4TR7A

Crystal structure of dna polymerase sliding clamp from mycobaterium tuberculosis
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
391
structure length
375
Chain Sequence
GLTDLTFRLLRESFADAVSWVAKNPVLSGVLLTGSDNGLTISGFDYEVSEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASPDIEAAVLVPAKTLAEAAKAGGGSDVRLSLGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDRPVAGLNGNGPFPAVSTDYVYLLMPVR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Mycobacterium tuberculosis
molecule keywords DNA polymerase III subunit beta
total genus 81
structure length 375
sequence length 391
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2014-06-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4tr7A01
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4tr7A02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4tr7A03
3L10A 4K3LA 3PGEB 4N94A 4K3QA 4N98A 3BEPA 3D1GA 4N9AA 3L0WA 4RKIA 4OVFA 4S3IA 1MMIA 4TRTA 5FVEA 4PNVA 3RB9A 4K3MA 4TSZA 3D1EA 4MJPA 3Q4JA 4OVGA 5AH2A 4N99A 5AGUA 4TR7A 4MJRA 4OVHA 4K3KA 4TR8A 5AH4A 1UNNA 4K3PA 1JQJA 2POLA 4K3RA 4N97A 4N95A 3L0XA 5FRQA 4TR6A 3T0PA 1VPKA 3PWEA 3Q4LA 4K3OA 3P16A 3QSBA 3Q4KA 1JQLA 1OK7A 4N96A 3F1VA 2AWAA 3D1FA 3QSBB 5AGVA 2AVTA 4K74A 4MJQA 4PNUA 2XURA 4PNWA 4K3SA
chains in the Genus database with same CATH superfamily
3L10A 4K3LA 3PGEB 4N94A 4K3QA 4N98A 3BEPA 3D1GA 3L10B 3L0WA 4N9AA 4RKIA 4OVFA 4S3IA 3L0WB 1MMIA 4TRTA 5FVEA 4PNVA 3RB9A 4K3MA 4TSZA 3D1EA 4MJPA 3Q4JA 4OVGA 5AH2A 4N99A 5AGUA 4TR7A 4MJRA 4OVHA 4K3KA 4TR8A 5AH4A 1UNNA 4K3PA 1JQJA 2POLA 4K3RA 4N97A 4N95A 3L0XA 5FRQA 4TR6A 3T0PA 1VPKA 3PWEA 3Q4LA 3L0XB 4K3OA 3P16A 3QSBA 3Q4KA 1JQLA 1OK7A 4N96A 3F1VA 2AWAA 3D1FA 3QSBB 5AGVA 2AVTA 4K74A 4MJQA 4PNUA 2XURA 3PGEA 4PNWA 4K3SA
chains in the Genus database with same CATH topology
3L10A 4K3LA 3PGEB 4N94A 4K3QA 4N98A 3BEPA 3D1GA 4N9AA 3L0WA 4RKIA 4OVFA 4S3IA 1MMIA 4TRTA 5FVEA 4PNVA 3RB9A 4K3MA 4TSZA 3D1EA 4MJPA 3Q4JA 4OVGA 5AH2A 4N99A 5AGUA 4TR7A 4MJRA 4OVHA 4K3KA 4TR8A 5AH4A 1UNNA 4K3PA 1JQJA 2POLA 4K3RA 4N97A 4N95A 3L0XA 5FRQA 4TR6A 3T0PA 1VPKA 3PWEA 3Q4LA 4K3OA 3P16A 3QSBA 3Q4KA 1JQLA 1OK7A 4N96A 3F1VA 2AWAA 3D1FA 3QSBB 5AGVA 2AVTA 4K74A 4MJQA 4PNUA 2XURA 4PNWA 4K3SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3L10 A;  4K3L A;  3PGE B;  4N94 A;  4K3Q A;  4N98 A;  3BEP A;  3D1G A;  4N9A A;  3L0W A;  4RKI A;  4OVF A;  4S3I A;  1MMI A;  4TRT A;  5FVE A;  4PNV A;  3RB9 A;  4K3M A;  4TSZ A;  3D1E A;  4MJP A;  3Q4J A;  4OVG A;  5AH2 A;  4N99 A;  5AGU A;  4TR7 A;  4MJR A;  4OVH A;  4K3K A;  4TR8 A;  5AH4 A;  1UNN A;  4K3P A;  1JQJ A;  2POL A;  4K3R A;  4N97 A;  4N95 A;  3L0X A;  5FRQ A;  4TR6 A;  3T0P A;  1VPK A;  3PWE A;  3Q4L A;  4K3O A;  3P16 A;  3QSB A;  3Q4K A;  1JQL A;  1OK7 A;  4N96 A;  3F1V A;  2AWA A;  3D1F A;  3QSB B;  5AGV A;  2AVT A;  4K74 A;  4MJQ A;  4PNU A;  2XUR A;  4PNW A;  4K3S A; 
#chains in the Genus database with same CATH topology
 3L10 A;  4K3L A;  3PGE B;  4N94 A;  4K3Q A;  4N98 A;  3BEP A;  3D1G A;  3L10 B;  3L0W A;  4N9A A;  4RKI A;  4OVF A;  4S3I A;  3L0W B;  1MMI A;  4TRT A;  5FVE A;  4PNV A;  3RB9 A;  4K3M A;  4TSZ A;  3D1E A;  4MJP A;  3Q4J A;  4OVG A;  5AH2 A;  4N99 A;  5AGU A;  4TR7 A;  4MJR A;  4OVH A;  4K3K A;  4TR8 A;  5AH4 A;  1UNN A;  4K3P A;  1JQJ A;  2POL A;  4K3R A;  4N97 A;  4N95 A;  3L0X A;  5FRQ A;  4TR6 A;  3T0P A;  1VPK A;  3PWE A;  3Q4L A;  3L0X B;  4K3O A;  3P16 A;  3QSB A;  3Q4K A;  1JQL A;  1OK7 A;  4N96 A;  3F1V A;  2AWA A;  3D1F A;  3QSB B;  5AGV A;  2AVT A;  4K74 A;  4MJQ A;  4PNU A;  2XUR A;  3PGE A;  4PNW A;  4K3S A; 
#chains in the Genus database with same CATH homology
 3L10 A;  4K3L A;  3PGE B;  4N94 A;  4K3Q A;  4N98 A;  3BEP A;  3D1G A;  4N9A A;  3L0W A;  4RKI A;  4OVF A;  4S3I A;  1MMI A;  4TRT A;  5FVE A;  4PNV A;  3RB9 A;  4K3M A;  4TSZ A;  3D1E A;  4MJP A;  3Q4J A;  4OVG A;  5AH2 A;  4N99 A;  5AGU A;  4TR7 A;  4MJR A;  4OVH A;  4K3K A;  4TR8 A;  5AH4 A;  1UNN A;  4K3P A;  1JQJ A;  2POL A;  4K3R A;  4N97 A;  4N95 A;  3L0X A;  5FRQ A;  4TR6 A;  3T0P A;  1VPK A;  3PWE A;  3Q4L A;  4K3O A;  3P16 A;  3QSB A;  3Q4K A;  1JQL A;  1OK7 A;  4N96 A;  3F1V A;  2AWA A;  3D1F A;  3QSB B;  5AGV A;  2AVT A;  4K74 A;  4MJQ A;  4PNU A;  2XUR A;  4PNW A;  4K3S A; 
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