;  4OVG A;  3PGE B;  3Q4J A;  4MJP A;  3D1F A;  4N98 A;  2XUR A;  3F1V A;  4K3O A;  3L0X A;  4TR8 A;  4N96 A;  3L0X B;  5AH2 A;  1JQL A;  2AWA A;  4TR7 A;  3L10 A;  2AVT A;  3Q4K A;  3L10 B;  3P16 A;  4K3S A;  1JQJ A;  4N97 A;  4OVF A;  4K74 A;  4PNU A;  4S3I A;  3T0P A;  4TSZ A;  5AGV A;  4OVH A;  4RKI A;  3RB9 A;  4N95 A;  1OK7 A;  5AH4 A;  4K3M A;  4MJQ A;  4K3R A;  3L0W A;  4K3L A;  5AGU A;  1VPK A;  3L0W B;  5FVE A;  3QSB B;  3QSB A;  4PNV A;  4TRT A;  4K3K A;  5FRQ A;  1MMI A;  3D1E A;  3D1G A;  4K3P A;  4PNW A;  3BEP A;  3PWE A;  2POL A;  4N99 A;  4K3Q A;  3Q4L A;  4TR6 A; 
#chains in the Genus database with same CATH homology
 1UNN A;  4N9A A;  4MJR A;  4N94 A;  4OVG A;  3PGE B;  3Q4J A;  4MJP A;  3D1F A;  4N98 A;  2XUR A;  3F1V A;  4K3O A;  3L0X A;  4TR8 A;  4N96 A;  5AH2 A;  1JQL A;  2AWA A;  4TR7 A;  3L10 A;  2AVT A;  3Q4K A;  3P16 A;  4K3S A;  1JQJ A;  4N97 A;  4OVF A;  4K74 A;  4PNU A;  4S3I A;  3T0P A;  4TSZ A;  5AGV A;  4OVH A;  4RKI A;  3RB9 A;  4N95 A;  1OK7 A;  5AH4 A;  4K3M A;  4MJQ A;  4K3R A;  3L0W A;  4K3L A;  5AGU A;  1VPK A;  5FVE A;  3QSB B;  3QSB A;  4PNV A;  4TRT A;  4K3K A;  5FRQ A;  1MMI A;  3D1E A;  3D1G A;  4K3P A;  4PNW A;  3BEP A;  3PWE A;  2POL A;  4N99 A;  4K3Q A;  3Q4L A;  4TR6 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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4N97A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations