4OVHA

E. coli sliding clamp in complex with (r)-6-bromo-9-(2-(carboxymethylamino)-2-oxoethyl)-2,3,4,9-tetrahydro-1h-carbazole-2-carboxylic acid
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
364
structure length
362
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGGRLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Escherichia coli
publication title Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs.
pubmed doi rcsb
molecule keywords DNA polymerase III subunit beta
total genus 89
structure length 362
sequence length 364
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2014-02-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovhA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovhA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovhA01
4N9AA 3D1FA 4MJQA 5AH2A 1UNNA 3T0PA 4K3MA 3PGEB 4N99A 4K3PA 3RB9A 3P16A 4TR6A 4PNWA 3D1EA 4N98A 1VPKA 3F1VA 1JQJA 3Q4LA 3QSBA 4K3SA 2XURA 5AGUA 2POLA 4OVHA 4N94A 3L10A 4K3OA 3Q4JA 3BEPA 3D1GA 4K3KA 4MJPA 4K3LA 5AGVA 4PNVA 4K3RA 4OVFA 4S3IA 4N96A 5AH4A 3Q4KA 4N97A 4N95A 1MMIA 4TRTA 4K3QA 4TR8A 4RKIA 4TR7A 1JQLA 1OK7A 5FRQA 5FVEA 2AWAA 4K74A 4PNUA 3QSBB 3L0XA 4MJRA 4OVGA 3PWEA 2AVTA 4TSZA 3L0WA
chains in the Genus database with same CATH superfamily
4N9AA 3L10B 3D1FA 4MJQA 5AH2A 1UNNA 3T0PA 4K3MA 3PGEB 4N99A 4K3PA 3RB9A 3P16A 4TR6A 4PNWA 3D1EA 4N98A 1VPKA 3F1VA 1JQJA 3Q4LA 3QSBA 4K3SA 2XURA 5AGUA 2POLA 4OVHA 4N94A 3L10A 4K3OA 3Q4JA 3BEPA 3D1GA 4K3KA 4MJPA 4K3LA 5AGVA 4PNVA 4K3RA 3L0XB 4OVFA 4N96A 4S3IA 5AH4A 3L0WB 3PGEA 3Q4KA 4N97A 4N95A 1MMIA 4TRTA 4K3QA 4TR8A 4RKIA 4TR7A 1JQLA 1OK7A 5FRQA 5FVEA 2AWAA 4K74A 4PNUA 3QSBB 3L0XA 4MJRA 4OVGA 3PWEA 2AVTA 4TSZA 3L0WA
chains in the Genus database with same CATH topology
4N9AA 3D1FA 4MJQA 5AH2A 1UNNA 3T0PA 4K3MA 3PGEB 4N99A 4K3PA 3RB9A 3P16A 4TR6A 4PNWA 3D1EA 4N98A 1VPKA 3F1VA 1JQJA 3Q4LA 3QSBA 4K3SA 2XURA 5AGUA 2POLA 4OVHA 4N94A 3L10A 4K3OA 3Q4JA 3BEPA 3D1GA 4K3KA 4MJPA 4K3LA 5AGVA 4PNVA 4K3RA 4OVFA 4S3IA 4N96A 5AH4A 3Q4KA 4N97A 4N95A 1MMIA 4TRTA 4K3QA 4TR8A 4RKIA 4TR7A 1JQLA 1OK7A 5FRQA 5FVEA 2AWAA 4K74A 4PNUA 3QSBB 3L0XA 4MJRA 4OVGA 3PWEA 2AVTA 4TSZA 3L0WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N9A A;  3D1F A;  4MJQ A;  5AH2 A;  1UNN A;  3T0P A;  4K3M A;  3PGE B;  4N99 A;  4K3P A;  3RB9 A;  3P16 A;  4TR6 A;  4PNW A;  3D1E A;  4N98 A;  1VPK A;  3F1V A;  1JQJ A;  3Q4L A;  3QSB A;  4K3S A;  2XUR A;  5AGU A;  2POL A;  4OVH A;  4N94 A;  3L10 A;  4K3O A;  3Q4J A;  3BEP A;  3D1G A;  4K3K A;  4MJP A;  4K3L A;  5AGV A;  4PNV A;  4K3R A;  4OVF A;  4S3I A;  4N96 A;  5AH4 A;  3Q4K A;  4N97 A;  4N95 A;  1MMI A;  4TRT A;  4K3Q A;  4TR8 A;  4RKI A;  4TR7 A;  1JQL A;  1OK7 A;  5FRQ A;  5FVE A;  2AWA A;  4K74 A;  4PNU A;  3QSB B;  3L0X A;  4MJR A;  4OVG A;  3PWE A;  2AVT A;  4TSZ A;  3L0W A; 
#chains in the Genus database with same CATH topology
 4N9A A;  3L10 B;  3D1F A;  4MJQ A;  5AH2 A;  1UNN A;  3T0P A;  4K3M A;  3PGE B;  4N99 A;  4K3P A;  3RB9 A;  3P16 A;  4TR6 A;  4PNW A;  3D1E A;  4N98 A;  1VPK A;  3F1V A;  1JQJ A;  3Q4L A;  3QSB A;  4K3S A;  2XUR A;  5AGU A;  2POL A;  4OVH A;  4N94 A;  3L10 A;  4K3O A;  3Q4J A;  3BEP A;  3D1G A;  4K3K A;  4MJP A;  4K3L A;  5AGV A;  4PNV A;  4K3R A;  3L0X B;  4OVF A;  4N96 A;  4S3I A;  5AH4 A;  3L0W B;  3PGE A;  3Q4K A;  4N97 A;  4N95 A;  1MMI A;  4TRT A;  4K3Q A;  4TR8 A;  4RKI A;  4TR7 A;  1JQL A;  1OK7 A;  5FRQ A;  5FVE A;  2AWA A;  4K74 A;  4PNU A;  3QSB B;  3L0X A;  4MJR A;  4OVG A;  3PWE A;  2AVT A;  4TSZ A;  3L0W A; 
#chains in the Genus database with same CATH homology
 4N9A A;  3D1F A;  4MJQ A;  5AH2 A;  1UNN A;  3T0P A;  4K3M A;  3PGE B;  4N99 A;  4K3P A;  3RB9 A;  3P16 A;  4TR6 A;  4PNW A;  3D1E A;  4N98 A;  1VPK A;  3F1V A;  1JQJ A;  3Q4L A;  3QSB A;  4K3S A;  2XUR A;  5AGU A;  2POL A;  4OVH A;  4N94 A;  3L10 A;  4K3O A;  3Q4J A;  3BEP A;  3D1G A;  4K3K A;  4MJP A;  4K3L A;  5AGV A;  4PNV A;  4K3R A;  4OVF A;  4S3I A;  4N96 A;  5AH4 A;  3Q4K A;  4N97 A;  4N95 A;  1MMI A;  4TRT A;  4K3Q A;  4TR8 A;  4RKI A;  4TR7 A;  1JQL A;  1OK7 A;  5FRQ A;  5FVE A;  2AWA A;  4K74 A;  4PNU A;  3QSB B;  3L0X A;  4MJR A;  4OVG A;  3PWE A;  2AVT A;  4TSZ A;  3L0W A; 
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similar chains in the Genus database (?% sequence similarity)
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