4S3IA

Crystal structure of beta clamp from helicobacter pylori
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
374
structure length
374
Chain Sequence
MKISVSKNDLENALRYLQAFLDKKDASSIASHIHLEVIKEKLFLKASDSDIGLKSYIFTQSSDKEGVGTINGKKFLDIISCLKDSNIILETKDDSLAIKQNKSSFKLPMFDADEFPEFPVIDPKVSIEVNAPFLVDAFKKIAPVIEQTSHKRELAGILMQFDQKHQTLSVVGTDTKRLSYTQLEKISIHSTEEDISCILPKRALLEILKLFYENFSFKSDGMLAVIENEMHTFFTKLIDGNYPDYQKILPKEYISSFTLGKEEFKESIKLCSSLSSTIKLTLEKNNALFESLDSEHSETAKTSVEIEKGLDIEKAFHLGVNAKFFLEALNALGTTQFVLRCNEPSSPFLIQESLDEKQSHLNAKISTLMMPITL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into beta-Clamp and its interaction with DNA Ligase in Helicobacter pylori.
pubmed doi rcsb
molecule tags Transferase
source organism Helicobacter pylori 26695
molecule keywords DNA polymerase III subunit beta
total genus 88
structure length 374
sequence length 374
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2015-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4s3iA02
4OVHA 3L0XA 3D1FA 3Q4JA 3F1VA 4OVGA 4TR8A 4S3IA 4N96A 4RKIA 4TSZA 2XURA 3T0PA 4K3LA 3PGEB 3Q4KA 4K3KA 4N98A 4K3QA 2AWAA 3L10A 1JQLA 1VPKA 2AVTA 4N95A 1UNNA 4K3RA 4K74A 3QSBB 4MJPA 3Q4LA 4N94A 4PNWA 3QSBA 4N9AA 5AGUA 5AH4A 4PNUA 4K3OA 1MMIA 4PNVA 4N99A 4OVFA 4TR7A 3L0WA 5FVEA 3D1GA 5AH2A 1OK7A 2POLA 4K3MA 4TRTA 1JQJA 4N97A 4MJQA 3PWEA 4K3SA 5AGVA 5FRQA 3RB9A 3BEPA 4MJRA 3D1EA 4TR6A 3P16A 4K3PA
chains in the Genus database with same CATH superfamily
4OVHA 3L0XA 3D1FA 3Q4JA 3F1VA 4OVGA 4TR8A 4S3IA 4N96A 4RKIA 4TSZA 2XURA 3T0PA 4K3LA 3PGEB 3Q4KA 4K3KA 4N98A 3PGEA 3L10B 4K3QA 2AWAA 3L10A 1JQLA 1VPKA 2AVTA 4N95A 1UNNA 4K3RA 4K74A 3QSBB 4MJPA 3Q4LA 4N94A 4PNWA 3QSBA 4N9AA 5AGUA 5AH4A 4PNUA 4K3OA 1MMIA 4PNVA 4N99A 4OVFA 3L0WB 4TR7A 3L0WA 5FVEA 3D1GA 5AH2A 1OK7A 2POLA 4K3MA 4TRTA 1JQJA 4N97A 4MJQA 3PWEA 4K3SA 5AGVA 5FRQA 3RB9A 3BEPA 4MJRA 3D1EA 4TR6A 3P16A 4K3PA 3L0XB
chains in the Genus database with same CATH topology
4OVHA 3L0XA 3D1FA 3Q4JA 3F1VA 4OVGA 4TR8A 4S3IA 4N96A 4RKIA 4TSZA 2XURA 3T0PA 4K3LA 3PGEB 3Q4KA 4K3KA 4N98A 4K3QA 2AWAA 3L10A 1JQLA 1VPKA 2AVTA 4N95A 1UNNA 4K3RA 4K74A 3QSBB 4MJPA 3Q4LA 4N94A 4PNWA 3QSBA 4N9AA 5AGUA 5AH4A 4PNUA 4K3OA 1MMIA 4PNVA 4N99A 4OVFA 4TR7A 3L0WA 5FVEA 3D1GA 5AH2A 1OK7A 2POLA 4K3MA 4TRTA 1JQJA 4N97A 4MJQA 3PWEA 4K3SA 5AGVA 5FRQA 3RB9A 3BEPA 4MJRA 3D1EA 4TR6A 3P16A 4K3PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OVH A;  3L0X A;  3D1F A;  3Q4J A;  3F1V A;  4OVG A;  4TR8 A;  4S3I A;  4N96 A;  4RKI A;  4TSZ A;  2XUR A;  3T0P A;  4K3L A;  3PGE B;  3Q4K A;  4K3K A;  4N98 A;  4K3Q A;  2AWA A;  3L10 A;  1JQL A;  1VPK A;  2AVT A;  4N95 A;  1UNN A;  4K3R A;  4K74 A;  3QSB B;  4MJP A;  3Q4L A;  4N94 A;  4PNW A;  3QSB A;  4N9A A;  5AGU A;  5AH4 A;  4PNU A;  4K3O A;  1MMI A;  4PNV A;  4N99 A;  4OVF A;  4TR7 A;  3L0W A;  5FVE A;  3D1G A;  5AH2 A;  1OK7 A;  2POL A;  4K3M A;  4TRT A;  1JQJ A;  4N97 A;  4MJQ A;  3PWE A;  4K3S A;  5AGV A;  5FRQ A;  3RB9 A;  3BEP A;  4MJR A;  3D1E A;  4TR6 A;  3P16 A;  4K3P A; 
#chains in the Genus database with same CATH topology
 4OVH A;  3L0X A;  3D1F A;  3Q4J A;  3F1V A;  4OVG A;  4TR8 A;  4S3I A;  4N96 A;  4RKI A;  4TSZ A;  2XUR A;  3T0P A;  4K3L A;  3PGE B;  3Q4K A;  4K3K A;  4N98 A;  3PGE A;  3L10 B;  4K3Q A;  2AWA A;  3L10 A;  1JQL A;  1VPK A;  2AVT A;  4N95 A;  1UNN A;  4K3R A;  4K74 A;  3QSB B;  4MJP A;  3Q4L A;  4N94 A;  4PNW A;  3QSB A;  4N9A A;  5AGU A;  5AH4 A;  4PNU A;  4K3O A;  1MMI A;  4PNV A;  4N99 A;  4OVF A;  3L0W B;  4TR7 A;  3L0W A;  5FVE A;  3D1G A;  5AH2 A;  1OK7 A;  2POL A;  4K3M A;  4TRT A;  1JQJ A;  4N97 A;  4MJQ A;  3PWE A;  4K3S A;  5AGV A;  5FRQ A;  3RB9 A;  3BEP A;  4MJR A;  3D1E A;  4TR6 A;  3P16 A;  4K3P A;  3L0X B; 
#chains in the Genus database with same CATH homology
 4OVH A;  3L0X A;  3D1F A;  3Q4J A;  3F1V A;  4OVG A;  4TR8 A;  4S3I A;  4N96 A;  4RKI A;  4TSZ A;  2XUR A;  3T0P A;  4K3L A;  3PGE B;  3Q4K A;  4K3K A;  4N98 A;  4K3Q A;  2AWA A;  3L10 A;  1JQL A;  1VPK A;  2AVT A;  4N95 A;  1UNN A;  4K3R A;  4K74 A;  3QSB B;  4MJP A;  3Q4L A;  4N94 A;  4PNW A;  3QSB A;  4N9A A;  5AGU A;  5AH4 A;  4PNU A;  4K3O A;  1MMI A;  4PNV A;  4N99 A;  4OVF A;  4TR7 A;  3L0W A;  5FVE A;  3D1G A;  5AH2 A;  1OK7 A;  2POL A;  4K3M A;  4TRT A;  1JQJ A;  4N97 A;  4MJQ A;  3PWE A;  4K3S A;  5AGV A;  5FRQ A;  3RB9 A;  3BEP A;  4MJR A;  3D1E A;  4TR6 A;  3P16 A;  4K3P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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