4OVHA

E. coli sliding clamp in complex with (r)-6-bromo-9-(2-(carboxymethylamino)-2-oxoethyl)-2,3,4,9-tetrahydro-1h-carbazole-2-carboxylic acid
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
364
structure length
362
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGGRLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Escherichia coli
molecule keywords DNA polymerase III subunit beta
total genus 89
structure length 362
sequence length 364
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2014-02-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovhA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovhA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4ovhA01
4K3LA 4MJPA 1OK7A 4PNWA 4K3QA 4PNUA 4PNVA 4RKIA 4K3SA 4TRTA 3Q4JA 4N96A 4OVHA 3RB9A 4K3MA 3L10A 4N9AA 4OVGA 3Q4LA 4TR6A 4TR8A 1MMIA 4N94A 5AGUA 3T0PA 5FVEA 2AWAA 2AVTA 5FRQA 4N98A 3P16A 2POLA 3L0WA 3L0XA 3PGEB 1JQJA 3D1EA 3D1FA 4TR7A 5AH4A 4S3IA 1VPKA 4TSZA 3BEPA 3QSBA 4K3KA 3QSBB 1JQLA 4K3OA 3D1GA 4K74A 5AH2A 4K3RA 2XURA 4N95A 1UNNA 3F1VA 4K3PA 4N99A 5AGVA 4N97A 4MJRA 4MJQA 3Q4KA 4OVFA 3PWEA
chains in the Genus database with same CATH superfamily
4K3LA 4MJPA 1OK7A 4PNWA 4K3QA 4PNUA 4PNVA 4RKIA 4K3SA 4TRTA 3Q4JA 4N96A 4OVHA 3RB9A 4K3MA 3L10A 4N9AA 4OVGA 3Q4LA 4TR6A 4TR8A 1MMIA 3L10B 4N94A 5AGUA 5FVEA 2AWAA 2AVTA 3T0PA 5FRQA 4N98A 3PGEA 2POLA 3P16A 3L0WA 3L0XA 3PGEB 1JQJA 3D1EA 3L0XB 3D1FA 4TR7A 5AH4A 3L0WB 4S3IA 1VPKA 4TSZA 3BEPA 3QSBA 4K3KA 3QSBB 1JQLA 4K3OA 3D1GA 4K74A 5AH2A 4K3RA 2XURA 4N95A 1UNNA 3F1VA 4K3PA 4N99A 5AGVA 4N97A 4MJRA 4MJQA 3Q4KA 4OVFA 3PWEA
chains in the Genus database with same CATH topology
4K3LA 4MJPA 1OK7A 4PNWA 4K3QA 4PNUA 4PNVA 4RKIA 4K3SA 4TRTA 3Q4JA 4N96A 4OVHA 3RB9A 4K3MA 3L10A 4N9AA 4OVGA 3Q4LA 4TR6A 4TR8A 1MMIA 4N94A 5AGUA 3T0PA 5FVEA 2AWAA 2AVTA 5FRQA 4N98A 3P16A 2POLA 3L0WA 3L0XA 3PGEB 1JQJA 3D1EA 3D1FA 4TR7A 5AH4A 4S3IA 1VPKA 4TSZA 3BEPA 3QSBA 4K3KA 3QSBB 1JQLA 4K3OA 3D1GA 4K74A 5AH2A 4K3RA 2XURA 4N95A 1UNNA 3F1VA 4K3PA 4N99A 5AGVA 4N97A 4MJRA 4MJQA 3Q4KA 4OVFA 3PWEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4K3L A;  4MJP A;  1OK7 A;  4PNW A;  4K3Q A;  4PNU A;  4PNV A;  4RKI A;  4K3S A;  4TRT A;  3Q4J A;  4N96 A;  4OVH A;  3RB9 A;  4K3M A;  3L10 A;  4N9A A;  4OVG A;  3Q4L A;  4TR6 A;  4TR8 A;  1MMI A;  4N94 A;  5AGU A;  3T0P A;  5FVE A;  2AWA A;  2AVT A;  5FRQ A;  4N98 A;  3P16 A;  2POL A;  3L0W A;  3L0X A;  3PGE B;  1JQJ A;  3D1E A;  3D1F A;  4TR7 A;  5AH4 A;  4S3I A;  1VPK A;  4TSZ A;  3BEP A;  3QSB A;  4K3K A;  3QSB B;  1JQL A;  4K3O A;  3D1G A;  4K74 A;  5AH2 A;  4K3R A;  2XUR A;  4N95 A;  1UNN A;  3F1V A;  4K3P A;  4N99 A;  5AGV A;  4N97 A;  4MJR A;  4MJQ A;  3Q4K A;  4OVF A;  3PWE A; 
#chains in the Genus database with same CATH topology
 4K3L A;  4MJP A;  1OK7 A;  4PNW A;  4K3Q A;  4PNU A;  4PNV A;  4RKI A;  4K3S A;  4TRT A;  3Q4J A;  4N96 A;  4OVH A;  3RB9 A;  4K3M A;  3L10 A;  4N9A A;  4OVG A;  3Q4L A;  4TR6 A;  4TR8 A;  1MMI A;  3L10 B;  4N94 A;  5AGU A;  5FVE A;  2AWA A;  2AVT A;  3T0P A;  5FRQ A;  4N98 A;  3PGE A;  2POL A;  3P16 A;  3L0W A;  3L0X A;  3PGE B;  1JQJ A;  3D1E A;  3L0X B;  3D1F A;  4TR7 A;  5AH4 A;  3L0W B;  4S3I A;  1VPK A;  4TSZ A;  3BEP A;  3QSB A;  4K3K A;  3QSB B;  1JQL A;  4K3O A;  3D1G A;  4K74 A;  5AH2 A;  4K3R A;  2XUR A;  4N95 A;  1UNN A;  3F1V A;  4K3P A;  4N99 A;  5AGV A;  4N97 A;  4MJR A;  4MJQ A;  3Q4K A;  4OVF A;  3PWE A; 
#chains in the Genus database with same CATH homology
 4K3L A;  4MJP A;  1OK7 A;  4PNW A;  4K3Q A;  4PNU A;  4PNV A;  4RKI A;  4K3S A;  4TRT A;  3Q4J A;  4N96 A;  4OVH A;  3RB9 A;  4K3M A;  3L10 A;  4N9A A;  4OVG A;  3Q4L A;  4TR6 A;  4TR8 A;  1MMI A;  4N94 A;  5AGU A;  3T0P A;  5FVE A;  2AWA A;  2AVT A;  5FRQ A;  4N98 A;  3P16 A;  2POL A;  3L0W A;  3L0X A;  3PGE B;  1JQJ A;  3D1E A;  3D1F A;  4TR7 A;  5AH4 A;  4S3I A;  1VPK A;  4TSZ A;  3BEP A;  3QSB A;  4K3K A;  3QSB B;  1JQL A;  4K3O A;  3D1G A;  4K74 A;  5AH2 A;  4K3R A;  2XUR A;  4N95 A;  1UNN A;  3F1V A;  4K3P A;  4N99 A;  5AGV A;  4N97 A;  4MJR A;  4MJQ A;  3Q4K A;  4OVF A;  3PWE A; 
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similar chains in the Genus database (?% sequence similarity)
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