4P39A

Crystal structure of the human c5ar antagonist c5a-a8
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
69
structure length
69
Chain Sequence
STLQKKIEEIAAKYKHSVVKKCCYDGARVNNDETCEQRAARISLGPRCIKAFTECCVVASQLRANISFK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and functional characterization of human and murine C5a anaphylatoxins.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Complement C5
total genus 23
structure length 69
sequence length 69
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-03-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01821 ANATO Anaphylotoxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.91.20 Mainly Alpha Up-down Bundle Influenza Virus Matrix Protein; Chain A, domain 1 Anaphylotoxins (complement system) 4p39A00
2B39A 2A73B 3HQBA 5JPNB 1C5AA 4I6OA 3KLSA 1KJSA 1CFAA 4P39A 4WB3A 4P3BA 4HWJA 4UU9C 4HW5A 4P3AA 5B4PB 4FXKB 3CU7A 3HQAA 4WB2A
chains in the Genus database with same CATH superfamily
1AA7A 2B39A 2A73B 3HQBA 4FXGB 3VDXA 5JPNB 5JPMB 5CQEA 1C5AA 4I6OA 4IQ4A 3KLSA 1KJSA 3MD2A 1CFAA 4P39A 4WB3A 4P3BA 4HWJA 2Z16A 1EA3A 4D9JA 4UU9C 4HW5A 4P3AA 4PUSA 5B4PB 4FXKB 3CU7A 3HQAA 4WB2A 4ITVA
chains in the Genus database with same CATH topology
2B39A 2A73B 3HQBA 5JPNB 1C5AA 4I6OA 3KLSA 1KJSA 1CFAA 4P39A 4WB3A 4P3BA 4HWJA 4UU9C 4HW5A 4P3AA 5B4PB 4FXKB 3CU7A 3HQAA 4WB2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B39 A;  2A73 B;  3HQB A;  5JPN B;  1C5A A;  4I6O A;  3KLS A;  1KJS A;  1CFA A;  4P39 A;  4WB3 A;  4P3B A;  4HWJ A;  4UU9 C;  4HW5 A;  4P3A A;  5B4P B;  4FXK B;  3CU7 A;  3HQA A;  4WB2 A; 
#chains in the Genus database with same CATH topology
 1AA7 A;  2B39 A;  2A73 B;  3HQB A;  4FXG B;  3VDX A;  5JPN B;  5JPM B;  5CQE A;  1C5A A;  4I6O A;  4IQ4 A;  3KLS A;  1KJS A;  3MD2 A;  1CFA A;  4P39 A;  4WB3 A;  4P3B A;  4HWJ A;  2Z16 A;  1EA3 A;  4D9J A;  4UU9 C;  4HW5 A;  4P3A A;  4PUS A;  5B4P B;  4FXK B;  3CU7 A;  3HQA A;  4WB2 A;  4ITV A; 
#chains in the Genus database with same CATH homology
 2B39 A;  2A73 B;  3HQB A;  5JPN B;  1C5A A;  4I6O A;  3KLS A;  1KJS A;  1CFA A;  4P39 A;  4WB3 A;  4P3B A;  4HWJ A;  4UU9 C;  4HW5 A;  4P3A A;  5B4P B;  4FXK B;  3CU7 A;  3HQA A;  4WB2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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