4OVGA

E. coli sliding clamp in complex with (r)-9-(2-amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1h-carbazole-2-carboxylic acid
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
366
structure length
361
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Escherichia coli
molecule keywords DNA polymerase III subunit beta
total genus 87
structure length 361
sequence length 366
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2014-02-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovgA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovgA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovgA01
4TSZA 4TR6A 3D1FA 3PGEB 3Q4JA 3QSBA 2AWAA 5AH2A 3QSBB 4K3QA 3F1VA 3P16A 5FVEA 1MMIA 2AVTA 1JQLA 4K74A 4PNVA 3T0PA 3D1GA 3Q4LA 4N97A 5AGUA 4N9AA 2POLA 4PNWA 2XURA 4N99A 3BEPA 4MJRA 4TRTA 3PWEA 4N94A 3L0WA 4OVHA 4RKIA 1JQJA 4N95A 4K3PA 1UNNA 3L0XA 4MJQA 4K3RA 4N98A 3L10A 4MJPA 4TR8A 4K3LA 5FRQA 4OVGA 1OK7A 4N96A 4PNUA 3RB9A 4TR7A 4K3SA 5AGVA 1VPKA 4K3MA 4K3OA 3Q4KA 5AH4A 3D1EA 4K3KA 4OVFA 4S3IA
chains in the Genus database with same CATH superfamily
4TSZA 4TR6A 3D1FA 3PGEB 3Q4JA 3QSBA 4OVFA 2AWAA 5AH2A 3QSBB 4K3QA 3F1VA 3P16A 5FVEA 1MMIA 2AVTA 1JQLA 4K74A 4PNVA 3T0PA 3D1GA 3Q4LA 4N97A 5AGUA 4N9AA 2POLA 4PNWA 2XURA 4N99A 3BEPA 4MJRA 4TRTA 3PWEA 4N94A 3L0WA 4OVHA 4RKIA 1JQJA 3L0WB 4N95A 4K3PA 1UNNA 3L0XA 4MJQA 4K3RA 4N98A 3L0XB 3L10A 4MJPA 4TR8A 4K3LA 5FRQA 4OVGA 1OK7A 4N96A 4PNUA 3RB9A 3L10B 4TR7A 4K3SA 5AGVA 1VPKA 4K3MA 4K3OA 3Q4KA 5AH4A 3D1EA 4K3KA 3PGEA 4S3IA
chains in the Genus database with same CATH topology
4TSZA 4TR6A 3D1FA 3PGEB 3Q4JA 3QSBA 2AWAA 5AH2A 3QSBB 4K3QA 3F1VA 3P16A 5FVEA 1MMIA 2AVTA 1JQLA 4K74A 4PNVA 3T0PA 3D1GA 3Q4LA 4N97A 5AGUA 4N9AA 2POLA 4PNWA 2XURA 4N99A 3BEPA 4MJRA 4TRTA 3PWEA 4N94A 3L0WA 4OVHA 4RKIA 1JQJA 4N95A 4K3PA 1UNNA 3L0XA 4MJQA 4K3RA 4N98A 3L10A 4MJPA 4TR8A 4K3LA 5FRQA 4OVGA 1OK7A 4N96A 4PNUA 3RB9A 4TR7A 4K3SA 5AGVA 1VPKA 4K3MA 4K3OA 3Q4KA 5AH4A 3D1EA 4K3KA 4OVFA 4S3IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TSZ A;  4TR6 A;  3D1F A;  3PGE B;  3Q4J A;  3QSB A;  2AWA A;  5AH2 A;  3QSB B;  4K3Q A;  3F1V A;  3P16 A;  5FVE A;  1MMI A;  2AVT A;  1JQL A;  4K74 A;  4PNV A;  3T0P A;  3D1G A;  3Q4L A;  4N97 A;  5AGU A;  4N9A A;  2POL A;  4PNW A;  2XUR A;  4N99 A;  3BEP A;  4MJR A;  4TRT A;  3PWE A;  4N94 A;  3L0W A;  4OVH A;  4RKI A;  1JQJ A;  4N95 A;  4K3P A;  1UNN A;  3L0X A;  4MJQ A;  4K3R A;  4N98 A;  3L10 A;  4MJP A;  4TR8 A;  4K3L A;  5FRQ A;  4OVG A;  1OK7 A;  4N96 A;  4PNU A;  3RB9 A;  4TR7 A;  4K3S A;  5AGV A;  1VPK A;  4K3M A;  4K3O A;  3Q4K A;  5AH4 A;  3D1E A;  4K3K A;  4OVF A;  4S3I A; 
#chains in the Genus database with same CATH topology
 4TSZ A;  4TR6 A;  3D1F A;  3PGE B;  3Q4J A;  3QSB A;  4OVF A;  2AWA A;  5AH2 A;  3QSB B;  4K3Q A;  3F1V A;  3P16 A;  5FVE A;  1MMI A;  2AVT A;  1JQL A;  4K74 A;  4PNV A;  3T0P A;  3D1G A;  3Q4L A;  4N97 A;  5AGU A;  4N9A A;  2POL A;  4PNW A;  2XUR A;  4N99 A;  3BEP A;  4MJR A;  4TRT A;  3PWE A;  4N94 A;  3L0W A;  4OVH A;  4RKI A;  1JQJ A;  3L0W B;  4N95 A;  4K3P A;  1UNN A;  3L0X A;  4MJQ A;  4K3R A;  4N98 A;  3L0X B;  3L10 A;  4MJP A;  4TR8 A;  4K3L A;  5FRQ A;  4OVG A;  1OK7 A;  4N96 A;  4PNU A;  3RB9 A;  3L10 B;  4TR7 A;  4K3S A;  5AGV A;  1VPK A;  4K3M A;  4K3O A;  3Q4K A;  5AH4 A;  3D1E A;  4K3K A;  3PGE A;  4S3I A; 
#chains in the Genus database with same CATH homology
 4TSZ A;  4TR6 A;  3D1F A;  3PGE B;  3Q4J A;  3QSB A;  2AWA A;  5AH2 A;  3QSB B;  4K3Q A;  3F1V A;  3P16 A;  5FVE A;  1MMI A;  2AVT A;  1JQL A;  4K74 A;  4PNV A;  3T0P A;  3D1G A;  3Q4L A;  4N97 A;  5AGU A;  4N9A A;  2POL A;  4PNW A;  2XUR A;  4N99 A;  3BEP A;  4MJR A;  4TRT A;  3PWE A;  4N94 A;  3L0W A;  4OVH A;  4RKI A;  1JQJ A;  4N95 A;  4K3P A;  1UNN A;  3L0X A;  4MJQ A;  4K3R A;  4N98 A;  3L10 A;  4MJP A;  4TR8 A;  4K3L A;  5FRQ A;  4OVG A;  1OK7 A;  4N96 A;  4PNU A;  3RB9 A;  4TR7 A;  4K3S A;  5AGV A;  1VPK A;  4K3M A;  4K3O A;  3Q4K A;  5AH4 A;  3D1E A;  4K3K A;  4OVF A;  4S3I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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