4P39 | Genus

Total Genus 23

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	23
sequence length	69
structure length	69
Chain Sequence	STLQKKIEEIAAKYKHSVVKKCCYDGARVNNDETCEQRAARISLGPRCIKAFTECCVVASQLRANISFK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Immune system
source organism	Homo sapiens
publication title	Structural and functional characterization of human and murine C5a anaphylatoxins. pubmed doi rcsb
molecule keywords	Complement C5
total genus	23
structure length	69
sequence length	69
chains with identical sequence	B, C, D
ec nomenclature
pdb deposition date	2014-03-06

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01821	ANATO	Anaphylotoxin-like domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.91.20	Mainly Alpha	Up-down Bundle	Influenza Virus Matrix Protein; Chain A, domain 1	Anaphylotoxins (complement system)	4p39A00

1CFAA 4FXKB 4HWJA 1C5AA 4UU9C 4WB3A 2A73B 4I6OA 3CU7A 5B4PB 4HW5A 4P3AA 3KLSA 5JPNB 1KJSA 3HQAA 4P3BA 4P39A 4WB2A 2B39A 3HQBA
chains in the Genus database with same CATH superfamily

1CFAA 4FXGB 3MD2A 4FXKB 4HWJA 1C5AA 4UU9C 4WB3A 2A73B 4I6OA 1AA7A 3CU7A 5B4PB 4ITVA 4IQ4A 4HW5A 4P3AA 2Z16A 4D9JA 3KLSA 3VDXA 5JPNB 5JPMB 1KJSA 1EA3A 3HQAA 5CQEA 4P3BA 4P39A 4WB2A 2B39A 4PUSA 3HQBA
chains in the Genus database with same CATH topology

1CFAA 4FXKB 4HWJA 1C5AA 4UU9C 4WB3A 2A73B 4I6OA 3CU7A 5B4PB 4HW5A 4P3AA 3KLSA 5JPNB 1KJSA 3HQAA 4P3BA 4P39A 4WB2A 2B39A 3HQBA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1CFA A;  4FXK B;  4HWJ A;  1C5A A;  4UU9 C;  4WB3 A;  2A73 B;  4I6O A;  3CU7 A;  5B4P B;  4HW5 A;  4P3A A;  3KLS A;  5JPN B;  1KJS A;  3HQA A;  4P3B A;  4P39 A;  4WB2 A;  2B39 A;  3HQB A; 
#chains in the Genus database with same CATH topology
 1CFA A;  4FXG B;  3MD2 A;  4FXK B;  4HWJ A;  1C5A A;  4UU9 C;  4WB3 A;  2A73 B;  4I6O A;  1AA7 A;  3CU7 A;  5B4P B;  4ITV A;  4IQ4 A;  4HW5 A;  4P3A A;  2Z16 A;  4D9J A;  3KLS A;  3VDX A;  5JPN B;  5JPM B;  1KJS A;  1EA3 A;  3HQA A;  5CQE A;  4P3B A;  4P39 A;  4WB2 A;  2B39 A;  4PUS A;  3HQB A; 
#chains in the Genus database with same CATH homology
 1CFA A;  4FXK B;  4HWJ A;  1C5A A;  4UU9 C;  4WB3 A;  2A73 B;  4I6O A;  3CU7 A;  5B4P B;  4HW5 A;  4P3A A;  3KLS A;  5JPN B;  1KJS A;  3HQA A;  4P3B A;  4P39 A;  4WB2 A;  2B39 A;  3HQB A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4P39A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations