4TR7A

Crystal structure of dna polymerase sliding clamp from mycobaterium tuberculosis
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
391
structure length
375
Chain Sequence
GLTDLTFRLLRESFADAVSWVAKNPVLSGVLLTGSDNGLTISGFDYEVSEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASPDIEAAVLVPAKTLAEAAKAGGGSDVRLSLGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDRPVAGLNGNGPFPAVSTDYVYLLMPVR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Mycobacterium tuberculosis
molecule keywords DNA polymerase III subunit beta
total genus 81
structure length 375
sequence length 391
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2014-06-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4tr7A01
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4tr7A02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4tr7A03
3Q4LA 4N95A 3L10A 4OVFA 4K3MA 4OVHA 4K3OA 2AWAA 3QSBB 4K3QA 4PNWA 5AH4A 4N97A 1MMIA 4TR7A 3L0XA 4MJPA 3RB9A 4S3IA 3Q4JA 3Q4KA 4PNVA 4MJRA 4TRTA 3PGEB 3F1VA 1VPKA 4OVGA 5FVEA 4N98A 3D1EA 3PWEA 4K3SA 2AVTA 4N99A 3QSBA 5AGUA 3BEPA 4K3PA 2XURA 3P16A 4RKIA 1OK7A 1UNNA 1JQLA 4TR6A 5AH2A 4K3RA 2POLA 5AGVA 3D1GA 4K3LA 4N9AA 4N94A 4MJQA 4TR8A 3T0PA 3D1FA 4K3KA 3L0WA 1JQJA 4K74A 4N96A 4TSZA 5FRQA 4PNUA
chains in the Genus database with same CATH superfamily
3Q4LA 4N95A 3L10A 4OVFA 4K3MA 4OVHA 4K3OA 2AWAA 3QSBB 4K3QA 4PNWA 5AH4A 4N97A 1MMIA 4TR7A 3L0XA 4MJPA 3RB9A 4S3IA 3Q4JA 3Q4KA 4PNVA 4MJRA 4TRTA 3PGEB 3F1VA 1VPKA 4OVGA 3L0WB 5FVEA 4N98A 3D1EA 3PWEA 4K3SA 2AVTA 4N99A 3QSBA 5AGUA 3BEPA 4K3PA 2XURA 3P16A 4RKIA 1OK7A 1UNNA 1JQLA 3L10B 4TR6A 5AH2A 4K3RA 2POLA 5AGVA 3D1GA 4K3LA 4N9AA 4N94A 4MJQA 3L0XB 4TR8A 3T0PA 3D1FA 4K3KA 3L0WA 1JQJA 4K74A 3PGEA 4N96A 4TSZA 5FRQA 4PNUA
chains in the Genus database with same CATH topology
3Q4LA 4N95A 3L10A 4OVFA 4K3MA 4OVHA 4K3OA 2AWAA 3QSBB 4K3QA 4PNWA 5AH4A 4N97A 1MMIA 4TR7A 3L0XA 4MJPA 3RB9A 4S3IA 3Q4JA 3Q4KA 4PNVA 4MJRA 4TRTA 3PGEB 3F1VA 1VPKA 4OVGA 5FVEA 4N98A 3D1EA 3PWEA 4K3SA 2AVTA 4N99A 3QSBA 5AGUA 3BEPA 4K3PA 2XURA 3P16A 4RKIA 1OK7A 1UNNA 1JQLA 4TR6A 5AH2A 4K3RA 2POLA 5AGVA 3D1GA 4K3LA 4N9AA 4N94A 4MJQA 4TR8A 3T0PA 3D1FA 4K3KA 3L0WA 1JQJA 4K74A 4N96A 4TSZA 5FRQA 4PNUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q4L A;  4N95 A;  3L10 A;  4OVF A;  4K3M A;  4OVH A;  4K3O A;  2AWA A;  3QSB B;  4K3Q A;  4PNW A;  5AH4 A;  4N97 A;  1MMI A;  4TR7 A;  3L0X A;  4MJP A;  3RB9 A;  4S3I A;  3Q4J A;  3Q4K A;  4PNV A;  4MJR A;  4TRT A;  3PGE B;  3F1V A;  1VPK A;  4OVG A;  5FVE A;  4N98 A;  3D1E A;  3PWE A;  4K3S A;  2AVT A;  4N99 A;  3QSB A;  5AGU A;  3BEP A;  4K3P A;  2XUR A;  3P16 A;  4RKI A;  1OK7 A;  1UNN A;  1JQL A;  4TR6 A;  5AH2 A;  4K3R A;  2POL A;  5AGV A;  3D1G A;  4K3L A;  4N9A A;  4N94 A;  4MJQ A;  4TR8 A;  3T0P A;  3D1F A;  4K3K A;  3L0W A;  1JQJ A;  4K74 A;  4N96 A;  4TSZ A;  5FRQ A;  4PNU A; 
#chains in the Genus database with same CATH topology
 3Q4L A;  4N95 A;  3L10 A;  4OVF A;  4K3M A;  4OVH A;  4K3O A;  2AWA A;  3QSB B;  4K3Q A;  4PNW A;  5AH4 A;  4N97 A;  1MMI A;  4TR7 A;  3L0X A;  4MJP A;  3RB9 A;  4S3I A;  3Q4J A;  3Q4K A;  4PNV A;  4MJR A;  4TRT A;  3PGE B;  3F1V A;  1VPK A;  4OVG A;  3L0W B;  5FVE A;  4N98 A;  3D1E A;  3PWE A;  4K3S A;  2AVT A;  4N99 A;  3QSB A;  5AGU A;  3BEP A;  4K3P A;  2XUR A;  3P16 A;  4RKI A;  1OK7 A;  1UNN A;  1JQL A;  3L10 B;  4TR6 A;  5AH2 A;  4K3R A;  2POL A;  5AGV A;  3D1G A;  4K3L A;  4N9A A;  4N94 A;  4MJQ A;  3L0X B;  4TR8 A;  3T0P A;  3D1F A;  4K3K A;  3L0W A;  1JQJ A;  4K74 A;  3PGE A;  4N96 A;  4TSZ A;  5FRQ A;  4PNU A; 
#chains in the Genus database with same CATH homology
 3Q4L A;  4N95 A;  3L10 A;  4OVF A;  4K3M A;  4OVH A;  4K3O A;  2AWA A;  3QSB B;  4K3Q A;  4PNW A;  5AH4 A;  4N97 A;  1MMI A;  4TR7 A;  3L0X A;  4MJP A;  3RB9 A;  4S3I A;  3Q4J A;  3Q4K A;  4PNV A;  4MJR A;  4TRT A;  3PGE B;  3F1V A;  1VPK A;  4OVG A;  5FVE A;  4N98 A;  3D1E A;  3PWE A;  4K3S A;  2AVT A;  4N99 A;  3QSB A;  5AGU A;  3BEP A;  4K3P A;  2XUR A;  3P16 A;  4RKI A;  1OK7 A;  1UNN A;  1JQL A;  4TR6 A;  5AH2 A;  4K3R A;  2POL A;  5AGV A;  3D1G A;  4K3L A;  4N9A A;  4N94 A;  4MJQ A;  4TR8 A;  3T0P A;  3D1F A;  4K3K A;  3L0W A;  1JQJ A;  4K74 A;  4N96 A;  4TSZ A;  5FRQ A;  4PNU A; 
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