4RT4A

Crystal structure of dpy30 complexed with bre2
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
50
structure length
50
Chain Sequence
DLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural implications of Dpy30 oligomerization for MLL/SET1 COMPASS H3K4 trimethylation
pubmed doi rcsb
molecule keywords Protein dpy-30 homolog
molecule tags Protein binding
source organism Homo sapiens
total genus 15
structure length 50
sequence length 50
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05186 Dpy-30 Dpy-30 motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 4rt4A00
4ZP3A 2KYGA 2DRNA 3IM3A 5HVZA 3G36A 4RTAA 2H9RA 3IM4A 4RIQA 2IZYA 4RT4A 1R2AA 1L6EA 2EZWA 4F9KA
chains in the Genus database with same CATH superfamily
4ZP3A 3S4BA 3S4AA 2CB9A 2CQSA 1L6EA 3GWHA 3AFJA 2DRNA 3UFEA 3G36A 2CBGA 3QFYA 2OUTA 4RTAA 2H9RA 3IM4A 4RIQA 3S4CA 2RQYA 2K9QA 3IM3A 3QFZA 3QDEA 3PMIA 2KNGA 3RRSA 4F9KA 4RT4A 1R2AA 2EZWA 3S4DA 2KYGA 3QG0A 3RSYA 3ACSA 5HVZA 2I15A 3ACTA 2CQTA 2IZYA
chains in the Genus database with same CATH topology
4ZP3A 2KYGA 2DRNA 3IM3A 5HVZA 3G36A 4RTAA 2H9RA 3IM4A 4RIQA 2IZYA 4RT4A 1R2AA 1L6EA 2EZWA 4F9KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZP3 A;  2KYG A;  2DRN A;  3IM3 A;  5HVZ A;  3G36 A;  4RTA A;  2H9R A;  3IM4 A;  4RIQ A;  2IZY A;  4RT4 A;  1R2A A;  1L6E A;  2EZW A;  4F9K A; 
#chains in the Genus database with same CATH topology
 4ZP3 A;  3S4B A;  3S4A A;  2CB9 A;  2CQS A;  1L6E A;  3GWH A;  3AFJ A;  2DRN A;  3UFE A;  3G36 A;  2CBG A;  3QFY A;  2OUT A;  4RTA A;  2H9R A;  3IM4 A;  4RIQ A;  3S4C A;  2RQY A;  2K9Q A;  3IM3 A;  3QFZ A;  3QDE A;  3PMI A;  2KNG A;  3RRS A;  4F9K A;  4RT4 A;  1R2A A;  2EZW A;  3S4D A;  2KYG A;  3QG0 A;  3RSY A;  3ACS A;  5HVZ A;  2I15 A;  3ACT A;  2CQT A;  2IZY A; 
#chains in the Genus database with same CATH homology
 4ZP3 A;  2KYG A;  2DRN A;  3IM3 A;  5HVZ A;  3G36 A;  4RTA A;  2H9R A;  3IM4 A;  4RIQ A;  2IZY A;  4RT4 A;  1R2A A;  1L6E A;  2EZW A;  4F9K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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