4OVGA

E. coli sliding clamp in complex with (r)-9-(2-amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1h-carbazole-2-carboxylic acid
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
366
structure length
361
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Escherichia coli
molecule keywords DNA polymerase III subunit beta
total genus 87
structure length 361
sequence length 366
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2014-02-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovgA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovgA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovgA01
3F1VA 4N98A 4TR7A 4S3IA 4RKIA 3D1GA 3Q4JA 4PNVA 5FVEA 3L0XA 3QSBA 4N99A 5FRQA 5AGVA 2POLA 3T0PA 4TRTA 3QSBB 4TSZA 3P16A 5AH4A 2AVTA 2XURA 1JQJA 4K3OA 3PWEA 1VPKA 4PNUA 4TR8A 4K3LA 3PGEB 4K3SA 4K3QA 2AWAA 3Q4KA 1JQLA 3Q4LA 3L10A 4K3RA 4MJRA 4N97A 3BEPA 4K3PA 4K3MA 4OVHA 5AGUA 4N9AA 3D1FA 4N96A 4N94A 1MMIA 3RB9A 4K74A 4MJQA 1UNNA 4K3KA 4OVGA 4PNWA 4OVFA 4N95A 5AH2A 3D1EA 4MJPA 4TR6A 1OK7A 3L0WA
chains in the Genus database with same CATH superfamily
3F1VA 4N98A 4TR7A 4S3IA 4RKIA 3D1GA 3L0WB 3Q4JA 4PNVA 5FVEA 3L0XA 3QSBA 4N99A 5FRQA 5AGVA 2POLA 3T0PA 3L0XB 3QSBB 4TRTA 3P16A 4TSZA 5AH4A 2AVTA 2XURA 1JQJA 4K3OA 3PWEA 1VPKA 4PNUA 3PGEA 4TR8A 4K3LA 3PGEB 4K3SA 4K3QA 2AWAA 3Q4KA 1JQLA 3Q4LA 3L10A 4K3RA 4MJRA 4N97A 3BEPA 4K3PA 3L10B 4K3MA 4OVHA 5AGUA 4N9AA 3D1FA 4N96A 4N94A 1MMIA 3RB9A 4K74A 4MJQA 1UNNA 4K3KA 4OVGA 4PNWA 4OVFA 4N95A 5AH2A 3D1EA 4MJPA 4TR6A 1OK7A 3L0WA
chains in the Genus database with same CATH topology
3F1VA 4N98A 4TR7A 4S3IA 4RKIA 3D1GA 3Q4JA 4PNVA 5FVEA 3L0XA 3QSBA 4N99A 5FRQA 5AGVA 2POLA 3T0PA 4TRTA 3QSBB 4TSZA 3P16A 5AH4A 2AVTA 2XURA 1JQJA 4K3OA 3PWEA 1VPKA 4PNUA 4TR8A 4K3LA 3PGEB 4K3SA 4K3QA 2AWAA 3Q4KA 1JQLA 3Q4LA 3L10A 4K3RA 4MJRA 4N97A 3BEPA 4K3PA 4K3MA 4OVHA 5AGUA 4N9AA 3D1FA 4N96A 4N94A 1MMIA 3RB9A 4K74A 4MJQA 1UNNA 4K3KA 4OVGA 4PNWA 4OVFA 4N95A 5AH2A 3D1EA 4MJPA 4TR6A 1OK7A 3L0WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F1V A;  4N98 A;  4TR7 A;  4S3I A;  4RKI A;  3D1G A;  3Q4J A;  4PNV A;  5FVE A;  3L0X A;  3QSB A;  4N99 A;  5FRQ A;  5AGV A;  2POL A;  3T0P A;  4TRT A;  3QSB B;  4TSZ A;  3P16 A;  5AH4 A;  2AVT A;  2XUR A;  1JQJ A;  4K3O A;  3PWE A;  1VPK A;  4PNU A;  4TR8 A;  4K3L A;  3PGE B;  4K3S A;  4K3Q A;  2AWA A;  3Q4K A;  1JQL A;  3Q4L A;  3L10 A;  4K3R A;  4MJR A;  4N97 A;  3BEP A;  4K3P A;  4K3M A;  4OVH A;  5AGU A;  4N9A A;  3D1F A;  4N96 A;  4N94 A;  1MMI A;  3RB9 A;  4K74 A;  4MJQ A;  1UNN A;  4K3K A;  4OVG A;  4PNW A;  4OVF A;  4N95 A;  5AH2 A;  3D1E A;  4MJP A;  4TR6 A;  1OK7 A;  3L0W A; 
#chains in the Genus database with same CATH topology
 3F1V A;  4N98 A;  4TR7 A;  4S3I A;  4RKI A;  3D1G A;  3L0W B;  3Q4J A;  4PNV A;  5FVE A;  3L0X A;  3QSB A;  4N99 A;  5FRQ A;  5AGV A;  2POL A;  3T0P A;  3L0X B;  3QSB B;  4TRT A;  3P16 A;  4TSZ A;  5AH4 A;  2AVT A;  2XUR A;  1JQJ A;  4K3O A;  3PWE A;  1VPK A;  4PNU A;  3PGE A;  4TR8 A;  4K3L A;  3PGE B;  4K3S A;  4K3Q A;  2AWA A;  3Q4K A;  1JQL A;  3Q4L A;  3L10 A;  4K3R A;  4MJR A;  4N97 A;  3BEP A;  4K3P A;  3L10 B;  4K3M A;  4OVH A;  5AGU A;  4N9A A;  3D1F A;  4N96 A;  4N94 A;  1MMI A;  3RB9 A;  4K74 A;  4MJQ A;  1UNN A;  4K3K A;  4OVG A;  4PNW A;  4OVF A;  4N95 A;  5AH2 A;  3D1E A;  4MJP A;  4TR6 A;  1OK7 A;  3L0W A; 
#chains in the Genus database with same CATH homology
 3F1V A;  4N98 A;  4TR7 A;  4S3I A;  4RKI A;  3D1G A;  3Q4J A;  4PNV A;  5FVE A;  3L0X A;  3QSB A;  4N99 A;  5FRQ A;  5AGV A;  2POL A;  3T0P A;  4TRT A;  3QSB B;  4TSZ A;  3P16 A;  5AH4 A;  2AVT A;  2XUR A;  1JQJ A;  4K3O A;  3PWE A;  1VPK A;  4PNU A;  4TR8 A;  4K3L A;  3PGE B;  4K3S A;  4K3Q A;  2AWA A;  3Q4K A;  1JQL A;  3Q4L A;  3L10 A;  4K3R A;  4MJR A;  4N97 A;  3BEP A;  4K3P A;  4K3M A;  4OVH A;  5AGU A;  4N9A A;  3D1F A;  4N96 A;  4N94 A;  1MMI A;  3RB9 A;  4K74 A;  4MJQ A;  1UNN A;  4K3K A;  4OVG A;  4PNW A;  4OVF A;  4N95 A;  5AH2 A;  3D1E A;  4MJP A;  4TR6 A;  1OK7 A;  3L0W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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