4P39A

Crystal structure of the human c5ar antagonist c5a-a8
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
69
structure length
69
Chain Sequence
STLQKKIEEIAAKYKHSVVKKCCYDGARVNNDETCEQRAARISLGPRCIKAFTECCVVASQLRANISFK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and functional characterization of human and murine C5a anaphylatoxins.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Complement C5
total genus 23
structure length 69
sequence length 69
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-03-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01821 ANATO Anaphylotoxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.91.20 Mainly Alpha Up-down Bundle Influenza Virus Matrix Protein; Chain A, domain 1 Anaphylotoxins (complement system) 4p39A00
4P3AA 1CFAA 4P3BA 4FXKB 4WB2A 4HW5A 1KJSA 4UU9C 2B39A 3HQAA 4I6OA 5JPNB 1C5AA 4HWJA 2A73B 4P39A 4WB3A 3HQBA 3KLSA 5B4PB 3CU7A
chains in the Genus database with same CATH superfamily
4P3AA 5JPMB 4PUSA 1CFAA 2Z16A 1EA3A 5CQEA 3MD2A 4P3BA 4FXKB 4WB2A 3VDXA 4HW5A 1KJSA 4UU9C 2B39A 3HQAA 4I6OA 5JPNB 1C5AA 4IQ4A 4HWJA 2A73B 4P39A 4FXGB 4WB3A 3HQBA 1AA7A 4ITVA 3KLSA 4D9JA 5B4PB 3CU7A
chains in the Genus database with same CATH topology
4P3AA 1CFAA 4P3BA 4FXKB 4WB2A 4HW5A 1KJSA 4UU9C 2B39A 3HQAA 4I6OA 5JPNB 1C5AA 4HWJA 2A73B 4P39A 4WB3A 3HQBA 3KLSA 5B4PB 3CU7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P3A A;  1CFA A;  4P3B A;  4FXK B;  4WB2 A;  4HW5 A;  1KJS A;  4UU9 C;  2B39 A;  3HQA A;  4I6O A;  5JPN B;  1C5A A;  4HWJ A;  2A73 B;  4P39 A;  4WB3 A;  3HQB A;  3KLS A;  5B4P B;  3CU7 A; 
#chains in the Genus database with same CATH topology
 4P3A A;  5JPM B;  4PUS A;  1CFA A;  2Z16 A;  1EA3 A;  5CQE A;  3MD2 A;  4P3B A;  4FXK B;  4WB2 A;  3VDX A;  4HW5 A;  1KJS A;  4UU9 C;  2B39 A;  3HQA A;  4I6O A;  5JPN B;  1C5A A;  4IQ4 A;  4HWJ A;  2A73 B;  4P39 A;  4FXG B;  4WB3 A;  3HQB A;  1AA7 A;  4ITV A;  3KLS A;  4D9J A;  5B4P B;  3CU7 A; 
#chains in the Genus database with same CATH homology
 4P3A A;  1CFA A;  4P3B A;  4FXK B;  4WB2 A;  4HW5 A;  1KJS A;  4UU9 C;  2B39 A;  3HQA A;  4I6O A;  5JPN B;  1C5A A;  4HWJ A;  2A73 B;  4P39 A;  4WB3 A;  3HQB A;  3KLS A;  5B4P B;  3CU7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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