4P3AA

Crystal structure of the mouse c5a anaphylatoxin
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
70
structure length
70
Chain Sequence
GANLHLLRQKIEEQAAKYKHSVPKKCCYDGARVNFYETCEERVARVTIGPLCIRAFNECCTIANKIRKES
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and functional characterization of human and murine C5a anaphylatoxins.
pubmed doi rcsb
molecule tags Immune system
source organism Mus musculus
molecule keywords Complement C5
total genus 25
structure length 70
sequence length 70
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-03-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01821 ANATO Anaphylotoxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.91.20 Mainly Alpha Up-down Bundle Influenza Virus Matrix Protein; Chain A, domain 1 Anaphylotoxins (complement system) 4p3aA00
4HW5A 5JPNB 5B4PB 3KLSA 2B39A 4P3AA 2A73B 4I6OA 4WB3A 1C5AA 4FXKB 4WB2A 4P39A 4P3BA 3CU7A 4UU9C 1KJSA 1CFAA 3HQBA 3HQAA 4HWJA
chains in the Genus database with same CATH superfamily
4HW5A 5JPNB 4IQ4A 5B4PB 4FXGB 4PUSA 3KLSA 2B39A 4P3AA 1EA3A 3VDXA 2A73B 3MD2A 4I6OA 4WB3A 1C5AA 4FXKB 4ITVA 4WB2A 2Z16A 4D9JA 4P39A 4P3BA 1AA7A 3CU7A 4UU9C 1KJSA 5JPMB 1CFAA 5CQEA 3HQBA 3HQAA 4HWJA
chains in the Genus database with same CATH topology
4HW5A 5JPNB 5B4PB 3KLSA 2B39A 4P3AA 2A73B 4I6OA 4WB3A 1C5AA 4FXKB 4WB2A 4P39A 4P3BA 3CU7A 4UU9C 1KJSA 1CFAA 3HQBA 3HQAA 4HWJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HW5 A;  5JPN B;  5B4P B;  3KLS A;  2B39 A;  4P3A A;  2A73 B;  4I6O A;  4WB3 A;  1C5A A;  4FXK B;  4WB2 A;  4P39 A;  4P3B A;  3CU7 A;  4UU9 C;  1KJS A;  1CFA A;  3HQB A;  3HQA A;  4HWJ A; 
#chains in the Genus database with same CATH topology
 4HW5 A;  5JPN B;  4IQ4 A;  5B4P B;  4FXG B;  4PUS A;  3KLS A;  2B39 A;  4P3A A;  1EA3 A;  3VDX A;  2A73 B;  3MD2 A;  4I6O A;  4WB3 A;  1C5A A;  4FXK B;  4ITV A;  4WB2 A;  2Z16 A;  4D9J A;  4P39 A;  4P3B A;  1AA7 A;  3CU7 A;  4UU9 C;  1KJS A;  5JPM B;  1CFA A;  5CQE A;  3HQB A;  3HQA A;  4HWJ A; 
#chains in the Genus database with same CATH homology
 4HW5 A;  5JPN B;  5B4P B;  3KLS A;  2B39 A;  4P3A A;  2A73 B;  4I6O A;  4WB3 A;  1C5A A;  4FXK B;  4WB2 A;  4P39 A;  4P3B A;  3CU7 A;  4UU9 C;  1KJS A;  1CFA A;  3HQB A;  3HQA A;  4HWJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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