4OVHA

E. coli sliding clamp in complex with (r)-6-bromo-9-(2-(carboxymethylamino)-2-oxoethyl)-2,3,4,9-tetrahydro-1h-carbazole-2-carboxylic acid
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
364
structure length
362
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGGRLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Escherichia coli
molecule keywords DNA polymerase III subunit beta
total genus 89
structure length 362
sequence length 364
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2014-02-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovhA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovhA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovhA01
4K3OA 4MJPA 3D1FA 5AH4A 2AWAA 3QSBB 3QSBA 4K74A 4TR6A 4N99A 4S3IA 1MMIA 4OVGA 3PWEA 3F1VA 4PNWA 3Q4KA 5FVEA 4N94A 3D1GA 5AGVA 3RB9A 4OVFA 3T0PA 1OK7A 4K3KA 4N97A 4K3MA 4MJRA 3Q4LA 3P16A 2AVTA 5FRQA 4N96A 3Q4JA 3PGEB 4K3PA 4N98A 4K3LA 1JQLA 4RKIA 3L0XA 2XURA 4MJQA 5AH2A 1JQJA 4K3RA 1UNNA 3L10A 4PNUA 4K3QA 4TR8A 2POLA 4TR7A 4TRTA 3L0WA 4K3SA 4OVHA 3D1EA 4N9AA 4TSZA 5AGUA 3BEPA 1VPKA 4N95A 4PNVA
chains in the Genus database with same CATH superfamily
4K3OA 4MJPA 3D1FA 5AH4A 2AWAA 3QSBB 3QSBA 4K74A 4TR6A 4N99A 4S3IA 1MMIA 4OVGA 3PWEA 3F1VA 4PNWA 3Q4KA 5FVEA 4N94A 3D1GA 5AGVA 3RB9A 4OVFA 3T0PA 1OK7A 4K3KA 4N97A 4K3MA 4MJRA 3Q4LA 3P16A 3L0XB 2AVTA 5FRQA 4N96A 3Q4JA 3PGEB 4K3PA 4N98A 3L10B 1JQLA 4K3LA 4RKIA 3L0XA 2XURA 3L0WB 4MJQA 5AH2A 1JQJA 3PGEA 4K3RA 1UNNA 3L10A 4PNUA 4K3QA 4TR8A 2POLA 4TR7A 4TRTA 3L0WA 4K3SA 4OVHA 3D1EA 4N9AA 4TSZA 5AGUA 3BEPA 1VPKA 4N95A 4PNVA
chains in the Genus database with same CATH topology
4K3OA 4MJPA 3D1FA 5AH4A 2AWAA 3QSBB 3QSBA 4K74A 4TR6A 4N99A 4S3IA 1MMIA 4OVGA 3PWEA 3F1VA 4PNWA 3Q4KA 5FVEA 4N94A 3D1GA 5AGVA 3RB9A 4OVFA 3T0PA 1OK7A 4K3KA 4N97A 4K3MA 4MJRA 3Q4LA 3P16A 2AVTA 5FRQA 4N96A 3Q4JA 3PGEB 4K3PA 4N98A 4K3LA 1JQLA 4RKIA 3L0XA 2XURA 4MJQA 5AH2A 1JQJA 4K3RA 1UNNA 3L10A 4PNUA 4K3QA 4TR8A 2POLA 4TR7A 4TRTA 3L0WA 4K3SA 4OVHA 3D1EA 4N9AA 4TSZA 5AGUA 3BEPA 1VPKA 4N95A 4PNVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4K3O A;  4MJP A;  3D1F A;  5AH4 A;  2AWA A;  3QSB B;  3QSB A;  4K74 A;  4TR6 A;  4N99 A;  4S3I A;  1MMI A;  4OVG A;  3PWE A;  3F1V A;  4PNW A;  3Q4K A;  5FVE A;  4N94 A;  3D1G A;  5AGV A;  3RB9 A;  4OVF A;  3T0P A;  1OK7 A;  4K3K A;  4N97 A;  4K3M A;  4MJR A;  3Q4L A;  3P16 A;  2AVT A;  5FRQ A;  4N96 A;  3Q4J A;  3PGE B;  4K3P A;  4N98 A;  4K3L A;  1JQL A;  4RKI A;  3L0X A;  2XUR A;  4MJQ A;  5AH2 A;  1JQJ A;  4K3R A;  1UNN A;  3L10 A;  4PNU A;  4K3Q A;  4TR8 A;  2POL A;  4TR7 A;  4TRT A;  3L0W A;  4K3S A;  4OVH A;  3D1E A;  4N9A A;  4TSZ A;  5AGU A;  3BEP A;  1VPK A;  4N95 A;  4PNV A; 
#chains in the Genus database with same CATH topology
 4K3O A;  4MJP A;  3D1F A;  5AH4 A;  2AWA A;  3QSB B;  3QSB A;  4K74 A;  4TR6 A;  4N99 A;  4S3I A;  1MMI A;  4OVG A;  3PWE A;  3F1V A;  4PNW A;  3Q4K A;  5FVE A;  4N94 A;  3D1G A;  5AGV A;  3RB9 A;  4OVF A;  3T0P A;  1OK7 A;  4K3K A;  4N97 A;  4K3M A;  4MJR A;  3Q4L A;  3P16 A;  3L0X B;  2AVT A;  5FRQ A;  4N96 A;  3Q4J A;  3PGE B;  4K3P A;  4N98 A;  3L10 B;  1JQL A;  4K3L A;  4RKI A;  3L0X A;  2XUR A;  3L0W B;  4MJQ A;  5AH2 A;  1JQJ A;  3PGE A;  4K3R A;  1UNN A;  3L10 A;  4PNU A;  4K3Q A;  4TR8 A;  2POL A;  4TR7 A;  4TRT A;  3L0W A;  4K3S A;  4OVH A;  3D1E A;  4N9A A;  4TSZ A;  5AGU A;  3BEP A;  1VPK A;  4N95 A;  4PNV A; 
#chains in the Genus database with same CATH homology
 4K3O A;  4MJP A;  3D1F A;  5AH4 A;  2AWA A;  3QSB B;  3QSB A;  4K74 A;  4TR6 A;  4N99 A;  4S3I A;  1MMI A;  4OVG A;  3PWE A;  3F1V A;  4PNW A;  3Q4K A;  5FVE A;  4N94 A;  3D1G A;  5AGV A;  3RB9 A;  4OVF A;  3T0P A;  1OK7 A;  4K3K A;  4N97 A;  4K3M A;  4MJR A;  3Q4L A;  3P16 A;  2AVT A;  5FRQ A;  4N96 A;  3Q4J A;  3PGE B;  4K3P A;  4N98 A;  4K3L A;  1JQL A;  4RKI A;  3L0X A;  2XUR A;  4MJQ A;  5AH2 A;  1JQJ A;  4K3R A;  1UNN A;  3L10 A;  4PNU A;  4K3Q A;  4TR8 A;  2POL A;  4TR7 A;  4TRT A;  3L0W A;  4K3S A;  4OVH A;  3D1E A;  4N9A A;  4TSZ A;  5AGU A;  3BEP A;  1VPK A;  4N95 A;  4PNV A; 
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similar chains in the Genus database (?% sequence similarity)
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