4RT4A

Crystal structure of dpy30 complexed with bre2
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
50
structure length
50
Chain Sequence
DLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural implications of Dpy30 oligomerization for MLL/SET1 COMPASS H3K4 trimethylation
pubmed doi rcsb
molecule keywords Protein dpy-30 homolog
molecule tags Protein binding
source organism Homo sapiens
total genus 15
structure length 50
sequence length 50
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05186 Dpy-30 Dpy-30 motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 4rt4A00
4RIQA 4RT4A 2KYGA 3G36A 2H9RA 3IM4A 4ZP3A 2DRNA 3IM3A 1L6EA 1R2AA 2EZWA 4RTAA 2IZYA 4F9KA 5HVZA
chains in the Genus database with same CATH superfamily
4RT4A 2KYGA 3S4DA 3S4AA 3S4BA 3ACSA 2CBGA 3IM3A 3ACTA 3UFEA 4RTAA 4F9KA 4RIQA 2RQYA 3G36A 2H9RA 4ZP3A 2CQTA 3QDEA 3S4CA 2I15A 2IZYA 3AFJA 2OUTA 3QG0A 2DRNA 1R2AA 3RSYA 2CB9A 2K9QA 3GWHA 2CQSA 2KNGA 3IM4A 3PMIA 3QFYA 3QFZA 1L6EA 2EZWA 3RRSA 5HVZA
chains in the Genus database with same CATH topology
4RIQA 4RT4A 2KYGA 3G36A 2H9RA 3IM4A 4ZP3A 2DRNA 3IM3A 1L6EA 1R2AA 2EZWA 4RTAA 2IZYA 4F9KA 5HVZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RIQ A;  4RT4 A;  2KYG A;  3G36 A;  2H9R A;  3IM4 A;  4ZP3 A;  2DRN A;  3IM3 A;  1L6E A;  1R2A A;  2EZW A;  4RTA A;  2IZY A;  4F9K A;  5HVZ A; 
#chains in the Genus database with same CATH topology
 4RT4 A;  2KYG A;  3S4D A;  3S4A A;  3S4B A;  3ACS A;  2CBG A;  3IM3 A;  3ACT A;  3UFE A;  4RTA A;  4F9K A;  4RIQ A;  2RQY A;  3G36 A;  2H9R A;  4ZP3 A;  2CQT A;  3QDE A;  3S4C A;  2I15 A;  2IZY A;  3AFJ A;  2OUT A;  3QG0 A;  2DRN A;  1R2A A;  3RSY A;  2CB9 A;  2K9Q A;  3GWH A;  2CQS A;  2KNG A;  3IM4 A;  3PMI A;  3QFY A;  3QFZ A;  1L6E A;  2EZW A;  3RRS A;  5HVZ A; 
#chains in the Genus database with same CATH homology
 4RIQ A;  4RT4 A;  2KYG A;  3G36 A;  2H9R A;  3IM4 A;  4ZP3 A;  2DRN A;  3IM3 A;  1L6E A;  1R2A A;  2EZW A;  4RTA A;  2IZY A;  4F9K A;  5HVZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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